4UC9
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![BU of 4uc9 by Molmil](/molmil-images/mine/4uc9) | N-terminal globular domain of the RSV Nucleoprotein in complex with C- terminal dipeptide of the Phosphoprotein | Descriptor: | ASPARTIC ACID, NUCLEOPROTEIN, PHENYLALANINE, ... | Authors: | Ouizougun-Oubari, M, Pereira, N, Tarus, B, Galloux, M, Tortorici, M.-A, Hoos, S, Baron, B, England, P, Bontems, F, Rey, F.A, Eleouet, J.-F, Sizun, C, Slama-Schwok, A, Duquerroy, S. | Deposit date: | 2014-12-03 | Release date: | 2015-08-19 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | A Druggable Pocket at the Nucleocapsid/Phosphoprotein Interaction Site of the Human Respiratory Syncytial Virus. J.Virol., 89, 2015
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4UCA
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![BU of 4uca by Molmil](/molmil-images/mine/4uca) | N-terminal globular domain of the RSV Nucleoprotein in complex with C- terminal peptide of the Phosphoprotein | Descriptor: | NUCLEOPROTEIN, PHOSPHOSPROTEIN, SULFATE ION | Authors: | Ouizougun-Oubari, M, Pereira, N, Tarus, B, Galloux, M, Tortorici, M.-A, Hoos, S, Baron, B, England, P, Bontems, F, Rey, F.A, Eleouet, J.-F, Sizun, C, Slama-Schwok, A, Duquerroy, S. | Deposit date: | 2014-12-03 | Release date: | 2015-08-19 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (3.22 Å) | Cite: | A Druggable Pocket at the Nucleocapsid/Phosphoprotein Interaction Site of the Human Respiratory Syncytial Virus. J.Virol., 89, 2015
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3MKO
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![BU of 3mko by Molmil](/molmil-images/mine/3mko) | Crystal Structure of the Lymphocytic Choriomeningitis Virus Membrane Fusion Glycoprotein GP2 in its Postfusion Conformation | Descriptor: | (4S)-2-METHYL-2,4-PENTANEDIOL, CHLORIDE ION, Glycoprotein C, ... | Authors: | Igonet, S, Vaney, M.C, Rey, F.A. | Deposit date: | 2010-04-15 | Release date: | 2011-04-20 | Last modified: | 2017-11-08 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | X-ray structure of the arenavirus glycoprotein GP2 in its postfusion hairpin conformation Proc.Natl.Acad.Sci.USA, 108, 2011
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3NFL
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![BU of 3nfl by Molmil](/molmil-images/mine/3nfl) | Crystal structure of the PTPN4 PDZ domain complexed with the C-terminus of the GluN2A NMDA receptor subunit | Descriptor: | Glutamate [NMDA] receptor subunit epsilon-1, Tyrosine-protein phosphatase non-receptor type 4 | Authors: | Babault, N, Cordier, F, Lafage, M, Cockburn, J, Haouz, A, Rey, F.A, Delepierre, M, Buc, H, Lafon, M, Wolff, N. | Deposit date: | 2010-06-10 | Release date: | 2011-08-24 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (1.91 Å) | Cite: | Peptides Targeting the PDZ Domain of PTPN4 Are Efficient Inducers of Glioblastoma Cell Death. Structure, 19, 2011
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3NFK
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![BU of 3nfk by Molmil](/molmil-images/mine/3nfk) | Crystal structure of the PTPN4 PDZ domain complexed with the C-terminus of a rabies virus G protein | Descriptor: | GLYCEROL, Glycoprotein G, Tyrosine-protein phosphatase non-receptor type 4 | Authors: | Babault, N, Cordier, F, Lafage, M, Cockburn, J, Haouz, A, Rey, F.A, Delepierre, M, Buc, H, Lafon, M, Wolff, N. | Deposit date: | 2010-06-10 | Release date: | 2011-08-24 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (1.43 Å) | Cite: | Peptides Targeting the PDZ Domain of PTPN4 Are Efficient Inducers of Glioblastoma Cell Death. Structure, 19, 2011
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1WYY
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![BU of 1wyy by Molmil](/molmil-images/mine/1wyy) | Post-fusion hairpin conformation of the sars coronavirus spike glycoprotein | Descriptor: | CHLORIDE ION, E2 Glycoprotein | Authors: | Duquerroy, S, Vigouroux, A, Rottier, P.J.M, Rey, F.A, Bosch, B.J. | Deposit date: | 2005-02-18 | Release date: | 2005-05-17 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Central ions and lateral asparagine/glutamine zippers stabilize the post-fusion hairpin conformation of the SARS coronavirus spike glycoprotein Virology, 335, 2005
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1WCE
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![BU of 1wce by Molmil](/molmil-images/mine/1wce) | Crystal structure of the T13 IBDV viral particle reveals a missing link in icosahedral viruses evolution | Descriptor: | MAJOR STRUCTURAL PROTEIN VP2 | Authors: | Coulibaly, F, Chevalier, C, Gutsche, I, Pous, J, Bressanelli, S, Navaza, J, Delmas, B, Rey, F.A. | Deposit date: | 2004-11-12 | Release date: | 2005-04-06 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (7 Å) | Cite: | The Birnavirus Crystal Structure Reveals Structural Relationships Among Icosahedral Viruses. Cell(Cambridge,Mass.), 120, 2005
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2XHU
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![BU of 2xhu by Molmil](/molmil-images/mine/2xhu) | HCV-J4 NS5B Polymerase Orthorhombic Crystal Form | Descriptor: | RNA-directed RNA polymerase, SULFATE ION | Authors: | Harrus, D, Ahmed-El-Sayed, N, Simister, P.C, Miller, S, Triconnet, M, Hagedorn, C.H, Mahias, K, Rey, F.A, Astier-Gin, T, Bressanelli, S. | Deposit date: | 2010-06-21 | Release date: | 2010-08-04 | Last modified: | 2024-03-27 | Method: | X-RAY DIFFRACTION (2.287 Å) | Cite: | Further Insights Into the Roles of GTP and the C- Terminus of the Hepatitis C Virus Polymerase in the Initiation of RNA Synthesis J.Biol.Chem., 285, 2010
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2XFC
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![BU of 2xfc by Molmil](/molmil-images/mine/2xfc) | CHIKUNGUNYA E1 E2 ENVELOPE GLYCOPROTEINS FITTED IN SEMLIKI FOREST VIRUS cryo-EM MAP | Descriptor: | E1 ENVELOPE GLYCOPROTEIN, E2 ENVELOPE GLYCOPROTEIN | Authors: | Voss, J.E, Vaney, M.C, Duquerroy, S, Rey, F.A. | Deposit date: | 2010-05-21 | Release date: | 2010-11-24 | Last modified: | 2019-10-23 | Method: | ELECTRON MICROSCOPY (9 Å) | Cite: | Glycoprotein Organization of Chikungunya Virus Particles Revealed by X-Ray Crystallography Nature, 468, 2010
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2XXM
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![BU of 2xxm by Molmil](/molmil-images/mine/2xxm) | Crystal structure of the HIV-1 capsid protein C-terminal domain in complex with a camelid VHH and the CAI peptide. | Descriptor: | ACETATE ION, CAMELID VHH 9, CAPSID PROTEIN P24, ... | Authors: | Igonet, S, Vaney, M.C, Bartonova, V, Helma, J, Rothbauer, U, Leonhardt, H, Stura, E, Krausslich, H.-G, Rey, F.A. | Deposit date: | 2010-11-10 | Release date: | 2011-10-12 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (1.65 Å) | Cite: | Targeting HIV-1 Virion Formation with Nanobodies -Implications for the Design of Assembly Inhibitors To be Published
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2XHV
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![BU of 2xhv by Molmil](/molmil-images/mine/2xhv) | HCV-J4 NS5B Polymerase Point Mutant Orthorhombic Crystal Form | Descriptor: | MAGNESIUM ION, RNA-directed RNA polymerase, SULFATE ION | Authors: | Harrus, D, Ahmed-El-Sayed, N, Simister, P.C, Miller, S, Triconnet, M, Hagedorn, C.H, Mahias, K, Rey, F.A, Astier-Gin, T, Bressanelli, S. | Deposit date: | 2010-06-21 | Release date: | 2010-08-04 | Last modified: | 2024-03-27 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Further Insights Into the Roles of GTP and the C- Terminus of the Hepatitis C Virus Polymerase in the Initiation of RNA Synthesis J.Biol.Chem., 285, 2010
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2XI3
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![BU of 2xi3 by Molmil](/molmil-images/mine/2xi3) | HCV-H77 NS5B Polymerase Complexed With GTP | Descriptor: | GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, RNA-directed RNA polymerase | Authors: | Harrus, D, Ahmed-El-Sayed, N, Simister, P.C, Miller, S, Triconnet, M, Hagedorn, C.H, Mahias, K, Rey, F.A, Astier-Gin, T, Bressanelli, S. | Deposit date: | 2010-06-25 | Release date: | 2010-08-04 | Last modified: | 2024-03-27 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Further Insights Into the Roles of GTP and the C- Terminus of the Hepatitis C Virus Polymerase in the Initiation of RNA Synthesis J.Biol.Chem., 285, 2010
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2XHW
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![BU of 2xhw by Molmil](/molmil-images/mine/2xhw) | HCV-J4 NS5B Polymerase Trigonal Crystal Form | Descriptor: | RNA-directed RNA polymerase | Authors: | Harrus, D, Ahmed-El-Sayed, N, Simister, P.C, Miller, S, Triconnet, M, Hagedorn, C.H, Mahias, K, Rey, F.A, Astier-Gin, T, Bressanelli, S. | Deposit date: | 2010-06-21 | Release date: | 2010-08-04 | Last modified: | 2024-03-27 | Method: | X-RAY DIFFRACTION (2.66 Å) | Cite: | Further Insights Into the Roles of GTP and the C- Terminus of the Hepatitis C Virus Polymerase in the Initiation of RNA Synthesis J.Biol.Chem., 285, 2010
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2XXC
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![BU of 2xxc by Molmil](/molmil-images/mine/2xxc) | Crystal structure of a camelid VHH raised against the HIV-1 capsid protein C-terminal domain. | Descriptor: | CAMELID VHH 9 | Authors: | Igonet, S, Vaney, M.C, Bartonova, V, Helma, J, Rothbauer, U, Leonhardt, H, Stura, E, Krausslich, H.-G, Rey, F.A. | Deposit date: | 2010-11-10 | Release date: | 2011-10-12 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (1.67 Å) | Cite: | Targeting HIV-1 Virion Formation with Nanobodies -Implications for the Design of Assembly Inhibitors To be Published
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2XT1
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![BU of 2xt1 by Molmil](/molmil-images/mine/2xt1) | Crystal structure of the HIV-1 capsid protein C-terminal domain (146- 231) in complex with a camelid VHH. | Descriptor: | CAMELID VHH 9, GAG POLYPROTEIN, GLYCEROL | Authors: | Igonet, S, Vaney, M.C, Bartonova, V, Helma, J, Rothbauer, U, Leonhardt, H, Stura, E, Krausslich, H.-G, Rey, F.A. | Deposit date: | 2010-10-03 | Release date: | 2011-10-12 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (1.32 Å) | Cite: | Targeting HIV-1 Virion Formation with Nanobodies -Implications for the Design of Assembly Inhibitors To be Published
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2XV6
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![BU of 2xv6 by Molmil](/molmil-images/mine/2xv6) | Crystal structure of the HIV-1 capsid protein C-terminal domain (146- 220) in complex with a camelid VHH. | Descriptor: | CAMELID VHH 9, CAPSID PROTEIN P24 | Authors: | Igonet, S, Vaney, M.C, Bartonova, V, Helma, J, Rothbauer, U, Leonhardt, H, Stura, E, Krausslich, H.-G, Rey, F.A. | Deposit date: | 2010-10-22 | Release date: | 2011-10-12 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (1.89 Å) | Cite: | Targeting HIV-1 Virion Formation with Nanobodies -Implications for the Design of Assembly Inhibitors To be Published
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1Y4M
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![BU of 1y4m by Molmil](/molmil-images/mine/1y4m) | Crystal structure of human endogenous retrovirus HERV-FRD envelope protein (syncitin-2) | Descriptor: | CHLORIDE ION, HERV-FRD_6p24.1 provirus ancestral Env polyprotein | Authors: | Renard, M, Varela, P.F, Letzelter, C, Duquerroy, S, Rey, F.A, Heidmann, T. | Deposit date: | 2004-12-01 | Release date: | 2005-11-15 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Crystal structure of a pivotal domain of human syncytin-2, a 40 million years old endogenous retrovirus fusogenic envelope gene captured by primates. J.Mol.Biol., 352, 2005
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1CSJ
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![BU of 1csj by Molmil](/molmil-images/mine/1csj) | CRYSTAL STRUCTURE OF THE RNA-DEPENDENT RNA POLYMERASE OF HEPATITIS C VIRUS | Descriptor: | HEPATITIS C VIRUS RNA POLYMERASE (NS5B) | Authors: | Bressanelli, S, Tomei, L, Roussel, A, Incitti, I, Vitale, R.L, Mathieu, M, De Francesco, R, Rey, F.A. | Deposit date: | 1999-08-18 | Release date: | 1999-11-08 | Last modified: | 2013-02-13 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Crystal structure of the RNA-dependent RNA polymerase of hepatitis C virus. Proc.Natl.Acad.Sci.USA, 96, 1999
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7QF1
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![BU of 7qf1 by Molmil](/molmil-images/mine/7qf1) | Crystal structure of the SARS-CoV-2 RBD in complex with the human antibody CV2.6264 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CV2.6264 heavy chain, CV2.6264 light chain, ... | Authors: | Fernandez, I, Pederzoli, R, Rey, F.A. | Deposit date: | 2021-12-03 | Release date: | 2022-05-18 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Potent human broadly SARS-CoV-2-neutralizing IgA and IgG antibodies effective against Omicron BA.1 and BA.2. J.Exp.Med., 219, 2022
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7QF0
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![BU of 7qf0 by Molmil](/molmil-images/mine/7qf0) | Crystal structure of the SARS-CoV-2 RBD in complex with the human antibody CV2.2325 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, CV2.2325 heavy chain, ... | Authors: | Fernandez, I, Pederzoli, R, Rey, F.A. | Deposit date: | 2021-12-03 | Release date: | 2022-05-18 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Potent human broadly SARS-CoV-2-neutralizing IgA and IgG antibodies effective against Omicron BA.1 and BA.2. J.Exp.Med., 219, 2022
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7QEZ
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![BU of 7qez by Molmil](/molmil-images/mine/7qez) | |
5MZ4
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![BU of 5mz4 by Molmil](/molmil-images/mine/5mz4) | Crystal Structure of full-lengh CSFV NS3/4A | Descriptor: | Genome polyprotein,Genome polyprotein | Authors: | Tortorici, M.A, Rey, F.A. | Deposit date: | 2017-01-30 | Release date: | 2017-02-15 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (3.048 Å) | Cite: | A positive-strand RNA virus uses alternative protein-protein interactions within a viral protease/cofactor complex to switch between RNA replication and virion morphogenesis. PLoS Pathog., 13, 2017
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5NPI
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![BU of 5npi by Molmil](/molmil-images/mine/5npi) | |
5NPH
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![BU of 5nph by Molmil](/molmil-images/mine/5nph) | |
5NPJ
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![BU of 5npj by Molmil](/molmil-images/mine/5npj) | |