6MEP
| Crystal structure of the catalytic domain of the proto-oncogene tyrosine-protein kinase MER in complex with inhibitor UNC3437 | Descriptor: | CHLORIDE ION, MAGNESIUM ION, Tyrosine-protein kinase Mer, ... | Authors: | Da, C, Zhang, D, Stashko, M.A, Cheng, A, Hunter, D, Norris-Drouin, J, Graves, L, Machius, M, Miley, M.J, DeRyckere, D, Earp, H.S, Graham, D.K, Frye, S.V, Wang, X, Kireev, D. | Deposit date: | 2018-09-06 | Release date: | 2019-09-11 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (2.893 Å) | Cite: | Data-Driven Construction of Antitumor Agents with Controlled Polypharmacology. J.Am.Chem.Soc., 141, 2019
|
|
6WZ6
| Complex of mutant (K173M) of Pseudomonas 7A Glutaminase-Asparaginase with L-Glu at pH 5. Covalent acyl-enzyme intermediate | Descriptor: | 1,2-ETHANEDIOL, GLUTAMIC ACID, Glutaminase-asparaginase | Authors: | Strzelczyk, P, Zhang, D, Wlodawer, A, Lubkowski, J. | Deposit date: | 2020-05-13 | Release date: | 2020-10-14 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (1.15 Å) | Cite: | Generalized enzymatic mechanism of catalysis by tetrameric L-asparaginases from mesophilic bacteria. Sci Rep, 10, 2020
|
|
6WYW
| Crystal structure of Pseudomonas 7A Glutaminase-Asparaginase in complex with L-Asp at pH 4.5 | Descriptor: | ASPARTIC ACID, Glutaminase-asparaginase | Authors: | Strzelczyk, P, Zhang, D, Wlodawer, A, Lubkowski, J. | Deposit date: | 2020-05-13 | Release date: | 2020-10-14 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (2.13 Å) | Cite: | Generalized enzymatic mechanism of catalysis by tetrameric L-asparaginases from mesophilic bacteria. Sci Rep, 10, 2020
|
|
6WYX
| Crystal structure of Pseudomonas 7A Glutaminase-Asparaginase in complex with L-Asp at pH 5.0 | Descriptor: | ASPARTIC ACID, GLYCEROL, Glutaminase-asparaginase | Authors: | Strzelczyk, P, Zhang, D, Wlodawer, A, Lubkowski, J. | Deposit date: | 2020-05-13 | Release date: | 2020-10-14 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (1.48 Å) | Cite: | Generalized enzymatic mechanism of catalysis by tetrameric L-asparaginases from mesophilic bacteria. Sci Rep, 10, 2020
|
|
6K7T
| Crystal structure of bat (Pteropus Alecto) MHC class I Ptal-N*01:01 in complex with Hendra virus-derived peptide HeV1--human beta-2 microglobulin | Descriptor: | Beta-2-microglobulin, HeV1, MHC class I antigen | Authors: | Lu, D, Liu, K.F, Zhang, D, Yue, C, Lu, Q, Cheng, H, Chai, Y, Qi, J.X, Gao, F.G, Liu, W.J. | Deposit date: | 2019-06-08 | Release date: | 2019-11-06 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Peptide presentation by bat MHC class I provides new insight into the antiviral immunity of bats. Plos Biol., 17, 2019
|
|
6K7U
| Crystal structure of beta-2 microglobulin (beta2m) of Bat (Pteropus Alecto) | Descriptor: | Bat beta-2-microglobulin | Authors: | Lu, D, Liu, K.F, Zhang, D, Yue, C, Lu, Q, Cheng, H, Chai, Y, Qi, J.X, Gao, F.G, Liu, W.J. | Deposit date: | 2019-06-08 | Release date: | 2019-09-18 | Last modified: | 2019-12-04 | Method: | X-RAY DIFFRACTION (1.601 Å) | Cite: | Peptide presentation by bat MHC class I provides new insight into the antiviral immunity of bats. Plos Biol., 17, 2019
|
|
2HNG
| The Crystal Structure of Protein of Unknown Function SP1558 from Streptococcus pneumoniae | Descriptor: | Hypothetical protein | Authors: | Kim, Y, Zhang, D, Zhou, M, Clancy, S, Joachimiak, A, Midwest Center for Structural Genomics (MCSG) | Deposit date: | 2006-07-12 | Release date: | 2006-08-15 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (1.63 Å) | Cite: | The Crystal Structure of Hypothetical Protein SP_1558 from Streptococcus pneumoniae To be Published, 2006
|
|
5U8T
| Structure of Eukaryotic CMG Helicase at a Replication Fork and Implications | Descriptor: | Cell division control protein 45, DNA (5'-D(P*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*T)-3'), DNA replication complex GINS protein PSF1, ... | Authors: | Li, B, Georgescu, R, Yuan, Z, Santos, R, Sun, J, Zhang, D, Yurieva, O, Li, H, O'Donnell, M.E. | Deposit date: | 2016-12-15 | Release date: | 2017-02-08 | Last modified: | 2019-12-18 | Method: | ELECTRON MICROSCOPY (4.9 Å) | Cite: | Structure of eukaryotic CMG helicase at a replication fork and implications to replisome architecture and origin initiation. Proc. Natl. Acad. Sci. U.S.A., 114, 2017
|
|
5U8S
| Structure of eukaryotic CMG helicase at a replication fork | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, Cell division control protein 45, DNA (26-MER), ... | Authors: | Li, H, Li, B, Georgescu, R, Yuan, Z, Santos, R, Sun, J, Zhang, D, Yurieva, O, O'Donnell, M.E. | Deposit date: | 2016-12-14 | Release date: | 2017-01-25 | Last modified: | 2020-01-01 | Method: | ELECTRON MICROSCOPY (6.101 Å) | Cite: | Structure of eukaryotic CMG helicase at a replication fork and implications to replisome architecture and origin initiation. Proc. Natl. Acad. Sci. U.S.A., 114, 2017
|
|
6M1H
| CryoEM structure of human PAC1 receptor in complex with maxadilan | Descriptor: | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(s) subunit alpha isoforms short, ... | Authors: | Song, X, Wang, J, Zhang, D, Wang, H.W, Ma, Y. | Deposit date: | 2020-02-26 | Release date: | 2020-03-11 | Last modified: | 2020-05-27 | Method: | ELECTRON MICROSCOPY (3.6 Å) | Cite: | Cryo-EM structures of PAC1 receptor reveal ligand binding mechanism. Cell Res., 30, 2020
|
|
6M1I
| CryoEM structure of human PAC1 receptor in complex with PACAP38 | Descriptor: | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(s) subunit alpha isoforms short, ... | Authors: | Song, X, Wang, J, Zhang, D, Wang, H.W, Ma, Y. | Deposit date: | 2020-02-26 | Release date: | 2020-03-11 | Last modified: | 2020-05-27 | Method: | ELECTRON MICROSCOPY (3.5 Å) | Cite: | Cryo-EM structures of PAC1 receptor reveal ligand binding mechanism. Cell Res., 30, 2020
|
|
6J23
| Crystal structure of arabidopsis ADAL complexed with GMP | Descriptor: | Adenosine/AMP deaminase family protein, GUANOSINE-5'-MONOPHOSPHATE, ZINC ION | Authors: | Wu, B.X, Zhang, D, Nie, H.B, Shen, S.L, Li, S.S, Patel, D.J. | Deposit date: | 2018-12-30 | Release date: | 2019-02-27 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Structure ofArabidopsis thaliana N6-methyl-AMP deaminase ADAL with bound GMP and IMP and implications forN6-methyl-AMP recognition and processing. Rna Biol., 16, 2019
|
|
6J4T
| Crystal structure of arabidopsis ADAL complexed with IMP | Descriptor: | Adenosine/AMP deaminase family protein, INOSINIC ACID, ZINC ION | Authors: | Wu, B.X, Zhang, D, Nie, H.B, Shen, S.L, Li, S.S, Patel, D.J. | Deposit date: | 2019-01-10 | Release date: | 2019-07-31 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (1.82 Å) | Cite: | Structure ofArabidopsis thaliana N6-methyl-AMP deaminase ADAL with bound GMP and IMP and implications forN6-methyl-AMP recognition and processing. Rna Biol., 16, 2019
|
|
6IS9
| Crystal Structure of ZmMOC1 | Descriptor: | Monokaryotic chloroplast 1 | Authors: | Lin, Z, Lin, H, Zhang, D, Yuan, C. | Deposit date: | 2018-11-15 | Release date: | 2019-10-23 | Last modified: | 2024-03-27 | Method: | X-RAY DIFFRACTION (1.86 Å) | Cite: | Structural basis of sequence-specific Holliday junction cleavage by MOC1. Nat.Chem.Biol., 15, 2019
|
|
6JRG
| Crystal structure of ZmMoc1 H253A mutant in complex with Holliday junction | Descriptor: | DNA (32-MER), DNA (33-MER), MAGNESIUM ION, ... | Authors: | Lin, Z, Lin, H, Zhang, D, Yuan, C. | Deposit date: | 2019-04-03 | Release date: | 2019-10-23 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.005 Å) | Cite: | Structural basis of sequence-specific Holliday junction cleavage by MOC1. Nat.Chem.Biol., 15, 2019
|
|
6IS8
| Crystal structure of ZmMoc1 D115N mutant in complex with Holliday junction | Descriptor: | DNA (33-MER), MAGNESIUM ION, Monokaryotic chloroplast 1, ... | Authors: | Lin, Z, Lin, H, Zhang, D, Yuan, C. | Deposit date: | 2018-11-15 | Release date: | 2019-10-23 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (1.68 Å) | Cite: | Structural basis of sequence-specific Holliday junction cleavage by MOC1. Nat.Chem.Biol., 15, 2019
|
|
6JRF
| Crystal structure of ZmMoc1-Holliday junction Complex in the presence of Calcium | Descriptor: | CALCIUM ION, DNA (33-MER), Monokaryotic chloroplast 1, ... | Authors: | Lin, Z, Lin, H, Zhang, D, Yuan, C. | Deposit date: | 2019-04-03 | Release date: | 2019-10-23 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.047 Å) | Cite: | Structural basis of sequence-specific Holliday junction cleavage by MOC1. Nat.Chem.Biol., 15, 2019
|
|
6IV5
| Crystal structure of arabidopsis N6-mAMP deaminase MAPDA | Descriptor: | Adenosine/AMP deaminase family protein, PHOSPHATE ION, ZINC ION | Authors: | Wu, B.X, Zhang, D, Nie, H.B, Shen, S.L, Li, S.S, Patel, D.J. | Deposit date: | 2018-12-02 | Release date: | 2019-02-27 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (1.749 Å) | Cite: | Structure ofArabidopsis thaliana N6-methyl-AMP deaminase ADAL with bound GMP and IMP and implications forN6-methyl-AMP recognition and processing. Rna Biol., 16, 2019
|
|
7F6H
| Cryo-EM structure of human bradykinin receptor BK2R in complex Gq proteins and bradykinin | Descriptor: | Bradykinin, Bradykinin receptor BK2R, CHOLESTEROL, ... | Authors: | Shen, J, Zhang, D, Fu, Y, Chen, A, Zhang, H. | Deposit date: | 2021-06-25 | Release date: | 2022-01-05 | Last modified: | 2023-01-18 | Method: | ELECTRON MICROSCOPY (2.9 Å) | Cite: | Cryo-EM structures of human bradykinin receptor-G q proteins complexes. Nat Commun, 13, 2022
|
|
7F6I
| Cryo-EM structure of human bradykinin receptor BK2R in complex Gq proteins and kallidin | Descriptor: | Bradykinin receptor BK2R, CHOLESTEROL, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... | Authors: | Shen, J, Zhang, D, Fu, Y, Chen, A, Zhang, H. | Deposit date: | 2021-06-25 | Release date: | 2022-01-05 | Last modified: | 2023-01-18 | Method: | ELECTRON MICROSCOPY (2.8 Å) | Cite: | Cryo-EM structures of human bradykinin receptor-G q proteins complexes. Nat Commun, 13, 2022
|
|
8HHK
| |
8HHI
| |
7XA7
| Crystal structure of SARS-CoV-2 receptor-binding domain in complex with intermediate horseshoe bat ACE2 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Angiotensin-converting enzyme, Spike protein S1, ... | Authors: | Tang, L.F, Zhang, D, Han, P, Qi, J.X. | Deposit date: | 2022-03-17 | Release date: | 2022-12-21 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (3.31 Å) | Cite: | Structural basis of SARS-CoV-2 and its variants binding to intermediate horseshoe bat ACE2. Int J Biol Sci, 18, 2022
|
|
2LZ5
| Solution structure of a Novel Alpha-Conotoxin TxIB | Descriptor: | Conotoxin_TxIB | Authors: | Luo, S, Zhangsun, D, Wu, Y, Zhu, X, Hu, Y, McIntyre, M, Christensen, S, Akcan, M, Craik, D, McIntosh, J. | Deposit date: | 2012-09-23 | Release date: | 2012-12-05 | Last modified: | 2023-06-14 | Method: | SOLUTION NMR | Cite: | Characterization of a novel alpha-conotoxin from conus textile that selectively targets alpha6/alpha3beta2beta3 nicotinic acetylcholine receptors. J.Biol.Chem., 288, 2013
|
|
2M3I
| Characterization of a Novel Alpha4/6-Conotoxin TxIC from Conus textile that Potently Blocks alpha3beta4 Nicotinic Acetylcholine Receptors | Descriptor: | Alpha-conotoxin | Authors: | Luo, S, Zhangsun, D, Zhu, X, Wu, Y, Hu, Y, Christensen, S, Akcan, M, Craik, D.J, McIntosh, J.M. | Deposit date: | 2013-01-20 | Release date: | 2013-12-04 | Last modified: | 2023-06-14 | Method: | SOLUTION NMR | Cite: | Characterization of a Novel alpha-Conotoxin TxID from Conus textile That Potently Blocks Rat alpha 3 beta 4 Nicotinic Acetylcholine Receptors. J.Med.Chem., 56, 2013
|
|