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5CGG

Yeast 20S proteasome beta5-G48C mutant in complex with alpha-chloroacetamide 1

Summary for 5CGG
Entry DOI10.2210/pdb5cgg/pdb
Related1RYP
DescriptorProteasome subunit alpha type-2, Proteasome subunit beta type-4, Proteasome subunit beta type-5, ... (19 entities in total)
Functional Keywordshydrolase-hydrolase inhibitor complex, proteasome, mutant, inhibitor, binding analysis, hydrolase/hydrolase inhibitor
Biological sourceSaccharomyces cerevisiae (strain ATCC 204508 / S288c)
More
Total number of polymer chains30
Total formula weight733143.24
Authors
Dubiella, C.,Groll, M. (deposition date: 2015-07-09, release date: 2015-11-25, Last modification date: 2024-01-10)
Primary citationDubiella, C.,Baur, R.,Cui, H.,Huber, E.M.,Groll, M.
Selective Inhibition of the Immunoproteasome by Structure-Based Targeting of a Non-catalytic Cysteine.
Angew.Chem.Int.Ed.Engl., 54:15888-15891, 2015
Cited by
PubMed: 26563572
DOI: 10.1002/anie.201506631
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2.9 Å)
Structure validation

217705

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