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2PEI
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BU of 2pei by Molmil
Crystal structure of selenomethionine-labeled RbcX
Descriptor: ORF134
Authors:Saschenbrecker, S, Bracher, A, Vasudeva Rao, K, Vasudeva Rao, B, Hartl, F.U, Hayer-Hartl, M.
Deposit date:2007-04-03
Release date:2007-07-10
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Structure and Function of RbcX, an Assembly Chaperone for Hexadecameric Rubisco.
Cell(Cambridge,Mass.), 129, 2007
2HW8
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BU of 2hw8 by Molmil
Structure of ribosomal protein L1-mRNA complex at 2.1 resolution.
Descriptor: 1,4-BUTANEDIOL, 36-MER, 50S ribosomal protein L1, ...
Authors:Tishchenko, S, Nikonova, E, Nikulin, A, Nevskaya, N, Volchkov, S, Piendl, W, Garber, M, Nikonov, S.
Deposit date:2006-08-01
Release date:2006-12-19
Last modified:2024-10-09
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structure of the ribosomal protein L1-mRNA complex at 2.1 A resolution: common features of crystal packing of L1-RNA complexes.
ACTA CRYSTALLOGR.,SECT.D, 62, 2006
1HQ7
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BU of 1hq7 by Molmil
CRYSTALLOGRAPHIC STUDIES OF A DODECAMER B-DNA D-(GCAAACGTTTGC)2
Descriptor: 5'-D(*GP*CP*AP*AP*AP*CP*GP*TP*TP*TP*GP*C)-3'
Authors:Chen, S, Berman, H.M.
Deposit date:2000-12-14
Release date:2003-07-07
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Signatures of protein-DNA recognition in free DNA binding sites.
J.Mol.Biol., 386, 2009
7LSY
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BU of 7lsy by Molmil
NHEJ Short-range synaptic complex
Descriptor: DNA (26-MER), DNA (5'-D(P*CP*AP*AP*TP*GP*AP*AP*AP*CP*GP*GP*AP*AP*CP*AP*GP*TP*CP*AP*G)-3'), DNA (5'-D(P*GP*TP*TP*CP*TP*TP*AP*GP*TP*AP*TP*AP*TP*A)-3'), ...
Authors:He, Y, Chen, S.
Deposit date:2021-02-18
Release date:2021-04-14
Last modified:2023-08-16
Method:ELECTRON MICROSCOPY (8.4 Å)
Cite:Structural basis of long-range to short-range synaptic transition in NHEJ.
Nature, 593, 2021
6LFD
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BU of 6lfd by Molmil
Crystal structure of VMB-1 at pH5.5(Bis-Tris)
Descriptor: GLYCEROL, VMB-1, ZINC ION
Authors:Cheng, Q, Chen, S.
Deposit date:2019-12-02
Release date:2020-02-26
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (1.92 Å)
Cite:Crystal structure of VMB-1 at pH 5.5(Bis-Tris)
To Be Published
6LF4
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BU of 6lf4 by Molmil
Crystal structure of VMB-1 bound to hydrolyzed meropenem
Descriptor: (2~{S},3~{R},4~{S})-2-[(2~{S},3~{R})-1,3-bis(oxidanyl)-1-oxidanylidene-butan-2-yl]-4-[(3~{S},5~{S})-5-(dimethylcarbamoy l)pyrrolidin-3-yl]sulfanyl-3-methyl-3,4-dihydro-2~{H}-pyrrole-5-carboxylic acid, VMB-1 metallo-beta-lactamase, ZINC ION
Authors:Cheng, Q, Chen, S.
Deposit date:2019-11-28
Release date:2020-03-25
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.01 Å)
Cite:Crystal structure of VMB-1 bound to hydrolyzed meropenem
To Be Published
6M3M
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BU of 6m3m by Molmil
Crystal structure of SARS-CoV-2 nucleocapsid protein N-terminal RNA binding domain
Descriptor: Nucleoprotein
Authors:Chen, S, Kang, S.
Deposit date:2020-03-04
Release date:2020-03-18
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Crystal structure of SARS-CoV-2 nucleocapsid protein RNA binding domain reveals potential unique drug targeting sites.
Acta Pharm Sin B, 10, 2020
5VOV
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BU of 5vov by Molmil
Structure of AMPA receptor-TARP complex
Descriptor: Glutamate receptor 2, Voltage-dependent calcium channel gamma-2 subunit
Authors:Zhao, Y, Chen, S, Wang, Y.S, Shekhar, M, Tajkhorshid, E, Gouaux, E.
Deposit date:2017-05-03
Release date:2017-07-12
Last modified:2024-10-30
Method:ELECTRON MICROSCOPY (7.7 Å)
Cite:Activation and Desensitization Mechanism of AMPA Receptor-TARP Complex by Cryo-EM.
Cell, 170, 2017
4JLW
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BU of 4jlw by Molmil
Crystal structure of formaldehyde dehydrogenase from Pseudomonas aeruginosa
Descriptor: Glutathione-independent formaldehyde dehydrogenase, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, SULFATE ION, ...
Authors:Chen, S, Liao, Y.P, Wang, D.L, Wang, S, Ding, J.F, Wang, Y.M, Cai, L.J, Ran, X.Y, Zhu, H.X.
Deposit date:2013-03-13
Release date:2013-10-30
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Structure of formaldehyde dehydrogenase from Pseudomonas aeruginosa: the binary complex with the cofactor NAD+.
Acta Crystallogr.,Sect.F, 69, 2013
2MOA
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BU of 2moa by Molmil
Solution NMR structure of peptide ImI1 (peak 2)
Descriptor: Alpha-conotoxin ImI
Authors:Heinis, C, Chen, S.
Deposit date:2014-04-24
Release date:2014-09-24
Last modified:2023-11-15
Method:SOLUTION NMR
Cite:Dithiol amino acids can structurally shape and enhance the ligand-binding properties of polypeptides.
Nat Chem, 6, 2014
4JK6
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BU of 4jk6 by Molmil
Human urokinase-type Plasminogen Activator (uPA) in complex with a bicyclic peptide inhibitor (UK18-D-Aba)
Descriptor: 1,3,5-tris(bromomethyl)benzene, CHLORIDE ION, HEXAETHYLENE GLYCOL, ...
Authors:Buth, S.A, Leiman, P.G, Chen, S, Heinis, C.
Deposit date:2013-03-09
Release date:2013-07-17
Last modified:2024-07-10
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Improving binding affinity and stability of Peptide ligands by substituting glycines with d-amino acids.
Chembiochem, 14, 2013
4JK5
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BU of 4jk5 by Molmil
Human urokinase-type Plasminogen Activator (uPA) in complex with a bicyclic peptide inhibitor (UK18-D-Ser)
Descriptor: 1,3,5-tris(bromomethyl)benzene, CHLORIDE ION, HEXAETHYLENE GLYCOL, ...
Authors:Buth, S.A, Leiman, P.G, Chen, S, Heinis, C.
Deposit date:2013-03-09
Release date:2013-07-17
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.55 Å)
Cite:Improving binding affinity and stability of Peptide ligands by substituting glycines with d-amino acids.
Chembiochem, 14, 2013
8K1Q
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BU of 8k1q by Molmil
Human TWIK-related acid-sensitive potassium channel TASK3 at pH 6.0, 5 mM KCl and 135 mM NaCl
Descriptor: CHOLESTEROL HEMISUCCINATE, POTASSIUM ION, Potassium channel subfamily K member 9
Authors:Chen, S, Lin, H.
Deposit date:2023-07-11
Release date:2024-04-17
Last modified:2024-05-01
Method:ELECTRON MICROSCOPY (3.68 Å)
Cite:C-type inactivation and proton modulation mechanisms of the TASK3 channel.
Proc.Natl.Acad.Sci.USA, 121, 2024
8K1V
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BU of 8k1v by Molmil
Human TWIK-related acid-sensitive potassium channel TASK3 at pH 7.4, 5 mM KCl and 135 mM NaCl
Descriptor: CHOLESTEROL HEMISUCCINATE, POTASSIUM ION, Potassium channel subfamily K member 9
Authors:Chen, S, Lin, H.
Deposit date:2023-07-11
Release date:2024-04-17
Last modified:2024-05-01
Method:ELECTRON MICROSCOPY (3.48 Å)
Cite:C-type inactivation and proton modulation mechanisms of the TASK3 channel.
Proc.Natl.Acad.Sci.USA, 121, 2024
8K1Z
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BU of 8k1z by Molmil
Human TWIK-related acid-sensitive potassium channel TASK3 at pH 6.0, 200 mM KCl
Descriptor: CHOLESTEROL HEMISUCCINATE, POTASSIUM ION, Potassium channel subfamily K member 9
Authors:Chen, S, Lin, H.
Deposit date:2023-07-11
Release date:2024-04-17
Last modified:2024-05-01
Method:ELECTRON MICROSCOPY (3.41 Å)
Cite:C-type inactivation and proton modulation mechanisms of the TASK3 channel.
Proc.Natl.Acad.Sci.USA, 121, 2024
8K1J
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BU of 8k1j by Molmil
Human TWIK-related acid-sensitive potassium channel TASK3 at pH 7.4,200 mM KCl
Descriptor: CHOLESTEROL HEMISUCCINATE, POTASSIUM ION, Potassium channel subfamily K member 9
Authors:Chen, S, Lin, H.
Deposit date:2023-07-11
Release date:2024-04-17
Last modified:2024-05-01
Method:ELECTRON MICROSCOPY (3 Å)
Cite:C-type inactivation and proton modulation mechanisms of the TASK3 channel.
Proc.Natl.Acad.Sci.USA, 121, 2024
7LT3
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BU of 7lt3 by Molmil
NHEJ Long-range synaptic complex
Descriptor: ADENOSINE-5'-DIPHOSPHATE, DNA (30-MER), DNA (31-MER), ...
Authors:He, Y, Chen, S.
Deposit date:2021-02-18
Release date:2021-04-14
Last modified:2024-03-06
Method:ELECTRON MICROSCOPY (4.6 Å)
Cite:Structural basis of long-range to short-range synaptic transition in NHEJ.
Nature, 593, 2021
2EU8
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BU of 2eu8 by Molmil
Crystal structure of a thermostable mutant of Bacillus subtilis Adenylate Kinase (Q199R)
Descriptor: Adenylate kinase, BIS(ADENOSINE)-5'-PENTAPHOSPHATE, CALCIUM ION, ...
Authors:Chen, S, Shamoo, Y.
Deposit date:2005-10-28
Release date:2006-06-27
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:In vivo molecular evolution reveals biophysical origins of organismal fitness.
Mol.Cell, 22, 2006
6K1M
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BU of 6k1m by Molmil
Engineered form of a putative cystathionine gamma-lyase
Descriptor: Cystathionine gamma-lyase, PYRIDOXAL-5'-PHOSPHATE, PYRUVIC ACID
Authors:Chen, S, Wang, Y.
Deposit date:2019-05-10
Release date:2020-05-13
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.32 Å)
Cite:Structural characterization of cystathionine gamma-lyase smCSE enables aqueous metal quantum dot biosynthesis.
Int.J.Biol.Macromol., 174, 2021
6K1O
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BU of 6k1o by Molmil
Apo form of a putative cystathionine gamma-lyase
Descriptor: Cystathionine gamma-lyase
Authors:Chen, S, Wang, Y.
Deposit date:2019-05-10
Release date:2020-05-13
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.033 Å)
Cite:Structural characterization of cystathionine gamma-lyase smCSE enables aqueous metal quantum dot biosynthesis.
Int.J.Biol.Macromol., 174, 2021
6K1L
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BU of 6k1l by Molmil
E53A mutant of a putative cystathionine gamma-lyase
Descriptor: Cystathionine gamma-lyase, PYRIDOXAL-5'-PHOSPHATE, PYRUVIC ACID
Authors:Chen, S, Wang, Y.
Deposit date:2019-05-10
Release date:2020-05-13
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.46 Å)
Cite:Structural characterization of cystathionine gamma-lyase smCSE enables aqueous metal quantum dot biosynthesis.
Int.J.Biol.Macromol., 174, 2021
6K1N
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BU of 6k1n by Molmil
PLP-bound form of a putative cystathionine gamma-lyase
Descriptor: Cystathionine gamma-lyase, PYRIDOXAL-5'-PHOSPHATE
Authors:Chen, S, Wang, Y.
Deposit date:2019-05-10
Release date:2020-05-13
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.26 Å)
Cite:Structural characterization of cystathionine gamma-lyase smCSE enables aqueous metal quantum dot biosynthesis.
Int.J.Biol.Macromol., 174, 2021
4GLY
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BU of 4gly by Molmil
Human urokinase-type plasminogen activator uPA in complex with the two-disulfide bridge peptide UK504
Descriptor: BICYCLIC PEPTIDE INHIBITOR UK504, CHLORIDE ION, GLYCEROL, ...
Authors:Buth, S.A, Leiman, P.G, Chen, S, Heinis, C.
Deposit date:2012-08-15
Release date:2013-05-15
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (1.518 Å)
Cite:Bicyclic Peptide Ligands Pulled out of Cysteine-Rich Peptide Libraries.
J.Am.Chem.Soc., 135, 2013
7F5F
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BU of 7f5f by Molmil
SARS-CoV-2 ORF8 S84
Descriptor: CALCIUM ION, ORF8 protein
Authors:Chen, S, Zhou, Z, Chen, X.
Deposit date:2021-06-22
Release date:2022-01-19
Last modified:2024-10-30
Method:X-RAY DIFFRACTION (1.62 Å)
Cite:Crystal Structures of Bat and Human Coronavirus ORF8 Protein Ig-Like Domain Provide Insights Into the Diversity of Immune Responses.
Front Immunol, 12, 2021
7CR5
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BU of 7cr5 by Molmil
Complex structure of a human monoclonal antibody with SARS-CoV-2 nucleocapsid protein NTD
Descriptor: Nucleoprotein, ZINC ION, monoclonal antibody chain H, ...
Authors:Chen, S, Kang, S.
Deposit date:2020-08-12
Release date:2021-03-24
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.08 Å)
Cite:A SARS-CoV-2 antibody curbs viral nucleocapsid protein-induced complement hyperactivation.
Nat Commun, 12, 2021

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数据于2024-10-30公开中

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