6LKG
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![BU of 6lkg by Molmil](/molmil-images/mine/6lkg) | two-component system protein mediate signal transduction | Descriptor: | 6-O-phosphono-alpha-D-glucopyranose, ABC transporter, solute-binding protein, ... | Authors: | Wang, M, Tao, Y. | Deposit date: | 2019-12-19 | Release date: | 2020-12-02 | Last modified: | 2024-03-27 | Method: | X-RAY DIFFRACTION (1.948 Å) | Cite: | Interface switch mediates signal transmission in a two-component system. Proc.Natl.Acad.Sci.USA, 117, 2020
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6LKK
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![BU of 6lkk by Molmil](/molmil-images/mine/6lkk) | Two-component system protein mediate signal transduction | Descriptor: | 6-O-phosphono-alpha-D-glucopyranose, ABC transporter, solute-binding protein | Authors: | Wang, M, Tao, Y. | Deposit date: | 2019-12-19 | Release date: | 2020-12-02 | Last modified: | 2024-03-27 | Method: | X-RAY DIFFRACTION (1.502 Å) | Cite: | Interface switch mediates signal transmission in a two-component system. Proc.Natl.Acad.Sci.USA, 117, 2020
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6LKL
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![BU of 6lkl by Molmil](/molmil-images/mine/6lkl) | Two-component system protein mediate signal transduction | Descriptor: | ABC transporter, solute-binding protein, MALONIC ACID | Authors: | Wang, M, Tao, Y. | Deposit date: | 2019-12-19 | Release date: | 2020-12-02 | Last modified: | 2024-03-27 | Method: | X-RAY DIFFRACTION (2.213 Å) | Cite: | Interface switch mediates signal transmission in a two-component system. Proc.Natl.Acad.Sci.USA, 117, 2020
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7W1N
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![BU of 7w1n by Molmil](/molmil-images/mine/7w1n) | Complex structure of a leaf-branch compost cutinase variant LCC ICCG_KRP | Descriptor: | 1,2-ETHANEDIOL, BICINE, Leaf-branch compost cutinase | Authors: | Niu, D, Zeng, W, Huang, J.W, Chen, C.C, Liu, W.D, Guo, R.T. | Deposit date: | 2021-11-19 | Release date: | 2022-03-09 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.88 Å) | Cite: | Substrate-Binding Mode of a Thermophilic PET Hydrolase and Engineering the Enzyme to Enhance the Hydrolytic Efficacy. Acs Catalysis, 12, 2022
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7W44
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![BU of 7w44 by Molmil](/molmil-images/mine/7w44) | Complex structure of a leaf-branch compost cutinase variant LCC ICCG_RIP | Descriptor: | 1,2-ETHANEDIOL, IMIDAZOLE, Leaf-branch compost cutinase | Authors: | Niu, D, Zeng, W, Huang, J.W, Chen, C.C, Liu, W.D, Guo, R.T. | Deposit date: | 2021-11-26 | Release date: | 2022-03-09 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.85 Å) | Cite: | Substrate-Binding Mode of a Thermophilic PET Hydrolase and Engineering the Enzyme to Enhance the Hydrolytic Efficacy. Acs Catalysis, 12, 2022
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7W45
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![BU of 7w45 by Molmil](/molmil-images/mine/7w45) | Complex structure of a leaf-branch compost cutinase variant LCC ICCG_KIP | Descriptor: | CALCIUM ION, Leaf-branch compost cutinase, SODIUM ION | Authors: | Niu, D, Zeng, W, Huang, J.W, Chen, C.C, Liu, W.D, Guo, R.T. | Deposit date: | 2021-11-26 | Release date: | 2022-03-09 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.94 Å) | Cite: | Substrate-Binding Mode of a Thermophilic PET Hydrolase and Engineering the Enzyme to Enhance the Hydrolytic Efficacy. Acs Catalysis, 12, 2022
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6LKI
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![BU of 6lki by Molmil](/molmil-images/mine/6lki) | Two-component system protein mediate signal transduction | Descriptor: | ABC transporter, solute-binding protein, MALONIC ACID, ... | Authors: | Wang, M, Tao, Y. | Deposit date: | 2019-12-19 | Release date: | 2020-12-02 | Last modified: | 2024-03-27 | Method: | X-RAY DIFFRACTION (1.781 Å) | Cite: | Interface switch mediates signal transmission in a two-component system. Proc.Natl.Acad.Sci.USA, 117, 2020
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6LXY
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![BU of 6lxy by Molmil](/molmil-images/mine/6lxy) | IRAK4 in complex with inhibitor | Descriptor: | Interleukin-1 receptor-associated kinase 4, N-[(2R)-2-fluoranyl-3-methyl-3-oxidanyl-butyl]-6-[(6-fluoranylpyrazolo[1,5-a]pyrimidin-5-yl)amino]-4-(propan-2-ylamino)pyridine-3-carboxamide, SULFATE ION | Authors: | Ghosh, K, Bose, S. | Deposit date: | 2020-02-12 | Release date: | 2020-11-25 | Method: | X-RAY DIFFRACTION (2.19 Å) | Cite: | Optimization of Nicotinamides as Potent and Selective IRAK4 Inhibitors with Efficacy in a Murine Model of Psoriasis. Acs Med.Chem.Lett., 11, 2020
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6LKH
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![BU of 6lkh by Molmil](/molmil-images/mine/6lkh) | Two-component system protein mediate signal transduction | Descriptor: | 6-O-phosphono-alpha-D-glucopyranose, ABC transporter, solute-binding protein, ... | Authors: | Wang, M, Tao, Y. | Deposit date: | 2019-12-19 | Release date: | 2021-03-17 | Last modified: | 2024-05-29 | Method: | X-RAY DIFFRACTION (2.534 Å) | Cite: | Interface switch mediates signal transmission in a two-component system. Proc.Natl.Acad.Sci.USA, 117, 2020
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6M6E
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![BU of 6m6e by Molmil](/molmil-images/mine/6m6e) | |
6M6F
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![BU of 6m6f by Molmil](/molmil-images/mine/6m6f) | |
6MSJ
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![BU of 6msj by Molmil](/molmil-images/mine/6msj) | Cryo-EM structures and dynamics of substrate-engaged human 26S proteasome | Descriptor: | 26S proteasome complex subunit SEM1, 26S proteasome non-ATPase regulatory subunit 1, 26S proteasome non-ATPase regulatory subunit 11, ... | Authors: | Mao, Y.D. | Deposit date: | 2018-10-16 | Release date: | 2018-11-21 | Last modified: | 2019-12-18 | Method: | ELECTRON MICROSCOPY (3.3 Å) | Cite: | Cryo-EM structures and dynamics of substrate-engaged human 26S proteasome. Nature, 565, 2019
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6MSG
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![BU of 6msg by Molmil](/molmil-images/mine/6msg) | Cryo-EM structures and dynamics of substrate-engaged human 26S proteasome | Descriptor: | 26S proteasome complex subunit SEM1, 26S proteasome non-ATPase regulatory subunit 1, 26S proteasome non-ATPase regulatory subunit 11, ... | Authors: | Mao, Y.D. | Deposit date: | 2018-10-16 | Release date: | 2018-11-21 | Last modified: | 2019-12-18 | Method: | ELECTRON MICROSCOPY (3.5 Å) | Cite: | Cryo-EM structures and dynamics of substrate-engaged human 26S proteasome. Nature, 565, 2019
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6MSB
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![BU of 6msb by Molmil](/molmil-images/mine/6msb) | Cryo-EM structures and dynamics of substrate-engaged human 26S proteasome | Descriptor: | 26S proteasome complex subunit SEM1, 26S proteasome non-ATPase regulatory subunit 1, 26S proteasome non-ATPase regulatory subunit 11, ... | Authors: | Mao, Y.D. | Deposit date: | 2018-10-16 | Release date: | 2018-12-05 | Last modified: | 2019-12-18 | Method: | ELECTRON MICROSCOPY (3 Å) | Cite: | Cryo-EM structures and dynamics of substrate-engaged human 26S proteasome. Nature, 565, 2019
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6MSK
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![BU of 6msk by Molmil](/molmil-images/mine/6msk) | Cryo-EM structures and dynamics of substrate-engaged human 26S proteasome | Descriptor: | 26S proteasome complex subunit SEM1, 26S proteasome non-ATPase regulatory subunit 1, 26S proteasome non-ATPase regulatory subunit 11, ... | Authors: | Mao, Y.D. | Deposit date: | 2018-10-16 | Release date: | 2018-11-21 | Last modified: | 2019-12-18 | Method: | ELECTRON MICROSCOPY (3.2 Å) | Cite: | Cryo-EM structures and dynamics of substrate-engaged human 26S proteasome. Nature, 565, 2019
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6MSH
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![BU of 6msh by Molmil](/molmil-images/mine/6msh) | Cryo-EM structures and dynamics of substrate-engaged human 26S proteasome | Descriptor: | 26S proteasome complex subunit SEM1, 26S proteasome non-ATPase regulatory subunit 1, 26S proteasome non-ATPase regulatory subunit 11, ... | Authors: | Mao, Y.D. | Deposit date: | 2018-10-16 | Release date: | 2018-11-21 | Last modified: | 2019-12-18 | Method: | ELECTRON MICROSCOPY (3.6 Å) | Cite: | Cryo-EM structures and dynamics of substrate-engaged human 26S proteasome. Nature, 565, 2019
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7VVE
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![BU of 7vve by Molmil](/molmil-images/mine/7vve) | Complex structure of a leaf-branch compost cutinase variant in complex with mono(2-hydroxyethyl) terephthalic acid | Descriptor: | 2-(2-METHOXYETHOXY)ETHANOL, 4-(2-hydroxyethyloxycarbonyl)benzoic acid, CALCIUM ION, ... | Authors: | Niu, D, Zeng, W, Huang, J.W, Chen, C.C, Liu, W.D, Guo, R.T. | Deposit date: | 2021-11-05 | Release date: | 2022-03-09 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.98 Å) | Cite: | Substrate-Binding Mode of a Thermophilic PET Hydrolase and Engineering the Enzyme to Enhance the Hydrolytic Efficacy. Acs Catalysis, 12, 2022
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7VVC
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![BU of 7vvc by Molmil](/molmil-images/mine/7vvc) | Crystal structure of inactive mutant of leaf-branch compost cutinase variant | Descriptor: | ACETATE ION, ACETIC ACID, CALCIUM ION, ... | Authors: | Niu, D, Zeng, W, Huang, J.W, Chen, C.C, Liu, W.D, Guo, R.T. | Deposit date: | 2021-11-05 | Release date: | 2022-03-09 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.82 Å) | Cite: | Substrate-Binding Mode of a Thermophilic PET Hydrolase and Engineering the Enzyme to Enhance the Hydrolytic Efficacy. Acs Catalysis, 12, 2022
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7BFZ
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![BU of 7bfz by Molmil](/molmil-images/mine/7bfz) | X-ray structure of human prostate-specific membrane antigen(PSMA) in complex with a inhibitor Glu-490 | Descriptor: | (((S)-1-carboxy-5-((E)-2-cyano-3-(5-(1-(3-methoxy-3-oxopropyl)-1,2,3,4-tetrahydroquinolin-6-yl)thiophen-2-yl)acrylamido)pentyl)carbamoyl)-L-glutamic acid, 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... | Authors: | Rakhimbekova, A, Motlova, L, Barinka, C. | Deposit date: | 2021-01-05 | Release date: | 2021-08-18 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (1.73 Å) | Cite: | A prostate-specific membrane antigen activated molecular rotor for real-time fluorescence imaging. Nat Commun, 12, 2021
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6N6B
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![BU of 6n6b by Molmil](/molmil-images/mine/6n6b) | |
6MSD
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![BU of 6msd by Molmil](/molmil-images/mine/6msd) | Cryo-EM structures and dynamics of substrate-engaged human 26S proteasome | Descriptor: | 26S proteasome complex subunit SEM1, 26S proteasome non-ATPase regulatory subunit 1, 26S proteasome non-ATPase regulatory subunit 11, ... | Authors: | Mao, Y.D. | Deposit date: | 2018-10-16 | Release date: | 2018-12-05 | Last modified: | 2019-12-18 | Method: | ELECTRON MICROSCOPY (3.2 Å) | Cite: | Cryo-EM structures and dynamics of substrate-engaged human 26S proteasome. Nature, 565, 2019
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6LKJ
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![BU of 6lkj by Molmil](/molmil-images/mine/6lkj) | Two-component system protein mediate signal transduction | Descriptor: | 6-O-phosphono-beta-D-galactopyranose, ABC transporter, solute-binding protein | Authors: | Wang, M, Tao, Y. | Deposit date: | 2019-12-19 | Release date: | 2020-12-02 | Last modified: | 2024-03-27 | Method: | X-RAY DIFFRACTION (2.004 Å) | Cite: | Interface switch mediates signal transmission in a two-component system. Proc.Natl.Acad.Sci.USA, 117, 2020
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6MSE
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![BU of 6mse by Molmil](/molmil-images/mine/6mse) | Cryo-EM structures and dynamics of substrate-engaged human 26S proteasome | Descriptor: | 26S proteasome complex subunit SEM1, 26S proteasome non-ATPase regulatory subunit 1, 26S proteasome non-ATPase regulatory subunit 11, ... | Authors: | Mao, Y.D. | Deposit date: | 2018-10-16 | Release date: | 2018-11-21 | Last modified: | 2019-12-18 | Method: | ELECTRON MICROSCOPY (3.3 Å) | Cite: | Cryo-EM structures and dynamics of substrate-engaged human 26S proteasome. Nature, 565, 2019
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7XE8
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![BU of 7xe8 by Molmil](/molmil-images/mine/7xe8) | |
8GPD
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![BU of 8gpd by Molmil](/molmil-images/mine/8gpd) | Crystal structure of NDM-1 at pH5.5 (Succinate) in complex with hydrolyzed penicillin V | Descriptor: | (2R,4S)-5,5-dimethyl-2-[(1R)-2-oxidanyl-2-oxidanylidene-1-(2-phenoxyethanoylamino)ethyl]-1,3-thiazolidine-4-carboxylic acid, Metallo beta lactamase NDM-1, POTASSIUM ION, ... | Authors: | Shi, X, Dai, Y, Zhang, Q, Liu, W. | Deposit date: | 2022-08-26 | Release date: | 2023-08-30 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (1.4 Å) | Cite: | Interplay between the beta-lactam side chain and an active-site mobile loop of NDM-1 in penicillin hydrolysis as a potential target for mechanism-based inhibitor design. Int.J.Biol.Macromol., 262, 2024
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