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5NJ3
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BU of 5nj3 by Molmil
Structure of an ABC transporter: complete structure
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 5D3-Fab heavy chain, 5D3-Fab light chain, ...
Authors:Taylor, N.M.I, Manolaridis, I, Jackson, S.M, Kowal, J, Stahlberg, H, Locher, K.P.
Deposit date:2017-03-28
Release date:2017-06-07
Last modified:2020-07-29
Method:ELECTRON MICROSCOPY (3.78 Å)
Cite:Structure of the human multidrug transporter ABCG2.
Nature, 546, 2017
5M2Q
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BU of 5m2q by Molmil
Structure of cobinamide-bound BtuF mutant W66F, the periplasmic vitamin B12 binding protein in E.coli
Descriptor: COB(II)INAMIDE, CYANIDE ION, GLYCEROL, ...
Authors:Mireku, S.A, Ruetz, M, Zhou, T, Korkhov, V.M, Kraeutler, B, Locher, K.P.
Deposit date:2016-10-13
Release date:2017-03-01
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Conformational Change of a Tryptophan Residue in BtuF Facilitates Binding and Transport of Cobinamide by the Vitamin B12 Transporter BtuCD-F.
Sci Rep, 7, 2017
5NSA
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BU of 5nsa by Molmil
Beta domain of human transcobalamin bound to Co-beta-[2-(2,4-difluorophenyl)ethinyl]cobalamin
Descriptor: 1-ethynyl-2,4-difluorobenzene, CALCIUM ION, COBALAMIN, ...
Authors:Bloch, J.S, Ruetz, M, Krautler, B, Locher, K.P.
Deposit date:2017-04-25
Release date:2017-09-27
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (1.273 Å)
Cite:Structure of the human transcobalamin beta domain in four distinct states.
PLoS ONE, 12, 2017
5M29
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BU of 5m29 by Molmil
Structure of cobinamide-bound BtuF, the periplasmic vitamin B12 binding protein in E.coli
Descriptor: COB(II)INAMIDE, CYANIDE ION, GLYCEROL, ...
Authors:Mireku, S.A, Ruetz, M, Zhou, T, Korkhov, V.M, Kraeutler, B, Locher, K.P.
Deposit date:2016-10-12
Release date:2017-02-08
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Conformational Change of a Tryptophan Residue in BtuF Facilitates Binding and Transport of Cobinamide by the Vitamin B12 Transporter BtuCD-F.
Sci Rep, 7, 2017
5M3B
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BU of 5m3b by Molmil
Structure of cobinamide-bound BtuF mutant W66L, the periplasmic vitamin B12 binding protein in E.coli
Descriptor: COB(II)INAMIDE, CYANIDE ION, GLYCEROL, ...
Authors:Mireku, S.A, Ruetz, M, Zhou, T, Korkhov, V.M, Kraeutler, B, Locher, K.P.
Deposit date:2016-10-14
Release date:2017-03-01
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Conformational Change of a Tryptophan Residue in BtuF Facilitates Binding and Transport of Cobinamide by the Vitamin B12 Transporter BtuCD-F.
Sci Rep, 7, 2017
5M34
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BU of 5m34 by Molmil
Structure of cobinamide-bound BtuF mutant W66Y, the periplasmic vitamin B12 binding protein in E.coli
Descriptor: COB(II)INAMIDE, CYANIDE ION, GLYCEROL, ...
Authors:Mireku, S.A, Ruetz, M, Zhou, T, Korkhov, V.M, Kraeutler, B, Locher, K.P.
Deposit date:2016-10-14
Release date:2017-03-01
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Conformational Change of a Tryptophan Residue in BtuF Facilitates Binding and Transport of Cobinamide by the Vitamin B12 Transporter BtuCD-F.
Sci Rep, 7, 2017
5OGL
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BU of 5ogl by Molmil
Structure of bacterial oligosaccharyltransferase PglB in complex with an acceptor peptide and an lipid-linked oligosaccharide analog
Descriptor: MANGANESE (II) ION, SODIUM ION, Substrate mimicking peptide, ...
Authors:Napiorkowska, M, Boilevin, J, Sovdat, T, Darbre, T, Reymond, J.-L, Aebi, M, Locher, K.P.
Deposit date:2017-07-13
Release date:2017-10-25
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Molecular basis of lipid-linked oligosaccharide recognition and processing by bacterial oligosaccharyltransferase.
Nat. Struct. Mol. Biol., 24, 2017
6QEE
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BU of 6qee by Molmil
Nanodisc reconstituted Human-mouse chimeric ABCB1 (ABCB1HM)-EQ mutant in complex with UIC2 Fab and Zosuquidar.
Descriptor: 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOETHANOLAMINE, 2-acetamido-2-deoxy-beta-D-glucopyranose, ABCB1HM-EQ, ...
Authors:Alam, A.
Deposit date:2019-01-07
Release date:2019-02-27
Last modified:2021-06-02
Method:ELECTRON MICROSCOPY (3.9 Å)
Cite:Structural insight into substrate and inhibitor discrimination by human P-glycoprotein.
Science, 363, 2019
7NEZ
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BU of 7nez by Molmil
Structure of topotecan-bound ABCG2
Descriptor: (S)-10-[(DIMETHYLAMINO)METHYL]-4-ETHYL-4,9-DIHYDROXY-1H-PYRANO[3',4':6,7]INOLIZINO[1,2-B]-QUINOLINE-3,14(4H,12H)-DIONE, 2-acetamido-2-deoxy-beta-D-glucopyranose, 5D3(Fab) heavy chain variable domain, ...
Authors:Kowal, J, Locher, K, Ni, D, Stahlberg, H.
Deposit date:2021-02-05
Release date:2021-04-21
Last modified:2021-05-12
Method:ELECTRON MICROSCOPY (3.39 Å)
Cite:Structural Basis of Drug Recognition by the Multidrug Transporter ABCG2.
J.Mol.Biol., 433, 2021
7NFD
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BU of 7nfd by Molmil
Structure of mitoxantrone-bound ABCG2
Descriptor: 1,4-DIHYDROXY-5,8-BIS({2-[(2-HYDROXYETHYL)AMINO]ETHYL}AMINO)-9,10-ANTHRACENEDIONE, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 5D3(Fab) heavy chain variable domain, ...
Authors:Kowal, J, Locher, K, Ni, D, Stahlberg, H.
Deposit date:2021-02-06
Release date:2021-04-21
Last modified:2021-05-12
Method:ELECTRON MICROSCOPY (3.51 Å)
Cite:Structural Basis of Drug Recognition by the Multidrug Transporter ABCG2.
J.Mol.Biol., 433, 2021
7NEQ
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BU of 7neq by Molmil
Structure of tariquidar-bound ABCG2
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 5D3(Fab) heavy chain variable domain, 5D3(Fab) light chain variable domain, ...
Authors:Kowal, J, Locher, K.
Deposit date:2021-02-04
Release date:2021-04-21
Last modified:2021-05-12
Method:ELECTRON MICROSCOPY (3.12 Å)
Cite:Structural Basis of Drug Recognition by the Multidrug Transporter ABCG2.
J.Mol.Biol., 433, 2021

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数据于2024-06-12公开中

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