3M7Q
Crystal structure of recombinant Kunitz Type serine protease Inhibitor-1 from the Caribbean sea anemone stichodactyla helianthus in complex with bovine pancreatic trypsin
Summary for 3M7Q
Entry DOI | 10.2210/pdb3m7q/pdb |
Descriptor | Cationic trypsin, Kunitz-type proteinase inhibitor SHPI-1, PHOSPHATE ION, ... (4 entities in total) |
Functional Keywords | trypsin-inhibitor complex, kunitz-type serine-protease inhibitor, digestion, disulfide bond, hydrolase, metal-binding, protease, secreted, serine protease, zymogen, nematocyst, protease inhibitor, serine protease inhibitor, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor |
Biological source | Stichodactyla helianthus (Carribean sea anemone) More |
Cellular location | Secreted, extracellular space: P00760 Secreted: P31713 |
Total number of polymer chains | 2 |
Total formula weight | 30114.84 |
Authors | Garcia-Fernandez, R.,Redecke, L.,Pons, T.,Perbandt, M.,Gil, D.,Talavera, A.,Gonzalez, Y.,de los angeles Chavez, M.,Betzel, C. (deposition date: 2010-03-17, release date: 2011-03-16, Last modification date: 2023-09-06) |
Primary citation | Garcia-Fernandez, R.,Pons, T.,Perbandt, M.,Valiente, P.A.,Talavera, A.,Gonzalez-Gonzalez, Y.,Rehders, D.,Chavez, M.A.,Betzel, C.,Redecke, L. Structural insights into serine protease inhibition by a marine invertebrate BPTI Kunitz-type inhibitor. J.Struct.Biol., 180:271-279, 2012 Cited by PubMed: 22975140DOI: 10.1016/j.jsb.2012.08.009 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.7 Å) |
Structure validation
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