7A5Y
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![BU of 7a5y by Molmil](/molmil-images/mine/7a5y) | Crystal structure of tetrameric human H215A-SAMHD1 (residues 109-626) with Rp-dGTP-alphaS (T8T) and Mg | Descriptor: | 2'-deoxyguanosine-5'-O-(1-thiotriphosphate), Deoxynucleoside triphosphate triphosphohydrolase SAMHD1, FE (III) ION, ... | Authors: | Morris, E.R, Kunzelmann, S, Caswell, S.J, Purkiss, A, Taylor, I.A. | Deposit date: | 2020-08-24 | Release date: | 2021-05-26 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (2.29 Å) | Cite: | Probing the Catalytic Mechanism and Inhibition of SAMHD1 Using the Differential Properties of R p - and S p -dNTP alpha S Diastereomers. Biochemistry, 60, 2021
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2JNR
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![BU of 2jnr by Molmil](/molmil-images/mine/2jnr) | Discovery and optimization of a natural HIV-1 entry inhibitor targeting the gp41 fusion peptide | Descriptor: | ENV polyprotein, VIR165 | Authors: | Munch, J, Standker, L, Adermann, K, Schulz, A, Pohlmann, S, Chaipan, C, Biet, T, Peters, T, Meyer, B, Wilhelm, D, Lu, H, Jing, W, Jiang, S, Forssmann, W, Kirchhoff, F. | Deposit date: | 2007-02-01 | Release date: | 2007-05-08 | Last modified: | 2023-12-20 | Method: | SOLUTION NMR | Cite: | Discovery and Optimization of a Natural HIV-1 Entry Inhibitor Targeting the gp41 Fusion Peptide. Cell(Cambridge,Mass.), 129, 2007
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1PVW
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![BU of 1pvw by Molmil](/molmil-images/mine/1pvw) | 3,4-dihydroxy-2-butanone 4-phosphate synthase from M. jannaschii | Descriptor: | 3,4-dihydroxy-2-butanone 4-phosphate synthase, CALCIUM ION, PHOSPHATE ION, ... | Authors: | Steinbacher, S, Schiffmann, S, Richter, G, Huber, R, Bacher, A, Fischer, M. | Deposit date: | 2003-06-29 | Release date: | 2003-11-04 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (2.45 Å) | Cite: | Structure of 3,4-Dihydroxy-2-butanone 4-Phosphate Synthase from Methanococcus jannaschii in
Complex with Divalent Metal Ions and the Substrate Ribulose 5-Phosphate: IMPLICATIONS FOR THE
CATALYTIC MECHANISM J.Biol.Chem., 278, 2003
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1PVY
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![BU of 1pvy by Molmil](/molmil-images/mine/1pvy) | 3,4-dihydroxy-2-butanone 4-phosphate synthase from M. jannaschii in complex with ribulose 5-phosphate | Descriptor: | 3,4-dihydroxy-2-butanone 4-phosphate synthase, CALCIUM ION, RIBULOSE-5-PHOSPHATE, ... | Authors: | Steinbacher, S, Schiffmann, S, Richter, G, Huber, R, Bacher, A, Fischer, M. | Deposit date: | 2003-06-29 | Release date: | 2003-11-04 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Structure of 3,4-Dihydroxy-2-butanone 4-Phosphate Synthase from Methanococcus jannaschii in
Complex with Divalent Metal Ions and the Substrate Ribulose 5-Phosphate: IMPLICATIONS FOR THE
CATALYTIC MECHANISM J.Biol.Chem., 278, 2003
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1SNN
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![BU of 1snn by Molmil](/molmil-images/mine/1snn) | 3,4-dihydroxy-2-butanone 4-phosphate synthase from Methanococcus jannaschii | Descriptor: | 3,4-dihydroxy-2-butanone 4-phosphate synthase, CALCIUM ION, RIBULOSE-5-PHOSPHATE, ... | Authors: | Steinbacher, S, Schiffmann, S, Huber, R, Bacher, A, Fischer, M. | Deposit date: | 2004-03-11 | Release date: | 2004-07-20 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (1.55 Å) | Cite: | Metal sites in 3,4-dihydroxy-2-butanone 4-phosphate synthase from Methanococcus jannaschii in complex with the substrate ribulose 5-phosphate. Acta Crystallogr.,Sect.D, 60, 2004
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4ZPP
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![BU of 4zpp by Molmil](/molmil-images/mine/4zpp) | Crystal Structure of Protocadherin Gamma C5 EC1-3 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, MCG133388, ... | Authors: | Wolcott, H.N, Goodman, K.M, Bahna, F, Mannepalli, S, Shapiro, L. | Deposit date: | 2015-05-08 | Release date: | 2015-10-28 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (3.002 Å) | Cite: | Molecular Logic of Neuronal Self-Recognition through Protocadherin Domain Interactions. Cell, 163, 2015
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3LIZ
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![BU of 3liz by Molmil](/molmil-images/mine/3liz) | crystal structure of bla g 2 complexed with Fab 4C3 | Descriptor: | 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, 4C3 monoclonal antibody Heavy Chain, ... | Authors: | Li, M, Gustchina, A, Glesner, J, Wunschmann, S, Pomes, A, Wlodawer, A. | Deposit date: | 2010-01-25 | Release date: | 2010-12-15 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Mechanisms of allergen-antibody interaction of cockroach allergen Bla g 2 with monoclonal antibodies that inhibit IgE antibody binding. Plos One, 6, 2011
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1H7V
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![BU of 1h7v by Molmil](/molmil-images/mine/1h7v) | Rubredoxin from Guillardia Theta | Descriptor: | RUBREDOXIN, ZINC ION | Authors: | Schweimer, K, Hoffmann, S, Wastl, J, Maier, U.G, Roesch, P, Sticht, H. | Deposit date: | 2001-01-16 | Release date: | 2002-01-29 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | Solution structure of a zinc substituted eukaryotic rubredoxin from the cryptomonad alga Guillardia theta. Protein Sci., 9, 2000
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1H92
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![BU of 1h92 by Molmil](/molmil-images/mine/1h92) | SH3 domain of human Lck tyrosine kinase | Descriptor: | PROTO-ONCOGENE TYROSINE-PROTEIN KINASE LCK | Authors: | Schweimer, K, Hoffmann, S, Friedrich, U, Biesinger, B, Roesch, P, Sticht, H. | Deposit date: | 2001-02-22 | Release date: | 2001-10-22 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | Structural Investigation of the Binding of a Herpesviral Protein to the SH3 Domain of Tyrosine Kinase Lck Biochemistry, 41, 2002
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1JHF
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![BU of 1jhf by Molmil](/molmil-images/mine/1jhf) | LEXA G85D MUTANT | Descriptor: | LEXA REPRESSOR, SULFATE ION | Authors: | Luo, Y, Pfuetzner, R.A, Mosimann, S, Little, J.W, Strynadka, N.C.J. | Deposit date: | 2001-06-27 | Release date: | 2001-09-19 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Crystal structure of LexA: a conformational switch for regulation of self-cleavage. Cell(Cambridge,Mass.), 106, 2001
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1JS5
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![BU of 1js5 by Molmil](/molmil-images/mine/1js5) | Solution Structure of dAAUAA DNA Bulge | Descriptor: | 5'-D(*CP*GP*TP*AP*GP*CP*CP*GP*AP*TP*GP*C)-3', 5'-D(*GP*CP*AP*TP*CP*GP*AP*AP*UP*AP*AP*GP*CP*TP*AP*CP*G)-3' | Authors: | Gollmick, F.A, Lorenz, M, Dornberger, U, von Langen, J, Diekmann, S, Fritzsche, H. | Deposit date: | 2001-08-16 | Release date: | 2002-08-28 | Last modified: | 2024-05-22 | Method: | SOLUTION NMR | Cite: | Solution structure of dAATAA and dAAUAA DNA bulges. Nucleic Acids Res., 30, 2002
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6GF2
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![BU of 6gf2 by Molmil](/molmil-images/mine/6gf2) | The structure of the ubiquitin-like modifier FAT10 reveals a novel targeting mechanism for degradation by the 26S proteasome | Descriptor: | Ubiquitin D | Authors: | Aichem, A, Anders, S, Catone, N, Roessler, P, Stotz, S, Berg, A, Schwab, R, Scheuermann, S, Bialas, J, Schmidtke, G, Peter, C, Groettrup, M, Wiesner, S. | Deposit date: | 2018-04-29 | Release date: | 2018-08-08 | Last modified: | 2024-06-19 | Method: | SOLUTION NMR | Cite: | The structure of the ubiquitin-like modifier FAT10 reveals an alternative targeting mechanism for proteasomal degradation. Nat Commun, 9, 2018
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1JRW
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![BU of 1jrw by Molmil](/molmil-images/mine/1jrw) | Solution Structure of dAATAA DNA Bulge | Descriptor: | 5'-D(*CP*GP*TP*AP*GP*CP*CP*GP*AP*TP*GP*C)-3', 5'-D(*GP*CP*AP*TP*CP*GP*AP*AP*TP*AP*AP*GP*CP*TP*AP*CP*G)-3' | Authors: | Gollmick, F.A, Lorenz, M, Dornberger, U, von Langen, J, Diekmann, S, Fritzsche, H. | Deposit date: | 2001-08-15 | Release date: | 2002-08-28 | Last modified: | 2024-05-22 | Method: | SOLUTION NMR | Cite: | Solution structure of dAATAA and dAAUAA DNA bulges. Nucleic Acids Res., 30, 2002
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1JRV
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![BU of 1jrv by Molmil](/molmil-images/mine/1jrv) | SOLUTION STRUCTURE OF DAATAA DNA BULGE | Descriptor: | 5'-D(*CP*GP*TP*AP*GP*CP*CP*GP*AP*TP*GP*C)-3', 5'-D(*GP*CP*AP*TP*CP*GP*AP*AP*TP*AP*AP*GP*CP*TP*AP*CP*G)-3' | Authors: | Gollmick, F.A, Lorenz, M, Dornberger, U, von Langen, J, Diekmann, S, Fritzsche, H. | Deposit date: | 2001-08-15 | Release date: | 2002-06-19 | Last modified: | 2024-05-22 | Method: | SOLUTION NMR | Cite: | Solution structure of dAATAA and dAAUAA DNA bulges. Nucleic Acids Res., 30, 2002
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1JS7
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![BU of 1js7 by Molmil](/molmil-images/mine/1js7) | Solution Structure of dAAUAA DNA Bulge | Descriptor: | 5'-D(*CP*GP*TP*AP*GP*CP*CP*GP*AP*TP*GP*C)-3', 5'-D(*GP*CP*AP*TP*CP*GP*AP*AP*UP*AP*AP*GP*CP*TP*AP*CP*G)-3' | Authors: | Gollmick, F.A, Lorenz, M, Dornberger, U, von Langen, J, Diekmann, S, Fritzsche, H. | Deposit date: | 2001-08-16 | Release date: | 2002-06-19 | Last modified: | 2024-05-22 | Method: | SOLUTION NMR | Cite: | Solution structure of dAATAA and dAAUAA DNA bulges. Nucleic Acids Res., 30, 2002
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1JHH
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![BU of 1jhh by Molmil](/molmil-images/mine/1jhh) | LEXA S119A MUTANT | Descriptor: | LEXA REPRESSOR, SULFATE ION | Authors: | Luo, Y, Pfuetzner, R.A, Mosimann, S, Little, J.W, Strynadka, N.C.J. | Deposit date: | 2001-06-27 | Release date: | 2001-09-19 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Crystal structure of LexA: a conformational switch for regulation of self-cleavage. Cell(Cambridge,Mass.), 106, 2001
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1JHC
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![BU of 1jhc by Molmil](/molmil-images/mine/1jhc) | LEXA S119A C-TERMINAL TRYPTIC FRAGMENT | Descriptor: | LEXA REPRESSOR | Authors: | Luo, Y, Pfuetzner, R.A, Mosimann, S, Little, J.W, Strynadka, N.C.J. | Deposit date: | 2001-06-27 | Release date: | 2001-09-19 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Crystal structure of LexA: a conformational switch for regulation of self-cleavage. Cell(Cambridge,Mass.), 106, 2001
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1JHE
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![BU of 1jhe by Molmil](/molmil-images/mine/1jhe) | LEXA L89P Q92W E152A K156A MUTANT | Descriptor: | LEXA REPRESSOR | Authors: | Luo, Y, Pfuetzner, R.A, Mosimann, S, Little, J.W, J Strynadka, N.C. | Deposit date: | 2001-06-27 | Release date: | 2001-09-19 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Crystal structure of LexA: a conformational switch for regulation of self-cleavage. Cell(Cambridge,Mass.), 106, 2001
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1M22
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![BU of 1m22 by Molmil](/molmil-images/mine/1m22) | X-ray structure of native peptide amidase from Stenotrophomonas maltophilia at 1.4 A | Descriptor: | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, peptide amidase | Authors: | Labahn, J, Neumann, S, Buldt, G, Kula, M.-R, Granzin, J. | Deposit date: | 2002-06-21 | Release date: | 2002-10-16 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (1.4 Å) | Cite: | An alternative mechanism for amidase signature enzymes J.MOL.BIOL., 322, 2002
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1M21
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![BU of 1m21 by Molmil](/molmil-images/mine/1m21) | Crystal structure analysis of the peptide amidase PAM in complex with the competitive inhibitor chymostatin | Descriptor: | CHYMOSTATIN, Peptide Amidase | Authors: | Labahn, J, Neumann, S, Buldt, G, Kula, M.-R, Granzin, J. | Deposit date: | 2002-06-21 | Release date: | 2002-10-16 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | An alternative mechanism for amidase signature enzymes J.MOL.BIOL., 322, 2002
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3LOS
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![BU of 3los by Molmil](/molmil-images/mine/3los) | Atomic Model of Mm-cpn in the Closed State | Descriptor: | Chaperonin | Authors: | Zhang, J, Baker, M.L, Schroeder, G, Douglas, N.R, Reissmann, S, Jakana, J, Dougherty, M, Fu, C.J, Levitt, M, Ludtke, S.J, Frydman, J, Chiu, W. | Deposit date: | 2010-02-04 | Release date: | 2010-03-16 | Last modified: | 2018-07-18 | Method: | ELECTRON MICROSCOPY (4.3 Å) | Cite: | Mechanism of folding chamber closure in a group II chaperonin Nature, 463, 2010
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5BMF
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![BU of 5bmf by Molmil](/molmil-images/mine/5bmf) | Crystal Structure of a Theophylline binding antibody Fab fragment | Descriptor: | 2-(5-{1-[1-(1,3-dimethyl-2,6-dioxo-2,3,6,7-tetrahydro-1H-purin-8-yl)-4,15-dioxo-8,11-dioxa-5,14-diazaicosan-20-yl]-3,3-dimethyl-6-sulfo-1,3-dihydro-2H-indol-2-ylidene}penta-1,3-dien-1-yl)-1-ethyl-3,3-dimethyl-3H-indolium-5-sulfonate, Fab fragment heavy chain, Fab fragment light chain | Authors: | Bujotzek, A, Fuchs, A, Changtao, Q, Klostermann, S, Benz, J, Antes, I, Dengl, S, Hoffmann, E, Georges, G. | Deposit date: | 2015-05-22 | Release date: | 2015-07-29 | Last modified: | 2024-05-01 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | MoFvAb: Modeling the Fv region of antibodies. Mabs, 7, 2015
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1W1F
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![BU of 1w1f by Molmil](/molmil-images/mine/1w1f) | SH3 DOMAIN OF HUMAN LYN TYROSINE KINASE | Descriptor: | TYROSINE-PROTEIN KINASE LYN | Authors: | Bauer, F, Schweimer, K, Hoffmann, S, Roesch, P, Sticht, H. | Deposit date: | 2004-06-17 | Release date: | 2005-07-06 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | Structural Characterization of Lyn-SH3 Domain in Complex with a Herpesviral Protein Reveals an Extended Recognition Motif that Enhances Binding Affinity. Protein Sci., 14, 2005
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1VPU
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![BU of 1vpu by Molmil](/molmil-images/mine/1vpu) | |
1WA7
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![BU of 1wa7 by Molmil](/molmil-images/mine/1wa7) | SH3 DOMAIN OF HUMAN LYN TYROSINE KINASE IN COMPLEX WITH A HERPESVIRAL LIGAND | Descriptor: | HYPOTHETICAL 28.7 KDA PROTEIN IN DHFR 3'REGION (ORF1), TYROSINE-PROTEIN KINASE LYN | Authors: | Bauer, F, Schweimer, K, Hoffmann, S, Roesch, P, Sticht, H. | Deposit date: | 2004-10-25 | Release date: | 2005-07-07 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | Structural Investigation of the Binding of a Herpesviral Protein to the SH3 Domain of Tyrosine Kinase Lck. Biochemistry, 41, 2002
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