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Cryo-EM structure of cystine-bound cystinosin in a lumen-open state
Descriptor:	Fab 3H5 Heavy Chain, Fab 3H5 Kappa chain, Isoform 2 of Cystinosin, ...
Authors:	Schmiege, P, Li, X.
Deposit date:	2022-07-05
Release date:	2022-09-21
Last modified:	2022-10-12
Method:	ELECTRON MICROSCOPY (3.39 Å)
Cite:	Structure and mechanism of human cystine exporter cystinosin. Cell, 185, 2022

8DKX

Cryo-EM structure of cystinosin N288K mutant in a cytosol-open state at pH7.5
Descriptor:	Fab 3H5 Heavy Chain, Fab 3H5 Kappa Chain, Isoform 2 of Cystinosin
Authors:	Schmiege, P, Li, X.
Deposit date:	2022-07-06
Release date:	2022-09-21
Last modified:	2022-10-12
Method:	ELECTRON MICROSCOPY (3 Å)
Cite:	Structure and mechanism of human cystine exporter cystinosin. Cell, 185, 2022

8DKW

Cryo-EM structure of cystinosin N288K mutant in a cytosol-open state at pH5.0
Descriptor:	Fab 3H5 Heavy Chain, Fab 3H5 Kappa Chain, Isoform 2 of Cystinosin
Authors:	Schmiege, P, Li, X.
Deposit date:	2022-07-06
Release date:	2022-09-21
Last modified:	2022-10-12
Method:	ELECTRON MICROSCOPY (3.09 Å)
Cite:	Structure and mechanism of human cystine exporter cystinosin. Cell, 185, 2022

8DKE

Cryo-EM structure of cystinosin in a cytosol-open state
Descriptor:	Fab 3H5 Heavy chain, Fab 3H5 Kappa chain, Isoform 2 of Cystinosin
Authors:	Schmiege, P, Li, X.
Deposit date:	2022-07-05
Release date:	2022-09-21
Last modified:	2022-10-12
Method:	ELECTRON MICROSCOPY (3.18 Å)
Cite:	Structure and mechanism of human cystine exporter cystinosin. Cell, 185, 2022

5H24

EED in complex with PRC2 allosteric inhibitor compound 8
Descriptor:	5-(furan-2-ylmethylamino)-[1,2,4]triazolo[4,3-a]pyridine-6-carbonitrile, Histone-lysine N-methyltransferase EZH2, Polycomb protein EED
Authors:	Zhao, K, Zhao, M, Luo, X, Zhang, H.
Deposit date:	2016-10-14
Release date:	2017-01-25
Last modified:	2023-11-08
Method:	X-RAY DIFFRACTION (2.5 Å)
Cite:	Discovery of First-in-Class, Potent, and Orally Bioavailable Embryonic Ectoderm Development (EED) Inhibitor with Robust Anticancer Efficacy J. Med. Chem., 60, 2017

5D06

Crystal Structure of the Candida Glabrata Glycogen Debranching Enzyme
Descriptor:	Uncharacterized protein
Authors:	Zhai, L, Xiang, S.
Deposit date:	2015-08-02
Release date:	2016-05-18
Last modified:	2016-12-14
Method:	X-RAY DIFFRACTION (3.1 Å)
Cite:	Crystal structure of glycogen debranching enzyme and insights into its catalysis and disease-causing mutations. Nat Commun, 7, 2016

5D0F

Crystal Structure of the Candida Glabrata Glycogen Debranching Enzyme (E564Q) in complex with maltopentaose
Descriptor:	Uncharacterized protein, alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose, alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose, ...
Authors:	Zhai, L, Xiang, S.
Deposit date:	2015-08-03
Release date:	2016-05-18
Last modified:	2023-11-08
Method:	X-RAY DIFFRACTION (3.3 Å)
Cite:	Crystal structure of glycogen debranching enzyme and insights into its catalysis and disease-causing mutations. Nat Commun, 7, 2016

5INW

Structure of reaction loop cleaved lamprey angiotensinogen
Descriptor:	C-terminal peptide of Putative angiotensinogen, Putative angiotensinogen, SULFATE ION
Authors:	Wei, H, Zhou, A.
Deposit date:	2016-03-08
Release date:	2016-10-05
Last modified:	2023-11-08
Method:	X-RAY DIFFRACTION (2.7 Å)
Cite:	Heparin Binds Lamprey Angiotensinogen and Promotes Thrombin Inhibition through a Template Mechanism J.Biol.Chem., 291, 2016

6RNW

The crystal structure of Thermosynechococcus elongatus protochlorophyllide oxidoreductase (POR) in complex with NADP.
Descriptor:	NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, NADPH-protochlorophyllide oxidoreductase
Authors:	Levy, C.W.
Deposit date:	2019-05-09
Release date:	2019-10-30
Last modified:	2024-01-24
Method:	X-RAY DIFFRACTION (1.92 Å)
Cite:	Structural basis for enzymatic photocatalysis in chlorophyll biosynthesis. Nature, 574, 2019

6RNV

The crystal structure of Thermosynechococcus elongatus protochlorophyllide oxidoreductase (POR)
Descriptor:	CHLORIDE ION, Thermosynechococcus elongatus protochlorophyllide oxidoreductase (POR)
Authors:	Levy, C.W.
Deposit date:	2019-05-09
Release date:	2019-10-30
Last modified:	2024-01-24
Method:	X-RAY DIFFRACTION (1.27 Å)
Cite:	Structural basis for enzymatic photocatalysis in chlorophyll biosynthesis. Nature, 574, 2019

2ZGO

Crystal structure of AAL mutant H59Q complex with lactose
Descriptor:	Anti-tumor lectin, beta-D-galactopyranose-(1-4)-beta-D-glucopyranose
Authors:	Li, D.F, Yang, N, Wang, D.C.
Deposit date:	2008-01-23
Release date:	2009-01-20
Last modified:	2023-11-01
Method:	X-RAY DIFFRACTION (2 Å)
Cite:	Structural basis for the tumor cell apoptosis-inducing activity of an antitumor lectin from the edible mushroom Agrocybe aegerita J.Mol.Biol., 387, 2009

2ZGP

Crystal structure of Agrocybe aegerita lectin AAL mutant I25G
Descriptor:	Anti-tumor lectin
Authors:	Yang, N, Li, D.F, Wang, D.C.
Deposit date:	2008-01-23
Release date:	2009-01-20
Last modified:	2023-11-01
Method:	X-RAY DIFFRACTION (2.7 Å)
Cite:	Structural basis for the tumor cell apoptosis-inducing activity of an antitumor lectin from the edible mushroom Agrocybe aegerita J.Mol.Biol., 387, 2009

2ZGL

Crystal structure of recombinant Agrocybe aegerita (rAAL)
Descriptor:	Anti-tumor lectin
Authors:	Yang, N, Li, D.F, Wang, D.C.
Deposit date:	2008-01-23
Release date:	2009-01-20
Last modified:	2023-11-01
Method:	X-RAY DIFFRACTION (1.9 Å)
Cite:	Structural basis for the tumor cell apoptosis-inducing activity of an antitumor lectin from the edible mushroom Agrocybe aegerita J.Mol.Biol., 387, 2009

2ZGN

crystal structure of recombinant Agrocybe aegerita lectin, rAAL, complex with galactose
Descriptor:	Anti-tumor lectin, beta-D-galactopyranose
Authors:	Yang, N, Li, D.F, Wang, D.C.
Deposit date:	2008-01-23
Release date:	2009-01-20
Last modified:	2023-11-01
Method:	X-RAY DIFFRACTION (2.5 Å)
Cite:	Structural basis for the tumor cell apoptosis-inducing activity of an antitumor lectin from the edible mushroom Agrocybe aegerita J.Mol.Biol., 387, 2009

2ZGS

Crystal structure of Agrocybe aegerita lectin AAL mutant L47A
Descriptor:	Anti-tumor lectin
Authors:	Li, D.F, Yang, N, Wang, D.C.
Deposit date:	2008-01-23
Release date:	2009-01-20
Last modified:	2023-11-01
Method:	X-RAY DIFFRACTION (1.9 Å)
Cite:	Structural basis for the tumor cell apoptosis-inducing activity of an antitumor lectin from the edible mushroom Agrocybe aegerita J.Mol.Biol., 387, 2009

2ZGR

Crystal structure of AAL mutant L33A in C2 spacegroup
Descriptor:	Anti-tumor lectin
Authors:	Yang, N, Li, D.F, Wang, D.C.
Deposit date:	2008-01-23
Release date:	2009-01-20
Last modified:	2023-11-01
Method:	X-RAY DIFFRACTION (1.9 Å)
Cite:	Structural basis for the tumor cell apoptosis-inducing activity of an antitumor lectin from the edible mushroom Agrocybe aegerita J.Mol.Biol., 387, 2009

1C78

STAPHYLOKINASE (SAK) DIMER
Descriptor:	STAPHYLOKINASE
Authors:	Rao, Z, Jiang, F, Liu, Y, Zhang, X, Chen, Y, Bartlam, M, Song, H, Ding, Y.
Deposit date:	2000-02-01
Release date:	2000-08-01
Last modified:	2023-12-27
Method:	X-RAY DIFFRACTION (2.3 Å)
Cite:	Crystal structure of a staphylokinase: variant a model for reduced antigenicity. Eur.J.Biochem., 269, 2002

1C77

STAPHYLOKINASE (SAK) DIMER
Descriptor:	STAPHYLOKINASE
Authors:	Rao, Z, Jiang, F, Liu, Y, Zhang, X, Chen, Y, Bartlam, M, Song, H, Ding, Y.
Deposit date:	2000-02-01
Release date:	2000-08-01
Last modified:	2023-12-27
Method:	X-RAY DIFFRACTION (2.3 Å)
Cite:	Crystal structure of a staphylokinase: variant a model for reduced antigenicity. Eur.J.Biochem., 269, 2002

1C79

STAPHYLOKINASE (SAK) DIMER
Descriptor:	STAPHYLOKINASE
Authors:	Rao, Z, Jiang, F, Liu, Y, Zhang, X, Chen, Y, Bartlam, M, Song, H, Ding, Y.
Deposit date:	2000-02-01
Release date:	2000-08-01
Last modified:	2023-12-27
Method:	X-RAY DIFFRACTION (2.3 Å)
Cite:	Crystal structure of a staphylokinase: variant a model for reduced antigenicity. Eur.J.Biochem., 269, 2002

3CX4

Crystal Structure of E.coli GS mutant E377A in complex with ADP and oligosaccharides
Descriptor:	(2R)-2-hydroxy-3-[4-(2-hydroxyethyl)piperazin-1-yl]propane-1-sulfonic acid, 2-{2-[2-2-(METHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHANOL, ADENOSINE-5'-DIPHOSPHATE, ...
Authors:	Sheng, F, Geiger, J.H.
Deposit date:	2008-04-23
Release date:	2009-04-28
Last modified:	2023-08-30
Method:	X-RAY DIFFRACTION (2.29 Å)
Cite:	Oligosaccharide binding in Escherichia coli glycogen synthase. Biochemistry, 48, 2009

2ZGU

Crystal structure Agrocybe aegerita lectin AAL mutant I144G
Descriptor:	Anti-tumor lectin
Authors:	Li, D.F, Yang, N, Wang, D.C.
Deposit date:	2008-01-23
Release date:	2009-01-20
Last modified:	2023-11-01
Method:	X-RAY DIFFRACTION (2.4 Å)
Cite:	Structural basis for the tumor cell apoptosis-inducing activity of an antitumor lectin from the edible mushroom Agrocybe aegerita J.Mol.Biol., 387, 2009

2ZGT

Crystal structure of Agrocybe aegerita lectin AAL mutant F93G
Descriptor:	Anti-tumor lectin
Authors:	Li, D.F, Yang, N, Wang, D.C.
Deposit date:	2008-01-23
Release date:	2009-01-20
Last modified:	2023-11-01
Method:	X-RAY DIFFRACTION (2.8 Å)
Cite:	Structural basis for the tumor cell apoptosis-inducing activity of an antitumor lectin from the edible mushroom Agrocybe aegerita J.Mol.Biol., 387, 2009

2ZGK

Crystal structure of wildtype AAL
Descriptor:	Anti-tumor lectin
Authors:	Yang, N, Li, D.F, Wang, D.C.
Deposit date:	2008-01-23
Release date:	2009-01-20
Last modified:	2024-03-13
Method:	X-RAY DIFFRACTION (3 Å)
Cite:	Structural basis for the tumor cell apoptosis-inducing activity of an antitumor lectin from the edible mushroom Agrocybe aegerita J.Mol.Biol., 387, 2009

2ZGM

Crystal structure of recombinant Agrocybe aegerita lectin,rAAL, complex with lactose
Descriptor:	Anti-tumor lectin, SULFATE ION, beta-D-galactopyranose-(1-4)-beta-D-glucopyranose
Authors:	Li, D.F, Yang, N, Wang, D.C.
Deposit date:	2008-01-23
Release date:	2009-01-20
Last modified:	2023-11-01
Method:	X-RAY DIFFRACTION (1.9 Å)
Cite:	Structural basis for the tumor cell apoptosis-inducing activity of an antitumor lectin from the edible mushroom Agrocybe aegerita J.Mol.Biol., 387, 2009

3FY0

Crystal structure of PAK1 kinase domain with ruthenium complex DW1
Descriptor:	Ruthenium pyridocarbazole, Serine/threonine-protein kinase PAK 1
Authors:	Maksimoska, J, Marmorstein, R, Meggers, E.
Deposit date:	2009-01-21
Release date:	2009-03-03
Last modified:	2021-10-20
Method:	X-RAY DIFFRACTION (2.35 Å)
Cite:	Targeting Large Kinase Active Site with Rigid, Bulky Octahedral Ruthenium Complexes J.Am.Chem.Soc., 130, 2008

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