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8UHN
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BU of 8uhn by Molmil
anti-Phosphohistidine Fab hSC44.ck.20.N32F with 3pHis peptide
Descriptor: 1,2-ETHANEDIOL, 3pHis peptide, ACETATE ION, ...
Authors:Kalagiri, R, Stanfield, R.L, Hunter, T, Wilson, I.A.
Deposit date:2023-10-09
Release date:2025-03-19
Method:X-RAY DIFFRACTION (2.09 Å)
Cite:Using phage display for rational engineering of a higher affinity humanized 3' phosphohistidine-specific antibody.
Biorxiv, 2024
8UIG
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BU of 8uig by Molmil
anti-Phosphohistidine Fab hSC44.ck.20 with 3pHis peptide
Descriptor: 3pHis peptide, hSC44.ck.20 Fab heavy chain, hSC44.ck.20 Fab light chain
Authors:Kalagiri, R, Stanfield, R.L, Hunter, T, Wilson, I.A.
Deposit date:2023-10-10
Release date:2025-03-19
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Using phage display for rational engineering of a higher affinity humanized 3' phosphohistidine-specific antibody.
Biorxiv, 2024
8UIT
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BU of 8uit by Molmil
anti-Phosphohistidine Fab hSC44.ck with 3pHis peptide
Descriptor: 3pHis peptide, hSC44.ck Fab heavy chain, hSC44.ck Fab light chain
Authors:Kalagiri, R, Stanfield, R.L, Hunter, T, Wilson, I.A.
Deposit date:2023-10-10
Release date:2025-03-19
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Using phage display for rational engineering of a higher affinity humanized 3' phosphohistidine-specific antibody.
Biorxiv, 2024
8UJI
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BU of 8uji by Molmil
anti-Phosphohistidine Fab hSC44.ck with 3pTza peptide
Descriptor: 1,2-ETHANEDIOL, 3-pTza peptide, hSC44.CK Fab heavy chain, ...
Authors:Kalagiri, R, Stanfield, R.L, Hunter, T, Wilson, I.A.
Deposit date:2023-10-11
Release date:2025-03-19
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Using phage display for rational engineering of a higher affinity humanized 3' phosphohistidine-specific antibody.
Biorxiv, 2024
1ZHN
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BU of 1zhn by Molmil
Crystal Structure of mouse CD1d bound to the self ligand phosphatidylcholine
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 7-[(DODECANOYLOXY)METHYL]-4-HYDROXY-N,N,N-TRIMETHYL-9-OXO-3,5,8-TRIOXA-4-PHOSPHADOTRIACONTAN-1-AMINIUM 4-OXIDE, CD1d1 antigen, ...
Authors:Giabbai, B, Sidobre, S, Crispin, M.M.D, Sanchez Ruiz, Y, Bachi, A, Kronenberg, M, Wilson, I.A, Degano, M.
Deposit date:2005-04-26
Release date:2005-07-19
Last modified:2024-10-30
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Crystal structure of mouse CD1d bound to the self ligand phosphatidylcholine: a molecular basis for NKT cell activation
J.Immunol., 175, 2005
25C8
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BU of 25c8 by Molmil
CATALYTIC ANTIBODY 5C8, FAB-HAPTEN COMPLEX
Descriptor: IGG 5C8, N-METHYL-N-(PARA-GLUTARAMIDOPHENYL-ETHYL)-PIPERIDINIUM ION
Authors:Gruber, K, Wilson, I.A.
Deposit date:1998-03-18
Release date:1999-03-23
Last modified:2024-11-20
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural basis for antibody catalysis of a disfavored ring closure reaction.
Biochemistry, 38, 1999
6XKQ
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BU of 6xkq by Molmil
Crystal structure of SARS-CoV-2 receptor binding domain in complex with neutralizing antibody CV07-250
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, CV07-250 Heavy Chain, CV07-250 Light Chain, ...
Authors:Yuan, M, Liu, H, Zhu, X, Wu, N.C, Wilson, I.A.
Deposit date:2020-06-26
Release date:2020-10-14
Last modified:2024-10-23
Method:X-RAY DIFFRACTION (2.55 Å)
Cite:A Therapeutic Non-self-reactive SARS-CoV-2 Antibody Protects from Lung Pathology in a COVID-19 Hamster Model.
Cell, 183, 2020
6XKP
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BU of 6xkp by Molmil
Crystal structure of SARS-CoV-2 receptor binding domain in complex with neutralizing antibody CV07-270
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, CV07-270 Heavy Chain, CV07-270 Light Chain, ...
Authors:Liu, H, Yuan, M, Zhu, X, Wu, N.C, Wilson, I.A.
Deposit date:2020-06-26
Release date:2020-10-14
Last modified:2024-10-09
Method:X-RAY DIFFRACTION (2.72 Å)
Cite:A Therapeutic Non-self-reactive SARS-CoV-2 Antibody Protects from Lung Pathology in a COVID-19 Hamster Model.
Cell, 183, 2020
7SBU
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BU of 7sbu by Molmil
Crystal structure of SARS-CoV-2 spike protein receptor-binding domain in complex with a highly potent antibody J08 Fab
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, GLYCEROL, J08 Fab heavy chain, ...
Authors:Liu, H, Wilson, I.A.
Deposit date:2021-09-25
Release date:2022-05-11
Last modified:2024-11-13
Method:X-RAY DIFFRACTION (2.53 Å)
Cite:Structural insights of a highly potent pan-neutralizing SARS-CoV-2 human monoclonal antibody.
Proc.Natl.Acad.Sci.USA, 119, 2022
7TP3
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BU of 7tp3 by Molmil
Crystal structure of SARS-CoV-2 receptor binding domain in complex with neutralizing antibody K288.2
Descriptor: CACODYLATE ION, K288.2 heavy chain, K288.2 light chain, ...
Authors:Yuan, M, Zhu, X, Wilson, I.A.
Deposit date:2022-01-24
Release date:2022-02-23
Last modified:2024-10-30
Method:X-RAY DIFFRACTION (2.33 Å)
Cite:Broadly neutralizing antibodies to SARS-related viruses can be readily induced in rhesus macaques.
Sci Transl Med, 14, 2022
7TP4
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BU of 7tp4 by Molmil
Crystal structure of SARS-CoV-2 receptor binding domain in complex with neutralizing antibody K398.22
Descriptor: 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, K398.22 heavy chain, ...
Authors:Yuan, M, Zhu, X, Wilson, I.A.
Deposit date:2022-01-24
Release date:2022-02-23
Last modified:2024-11-13
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Broadly neutralizing antibodies to SARS-related viruses can be readily induced in rhesus macaques.
Sci Transl Med, 14, 2022
7TI6
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BU of 7ti6 by Molmil
Crystal structure of the wild-type least mutated common ancestor (LMCA) of the HIV-targeting PCT64 antibody lineage
Descriptor: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, PCT64_LMCA Fab heavy chain, PCT64_LMCA light chain (wild type)
Authors:Omorodion, O, Wilson, I.A.
Deposit date:2022-01-12
Release date:2022-10-05
Last modified:2024-10-23
Method:X-RAY DIFFRACTION (2.64 Å)
Cite:Human immunoglobulin repertoire analysis guides design of vaccine priming immunogens targeting HIV V2-apex broadly neutralizing antibody precursors.
Immunity, 55, 2022
7T7B
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BU of 7t7b by Molmil
Crystal structure of SARS-CoV-2 spike protein receptor-binding domain in complex with a cross-neutralizing antibody ADI-62113 Fab
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ADI-62113 Fab heavy chain, ADI-62113 Fab light chain, ...
Authors:Liu, H, Wilson, I.A.
Deposit date:2021-12-14
Release date:2022-08-03
Last modified:2024-10-30
Method:X-RAY DIFFRACTION (2.59 Å)
Cite:Human antibodies to SARS-CoV-2 with a recurring YYDRxG motif retain binding and neutralization to variants of concern including Omicron.
Commun Biol, 5, 2022
7U8L
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BU of 7u8l by Molmil
Crystal structure of chimeric hemagglutinin cH15/3 in complex with broad protective antibody 31.a.83
Descriptor: Antibody Fab light chain, Hemagglutinin HA1 subunit, Hemagglutinin HA2 subunit, ...
Authors:Zhu, X, Wilson, I.A.
Deposit date:2022-03-08
Release date:2022-06-08
Last modified:2024-10-16
Method:X-RAY DIFFRACTION (4.56 Å)
Cite:Influenza chimeric hemagglutinin structures in complex with broadly protective antibodies to the stem and trimer interface.
Proc.Natl.Acad.Sci.USA, 119, 2022
7SJS
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BU of 7sjs by Molmil
Crystal structure of SARS-CoV-2 spike stem helix peptide in complex with neutralizing antibody CC40.8
Descriptor: ACETATE ION, CC40.8 Fab heavy chain, CC40.8 Fab light chain, ...
Authors:Yuan, M, Wilson, I.A.
Deposit date:2021-10-18
Release date:2022-01-12
Last modified:2024-10-23
Method:X-RAY DIFFRACTION (1.612 Å)
Cite:A human antibody reveals a conserved site on beta-coronavirus spike proteins and confers protection against SARS-CoV-2 infection.
Sci Transl Med, 14, 2022
7T1V
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BU of 7t1v by Molmil
Crystal structure of an equine H7 hemagglutinin from A/equine/NY/49/73 (H7N7) in complex with 3'-GcLN
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin HA1 chain, ...
Authors:Zhu, X, Wilson, I.A.
Deposit date:2021-12-02
Release date:2022-01-12
Last modified:2024-11-13
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:N -Glycolylneuraminic Acid Binding of Avian and Equine H7 Influenza A Viruses.
J.Virol., 96, 2022
7U8M
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BU of 7u8m by Molmil
Crystal structure of chimeric hemagglutinin cH15/3 in complex with broad protective antibodies 31.a.83 and FluA-20
Descriptor: Antibody 31.a.83 Fab light chain, antibody 31.a.83 Fab heavy chain, antibody FluA-20 Fab heavy chain, ...
Authors:Zhu, X, Wilson, I.A.
Deposit date:2022-03-08
Release date:2022-06-08
Last modified:2024-11-13
Method:X-RAY DIFFRACTION (5.39 Å)
Cite:Influenza chimeric hemagglutinin structures in complex with broadly protective antibodies to the stem and trimer interface.
Proc.Natl.Acad.Sci.USA, 119, 2022
7U8J
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BU of 7u8j by Molmil
Crystal structure of chimeric hemagglutinin cH4/3 in complex with broad protective antibody 31.a.83
Descriptor: Antibody Fab light chain, Hemagglutinin HA1 subunit, Hemagglutinin HA2 subunit, ...
Authors:Zhu, X, Wilson, I.A.
Deposit date:2022-03-08
Release date:2022-06-08
Last modified:2024-10-23
Method:X-RAY DIFFRACTION (4.9 Å)
Cite:Influenza chimeric hemagglutinin structures in complex with broadly protective antibodies to the stem and trimer interface.
Proc.Natl.Acad.Sci.USA, 119, 2022
7U0K
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BU of 7u0k by Molmil
IOMA class antibody Fab ACS124
Descriptor: 2-[N-CYCLOHEXYLAMINO]ETHANE SULFONIC ACID, IOMA Class antibody ACS124 Heavy chain, IOMA Class antibody ACS124 Light chain
Authors:Farokhi, E, Stanfield, R.L, Wilson, I.A.
Deposit date:2022-02-18
Release date:2022-08-24
Last modified:2024-10-09
Method:X-RAY DIFFRACTION (1.73 Å)
Cite:Identification of IOMA-class neutralizing antibodies targeting the CD4-binding site on the HIV-1 envelope glycoprotein.
Nat Commun, 13, 2022
7U04
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BU of 7u04 by Molmil
IOMA class antibody ACS101
Descriptor: GLYCEROL, IOMA class antibody ACS101 heavy chain, IOMA class antibody ACS101 light chain
Authors:Farokhi, E, Stanfield, R.L, Wilson, I.A.
Deposit date:2022-02-17
Release date:2022-08-24
Last modified:2024-10-23
Method:X-RAY DIFFRACTION (2.31 Å)
Cite:Identification of IOMA-class neutralizing antibodies targeting the CD4-binding site on the HIV-1 envelope glycoprotein.
Nat Commun, 13, 2022
7U5G
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BU of 7u5g by Molmil
ACS122 Fab
Descriptor: ACS122 Fab Heavy chain, ACS122 Fab Light chain
Authors:Farokhi, E, Stanfield, R.L, Wilson, I.A.
Deposit date:2022-03-02
Release date:2022-11-02
Last modified:2024-11-20
Method:X-RAY DIFFRACTION (1.84 Å)
Cite:Complementary antibody lineages achieve neutralization breadth in an HIV-1 infected elite neutralizer.
Plos Pathog., 18, 2022
2YMN
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BU of 2ymn by Molmil
Organization of the Influenza Virus Replication Machinery
Descriptor: NUCLEOPROTEIN
Authors:Moeller, A, Kirchdoerfer, R.N, Potter, C.S, Carragher, B, Wilson, I.A.
Deposit date:2012-10-09
Release date:2012-12-05
Last modified:2024-05-08
Method:ELECTRON MICROSCOPY (20 Å)
Cite:Organization of the Influenza Virus Replication Machinery.
Science, 338, 2012
1GRC
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BU of 1grc by Molmil
CRYSTAL STRUCTURE OF GLYCINAMIDE RIBONUCLEOTIDE TRANSFORMYLASE FROM ESCHERICHIA COLI AT 3.0 ANGSTROMS RESOLUTION: A TARGET ENZYME FOR CHEMOTHERAPY
Descriptor: GLYCINAMIDE RIBONUCLEOTIDE TRANSFORMYLASE, PHOSPHATE ION
Authors:Chen, P, Wilson, I.A.
Deposit date:1992-07-21
Release date:1993-10-31
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (3 Å)
Cite:Crystal structure of glycinamide ribonucleotide transformylase from Escherichia coli at 3.0 A resolution. A target enzyme for chemotherapy.
J.Mol.Biol., 227, 1992
1HIN
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BU of 1hin by Molmil
STRUCTURAL EVIDENCE FOR INDUCED FIT AS A MECHANISM FOR ANTIBODY-ANTIGEN RECOGNITION
Descriptor: IGG2A-KAPPA 17/9 FAB (HEAVY CHAIN), IGG2A-KAPPA 17/9 FAB (LIGHT CHAIN), INFLUENZA HEMAGGLUTININ HA1 (STRAIN X47) (RESIDUES 100-107)
Authors:Rini, J.M, Wilson, I.A.
Deposit date:1992-07-08
Release date:1994-01-31
Last modified:2024-11-13
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Structural evidence for induced fit as a mechanism for antibody-antigen recognition.
Science, 255, 1992
1HIM
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BU of 1him by Molmil
STRUCTURAL EVIDENCE FOR INDUCED FIT AS A MECHANISM FOR ANTIBODY-ANTIGEN RECOGNITION
Descriptor: IGG2A-KAPPA 17/9 FAB (HEAVY CHAIN), IGG2A-KAPPA 17/9 FAB (LIGHT CHAIN), INFLUENZA HEMAGGLUTININ HA1 (STRAIN X47) (RESIDUES 100-108)
Authors:Schulze-Gahmen, U, Wilson, I.A.
Deposit date:1992-07-08
Release date:1994-01-31
Last modified:2024-11-20
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Structural evidence for induced fit as a mechanism for antibody-antigen recognition.
Science, 255, 1992

239149

数据于2025-07-23公开中

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