6UTL
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6utl by Molmil](/molmil-images/mine/6utl) | Yeast Thiol Specific antoxidant 2 with C171S mutation and catalytic cysteine alkylated with iodoacetamide | Descriptor: | Peroxiredoxin TSA2 | Authors: | Tairum, C.A, Bannitz-Fernandes, R, Tonoli, C.C.C, Murakami, M.T, de Oliveira, M.A, Netto, L.E.S. | Deposit date: | 2019-10-29 | Release date: | 2020-07-15 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Reduction of sulfenic acids by ascorbate in proteins, connecting thiol-dependent to alternative redox pathways. Free Radic Biol Med, 156, 2020
|
|
6MZT
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6mzt by Molmil](/molmil-images/mine/6mzt) | Solution structure of alpha-KTx-6.21 (UroTx) from Urodacus yaschenkoi | Descriptor: | Potassium channel toxin alpha-KTx 6.21 | Authors: | Chin, Y.K.-Y, Luna-Ramirez, K, Anangi, R, King, G.F. | Deposit date: | 2018-11-05 | Release date: | 2020-03-11 | Last modified: | 2023-06-14 | Method: | SOLUTION NMR | Cite: | Structural basis of the potency and selectivity of Urotoxin, a potent Kv1 blocker from scorpion venom. Biochem. Pharmacol., 174, 2020
|
|
6IFV
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6ifv by Molmil](/molmil-images/mine/6ifv) | C-terminal truncated KsgA from Bacillus subtilis 168 | Descriptor: | Ribosomal RNA small subunit methyltransferase A | Authors: | Bhujbalrao, R, Anand, R. | Deposit date: | 2018-09-21 | Release date: | 2019-01-30 | Last modified: | 2024-03-27 | Method: | X-RAY DIFFRACTION (3.11 Å) | Cite: | Deciphering Determinants in Ribosomal Methyltransferases That Confer Antimicrobial Resistance. J. Am. Chem. Soc., 141, 2019
|
|
6IFT
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6ift by Molmil](/molmil-images/mine/6ift) | KsgA from Bacillus subtilis in complex with SAM | Descriptor: | Ribosomal RNA small subunit methyltransferase A, S-ADENOSYLMETHIONINE | Authors: | Bhujbalrao, R, Anand, R. | Deposit date: | 2018-09-21 | Release date: | 2019-01-30 | Last modified: | 2024-03-27 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Deciphering Determinants in Ribosomal Methyltransferases That Confer Antimicrobial Resistance. J. Am. Chem. Soc., 141, 2019
|
|
6IFW
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6ifw by Molmil](/molmil-images/mine/6ifw) | |
6Y3D
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6y3d by Molmil](/molmil-images/mine/6y3d) | X-ray structure of thermophilic C-phycocyanin from Galdiera phlegrea | Descriptor: | ACETATE ION, C-phycocyanin alpha chain, C-phycocyanin beta chain, ... | Authors: | Ferraro, G, Lucignano, R, Marseglia, A, Merlino, A. | Deposit date: | 2020-02-18 | Release date: | 2020-12-30 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | X-ray structure of C-phycocyanin from Galdieria phlegrea: Determinants of thermostability and comparison with a C-phycocyanin in the entire phycobilisome. Biochim Biophys Acta Bioenerg, 1861, 2020
|
|
3IPS
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3ips by Molmil](/molmil-images/mine/3ips) | X-ray structure of benzisoxazole synthetic agonist bound to the LXR-alpha | Descriptor: | Nuclear receptor coactivator 1, Oxysterols receptor LXR-alpha, SULFATE ION, ... | Authors: | Fradera, X, Vu, D, Nimz, O, Skene, R, Hosfield, D, Wijnands, R, Cooke, A.J, Haunso, A, King, A, Bennet, D.J, McGuire, R, Uitdehaag, J.C.M. | Deposit date: | 2009-08-18 | Release date: | 2010-06-02 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (2.26 Å) | Cite: | X-ray structures of the LXRalpha LBD in its homodimeric form and implications for heterodimer signaling. J.Mol.Biol., 399, 2010
|
|
3M7Q
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3m7q by Molmil](/molmil-images/mine/3m7q) | Crystal structure of recombinant Kunitz Type serine protease Inhibitor-1 from the Caribbean sea anemone stichodactyla helianthus in complex with bovine pancreatic trypsin | Descriptor: | Cationic trypsin, Kunitz-type proteinase inhibitor SHPI-1, PHOSPHATE ION | Authors: | Garcia-Fernandez, R, Redecke, L, Pons, T, Perbandt, M, Gil, D, Talavera, A, Gonzalez, Y, de los angeles Chavez, M, Betzel, C. | Deposit date: | 2010-03-17 | Release date: | 2011-03-16 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Structural insights into serine protease inhibition by a marine invertebrate BPTI Kunitz-type inhibitor. J.Struct.Biol., 180, 2012
|
|
3IPU
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3ipu by Molmil](/molmil-images/mine/3ipu) | X-ray structure of benzisoxazole urea synthetic agonist bound to the LXR-alpha | Descriptor: | 4-{[methyl(3-{[7-propyl-3-(trifluoromethyl)-1,2-benzisoxazol-6-yl]oxy}propyl)carbamoyl]amino}benzoic acid, Nuclear receptor coactivator 1, Oxysterols receptor LXR-alpha, ... | Authors: | Fradera, X, Vu, D, Nimz, O, Skene, R, Hosfield, D, Wijnands, R, Cooke, A.J, Haunso, A, King, A, Bennet, D.J, McGuire, R, Uitdehaag, J.C.M. | Deposit date: | 2009-08-18 | Release date: | 2010-06-02 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | X-ray structures of the LXRalpha LBD in its homodimeric form and implications for heterodimer signaling. J.Mol.Biol., 399, 2010
|
|
3IPQ
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3ipq by Molmil](/molmil-images/mine/3ipq) | X-ray structure of GW3965 synthetic agonist bound to the LXR-alpha | Descriptor: | Nuclear receptor coactivator 1, Oxysterols receptor LXR-alpha, SULFATE ION, ... | Authors: | Fradera, X, Vu, D, Nimz, O, Skene, R, Hosfield, D, Wijnands, R, Cooke, A.J, Haunso, A, King, A, Bennet, D.J, McGuire, R, Uitdehaag, J.C.M. | Deposit date: | 2009-08-18 | Release date: | 2010-06-02 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | X-ray structures of the LXRalpha LBD in its homodimeric form and implications for heterodimer signaling. J.Mol.Biol., 399, 2010
|
|
5XKQ
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5xkq by Molmil](/molmil-images/mine/5xkq) | Crystal structure of Msmeg3575 in complex with ammeline | Descriptor: | 4,6-diamino-1,3,5-triazin-2-ol, ACETATE ION, CMP/dCMP deaminase, ... | Authors: | Gaded, V.M, Anand, R. | Deposit date: | 2017-05-09 | Release date: | 2017-08-09 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Selective Deamination of Mutagens by a Mycobacterial Enzyme J. Am. Chem. Soc., 139, 2017
|
|
5XKO
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5xko by Molmil](/molmil-images/mine/5xko) | |
5XKP
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5xkp by Molmil](/molmil-images/mine/5xkp) | Crystal structure of Msmeg3575 in complex with 5-azacytosine | Descriptor: | 6-amino-1,3,5-triazin-2(1H)-one, ACETATE ION, CMP/dCMP deaminase, ... | Authors: | Gaded, V.M, Anand, R. | Deposit date: | 2017-05-08 | Release date: | 2017-08-09 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Selective Deamination of Mutagens by a Mycobacterial Enzyme J. Am. Chem. Soc., 139, 2017
|
|
5XAZ
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5xaz by Molmil](/molmil-images/mine/5xaz) | |
5XKR
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5xkr by Molmil](/molmil-images/mine/5xkr) | Crystal structure of Msmeg3575 in complex with benzoguanamine | Descriptor: | 6-phenyl-1,3,5-triazine-2,4-diamine, ACETATE ION, CMP/dCMP deaminase, ... | Authors: | Gaded, V.M, Anand, R. | Deposit date: | 2017-05-09 | Release date: | 2017-08-09 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (1.38 Å) | Cite: | Selective Deamination of Mutagens by a Mycobacterial Enzyme J. Am. Chem. Soc., 139, 2017
|
|
5XAY
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5xay by Molmil](/molmil-images/mine/5xay) | |
5E7V
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5e7v by Molmil](/molmil-images/mine/5e7v) | Potent Vitamin D Receptor Agonist | Descriptor: | 1-ALPHA-HYDROXY-27-NOR-25-O-CARBONYL-VITAMIN D3, Nuclear receptor coactivator 1, Vitamin D3 receptor A | Authors: | Otero, R, Seoane, S, Sigueiro, R, Belorusova, A.Y, Maestro, M.A, Perez-Fernandez, R, Rochel, N, Mourino, A. | Deposit date: | 2015-10-13 | Release date: | 2015-11-25 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Carborane-based design of a potent vitamin D receptor agonist. Chem Sci, 7, 2016
|
|
5ZRN
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5zrn by Molmil](/molmil-images/mine/5zrn) | |
3OFW
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3ofw by Molmil](/molmil-images/mine/3ofw) | Crystal structure of recombinant Kunitz Type serine protease Inhibitor-1 from the Carribean sea anemone stichodactyla helianthus | Descriptor: | CHLORIDE ION, Kunitz-type proteinase inhibitor SHPI-1 | Authors: | Garcia-Fernandez, R, Redecke, L, Pons, T, Perbandt, M, Talavera, A, Gil, D, Gonzalez, Y, de los Angeles Chavez, M, Betzel, C. | Deposit date: | 2010-08-16 | Release date: | 2011-08-17 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Structure of the recombinant BPTI/Kunitz-type inhibitor rShPI-1A from the marine invertebrate Stichodactyla helianthus. Acta Crystallogr.,Sect.F, 68, 2012
|
|
5H4E
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5h4e by Molmil](/molmil-images/mine/5h4e) | |
6JT9
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6jt9 by Molmil](/molmil-images/mine/6jt9) | Crystal Structure of D464A mutant of FGAM Synthetase | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, CHLORIDE ION, GLYCEROL, ... | Authors: | Sharma, N, Ahalawat, N, Sandhu, P, Mondal, J, Anand, R. | Deposit date: | 2019-04-10 | Release date: | 2020-03-04 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Role of allosteric switches and adaptor domains in long-distance cross-talk and transient tunnel formation. Sci Adv, 6, 2020
|
|
5HT9
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5ht9 by Molmil](/molmil-images/mine/5ht9) | |
7C3T
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7c3t by Molmil](/molmil-images/mine/7c3t) | Crystal structure of NE0047 (N66Q) mutant in complex with 8-azaguanine | Descriptor: | 5-AMINO-1H-[1,2,3]TRIAZOLO[4,5-D]PYRIMIDIN-7-OL, Cytidine and deoxycytidylate deaminase zinc-binding region, ZINC ION | Authors: | Gaded, V, Bitra, A, Singh, J, Anand, R. | Deposit date: | 2020-05-14 | Release date: | 2021-05-26 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.07 Å) | Cite: | Structure guided mutagenesis reveals the substrate determinants of guanine deaminase. J.Struct.Biol., 213, 2021
|
|
6JT8
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6jt8 by Molmil](/molmil-images/mine/6jt8) | Crystal structure of 450-451_deletion mutant of FGAM Synthetase | Descriptor: | 1,2-ETHANEDIOL, ADENOSINE-5'-DIPHOSPHATE, GLYCEROL, ... | Authors: | Sharma, N, Ahalawat, N, Sandhu, P, Mondal, J, Anand, R. | Deposit date: | 2019-04-10 | Release date: | 2020-03-04 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Role of allosteric switches and adaptor domains in long-distance cross-talk and transient tunnel formation. Sci Adv, 6, 2020
|
|
7C3U
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7c3u by Molmil](/molmil-images/mine/7c3u) | Crystal structure of NE0047 (N66A) mutant in complex with 8-azaguanine | Descriptor: | 1,2-ETHANEDIOL, 5-AMINO-1H-[1,2,3]TRIAZOLO[4,5-D]PYRIMIDIN-7-OL, Cytidine and deoxycytidylate deaminase zinc-binding region, ... | Authors: | Gaded, V, Bitra, A, Singh, J, Anand, R. | Deposit date: | 2020-05-14 | Release date: | 2021-05-26 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.86 Å) | Cite: | Structure guided mutagenesis reveals the substrate determinants of guanine deaminase. J.Struct.Biol., 213, 2021
|
|