6QLZ
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![BU of 6qlz by Molmil](/molmil-images/mine/6qlz) | IDOL F3ab subdomain | Descriptor: | E3 ubiquitin-protein ligase MYLIP | Authors: | Martinelli, L, Johansson, P, Wan, P.T, Gunnarsson, J, Guo, H, Boyd, H. | Deposit date: | 2019-02-01 | Release date: | 2020-02-19 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (2.343 Å) | Cite: | Structural analysis of the LDL receptor-interacting FERM domain in the E3 ubiquitin ligase IDOL reveals an obscured substrate-binding site. J.Biol.Chem., 295, 2020
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1LV0
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![BU of 1lv0 by Molmil](/molmil-images/mine/1lv0) | Crystal structure of the Rab effector guanine nucleotide dissociation inhibitor (GDI) in complex with a geranylgeranyl (GG) peptide | Descriptor: | GERAN-8-YL GERAN, RAB GDP disossociation inhibitor alpha, SULFATE ION | Authors: | An, Y, Shao, Y, Alory, C, Matteson, J, Sakisaka, T, Chen, W, Gibbs, R.A, Wilson, I.A, Balch, W.E. | Deposit date: | 2002-05-23 | Release date: | 2003-08-05 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Geranylgeranyl switching regulates GDI-Rab GTPase recycling. Structure, 11, 2003
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3UJJ
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![BU of 3ujj by Molmil](/molmil-images/mine/3ujj) | |
4Z97
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![BU of 4z97 by Molmil](/molmil-images/mine/4z97) | |
2LPI
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![BU of 2lpi by Molmil](/molmil-images/mine/2lpi) | NMR structure of a monomeric mutant (A72R) of major ampullate spidroin 1 N-terminal domain | Descriptor: | Major ampullate spidroin 1 | Authors: | Jaudzems, K, Nordling, K, Landreh, M, Rising, A, Askarieh, G, Knight, S.D, Johansson, J. | Deposit date: | 2012-02-14 | Release date: | 2012-06-27 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | pH-Dependent Dimerization of Spider Silk N-Terminal Domain Requires Relocation of a Wedged Tryptophan Side Chain. J.Mol.Biol., 422, 2012
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4FE6
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![BU of 4fe6 by Molmil](/molmil-images/mine/4fe6) | Crystal Structure of HIV-1 Protease in Complex with an enamino-oxindole inhibitor | Descriptor: | (3R,3aS,6aR)-hexahydrofuro[2,3-b]furan-3-yl {(2S,3R)-3-hydroxy-4-[({(3Z)-3-[1-(methylamino)ethylidene]-2-oxo-2,3-dihydro-1H-indol-5-yl}sulfonyl)(2-methylpropyl)amino]-1-phenylbutan-2-yl}carbamate, HIV protease | Authors: | Silva, A.M, Eissenstat, M, Guerassina, T, Gulnik, S, Afonina, E, Yu, B, Erickson, J, Ludke, D, Yokoe, H. | Deposit date: | 2012-05-29 | Release date: | 2012-07-18 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Enamino-oxindole HIV protease inhibitors. Bioorg.Med.Chem.Lett., 22, 2012
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4FBS
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![BU of 4fbs by Molmil](/molmil-images/mine/4fbs) | Structure of monomeric NT from Euprosthenops australis Major Ampullate Spidroin 1 (MaSp1) | Descriptor: | BROMIDE ION, Major ampullate spidroin 1 | Authors: | Askarieh, G, Hedhammar, M, Rising, A, Johansson, J, Knight, S.D. | Deposit date: | 2012-05-23 | Release date: | 2012-08-01 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | pH-Dependent Dimerization of Spider Silk N-Terminal Domain Requires Relocation of a Wedged Tryptophan Side Chain J.Mol.Biol., 2012
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4FHR
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![BU of 4fhr by Molmil](/molmil-images/mine/4fhr) | Crystal structure of the complex between the flagellar motor proteins FliG and FliM. | Descriptor: | Flagellar motor switch protein FliG, Flagellar motor switch protein FliM | Authors: | Paz, A, Vartanian, A.S, Fortgang, E.A, Abramson, J, Dahlquist, F.W. | Deposit date: | 2012-06-06 | Release date: | 2012-08-22 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (1.931 Å) | Cite: | Structure of flagellar motor proteins in complex allows for insights into motor structure and switching. J.Biol.Chem., 287, 2012
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5XOX
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![BU of 5xox by Molmil](/molmil-images/mine/5xox) | Crystal structure of tRNA(His) guanylyltranserase from Saccharomyces cerevisiae | Descriptor: | GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, PHOSPHATE ION, ... | Authors: | Lee, K, Lee, E.H, Son, J, Hwang, K.Y. | Deposit date: | 2017-05-31 | Release date: | 2017-07-12 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Crystal structure of tRNA(His) guanylyltransferase from Saccharomyces cerevisiae Biochem. Biophys. Res. Commun., 490, 2017
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2KZQ
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![BU of 2kzq by Molmil](/molmil-images/mine/2kzq) | s34r Structure | Descriptor: | Envelope glycoprotein E2 peptide | Authors: | Montserret, R, Dubuisson, J, Penin, F. | Deposit date: | 2010-06-21 | Release date: | 2011-03-02 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | Identification of new functional regions in hepatitis C virus envelope glycoprotein E2. J.Virol., 85, 2011
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7CJV
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![BU of 7cjv by Molmil](/molmil-images/mine/7cjv) | Solution structure of monomeric superoxide dismutase 1 with an additional mutation H46W in a dilute environment | Descriptor: | Monomeric Human Cu,Zn Superoxide dismutase | Authors: | Iwakawa, N, Morimoto, D, Walinda, E, Danielsson, J, Shirakawa, M, Sugase, K. | Deposit date: | 2020-07-14 | Release date: | 2021-05-26 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | Transient Diffusive Interactions with a Protein Crowder Affect Aggregation Processes of Superoxide Dismutase 1 beta-Barrel. J.Phys.Chem.B, 125, 2021
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7CJW
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![BU of 7cjw by Molmil](/molmil-images/mine/7cjw) | Solution structure of monomeric superoxide dismutase 1 with an additional mutation H46W in a crowded environment | Descriptor: | Monomeric Human Cu,Zn Superoxide dismutase | Authors: | Iwakawa, N, Morimoto, D, Walinda, E, Danielsson, J, Shirakawa, M, Sugase, K. | Deposit date: | 2020-07-14 | Release date: | 2021-05-26 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | Transient Diffusive Interactions with a Protein Crowder Affect Aggregation Processes of Superoxide Dismutase 1 beta-Barrel. J.Phys.Chem.B, 125, 2021
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5FA9
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![BU of 5fa9 by Molmil](/molmil-images/mine/5fa9) | Bifunctional Methionine Sulfoxide Reductase AB (MsrAB) from Treponema denticola | Descriptor: | (4S,5S)-1,2-DITHIANE-4,5-DIOL, 2,3-DIHYDROXY-1,4-DITHIOBUTANE, Peptide methionine sulfoxide reductase MsrA | Authors: | Han, A, Son, J, Kim, H.-Y, Hwang, K.Y. | Deposit date: | 2015-12-11 | Release date: | 2016-09-14 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.302 Å) | Cite: | Essential Role of the Linker Region in the Higher Catalytic Efficiency of a Bifunctional MsrA-MsrB Fusion Protein Biochemistry, 55, 2016
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7LCM
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![BU of 7lcm by Molmil](/molmil-images/mine/7lcm) | Receiver Domain of RssB bound to beryllofluoride | Descriptor: | BERYLLIUM TRIFLUORIDE ION, MAGNESIUM ION, Regulator of RpoS | Authors: | Deaconescu, A.M, Schwartz, J, Son, J. | Deposit date: | 2021-01-11 | Release date: | 2021-04-07 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (1.91 Å) | Cite: | Phospho-dependent signaling during the general stress response by the atypical response regulator and ClpXP adaptor RssB. Protein Sci., 30, 2021
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7L9C
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![BU of 7l9c by Molmil](/molmil-images/mine/7l9c) | Receiver Domain of RssB | Descriptor: | Regulator of RpoS | Authors: | Deaconescu, A.M, Son, J, Schwartz, J. | Deposit date: | 2021-01-03 | Release date: | 2021-04-07 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (1.85 Å) | Cite: | Phospho-dependent signaling during the general stress response by the atypical response regulator and ClpXP adaptor RssB. Protein Sci., 30, 2021
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4UQ6
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![BU of 4uq6 by Molmil](/molmil-images/mine/4uq6) | Electron density map of GluA2em in complex with LY451646 and glutamate | Descriptor: | GLUTAMATE RECEPTOR 2, GLUTAMIC ACID | Authors: | Meyerson, J.R, Kumar, J, Chittori, S, Rao, P, Pierson, J, Bartesaghi, A, Mayer, M.L, Subramaniam, S. | Deposit date: | 2014-06-20 | Release date: | 2014-08-13 | Last modified: | 2017-08-02 | Method: | ELECTRON MICROSCOPY (12.8 Å) | Cite: | Structural Mechanism of Glutamate Receptor Activation and Desensitization Nature, 514, 2014
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4UQQ
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![BU of 4uqq by Molmil](/molmil-images/mine/4uqq) | Electron density map of GluK2 desensitized state in complex with 2S,4R-4-methylglutamate | Descriptor: | GLUTAMATE RECEPTOR IONOTROPIC, KAINATE 2, GLUTAMIC ACID | Authors: | Meyerson, J.R, Kumar, J, Chittori, S, Rao, P, Pierson, J, Bartesaghi, A, Mayer, M.L, Subramaniam, S. | Deposit date: | 2014-06-24 | Release date: | 2014-08-13 | Last modified: | 2017-08-02 | Method: | ELECTRON MICROSCOPY (7.6 Å) | Cite: | Structural Mechanism of Glutamate Receptor Activation and Desensitization Nature, 514, 2014
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4UQJ
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![BU of 4uqj by Molmil](/molmil-images/mine/4uqj) | Cryo-EM density map of GluA2em in complex with ZK200775 | Descriptor: | GLUTAMATE RECEPTOR 2, {[7-morpholin-4-yl-2,3-dioxo-6-(trifluoromethyl)-3,4-dihydroquinoxalin-1(2H)-yl]methyl}phosphonic acid | Authors: | Meyerson, J.R, Kumar, J, Chittori, S, Rao, P, Pierson, J, Bartesaghi, A, Mayer, M.L, Subramaniam, S. | Deposit date: | 2014-06-24 | Release date: | 2014-08-13 | Last modified: | 2017-08-02 | Method: | ELECTRON MICROSCOPY (10.4 Å) | Cite: | Structural Mechanism of Glutamate Receptor Activation and Desensitization Nature, 514, 2014
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4UQK
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![BU of 4uqk by Molmil](/molmil-images/mine/4uqk) | Electron density map of GluA2em in complex with quisqualate and LY451646 | Descriptor: | (S)-2-AMINO-3-(3,5-DIOXO-[1,2,4]OXADIAZOLIDIN-2-YL)-PROPIONIC ACID, GLUTAMATE RECEPTOR 2 | Authors: | Meyerson, J.R, Kumar, J, Chittori, S, Rao, P, Pierson, J, Bartesaghi, A, Mayer, M.L, Subramaniam, S. | Deposit date: | 2014-06-24 | Release date: | 2014-08-13 | Last modified: | 2017-08-02 | Method: | ELECTRON MICROSCOPY (16.4 Å) | Cite: | Structural Mechanism of Glutamate Receptor Activation and Desensitization Nature, 514, 2014
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7E3Q
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7E3S
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7E3T
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7E3R
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![BU of 7e3r by Molmil](/molmil-images/mine/7e3r) | Crystal structure of TrmL from Vibrio vulnificus | Descriptor: | tRNA (cytidine(34)-2'-O)-methyltransferase | Authors: | Kim, J, Son, J. | Deposit date: | 2021-02-09 | Release date: | 2022-02-16 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.79 Å) | Cite: | Crystal structure of tRNA mehtyltransferase TrmL from Vibrio vulnificus To be published
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6Y8K
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![BU of 6y8k by Molmil](/molmil-images/mine/6y8k) | Crystal structure of CD137 in complex with the cyclic peptide BCY10916 | Descriptor: | 1,1',1''-(1,3,5-triazinane-1,3,5-triyl)tripropan-1-one, 1,2-ETHANEDIOL, ACETATE ION, ... | Authors: | Upadhyaya, P, Kublin, J, Dods, R, Kristensson, J, Lahdenranta, J, Kleyman, M, Repash, E, Ma, J, Mudd, G, Van Rietschoten, K, Haines, E, Harrison, H, Beswick, P, Chen, L, McDonnell, K, Battula, S, Hurov, K, Keen, N. | Deposit date: | 2020-03-05 | Release date: | 2021-02-03 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (2.011 Å) | Cite: | Anticancer immunity induced by a synthetic tumor-targeted CD137 agonist. J Immunother Cancer, 9, 2021
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6QGK
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![BU of 6qgk by Molmil](/molmil-images/mine/6qgk) | Structure of human Bcl-2 in complex with THIQ-phenyl pyrazole compound | Descriptor: | 1-[2-[[(3~{S})-3-(aminomethyl)-3,4-dihydro-1~{H}-isoquinolin-2-yl]carbonyl]phenyl]-~{N},~{N}-dibutyl-5-methyl-pyrazole-3-carboxamide, ACETATE ION, Apoptosis regulator Bcl-2,Bcl-2-like protein 1,Apoptosis regulator Bcl-2,Bcl-2-like protein 1 | Authors: | Dokurno, P, Murray, J, Davidson, J, Chen, I, Davis, B, Graham, C.J, Harris, R, Jordan, A.M, Matassova, N, Pedder, C, Ray, S, Roughley, S, Smith, J, Walmsley, C, Wang, Y, Whitehead, N, Williamson, D.S, Casara, P, Le Diguarher, T, Hickman, J, Stark, J, Kotschy, A, Geneste, O, Hubbard, R.E. | Deposit date: | 2019-01-11 | Release date: | 2019-06-12 | Last modified: | 2024-05-15 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Establishing Drug Discovery and Identification of Hit Series for the Anti-apoptotic Proteins, Bcl-2 and Mcl-1. Acs Omega, 4, 2019
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