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Yeast 20S proteasome beta5-G48C mutant in complex with alpha-chloroacetamide 1
Descriptor:	2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CHLORIDE ION, MAGNESIUM ION, ...
Authors:	Dubiella, C, Groll, M.
Deposit date:	2015-07-09
Release date:	2015-11-25
Last modified:	2024-01-10
Method:	X-RAY DIFFRACTION (2.9 Å)
Cite:	Selective Inhibition of the Immunoproteasome by Structure-Based Targeting of a Non-catalytic Cysteine. Angew.Chem.Int.Ed.Engl., 54, 2015

5CGH

Yeast 20S proteasome beta5-G48C mutant in complex with alpha-chloroacetamide 5
Descriptor:	2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CHLORIDE ION, MAGNESIUM ION, ...
Authors:	Dubiella, C, Groll, M.
Deposit date:	2015-07-09
Release date:	2015-12-02
Last modified:	2024-06-26
Method:	X-RAY DIFFRACTION (2.5 Å)
Cite:	Selective Inhibition of the Immunoproteasome by Structure-Based Targeting of a Non-catalytic Cysteine. Angew.Chem.Int.Ed.Engl., 54, 2015

5HBN

ClpC N-terminal domain with bound phospho-arginine
Descriptor:	ACETATE ION, Negative regulator of genetic competence ClpC/MecB, SULFATE ION, ...
Authors:	Suskiewicz, M.J, Clausen, T.
Deposit date:	2016-01-01
Release date:	2016-10-12
Last modified:	2024-01-10
Method:	X-RAY DIFFRACTION (1.602 Å)
Cite:	Arginine phosphorylation marks proteins for degradation by a Clp protease. Nature, 539, 2016

7AA4

Structure of ClpC1-NTD bound to a CymA analogue
Descriptor:	Negative regulator of genetic competence ClpC/mecB, polymer Cyclomarin A analogue
Authors:	Meinhart, A, Morreale, F.E, Kaiser, M, Clausen, T.
Deposit date:	2020-09-03
Release date:	2021-08-11
Last modified:	2024-01-31
Method:	X-RAY DIFFRACTION (1.68 Å)
Cite:	BacPROTACs mediate targeted protein degradation in bacteria. Cell, 185, 2022

7ABR

Cryo-EM structure of B. subtilis ClpC (DWB mutant) hexamer bound to a substrate polypeptide
Descriptor:	ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, Negative regulator of genetic competence ClpC/MecB, ...
Authors:	Morreale, F.E, Meinhart, A, Haselbach, D, Clausen, T.
Deposit date:	2020-09-08
Release date:	2021-10-06
Last modified:	2022-07-06
Method:	ELECTRON MICROSCOPY (3.7 Å)
Cite:	BacPROTACs mediate targeted protein degradation in bacteria. Cell, 185, 2022

5M2B

Yeast 20S proteasome with human beta5i (1-138) and human beta6 (97-111; 118-133) in complex with thiazole based inhibitor Ro19
Descriptor:	(2~{S})-2-cyclohexyl-4-oxidanylidene-4-[[7-(4-phenyl-1,3-thiazol-2-yl)quinolin-2-yl]amino]butanoic acid, CHLORIDE ION, MAGNESIUM ION, ...
Authors:	Groll, M.
Deposit date:	2016-10-12
Release date:	2017-01-25
Last modified:	2024-01-17
Method:	X-RAY DIFFRACTION (2.7 Å)
Cite:	Structural Elucidation of a Nonpeptidic Inhibitor Specific for the Human Immunoproteasome. Chembiochem, 18, 2017

4RQZ

re-refinement of 1soz, Crystal Structure of DegS protease in complex with an activating peptide
Descriptor:	Protease degS, activating peptide
Authors:	Sauer, R.T, Grant, R.A.
Deposit date:	2014-11-05
Release date:	2015-03-11
Last modified:	2024-02-28
Method:	X-RAY DIFFRACTION (2.4 Å)
Cite:	A Conserved Activation Cluster Is Required for Allosteric Communication in HtrA-Family Proteases. Structure, 23, 2015

4RR1

re-refinement of entry 1sot, Crystal Structure of the DegS stress sensor
Descriptor:	NICKEL (II) ION, PHOSPHATE ION, Protease degS
Authors:	Sauer, R.T, Grant, R.A.
Deposit date:	2014-11-05
Release date:	2015-03-11
Last modified:	2015-03-18
Method:	X-RAY DIFFRACTION (2.3 Å)
Cite:	A Conserved Activation Cluster Is Required for Allosteric Communication in HtrA-Family Proteases. Structure, 23, 2015

4RR0

re-refined 1vcw, CRYSTAL STRUCTURE OF DEGS AFTER BACKSOAKING THE ACTIVATING PEPTIDE
Descriptor:	Protease degS
Authors:	Sauer, R.T, Grant, R.A.
Deposit date:	2014-11-05
Release date:	2015-03-11
Last modified:	2024-02-28
Method:	X-RAY DIFFRACTION (3.054 Å)
Cite:	A Conserved Activation Cluster Is Required for Allosteric Communication in HtrA-Family Proteases. Structure, 23, 2015

3EX9

Crystal structure of PhzA/B from Burkholderia cepacia R18194 crystallized in C2221
Descriptor:	Phenazine biosynthesis protein A/B
Authors:	Ahuja, E.G, Blankenfeldt, W.
Deposit date:	2008-10-16
Release date:	2008-12-30
Last modified:	2023-11-01
Method:	X-RAY DIFFRACTION (2.2 Å)
Cite:	PhzA/B Catalyzes the Formation of the Tricycle in Phenazine Biosynthesis. J.Am.Chem.Soc., 130, 2008

2VTK

THYMIDINE KINASE FROM HERPES SIMPLEX VIRUS TYPE 1 IN COMPLEX WITH ADP AND DEOXYTHYMIDINE
Descriptor:	ADENOSINE-5'-DIPHOSPHATE, THYMIDINE, THYMIDINE KINASE
Authors:	Wild, K, Schulz, G.E.
Deposit date:	1997-04-01
Release date:	1997-10-22
Last modified:	2024-02-21
Method:	X-RAY DIFFRACTION (2.8 Å)
Cite:	The structures of thymidine kinase from herpes simplex virus type 1 in complex with substrates and a substrate analogue. Protein Sci., 6, 1997

3VTK

THYMIDINE KINASE FROM HERPES SIMPLEX VIRUS TYPE 1 IN COMPLEX WITH ADP AND 5-IODO-DEOXYURIDINE-MONOPHOSPHATE
Descriptor:	5-IODO-2'-DEOXYURIDINE-5'-MONOPHOSPHATE, ADENOSINE-5'-DIPHOSPHATE, THYMIDINE KINASE
Authors:	Wild, K, Schulz, G.E.
Deposit date:	1997-04-01
Release date:	1997-10-22
Last modified:	2024-02-28
Method:	X-RAY DIFFRACTION (3 Å)
Cite:	The structures of thymidine kinase from herpes simplex virus type 1 in complex with substrates and a substrate analogue. Protein Sci., 6, 1997

3TCT

Structure of wild-type TTR in complex with tafamidis
Descriptor:	2-(3,5-dichlorophenyl)-1,3-benzoxazole-6-carboxylic acid, Transthyretin
Authors:	Connelly, S, Kelly, J.W, Wilson, I.A.
Deposit date:	2011-08-09
Release date:	2012-05-30
Last modified:	2023-09-13
Method:	X-RAY DIFFRACTION (1.3 Å)
Cite:	Tafamidis, a potent and selective transthyretin kinetic stabilizer that inhibits the amyloid cascade. Proc.Natl.Acad.Sci.USA, 109, 2012

1DTK

THE NMR SOLUTION STRUCTURE OF DENDROTOXIN K FROM THE VENOM OF DENDROASPIS POLYLEPIS POLYLEPIS
Descriptor:	DENDROTOXIN K
Authors:	Berndt, K, Guntert, P, Wuthrich, K.
Deposit date:	1993-04-02
Release date:	1994-01-31
Last modified:	2022-02-16
Method:	SOLUTION NMR
Cite:	Nuclear magnetic resonance solution structure of dendrotoxin K from the venom of Dendroaspis polylepis polylepis. J.Mol.Biol., 234, 1993

1VTK

THYMIDINE KINASE FROM HERPES SIMPLEX VIRUS TYPE 1 IN COMPLEX WITH ADP AND DEOXYTHYMIDINE-MONOPHOSPHATE
Descriptor:	ADENOSINE-5'-DIPHOSPHATE, THYMIDINE KINASE, THYMIDINE-5'-PHOSPHATE
Authors:	Wild, K, Schulz, G.E.
Deposit date:	1997-04-01
Release date:	1997-10-22
Last modified:	2024-02-14
Method:	X-RAY DIFFRACTION (2.75 Å)
Cite:	The structures of thymidine kinase from herpes simplex virus type 1 in complex with substrates and a substrate analogue. Protein Sci., 6, 1997

1EE3

Cadmium-substituted bovine pancreatic carboxypeptidase A (alfa-form) at pH 7.5 and 2 mM chloride in monoclinic crystal form
Descriptor:	CADMIUM ION, PROTEIN (CARBOXYPEPTIDASE A)
Authors:	Jensen, F, Bukrinsky, T, Bjerrum, J, Larsen, S.
Deposit date:	2000-01-30
Release date:	2002-06-26
Last modified:	2023-09-20
Method:	X-RAY DIFFRACTION (1.7 Å)
Cite:	Three high-resolution crystal structures of cadmium-substituted carboxypeptidase A provide insight into the enzymatic function J.BIOL.INORG.CHEM., 7, 2002

1ELL

CADMIUM-SUBSTITUTED BOVINE PANCREATIC CARBOXYPEPTIDASE A (ALFA-FORM) AT PH 7.5 AND 0.25 M CHLORIDE IN MONOCLINIC CRYSTAL FORM.
Descriptor:	CADMIUM ION, CARBOXYPEPTIDASE A
Authors:	Jensen, F, Bukrinsky, T, Bjerrum, J, Larsen, S.
Deposit date:	2000-03-14
Release date:	2002-06-26
Last modified:	2023-09-20
Method:	X-RAY DIFFRACTION (1.76 Å)
Cite:	Three high-resolution crystal structures of cadmium-substituted carboxypeptidase A provide insight into the enzymatic function J.BIOL.INORG.CHEM., 7, 2002

1ELM

CADMIUM-SUBSTITUTED BOVINE PACREATIC CARBOXYPEPTIDASE A (ALFA-FORM) AT PH 5.5 AND 2 MM CHLORIDE IN MONOCLINIC CRYSTAL FORM.
Descriptor:	CADMIUM ION, CARBOXYPEPTIDASE A
Authors:	Jensen, F, Bukrinsky, T, Bjerrum, J, Larsen, S.
Deposit date:	2000-03-14
Release date:	2002-06-26
Last modified:	2023-09-20
Method:	X-RAY DIFFRACTION (2 Å)
Cite:	Three high-resolution crystal structures of cadmium-substituted carboxypeptidase A provide insight into the enzymatic function J.BIOL.INORG.CHEM., 7, 2002

2IUN

Structure of the C-terminal head domain of the avian adenovirus CELO long fibre (P21 crystal form)
Descriptor:	AVIAN ADENOVIRUS CELO LONG FIBRE, CALCIUM ION
Authors:	Guardado-Calvo, P, Llamas-Saiz, A.L, Fox, G.C, van Raaij, M.J.
Deposit date:	2006-06-06
Release date:	2007-06-19
Last modified:	2023-12-13
Method:	X-RAY DIFFRACTION (2.8 Å)
Cite:	Structure of the C-terminal head domain of the fowl adenovirus type 1 long fiber. J. Gen. Virol., 88, 2007

2IUM

Structure of the C-terminal head domain of the avian adenovirus CELO long fibre (C2 crystal form)
Descriptor:	AVIAN ADENOVIRUS CELO LONG FIBRE
Authors:	Guardado-Calvo, P, Llamas-Saiz, A.L, Fox, G.C, van Raaij, M.J.
Deposit date:	2006-06-06
Release date:	2007-06-19
Last modified:	2024-05-08
Method:	X-RAY DIFFRACTION (1.6 Å)
Cite:	Structure of the C-terminal head domain of the fowl adenovirus type 1 long fiber. J. Gen. Virol., 88, 2007

2INY

Nanoporous Crystals of Chicken Embryo Lethal Orphan (CELO) Adenovirus Major Coat Protein, Hexon
Descriptor:	Hexon protein
Authors:	Xu, L, Benson, S.D, Burnett, R.M.
Deposit date:	2006-10-09
Release date:	2007-02-06
Last modified:	2023-08-30
Method:	X-RAY DIFFRACTION (3.9 Å)
Cite:	Nanoporous crystals of chicken embryo lethal orphan (CELO) adenovirus major coat protein, hexon. J.Struct.Biol., 157, 2007

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Displayed results:	21
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