6PTK
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![BU of 6ptk by Molmil](/molmil-images/mine/6ptk) | Crystal structure of the sulfatase PsS1_NC C84A with bound sulfate ion | Descriptor: | 1,2-ETHANEDIOL, 3,6-anhydro-D-galactose, 4-O-sulfo-beta-D-galactopyranose, ... | Authors: | Hettle, A.G, Boraston, A.B. | Deposit date: | 2019-07-16 | Release date: | 2019-09-25 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (1.75 Å) | Cite: | Insights into the kappa / iota-carrageenan metabolism pathway of some marinePseudoalteromonasspecies. Commun Biol, 2, 2019
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6PT6
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![BU of 6pt6 by Molmil](/molmil-images/mine/6pt6) | Crystal structure of PsS1_NC C84S in complex with i-neocarratetraose | Descriptor: | 3,6-anhydro-2-O-sulfo-alpha-D-galactopyranose-(1-3)-4-O-sulfo-beta-D-galactopyranose, CALCIUM ION, exo-2S-iota carrageenan S1 sulfatase | Authors: | Hettle, A.G, Boraston, A.B. | Deposit date: | 2019-07-15 | Release date: | 2019-09-25 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (2.25 Å) | Cite: | Insights into the kappa / iota-carrageenan metabolism pathway of some marinePseudoalteromonasspecies. Commun Biol, 2, 2019
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8KAE
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![BU of 8kae by Molmil](/molmil-images/mine/8kae) | 16d-bound human SPNS2 | Descriptor: | 3-[3-(4-decylphenyl)-1,2,4-oxadiazol-5-yl]propan-1-amine, NbFab chain L, NbFab-H chain, ... | Authors: | He, Y, Duan, Y. | Deposit date: | 2023-08-03 | Release date: | 2024-01-03 | Last modified: | 2024-02-21 | Method: | ELECTRON MICROSCOPY (3.18 Å) | Cite: | Structural basis of Sphingosine-1-phosphate transport via human SPNS2. Cell Res., 34, 2024
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2FEI
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![BU of 2fei by Molmil](/molmil-images/mine/2fei) | Solution structure of the second SH3 domain of Human CMS protein | Descriptor: | CD2-associated protein | Authors: | Yao, B, Dai, H, Jiao, Y, Wu, J, Shi, Y. | Deposit date: | 2005-12-15 | Release date: | 2006-12-05 | Last modified: | 2024-05-29 | Method: | SOLUTION NMR | Cite: | Solution structure of the second SH3 domain of human CMS and a newly identified binding site at the C-terminus of c-Cbl Biochim.Biophys.Acta, 1774, 2007
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7CM3
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![BU of 7cm3 by Molmil](/molmil-images/mine/7cm3) | Cryo-EM structure of human NALCN in complex with FAM155A | Descriptor: | 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | Authors: | Wu, J, Yan, Z, Ke, M. | Deposit date: | 2020-07-24 | Release date: | 2020-11-11 | Last modified: | 2020-12-02 | Method: | ELECTRON MICROSCOPY (3.1 Å) | Cite: | Structure of the human sodium leak channel NALCN in complex with FAM155A. Nat Commun, 11, 2020
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5XGH
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![BU of 5xgh by Molmil](/molmil-images/mine/5xgh) | Crystal structure of PI3K complex with an inhibitor | Descriptor: | 3-[(4-fluorophenyl)methylamino]-5-(4-morpholin-4-ylthieno[3,2-d]pyrimidin-2-yl)phenol, GLYCEROL, Phosphatidylinositol 3-kinase regulatory subunit alpha, ... | Authors: | Song, K, Yang, X, Zhao, Y, Jian, Z. | Deposit date: | 2017-04-13 | Release date: | 2018-04-25 | Last modified: | 2024-03-27 | Method: | X-RAY DIFFRACTION (2.97 Å) | Cite: | New Insights into PI3K Inhibitor Design using X-ray Structures of PI3K alpha Complexed with a Potent Lead Compound. Sci Rep, 7, 2017
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2Z3C
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![BU of 2z3c by Molmil](/molmil-images/mine/2z3c) | |
2Z3D
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![BU of 2z3d by Molmil](/molmil-images/mine/2z3d) | |
2Z3E
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![BU of 2z3e by Molmil](/molmil-images/mine/2z3e) | |
5Y18
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![BU of 5y18 by Molmil](/molmil-images/mine/5y18) | |
2Z8O
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![BU of 2z8o by Molmil](/molmil-images/mine/2z8o) | Structural basis for the catalytic mechanism of phosphothreonine lyase | Descriptor: | 27.5 kDa virulence protein, L(+)-TARTARIC ACID | Authors: | Chen, L, Wang, H, Gu, L, Huang, N, Zhou, J.M, Chai, J. | Deposit date: | 2007-09-07 | Release date: | 2007-12-18 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Structural basis for the catalytic mechanism of phosphothreonine lyase. Nat.Struct.Mol.Biol., 15, 2008
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6SJD
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![BU of 6sjd by Molmil](/molmil-images/mine/6sjd) | ZC3H12B-ribonuclease domain bound to RNA | Descriptor: | CACODYLATE ION, MAGNESIUM ION, Probable ribonuclease ZC3H12B, ... | Authors: | Morgunova, E, Bourenkov, G, Taipale, J. | Deposit date: | 2019-08-13 | Release date: | 2020-07-22 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (3.29 Å) | Cite: | Binding specificities of human RNA-binding proteins toward structured and linear RNA sequences. Genome Res., 30, 2020
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7WWL
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![BU of 7wwl by Molmil](/molmil-images/mine/7wwl) | S protein of Delta variant in complex with ZWD12 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein, ... | Authors: | Guo, Y.Y, Zhang, Y.Y, Zhou, Q. | Deposit date: | 2022-02-13 | Release date: | 2022-06-01 | Method: | ELECTRON MICROSCOPY (3 Å) | Cite: | Broadly neutralizing antibodies against Omicron-included SARS-CoV-2 variants induced by vaccination. Signal Transduct Target Ther, 7, 2022
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8TXG
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![BU of 8txg by Molmil](/molmil-images/mine/8txg) | Crystal structure of KRAS G12D in complex with GDP and compound 8 | Descriptor: | (4M)-4-(6-chloro-4-[(1R,5S)-3,8-diazabicyclo[3.2.1]octan-3-yl]-8-fluoro-2-{[(2R,4R,7aS)-2-fluorotetrahydro-1H-pyrrolizin-7a(5H)-yl]methoxy}quinazolin-7-yl)-7-fluoro-1,3-benzothiazol-2-amine, GTPase KRas, GUANOSINE-5'-DIPHOSPHATE, ... | Authors: | Chen, P, Irimia, A, Yang, Z. | Deposit date: | 2023-08-23 | Release date: | 2023-11-08 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | Structure-Based Design and Synthesis of Potent and Selective KRAS G12D Inhibitors. Acs Med.Chem.Lett., 14, 2023
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8TXH
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![BU of 8txh by Molmil](/molmil-images/mine/8txh) | Crystal structure of KRAS G12D in complex with GDP and compound 14 | Descriptor: | (4P)-2-amino-4-{4-[(1R,5S)-3,8-diazabicyclo[3.2.1]octan-3-yl]-8-fluoro-2-{[(2R,4R,7aS)-2-fluorotetrahydro-1H-pyrrolizin-7a(5H)-yl]methoxy}-6-(trifluoromethyl)quinazolin-7-yl}-7-fluoro-1-benzothiophene-3-carbonitrile, GTPase KRas, GUANOSINE-5'-DIPHOSPHATE, ... | Authors: | Chen, P, Irimia, A, Yang, Z. | Deposit date: | 2023-08-23 | Release date: | 2023-11-08 | Method: | X-RAY DIFFRACTION (1.2 Å) | Cite: | Structure-Based Design and Synthesis of Potent and Selective KRAS G12D Inhibitors. Acs Med.Chem.Lett., 14, 2023
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8TXE
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![BU of 8txe by Molmil](/molmil-images/mine/8txe) | Crystal structure of KRAS G12D in complex with GDP and compound 5 | Descriptor: | (6M)-6-(6-chloro-4-[(1R,5S)-3,8-diazabicyclo[3.2.1]octan-3-yl]-8-fluoro-2-{[(2R,4R,7aS)-2-fluorotetrahydro-1H-pyrrolizin-7a(5H)-yl]methoxy}quinazolin-7-yl)-4-methyl-5-(trifluoromethyl)pyridin-2-amine, GTPase KRas, GUANOSINE-5'-DIPHOSPHATE, ... | Authors: | Chen, P, Irimia, A, Yang, Z. | Deposit date: | 2023-08-23 | Release date: | 2023-11-08 | Method: | X-RAY DIFFRACTION (1.35 Å) | Cite: | Structure-Based Design and Synthesis of Potent and Selective KRAS G12D Inhibitors. Acs Med.Chem.Lett., 14, 2023
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6PRM
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![BU of 6prm by Molmil](/molmil-images/mine/6prm) | Crystal structure of apo PsS1_19B | Descriptor: | CALCIUM ION, exo-4S-kappa carrageenan S1 sulfatase | Authors: | Hettle, A.G, Boraston, A.B. | Deposit date: | 2019-07-10 | Release date: | 2019-09-25 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Insights into the kappa / iota-carrageenan metabolism pathway of some marinePseudoalteromonasspecies. Commun Biol, 2, 2019
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8YBR
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![BU of 8ybr by Molmil](/molmil-images/mine/8ybr) | Choline transporter BetT | Descriptor: | BCCT family transporter | Authors: | Yang, T.J, Nian, Y.W, Lin, H.J, Li, J, Zhang, J.R, Fan, M.R. | Deposit date: | 2024-02-16 | Release date: | 2024-09-04 | Method: | ELECTRON MICROSCOPY (2.57 Å) | Cite: | Structure and mechanism of the osmoregulated choline transporter BetT. Sci Adv, 10, 2024
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6PSM
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![BU of 6psm by Molmil](/molmil-images/mine/6psm) | Crystal structure of PsS1_19B C77S in complex with kappa-neocarrabiose | Descriptor: | 1,2-ETHANEDIOL, 3,6-anhydro-D-galactose, 4-O-sulfo-beta-D-galactopyranose, ... | Authors: | Hettle, A.G, Boraston, A.B. | Deposit date: | 2019-07-12 | Release date: | 2019-09-25 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (1.95 Å) | Cite: | Insights into the kappa / iota-carrageenan metabolism pathway of some marinePseudoalteromonasspecies. Commun Biol, 2, 2019
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6PT9
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![BU of 6pt9 by Molmil](/molmil-images/mine/6pt9) | Crystal structure of PsS1_NC C84S in complex with k-neocarrabiose | Descriptor: | 1,2-ETHANEDIOL, 3,6-anhydro-D-galactose, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, ... | Authors: | Hettle, A.G, Boraston, A.B. | Deposit date: | 2019-07-15 | Release date: | 2019-09-25 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (1.66 Å) | Cite: | Insights into the kappa / iota-carrageenan metabolism pathway of some marinePseudoalteromonasspecies. Commun Biol, 2, 2019
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6PT4
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![BU of 6pt4 by Molmil](/molmil-images/mine/6pt4) | Crystal structure of apo PsS1_NC | Descriptor: | 1,2-ETHANEDIOL, CALCIUM ION, CHLORIDE ION, ... | Authors: | Hettle, A.G, Boraston, A.B. | Deposit date: | 2019-07-14 | Release date: | 2019-09-25 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (1.45 Å) | Cite: | Insights into the kappa / iota-carrageenan metabolism pathway of some marinePseudoalteromonasspecies. Commun Biol, 2, 2019
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6PTM
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7WP6
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![BU of 7wp6 by Molmil](/molmil-images/mine/7wp6) | Cryo-EM structure of SARS-CoV-2 recombinant spike protein STFK in complex with three neutralizing antibodies | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 36H6 heavy chain, ... | Authors: | Zheng, Q, Sun, H, Yuan, Q, Li, S, Xia, N. | Deposit date: | 2022-01-23 | Release date: | 2023-03-01 | Last modified: | 2023-09-13 | Method: | ELECTRON MICROSCOPY (3.81 Å) | Cite: | Lineage-mosaic and mutation-patched spike proteins for broad-spectrum COVID-19 vaccine. Cell Host Microbe, 30, 2022
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7WP8
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![BU of 7wp8 by Molmil](/molmil-images/mine/7wp8) | Cryo-EM structure of SARS-CoV-2 recombinant spike protein STFK1628x in complex with three neutralizing antibodies | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2B4 heavy chain, ... | Authors: | Zheng, Q, Sun, H, Yuan, Q, Li, S, Xia, N. | Deposit date: | 2022-01-23 | Release date: | 2023-03-08 | Last modified: | 2023-09-13 | Method: | ELECTRON MICROSCOPY (3.88 Å) | Cite: | Lineage-mosaic and mutation-patched spike proteins for broad-spectrum COVID-19 vaccine. Cell Host Microbe, 30, 2022
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6PSO
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![BU of 6pso by Molmil](/molmil-images/mine/6pso) | Crystal structure of PsS1_19B C77S in complex with iota-neocarratetraose | Descriptor: | 3,6-anhydro-2-O-sulfo-alpha-D-galactopyranose-(1-3)-4-O-sulfo-beta-D-galactopyranose-(1-4)-3,6-anhydro-2-O-sulfo-alpha-D-galactopyranose-(1-3)-4-O-sulfo-beta-D-galactopyranose, CALCIUM ION, CHLORIDE ION, ... | Authors: | Hettle, A.G, Boraston, A.B. | Deposit date: | 2019-07-13 | Release date: | 2019-09-25 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Insights into the kappa / iota-carrageenan metabolism pathway of some marinePseudoalteromonasspecies. Commun Biol, 2, 2019
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