3ZJT
| Ternary complex of E.coli leucyl-tRNA synthetase, tRNA(Leu)574 and the benzoxaborole AN3017 in the editing conformation | Descriptor: | LEUCYL-TRNA SYNTHETASE, MAGNESIUM ION, TRNALEU5 UAA ISOACCEPTOR | Authors: | Cusack, S, Palencia, A, Crepin, T, Hernandez, V, Akama, T, Baker, S.J, Bu, W, Feng, L, Freund, Y.R, Liu, L, Meewan, M, Mohan, M, Mao, W, Rock, F.L, Sexton, H, Sheoran, A, Zhang, Y, Zhang, Y, Zhou, Y, Nieman, J.A, Anugula, M.R, Keramane, E.M, Savariraj, K, Reddy, D.S, Sharma, R, Subedi, R, Singh, R, OLeary, A, Simon, N.L, DeMarsh, P.L, Mushtaq, S, Warner, M, Livermore, D.M, Alley, M.R.K, Plattner, J.J. | Deposit date: | 2013-01-18 | Release date: | 2013-04-17 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Discovery of a Novel Class of Boron-Based Antibacterials with Activity Against Gram-Negative Bacteria. Antimicrob.Agents Chemother., 57, 2013
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3ZJU
| Ternary complex of E .coli leucyl-tRNA synthetase, tRNA(Leu) and the benzoxaborole AN3016 in the editing conformation | Descriptor: | LEUCYL-TRNA SYNTHETASE, MAGNESIUM ION, TRNALEU5 UAA ISOACCEPTOR | Authors: | Cusack, S, Palencia, A, Crepin, T, Hernandez, V, Akama, T, Baker, S.J, Bu, W, Feng, L, Freund, Y.R, Liu, L, Meewan, M, Mohan, M, Mao, W, Rock, F.L, Sexton, H, Sheoran, A, Zhang, Y, Zhang, Y, Zhou, Y, Nieman, J.A, Anugula, M.R, Keramane, E.M, Savariraj, K, Reddy, D.S, Sharma, R, Subedi, R, Singh, R, OLeary, A, Simon, N.L, DeMarsh, P.L, Mushtaq, S, Warner, M, Livermore, D.M, Alley, M.R.K, Plattner, J.J. | Deposit date: | 2013-01-18 | Release date: | 2013-04-17 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Discovery of a Novel Class of Boron-Based Antibacterials with Activity Against Gram-Negative Bacteria. Antimicrob.Agents Chemother., 57, 2013
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3ZJV
| Ternary complex of E .coli leucyl-tRNA synthetase, tRNA(Leu) and the benzoxaborole AN3213 in the editing conformation | Descriptor: | LEUCINE--TRNA LIGASE, TRNALEU5 UAA ISOACCEPTOR | Authors: | Cusack, S, Palencia, A, Crepin, T, Hernandez, V, Akama, T, Baker, S.J, Bu, W, Feng, L, Freund, Y.R, Liu, L, Meewan, M, Mohan, M, Mao, W, Rock, F.L, Sexton, H, Sheoran, A, Zhang, Y, Zhang, Y, Zhou, Y, Nieman, J.A, Anugula, M.R, Keramane, E.M, Savariraj, K, Reddy, D.S, Sharma, R, Subedi, R, Singh, R, OLeary, A, Simon, N.L, DeMarsh, P.L, Mushtaq, S, Warner, M, Livermore, D.M, Alley, M.R.K, Plattner, J.J. | Deposit date: | 2013-01-18 | Release date: | 2013-04-17 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2.31 Å) | Cite: | Discovery of a Novel Class of Boron-Based Antibacterials with Activity Against Gram-Negative Bacteria. Antimicrob.Agents Chemother., 57, 2013
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1BK9
| PHOSPHOLIPASE A2 MODIFIED BY PBPB | Descriptor: | 1,4-BUTANEDIOL, CALCIUM ION, PHOSPHOLIPASE A2, ... | Authors: | Zhao, H, Tang, L, Wang, X, Lin, Z, Zhou, Y. | Deposit date: | 1998-07-16 | Release date: | 1999-03-02 | Last modified: | 2023-08-02 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Structure of a snake venom phospholipase A2 modified by p-bromo-phenacyl-bromide. Toxicon, 36, 1998
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1JVM
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2DWD
| crystal structure of KcsA-FAB-TBA complex in Tl+ | Descriptor: | (2S)-3-HYDROXY-2-(NONANOYLOXY)PROPYL LAURATE, ANTIBODY FAB HEAVY CHAIN, ANTIBODY FAB LIGHT CHAIN, ... | Authors: | Yohannan, S, Zhou, Y. | Deposit date: | 2006-08-10 | Release date: | 2007-02-20 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Crystallographic Study of the Tetrabutylammonium Block to the KcsA K(+) Channel J.Mol.Biol., 366, 2007
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2DWE
| Crystal structure of KcsA-FAB-TBA complex in Rb+ | Descriptor: | (2S)-3-HYDROXY-2-(NONANOYLOXY)PROPYL LAURATE, ANTIBODY FAB HEAVY CHAIN, ANTIBODY FAB LIGHT CHAIN, ... | Authors: | Yohannan, S, Zhou, Y. | Deposit date: | 2006-08-10 | Release date: | 2007-02-20 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Crystallographic Study of the Tetrabutylammonium Block to the KcsA K(+) Channel J.Mol.Biol., 366, 2007
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3WQW
| Crystal structure of Ostrinia furnacalis Group I chitinase catalytic domain in complex with a(GlcN)6 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-amino-2-deoxy-beta-D-glucopyranose-(1-4)-2-amino-2-deoxy-beta-D-glucopyranose-(1-4)-2-amino-2-deoxy-beta-D-glucopyranose-(1-4)-2-amino-2-deoxy-beta-D-glucopyranose-(1-4)-2-amino-2-deoxy-beta-D-glucopyranose, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, ... | Authors: | Chen, L, Zhou, Y, Yang, Q. | Deposit date: | 2014-02-03 | Release date: | 2014-05-28 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Fully deacetylated chitooligosaccharides act as efficient glycoside hydrolase family 18 chitinase inhibitors. J.Biol.Chem., 289, 2014
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3WQV
| Crystal structure of Ostrinia furnacalis Group I chitinase catalytic domain in complex with a(GlcN)5 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-amino-2-deoxy-beta-D-glucopyranose-(1-4)-2-amino-2-deoxy-beta-D-glucopyranose-(1-4)-2-amino-2-deoxy-beta-D-glucopyranose-(1-4)-2-amino-2-deoxy-beta-D-glucopyranose-(1-4)-2-amino-2-deoxy-beta-D-glucopyranose, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, ... | Authors: | Chen, L, Zhou, Y, Yang, Q. | Deposit date: | 2014-02-03 | Release date: | 2014-05-28 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.043 Å) | Cite: | Fully deacetylated chitooligosaccharides act as efficient glycoside hydrolase family 18 chitinase inhibitors. J.Biol.Chem., 289, 2014
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1KGS
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3OOS
| The structure of an alpha/beta fold family hydrolase from Bacillus anthracis str. Sterne | Descriptor: | Alpha/beta hydrolase family protein, GLYCEROL, SULFATE ION, ... | Authors: | Fan, Y, Tan, K, Bigelow, L, Hamilton, J, Li, H, Zhou, Y, Clancy, S, Buck, K, Joachimiak, A, Midwest Center for Structural Genomics (MCSG) | Deposit date: | 2010-08-31 | Release date: | 2010-11-10 | Last modified: | 2017-11-08 | Method: | X-RAY DIFFRACTION (1.65 Å) | Cite: | The structure of an alpha/beta fold family hydrolase from Bacillus anthracis str. Sterne To be Published
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3OOP
| The structure of a protein with unknown function from Listeria innocua Clip11262 | Descriptor: | Lin2960 protein | Authors: | Fan, Y, Li, H, Zhou, Y, Gu, M, Joachimiak, A, Midwest Center for Structural Genomics (MCSG) | Deposit date: | 2010-08-31 | Release date: | 2010-09-22 | Last modified: | 2017-11-08 | Method: | X-RAY DIFFRACTION (1.78 Å) | Cite: | The structure of a protein with unknown function from Listeria innocua Clip11262 To be Published
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3A8E
| The structure of AxCesD octamer complexed with cellopentaose | Descriptor: | Cellulose synthase operon protein D, beta-D-glucopyranose-(1-4)-beta-D-glucopyranose-(1-4)-beta-D-glucopyranose-(1-4)-beta-D-glucopyranose-(1-4)-beta-D-glucopyranose | Authors: | Hu, S.Q, Tajima, K, Zhou, Y, Yao, M, Tanaka, I. | Deposit date: | 2009-10-05 | Release date: | 2010-09-22 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Structure of bacterial cellulose synthase subunit D octamer with four inner passageways Proc.Natl.Acad.Sci.USA, 107, 2010
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3AJ2
| The structure of AxCeSD octamer (C-terminal HIS-tag) from Acetobacter xylinum | Descriptor: | Cellulose synthase operon protein D | Authors: | Hu, S.Q, Tajima, K, Zhou, Y, Tanaka, I, Yao, M. | Deposit date: | 2010-05-20 | Release date: | 2010-10-06 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Structure of bacterial cellulose synthase subunit D octamer with four inner passageways Proc.Natl.Acad.Sci.USA, 107, 2010
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3AJ1
| The structure of AxCeSD octamer (N-terminal HIS-tag) from Acetobacter xylinum | Descriptor: | Cellulose synthase operon protein D | Authors: | Hu, S.Q, Tajima, K, Zhou, Y, Tanaka, I, Yao, M. | Deposit date: | 2010-05-20 | Release date: | 2010-10-06 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Structure of bacterial cellulose synthase subunit D octamer with four inner passageways Proc.Natl.Acad.Sci.USA, 107, 2010
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3V3M
| Severe Acute Respiratory Syndrome Coronavirus (SARS-CoV) 3CL Protease in Complex with N-[(1R)-2-(tert-butylamino)-2-oxo-1-(pyridin-3-yl)ethyl]-N-(4-tert-butylphenyl)furan-2-carboxamide inhibitor. | Descriptor: | 3C-like proteinase, DIMETHYL SULFOXIDE, N-[(1R)-2-(tert-butylamino)-2-oxo-1-(pyridin-3-yl)ethyl]-N-(4-tert-butylphenyl)furan-2-carboxamide | Authors: | Jacobs, J, Grum-Tokars, V, Zhou, Y, Turlington, M, Saldanha, S.A, Chase, P, Eggler, A, Dawson, E.S, Baez-Santos, Y.M, Tomar, S, Mielech, A.M, Baker, S.C, Lindsley, C.W, Hodder, P, Mesecar, A, Stauffer, S.R. | Deposit date: | 2011-12-13 | Release date: | 2013-01-16 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (1.96 Å) | Cite: | Discovery, Synthesis, And Structure-Based Optimization of a Series of N-(tert-Butyl)-2-(N-arylamido)-2-(pyridin-3-yl) Acetamides (ML188) as Potent Noncovalent Small Molecule Inhibitors of the Severe Acute Respiratory Syndrome Coronavirus (SARS-CoV) 3CL Protease. J.Med.Chem., 56, 2013
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2DGN
| Mouse Muscle Adenylosuccinate Synthetase partially ligated complex with GTP, 2'-deoxy-IMP | Descriptor: | 9-(2-DEOXY-5-O-PHOSPHONO-BETA-D-ERYTHRO-PENTOFURANOSYL)-6-(PHOSPHONOOXY)-9H-PURINE, Adenylosuccinate synthetase isozyme 1, GUANOSINE-5'-DIPHOSPHATE, ... | Authors: | Iancu, C.V, Zhou, Y, Borza, T, Fromm, H.J, Honzatko, R.B. | Deposit date: | 2006-03-15 | Release date: | 2006-09-15 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Cavitation as a mechanism of substrate discrimination by adenylosuccinate synthetases. Biochemistry, 45, 2006
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3VTR
| Crystal Structure of insect beta-N-acetyl-D-hexosaminidase OfHex1 E328A complexed with TMG-chitotriomycin | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-deoxy-2-(trimethylammonio)-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, N-acetylglucosaminidase | Authors: | Liu, T, Zhou, Y, Chen, L, Chen, W, Liu, L, Shen, X, Yang, Q. | Deposit date: | 2012-06-02 | Release date: | 2013-01-16 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Structural insights into cellulolytic and chitinolytic enzymes revealing crucial residues of insect beta-N-acetyl-D-hexosaminidase Plos One, 7, 2012
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3WL0
| Crystal structure of Ostrinia furnacalis Group I chitinase catalytic domain E148A mutant in complex with a(GlcNAc)2 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Chitinase | Authors: | Chen, L, Liu, T, Zhou, Y, Chen, Q, Shen, X, Yang, Q. | Deposit date: | 2013-11-05 | Release date: | 2014-04-09 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.204 Å) | Cite: | Structural characteristics of an insect group I chitinase, an enzyme indispensable to moulting. Acta Crystallogr.,Sect.D, 70, 2014
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6B7N
| Cryo-electron microscopy structure of porcine delta coronavirus spike protein in the pre-fusion state | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | Authors: | Shang, J, Zheng, Y, Yang, Y, Liu, C, Geng, Q, Tai, W, Du, L, Zhou, Y, Zhang, W, Li, F. | Deposit date: | 2017-10-04 | Release date: | 2017-10-25 | Last modified: | 2020-07-29 | Method: | ELECTRON MICROSCOPY (3.3 Å) | Cite: | Cryo-Electron Microscopy Structure of Porcine Deltacoronavirus Spike Protein in the Prefusion State J. Virol., 92, 2018
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3WKZ
| Crystal Structure of the Ostrinia furnacalis Group I Chitinase catalytic domain E148Q mutant | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Chitinase | Authors: | Chen, L, Liu, T, Zhou, Y, Chen, Q, Shen, X, Yang, Q. | Deposit date: | 2013-11-05 | Release date: | 2014-04-09 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.001 Å) | Cite: | Structural characteristics of an insect group I chitinase, an enzyme indispensable to moulting. Acta Crystallogr.,Sect.D, 70, 2014
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3WL1
| Crystal structure of Ostrinia furnacalis Group I chitinase catalytic domain in complex with reaction products (GlcNAc)2,3 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | Authors: | Chen, L, Liu, T, Zhou, Y, Chen, Q, Shen, X, Yang, Q. | Deposit date: | 2013-11-05 | Release date: | 2014-04-09 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (1.772 Å) | Cite: | Structural characteristics of an insect group I chitinase, an enzyme indispensable to moulting. Acta Crystallogr.,Sect.D, 70, 2014
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3WMC
| Crystal structure of insect beta-N-acetyl-D-hexosaminidase OfHex1 complexed with naphthalimide derivative Q2 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 6-(dimethylamino)-2-(2-{[(5-methyl-1,3,4-thiadiazol-2-yl)methyl]amino}ethyl)-1H-benzo[de]isoquinoline-1,3(2H)-dione, Beta-hexosaminidase | Authors: | Chen, L, Zhou, Y, Chen, L, Yang, Q. | Deposit date: | 2013-11-16 | Release date: | 2014-11-05 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.095 Å) | Cite: | A crystal structure-guided rational design switching non-carbohydrate inhibitors' specificity between two beta-GlcNAcase homologs Sci Rep, 4, 2014
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3W4R
| Crystal structure of an insect chitinase from the Asian corn borer, Ostrinia furnacalis | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Chitinase | Authors: | Chen, L, Liu, T, Zhou, Y, Shen, X, Yang, Q. | Deposit date: | 2013-01-10 | Release date: | 2014-02-12 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Structural characteristics of an insect group I chitinase, an enzyme indispensable to moulting Acta Crystallogr.,Sect.D, 70, 2014
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2AY0
| Structure of the Lys9Met mutant of the E. coli Proline Utilization A (PutA) DNA-binding domain. | Descriptor: | Bifunctional putA protein, CHLORIDE ION | Authors: | Larson, J.D, Schuermann, J.P, Zhou, Y, Jenkins, J.L, Becker, D.F, Tanner, J.J. | Deposit date: | 2005-09-06 | Release date: | 2006-08-15 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Crystal structures of the DNA-binding domain of Escherichia coli proline utilization A flavoprotein and analysis of the role of Lys9 in DNA recognition. Protein Sci., 15, 2006
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