5M2Q

Structure of cobinamide-bound BtuF mutant W66F, the periplasmic vitamin B12 binding protein in E.coli

Summary for 5M2Q

Entry DOI	10.2210/pdb5m2q/pdb
Related	1N2Z 1N4A 1N4D 5M29
Descriptor	Outer membrane protein A,Vitamin B12-binding protein, COB(II)INAMIDE, CYANIDE ION, ... (5 entities in total)
Functional Keywords	btuf, cobinamide, periplasmic binding protein, abc transporter, transport protein
Biological source	Escherichia coli More
Total number of polymer chains	2
Total formula weight	65254.27
Authors	Mireku, S.A.,Ruetz, M.,Zhou, T.,Korkhov, V.M.,Kraeutler, B.,Locher, K.P. (deposition date: 2016-10-13, release date: 2017-03-01, Last modification date: 2024-01-17)
Primary citation	Mireku, S.A.,Ruetz, M.,Zhou, T.,Korkhov, V.M.,Krautler, B.,Locher, K.P. Conformational Change of a Tryptophan Residue in BtuF Facilitates Binding and Transport of Cobinamide by the Vitamin B12 Transporter BtuCD-F. Sci Rep, 7:41575-41575, 2017 Cited by PubMed: 28128319 DOI: 10.1038/srep41575 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.7 Å)

Structure validation