5MQW
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5mqw by Molmil](/molmil-images/mine/5mqw) | High-speed fixed-target serial virus crystallography | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, CHLORIDE ION, GUANOSINE-5'-TRIPHOSPHATE, ... | Authors: | Roedig, P, Ginn, H.M, Pakendorf, T, Sutton, G, Harlos, K, Walter, T.S, Meyer, J, Fischer, P, Duman, R, Vartiainen, I, Reime, B, Warmer, M, Brewster, A.S, Young, I.D, Michels-Clark, T, Sauter, N.K, Sikorsky, M, Nelson, S, Damiani, D.S, Alonso-Mori, R, Ren, J, Fry, E.E, David, C, Stuart, D.I, Wagner, A, Meents, A. | Deposit date: | 2016-12-21 | Release date: | 2017-06-21 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | High-speed fixed-target serial virus crystallography. Nat. Methods, 14, 2017
|
|
5MUU
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5muu by Molmil](/molmil-images/mine/5muu) | dsRNA bacteriophage phi6 nucleocapsid | Descriptor: | Major inner protein P1, Major outer capsid protein, Packaging enzyme P4 | Authors: | Sun, Z, El Omari, K, Sun, X, Ilca, S.L, Kotecha, A, Stuart, D.I, Poranen, M.M, Huiskonen, J.T. | Deposit date: | 2017-01-14 | Release date: | 2017-03-22 | Last modified: | 2024-05-15 | Method: | ELECTRON MICROSCOPY (4 Å) | Cite: | Double-stranded RNA virus outer shell assembly by bona fide domain-swapping. Nat Commun, 8, 2017
|
|
5FJ6
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5fj6 by Molmil](/molmil-images/mine/5fj6) | Structure of the P2 polymerase inside in vitro assembled bacteriophage phi6 polymerase complex | Descriptor: | MANGANESE (II) ION, RNA-DIRECTED RNA POLYMERASE | Authors: | Ilca, S, Kotecha, A, Sun, X, Poranen, M.P, Stuart, D.I, Huiskonen, J.T. | Deposit date: | 2015-10-06 | Release date: | 2015-11-04 | Last modified: | 2024-05-08 | Method: | ELECTRON MICROSCOPY (7.9 Å) | Cite: | Localized Reconstruction of Subunits from Electron Cryomicroscopy Images of Macromolecular Complexes. Nat.Commun., 6, 2015
|
|
5GKA
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5gka by Molmil](/molmil-images/mine/5gka) | cryo-EM structure of human Aichi virus | Descriptor: | Genome polyprotein, capsid protein VP0, capsid protein VP1 | Authors: | Zhu, L, Wang, X.X, Ren, J.S, Tuthill, T.J, Fry, E.E, Rao, Z.H, Stuart, D.I. | Deposit date: | 2016-07-04 | Release date: | 2016-09-21 | Last modified: | 2024-03-27 | Method: | ELECTRON MICROSCOPY (3.7 Å) | Cite: | Structure of human Aichi virus and implications for receptor binding Nat Microbiol, 1, 2016
|
|
6I2K
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6i2k by Molmil](/molmil-images/mine/6i2k) | Structure of EV71 complexed with its receptor SCARB2 | Descriptor: | 1-(2-aminopyridin-4-yl)-3-[(3S)-5-{4-[(E)-(ethoxyimino)methyl]phenoxy}-3-methylpentyl]imidazolidin-2-one, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | Authors: | Zhou, D, Zhao, Y, Kotecha, A, Fry, E.E, Kelly, J, Wang, X, Rao, Z, Rowlands, D.J, Ren, J, Stuart, D.I. | Deposit date: | 2018-11-01 | Release date: | 2018-11-28 | Last modified: | 2020-07-29 | Method: | ELECTRON MICROSCOPY (3.4 Å) | Cite: | Unexpected mode of engagement between enterovirus 71 and its receptor SCARB2. Nat Microbiol, 4, 2019
|
|
6J7V
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6j7v by Molmil](/molmil-images/mine/6j7v) | |
1MU2
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1mu2 by Molmil](/molmil-images/mine/1mu2) | CRYSTAL STRUCTURE OF HIV-2 REVERSE TRANSCRIPTASE | Descriptor: | GLYCEROL, HIV-2 RT, SULFATE ION | Authors: | Ren, J, Bird, L.E, Chamberlain, P.P, Stewart-Jones, G.B, Stuart, D.I, Stammers, D.K. | Deposit date: | 2002-09-23 | Release date: | 2002-10-30 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2.35 Å) | Cite: | Structure of HIV-2 reverse transcriptase at 2.35-A resolution and the mechanism of resistance to non-nucleoside inhibitors Proc.Natl.Acad.Sci.USA, 99, 2002
|
|
6HY0
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6hy0 by Molmil](/molmil-images/mine/6hy0) | Atomic models of P1, P4 C-terminal fragment and P8 fitted in the bacteriophage phi6 nucleocapsid reconstructed with icosahedral symmetry | Descriptor: | Major Outer Capsid Protein P8, Major inner protein P1, Packaging Enzyme P4 | Authors: | El Omari, K, Ilca, S.L, Stuart, D.I, Huiskonen, J.T. | Deposit date: | 2018-10-18 | Release date: | 2019-06-12 | Last modified: | 2024-05-15 | Method: | ELECTRON MICROSCOPY (3.5 Å) | Cite: | Multiple liquid crystalline geometries of highly compacted nucleic acid in a dsRNA virus. Nature, 570, 2019
|
|
6HRO
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6hro by Molmil](/molmil-images/mine/6hro) | Crystal structure of Ebolavirus glycoprotein in complex with inhibitor 118a | Descriptor: | 1-[2-[4-[4-(4-chlorophenyl)-3-methyl-1~{H}-pyrazol-5-yl]-3-oxidanyl-phenoxy]ethyl]piperidin-1-ium-4-carboxamide, 2-acetamido-2-deoxy-beta-D-glucopyranose, DIMETHYL SULFOXIDE, ... | Authors: | Ren, J, Zhao, Y, Stuart, D.I. | Deposit date: | 2018-09-27 | Release date: | 2019-02-27 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Structure-Based in Silico Screening Identifies a Potent Ebolavirus Inhibitor from a Traditional Chinese Medicine Library. J.Med.Chem., 62, 2019
|
|
6HS4
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6hs4 by Molmil](/molmil-images/mine/6hs4) | Crystal structure of Ebolavirus glycoprotein in complex with inhibitor 118 | Descriptor: | 1-[2-[3-oxidanyl-4-(4-phenyl-1~{H}-pyrazol-5-yl)phenoxy]ethyl]piperidine-4-carboxamide, 2-acetamido-2-deoxy-beta-D-glucopyranose, DIMETHYL SULFOXIDE, ... | Authors: | Ren, J, Zhao, Y, Stuart, D.I. | Deposit date: | 2018-09-28 | Release date: | 2019-02-27 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (2.05 Å) | Cite: | Structure-Based in Silico Screening Identifies a Potent Ebolavirus Inhibitor from a Traditional Chinese Medicine Library. J.Med.Chem., 62, 2019
|
|
1QQP
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1qqp by Molmil](/molmil-images/mine/1qqp) | FOOT-AND-MOUTH DISEASE VIRUS/ OLIGOSACCHARIDE RECEPTOR COMPLEX. | Descriptor: | 2-O-sulfo-alpha-L-gulopyranuronic acid-(1-4)-2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose-(1-4)-2-O-sulfo-alpha-L-idopyranuronic acid-(1-4)-2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose-(1-4)-2-O-sulfo-alpha-L-gulopyranuronic acid, PROTEIN (GENOME POLYPROTEIN) | Authors: | Fry, E.E, Lea, S.M, Jackson, T, Newman, J.W.I, Ellard, F.M, Blakemore, W.E, Abu-Ghazaleh, R, Samuel, A, King, A.M.Q, Stuart, D.I. | Deposit date: | 1999-05-20 | Release date: | 1999-06-18 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | The structure and function of a foot-and-mouth disease virus-oligosaccharide receptor complex. EMBO J., 18, 1999
|
|
1HI8
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1hi8 by Molmil](/molmil-images/mine/1hi8) | RNA dependent RNA polymerase from dsRNA bacteriophage phi6 | Descriptor: | MAGNESIUM ION, P2 PROTEIN | Authors: | Grimes, J.M, Butcher, S.J, Makeyev, E.V, Bamford, D.H, Stuart, D.I. | Deposit date: | 2001-01-03 | Release date: | 2001-03-27 | Last modified: | 2019-09-18 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | A Mechanism for Initiating RNA-Dependent RNA Polymerization Nature, 410, 2001
|
|
6ZFO
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6zfo by Molmil](/molmil-images/mine/6zfo) | Association of two complexes of largely structurally disordered Spike ectodomain with bound EY6A Fab | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, EY6A heavy chain, EY6A light chain, ... | Authors: | Duyvesteyn, H.M.E, Zhou, D, Zhao, Y, Fry, E.E, Ren, J, Stuart, D.I. | Deposit date: | 2020-06-17 | Release date: | 2020-07-08 | Last modified: | 2021-12-22 | Method: | ELECTRON MICROSCOPY (4.4 Å) | Cite: | Structural basis for the neutralization of SARS-CoV-2 by an antibody from a convalescent patient. Nat.Struct.Mol.Biol., 27, 2020
|
|
6Z3K
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6z3k by Molmil](/molmil-images/mine/6z3k) | Structure of protective antibody 38-1-10A Fab | Descriptor: | 1,2-ETHANEDIOL, Heavy chain, Light Chain | Authors: | Zhou, D, Fry, E.E, Ren, J, Stuart, D.I. | Deposit date: | 2020-05-20 | Release date: | 2020-09-02 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Structural and functional analysis of protective antibodies targeting the threefold plateau of enterovirus 71. Nat Commun, 11, 2020
|
|
6Z97
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6z97 by Molmil](/molmil-images/mine/6z97) | Structure of the prefusion SARS-CoV-2 spike glycoprotein | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein,Fibritin | Authors: | Duyvesteyn, H.M.E, Ren, J, Zhao, Y, Zhou, D, Huo, J, Carrique, L, Malinauskas, T, Ruza, R.R, Shah, P.N.M, Fry, E.E, Owens, R, Stuart, D.I. | Deposit date: | 2020-06-03 | Release date: | 2020-07-01 | Last modified: | 2020-09-23 | Method: | ELECTRON MICROSCOPY (3.4 Å) | Cite: | Neutralization of SARS-CoV-2 by Destruction of the Prefusion Spike. Cell Host Microbe, 28, 2020
|
|
6ZDH
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6zdh by Molmil](/molmil-images/mine/6zdh) | SARS-CoV-2 Spike glycoprotein in complex with a neutralizing antibody EY6A Fab | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, EY6A heavy chain, ... | Authors: | Duyvesteyn, H.M.E, Zhou, D, Zhao, Y, Fry, E.E, Ren, J, Stuart, D.I. | Deposit date: | 2020-06-14 | Release date: | 2020-07-01 | Last modified: | 2021-12-22 | Method: | ELECTRON MICROSCOPY (3.7 Å) | Cite: | Structural basis for the neutralization of SARS-CoV-2 by an antibody from a convalescent patient. Nat.Struct.Mol.Biol., 27, 2020
|
|
6Z43
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6z43 by Molmil](/molmil-images/mine/6z43) | Cryo-EM Structure of SARS-CoV-2 Spike : H11-D4 Nanobody Complex | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Nanobody, ... | Authors: | Ruza, R.R, Duyvesteyn, H.M.E, Shah, P, Carrique, L, Ren, J, Malinauskas, T, Zhou, D, Stuart, D.I, Naismith, J.H. | Deposit date: | 2020-05-22 | Release date: | 2020-06-03 | Last modified: | 2020-07-29 | Method: | ELECTRON MICROSCOPY (3.3 Å) | Cite: | Structural basis for a potent neutralising single-domain antibody that blocks SARS-CoV-2 binding to its receptor ACE2 To Be Published
|
|
6ZDG
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6zdg by Molmil](/molmil-images/mine/6zdg) | Association of three complexes of largely structurally disordered Spike ectodomain with bound EY6A Fab | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, EY6A heavy chain, EY6A light chain, ... | Authors: | Duyvesteyn, H.M.E, Zhou, D, Zhao, Y, Fry, E.E, Ren, J, Stuart, D.I. | Deposit date: | 2020-06-14 | Release date: | 2020-07-29 | Last modified: | 2021-12-22 | Method: | ELECTRON MICROSCOPY (4.7 Å) | Cite: | Structural basis for the neutralization of SARS-CoV-2 by an antibody from a convalescent patient. Nat.Struct.Mol.Biol., 27, 2020
|
|
6ZER
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6zer by Molmil](/molmil-images/mine/6zer) | Crystal structure of receptor binding domain of SARS-CoV-2 Spike glycoprotein in complex with EY6A Fab | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, EY6A heavy chain, EY6A light chain, ... | Authors: | Zhou, D, Zhao, Y, Fry, E.E, Ren, J, Stuart, D.I. | Deposit date: | 2020-06-16 | Release date: | 2020-06-24 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (3.8 Å) | Cite: | Structural basis for the neutralization of SARS-CoV-2 by an antibody from a convalescent patient. Nat.Struct.Mol.Biol., 27, 2020
|
|
6ZCZ
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6zcz by Molmil](/molmil-images/mine/6zcz) | Crystal structure of receptor binding domain of SARS-CoV-2 Spike glycoprotein in ternary complex with EY6A Fab and a nanobody. | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, EY6A heavy chain, ... | Authors: | Zhou, D, Zhao, Y, Fry, E.E, Ren, J, Stuart, D.I. | Deposit date: | 2020-06-12 | Release date: | 2020-06-24 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (2.65 Å) | Cite: | Structural basis for the neutralization of SARS-CoV-2 by an antibody from a convalescent patient. Nat.Struct.Mol.Biol., 27, 2020
|
|
1ALC
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1alc by Molmil](/molmil-images/mine/1alc) | |
1HI1
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1hi1 by Molmil](/molmil-images/mine/1hi1) | RNA dependent RNA polymerase from dsRNA bacteriophage phi6 plus bound NTP | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, P2 PROTEIN | Authors: | Grimes, J.M, Butcher, S.J, Makeyev, E.V, Bamford, D.H, Stuart, D.I. | Deposit date: | 2001-01-01 | Release date: | 2001-03-27 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | A Mechanism for Initiating RNA-Dependent RNA Polymerization Nature, 410, 2001
|
|
1HI0
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1hi0 by Molmil](/molmil-images/mine/1hi0) | RNA dependent RNA polymerase from dsRNA bacteriophage phi6 plus initiation complex | Descriptor: | DNA (5'-(*TP*TP*TP*CP*C)-3'), GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ... | Authors: | Grimes, J.M, Butcher, S.J, Makeyev, E.V, Bamford, D.H, Stuart, D.I. | Deposit date: | 2000-12-31 | Release date: | 2001-03-27 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | A Mechanism for Initiating RNA-Dependent RNA Polymerization Nature, 410, 2001
|
|
1MHE
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1mhe by Molmil](/molmil-images/mine/1mhe) | THE HUMAN NON-CLASSICAL MAJOR HISTOCOMPATIBILITY COMPLEX MOLECULE HLA-E | Descriptor: | BETA-2-MICROGLOBULIN, HLA CLASS I HISTOCOMPATIBILITY ANTIGEN HLA-E, PEPTIDE (VMAPRTVLL), ... | Authors: | O'Callaghan, C.A, Tormo, J, Willcox, B.E, Braud, V.B, Jakobsen, B.K, Stuart, D.I, Mcmichael, A.J, Bell, J.I, Jones, E.Y. | Deposit date: | 1998-08-24 | Release date: | 1999-03-23 | Last modified: | 2023-08-09 | Method: | X-RAY DIFFRACTION (2.85 Å) | Cite: | Structural features impose tight peptide binding specificity in the nonclassical MHC molecule HLA-E. Mol.Cell, 1, 1998
|
|
3ME4
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3me4 by Molmil](/molmil-images/mine/3me4) | Crystal structure of mouse RANK | Descriptor: | ACETATE ION, CHLORIDE ION, GLYCEROL, ... | Authors: | Walter, S.W, Liu, C, Zhu, X, Wu, Y, Owens, R.J, Stuart, D.I, Gao, B, Ren, J. | Deposit date: | 2010-03-31 | Release date: | 2010-06-02 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (2.01 Å) | Cite: | Structural and Functional Insights of RANKL-RANK Interaction and Signaling. J.Immunol., 2010
|
|