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8PW2
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BU of 8pw2 by Molmil
Protein p6 from bacteriophage phi29, C-terminal delta31 truncated version
Descriptor: Histone-like protein p6
Authors:Alcorlo Pages, M, Hermoso Dominguez, J.
Deposit date:2023-07-19
Release date:2024-01-17
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (1.59 Å)
Cite:Flexible structural arrangement and DNA-binding properties of protein p6 from Bacillus subtillis phage phi 29.
Nucleic Acids Res., 52, 2024
8PW4
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BU of 8pw4 by Molmil
Protein p6 from bacteriophage phi29, C-terminal delta20 truncated version
Descriptor: Histone-like protein p6
Authors:Alcorlo Pages, M, Hermoso Dominguez, J.
Deposit date:2023-07-19
Release date:2024-01-17
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Flexible structural arrangement and DNA-binding properties of protein p6 from Bacillus subtillis phage phi 29.
Nucleic Acids Res., 52, 2024
7A54
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BU of 7a54 by Molmil
Two copies of the catalytic domain of NanA sialidase from Streptococcus pneumoniae juxtaposed in the P212121 space group, in complex with DANA
Descriptor: 2-DEOXY-2,3-DEHYDRO-N-ACETYL-NEURAMINIC ACID, Sialidase A
Authors:Bridot, C, Bouckaert, J.
Deposit date:2020-08-20
Release date:2020-11-18
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Polyvalent Transition-State Analogues of Sialyl Substrates Strongly Inhibit Bacterial Sialidases*.
Chemistry, 27, 2021
8PM4
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BU of 8pm4 by Molmil
Cryo-EM structure of the Cas12m-crRNA-target DNA complex
Descriptor: DNA oligoduplex, non-target strand, chain D, ...
Authors:Sasnauskas, G, Tamulaitiene, G, Karvelis, T, Bigelyte, G, Siksnys, V.
Deposit date:2023-06-28
Release date:2024-02-07
Last modified:2024-11-13
Method:ELECTRON MICROSCOPY (2.93 Å)
Cite:Innate programmable DNA binding by CRISPR-Cas12m effectors enable efficient base editing.
Nucleic Acids Res., 52, 2024
6ZJ8
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BU of 6zj8 by Molmil
Structure of the PAS domain from Bordetella pertussis BvgS
Descriptor: Virulence sensor protein BvgS
Authors:Clantin, B, Dupre, E, Jacob-Dubuisson, F, Villeret, V.
Deposit date:2020-06-28
Release date:2020-11-11
Last modified:2024-06-19
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structural insight into the role of the PAS domainfor signal transduction in sensor-kinase BvgS.
J.Bacteriol., 203, 2021
6X22
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BU of 6x22 by Molmil
PDZ domain from choanoflagellate GIPC (mbGIPC) bound to GAIP peptide
Descriptor: mbGIPC protein
Authors:Gao, M, Amacher, J.F.
Deposit date:2020-05-19
Release date:2020-11-25
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.402 Å)
Cite:Structural characterization and computational analysis of PDZ domains in Monosiga brevicollis.
Protein Sci., 29, 2020
6X1X
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BU of 6x1x by Molmil
PDZ domain from choanoflagellate GIPC (mbGIPC)
Descriptor: GLYCEROL, mbGIPC protein
Authors:Gao, M, Amacher, J.F.
Deposit date:2020-05-19
Release date:2020-11-25
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.198 Å)
Cite:Structural characterization and computational analysis of PDZ domains in Monosiga brevicollis.
Protein Sci., 29, 2020
6X23
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BU of 6x23 by Molmil
PDZ domain from choanoflagellate SHANK1 (mbSHANK1) bound to GIRK3 peptide
Descriptor: G protein-activated inward rectifier potassium channel 3, mbSHANK1 protein
Authors:Gao, M, Mackley, I.G.P, Amacher, J.F.
Deposit date:2020-05-19
Release date:2020-11-25
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (2.154 Å)
Cite:Structural characterization and computational analysis of PDZ domains in Monosiga brevicollis.
Protein Sci., 29, 2020
6X1P
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BU of 6x1p by Molmil
Crystal Structure of Choanoflagellate (Monosiga brevicollis) Dlg1 PDZ2 (mbDLG-2) in spacegroup I2
Descriptor: mbDLG protein
Authors:Bamonte, H.A, Amacher, J.F.
Deposit date:2020-05-19
Release date:2020-11-25
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.702 Å)
Cite:Structural characterization and computational analysis of PDZ domains in Monosiga brevicollis.
Protein Sci., 29, 2020
6X1R
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BU of 6x1r by Molmil
Crystal Structure of Choanoflagellate (Monosiga brevicollis) Dlg1 PDZ2 (mbDLG-2) in spacegroup P212121
Descriptor: GLYCEROL, mbDLG protein
Authors:Bamonte, H.A, Amacher, J.F.
Deposit date:2020-05-19
Release date:2020-11-25
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.3 Å)
Cite:Structural characterization and computational analysis of PDZ domains in Monosiga brevicollis.
Protein Sci., 29, 2020
6WTQ
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BU of 6wtq by Molmil
Human JAK2 JH1 domain in complex with PROTAC-intermediate linker handle 4
Descriptor: 1,2-ETHANEDIOL, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, N-methyl-4-{[4-(1-propyl-1H-pyrazol-4-yl)-7H-pyrrolo[2,3-d]pyrimidin-2-yl]amino}benzamide, ...
Authors:Yu, S, Nithianantham, S, Fischer, M.
Deposit date:2020-05-03
Release date:2021-05-05
Last modified:2024-10-09
Method:X-RAY DIFFRACTION (1.79968476 Å)
Cite:Degradation of Janus kinases in CRLF2-rearranged acute lymphoblastic leukemia.
Blood, 138, 2021
6WTN
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BU of 6wtn by Molmil
Human JAK2 JH1 domain in complex with Ruxolitinib
Descriptor: (3R)-3-cyclopentyl-3-[4-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)-1H-pyrazol-1-yl]propanenitrile, 1,2-ETHANEDIOL, Tyrosine-protein kinase JAK2
Authors:Yu, S, Nithianantham, S, Fischer, M.
Deposit date:2020-05-03
Release date:2021-05-05
Last modified:2024-10-23
Method:X-RAY DIFFRACTION (1.83 Å)
Cite:Degradation of Janus kinases in CRLF2-rearranged acute lymphoblastic leukemia.
Blood, 138, 2021
6WTP
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BU of 6wtp by Molmil
Human JAK2 JH1 domain in complex with PROTAC-intermediate linker handle 3
Descriptor: GLYCEROL, Tyrosine-protein kinase JAK2, tert-butyl 4-[(4-{1-[3-(cyanomethyl)-1-(ethylsulfonyl)azetidin-3-yl]-1H-pyrazol-4-yl}-7H-pyrrolo[2,3-d]pyrimidin-2-yl)amino]benzoate
Authors:Yu, S, Nithianantham, S, Fischer, M.
Deposit date:2020-05-03
Release date:2021-05-05
Last modified:2024-10-09
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Degradation of Janus kinases in CRLF2-rearranged acute lymphoblastic leukemia.
Blood, 138, 2021
6WTO
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BU of 6wto by Molmil
Human JAK2 JH1 domain in complex with Baricitinib
Descriptor: 1,2-ETHANEDIOL, Baricitinib, Tyrosine-protein kinase JAK2
Authors:Yu, S, Nithianantham, S, Fischer, M.
Deposit date:2020-05-03
Release date:2021-05-05
Last modified:2024-11-06
Method:X-RAY DIFFRACTION (1.74 Å)
Cite:Degradation of Janus kinases in CRLF2-rearranged acute lymphoblastic leukemia.
Blood, 138, 2021
7QUO
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BU of 7quo by Molmil
FimH lectin domain in complex with oligomannose-6
Descriptor: FimH, NICKEL (II) ION, SULFATE ION, ...
Authors:Bouckaert, J, Bourenkov, G.P.
Deposit date:2022-01-18
Release date:2023-02-01
Last modified:2024-10-23
Method:X-RAY DIFFRACTION (3 Å)
Cite:Structural insights into a cooperative switch between one and two FimH bacterial adhesins binding pauci- and high-mannose type N-glycan receptors
J.Biol.Chem., 299, 2023
6X1N
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BU of 6x1n by Molmil
Crystal Structure of Choanoflagellate (Monosiga brevicollis) Dlg1 PDZ3 (mbDLG-3)
Descriptor: GLYCEROL, mbDLG-3 protein
Authors:Mackley, I, Amacher, J.F.
Deposit date:2020-05-19
Release date:2020-11-25
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:Structural characterization and computational analysis of PDZ domains in Monosiga brevicollis.
Protein Sci., 29, 2020
6X20
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BU of 6x20 by Molmil
PDZ domain from choanoflagellate GIPC (mbGIPC) bound to B1AR peptide
Descriptor: mbGIPC protein
Authors:Gao, M, Amacher, J.F.
Deposit date:2020-05-19
Release date:2020-11-25
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.402 Å)
Cite:Structural characterization and computational analysis of PDZ domains in Monosiga brevicollis.
Protein Sci., 29, 2020
3KRR
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BU of 3krr by Molmil
Crystal Structure of JAK2 complexed with a potent quinoxaline ATP site inhibitor
Descriptor: 8-[3,5-difluoro-4-(morpholin-4-ylmethyl)phenyl]-2-(1-piperidin-4-yl-1H-pyrazol-4-yl)quinoxaline, Tyrosine-protein kinase JAK2
Authors:Tavares, G.A, Gerspacher, M, Kroemer, M, Scheufler, C.
Deposit date:2009-11-19
Release date:2010-07-21
Last modified:2024-10-09
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Potent and Selective Inhibition of Polycythemia by the Quinoxaline JAK2 Inhibitor NVP-BSK805
Mol.Cancer Ther., 9, 2010
4JT8
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BU of 4jt8 by Molmil
Crystal Structure of human SIRT3 with ELT inhibitor 28 [4-(4-{2-[(2,2-dimethylpropanoyl)amino]ethyl}piperidin-1-yl)thieno[3,2-d]pyrimidine-6-carboxamide[
Descriptor: 4-(4-{2-[(2,2-dimethylpropanoyl)amino]ethyl}piperidin-1-yl)thieno[3,2-d]pyrimidine-6-carboxamide, NAD-dependent protein deacetylase sirtuin-3, mitochondrial, ...
Authors:Dai, H.
Deposit date:2013-03-22
Release date:2013-04-24
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.26 Å)
Cite:Discovery of Thieno[3,2-d]pyrimidine-6-carboxamides as Potent Inhibitors of SIRT1, SIRT2, and SIRT3.
J.Med.Chem., 56, 2013
7Q55
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BU of 7q55 by Molmil
Single Particle Cryo-EM structure of photosynthetic A8B8 glyceraldehyde-3-phosphate dehydrogenase hexadecamer (major conformer) from Spinacia oleracia.
Descriptor: Glyceraldehyde-3-phosphate dehydrogenase A, chloroplastic, Glyceraldehyde-3-phosphate dehydrogenase B, ...
Authors:Marotta, R, Fermani, S, Sparla, F, Trost, P, Del Giudice, A.
Deposit date:2021-11-02
Release date:2022-11-16
Last modified:2024-11-06
Method:ELECTRON MICROSCOPY (5.7 Å)
Cite:Unravelling the regulation pathway of photosynthetic AB-GAPDH.
Acta Crystallogr D Struct Biol, 78, 2022
7Q56
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BU of 7q56 by Molmil
Single Particle Cryo-EM structure of photosynthetic A8B8 glyceraldehyde-3-phosphate dehydrogenase (minor conformer) from Spinacia oleracea.
Descriptor: Glyceraldehyde-3-phosphate dehydrogenase A, chloroplastic, Glyceraldehyde-3-phosphate dehydrogenase B, ...
Authors:Marotta, R, Fermani, S, Sparla, F, Trost, P, Del Giudice, A.
Deposit date:2021-11-02
Release date:2022-11-16
Last modified:2024-11-06
Method:ELECTRON MICROSCOPY (7.1 Å)
Cite:Unravelling the regulation pathway of photosynthetic AB-GAPDH.
Acta Crystallogr D Struct Biol, 78, 2022
7Q54
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BU of 7q54 by Molmil
Single Particle Cryo-EM structure of photosynthetic A4B4-glyceraldehyde 3-phosphate dehydrogenase from Spinacia oleracia.
Descriptor: Glyceraldehyde-3-phosphate dehydrogenase A, chloroplastic, Glyceraldehyde-3-phosphate dehydrogenase B, ...
Authors:Marotta, R, Fermani, S, Sparla, F, Trost, P, Del Giudice, A.
Deposit date:2021-11-02
Release date:2022-11-16
Last modified:2024-11-13
Method:ELECTRON MICROSCOPY (8.9 Å)
Cite:Unravelling the regulation pathway of photosynthetic AB-GAPDH.
Acta Crystallogr D Struct Biol, 78, 2022
7Q57
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BU of 7q57 by Molmil
Single Particle Cryo-EM structure of photosynthetic A10B10 glyceraldehyde-3-phospahte dehydrogenase from Spinacia oleracea.
Descriptor: Glyceraldehyde-3-phosphate dehydrogenase A, chloroplastic,Glyceraldehyde-3-phosphate dehydrogenase A, chloroplastic, ...
Authors:Marotta, R, Fermani, S, Sparla, F, Trost, P, Del Giudice, A.
Deposit date:2021-11-02
Release date:2022-11-16
Last modified:2024-07-17
Method:ELECTRON MICROSCOPY (13 Å)
Cite:Unravelling the regulation pathway of photosynthetic AB-GAPDH.
Acta Crystallogr D Struct Biol, 78, 2022
7Q53
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BU of 7q53 by Molmil
Single Particle Cryo-EM structure of photosynthetic A2B2 glyceraldehyde 3-phosphate dehydrogenase from Spinacia oleracia
Descriptor: Glyceraldehyde-3-phosphate dehydrogenase A, chloroplastic,Glyceraldehyde-3-phosphate dehydrogenase A, chloroplastic, ...
Authors:Marotta, R, Fermani, S, Sparla, F, Trost, P, Del Giudice, A.
Deposit date:2021-11-02
Release date:2022-11-16
Last modified:2024-07-17
Method:ELECTRON MICROSCOPY (6.3 Å)
Cite:Unravelling the regulation pathway of photosynthetic AB-GAPDH.
Acta Crystallogr D Struct Biol, 78, 2022
7ZTY
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BU of 7zty by Molmil
Structure of Vps39 N-terminal domain from Chaetomium thermophilum
Descriptor: CNH domain-containing protein
Authors:Kiontke, S, Ungermann, C, Kuemmel, D.
Deposit date:2022-05-11
Release date:2022-09-21
Last modified:2024-11-20
Method:X-RAY DIFFRACTION (2.89 Å)
Cite:Structure of the HOPS tethering complex, a lysosomal membrane fusion machinery.
Elife, 11, 2022

229380

数据于2024-12-25公开中

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