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8V9R
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BU of 8v9r by Molmil
Cryo-EM Structure of a Proteolytic ClpXP AAA+ Machine Poised to Unfold a Branched-Degron DHFR-ssrA Substrate Bound with MTX
Descriptor: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, ATP-dependent Clp protease ATP-binding subunit ClpX, ...
Authors:Ghanbarpour, A, Sauer, R.T, Davis, J.H.
Deposit date:2023-12-09
Release date:2024-10-16
Method:ELECTRON MICROSCOPY (2.8 Å)
Cite:Cryo-EM structure of a fully-engaged DHFR-ssrA substrate and the AAA+ ClpXP protease
To Be Published
9C87
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BU of 9c87 by Molmil
Cryo-EM Structure of a Proteolytic ClpXP AAA+ Machine Poised to Unfold a Linear-Degron DHFR-ssrA Substrate Bound with MTX
Descriptor: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, ATP-dependent Clp protease ATP-binding subunit ClpX, ...
Authors:Ghanbarpour, A, Sauer, R.T, Davis, J.H.
Deposit date:2024-06-12
Release date:2024-10-16
Method:ELECTRON MICROSCOPY (3.7 Å)
Cite:Cryo-EM Structure of a Proteolytic ClpXP AAA+ Machine Poised to Unfold a Linear-Degron DHFR-ssrA Substrate Bound with MTX
To Be Published
1OU9
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BU of 1ou9 by Molmil
Structure of SspB, a AAA+ protease delivery protein
Descriptor: CALCIUM ION, Stringent starvation protein B homolog
Authors:Levchenko, I, Grant, R.A, Wah, D.A, Sauer, R.T, Baker, T.A.
Deposit date:2003-03-24
Release date:2003-09-23
Last modified:2014-04-30
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structure of a delivery protein for an AAA+ protease in complex with a peptide degradation tag
Mol.Cell, 12, 2003
1OUL
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BU of 1oul by Molmil
Structure of the AAA+ protease delivery protein SspB
Descriptor: Stringent starvation protein B homolog
Authors:Levchenko, I, Grant, R.A, Wah, D.A, Sauer, R.T, Baker, T.A.
Deposit date:2003-03-24
Release date:2003-09-23
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structure of a delivery protein for an AAA+ protease in complex with a peptide degradation tag
Mol.Cell, 12, 2003
1BDT
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BU of 1bdt by Molmil
WILD TYPE GENE-REGULATING PROTEIN ARC/DNA COMPLEX
Descriptor: DNA (5'-D(*AP*AP*TP*GP*AP*TP*AP*GP*AP*AP*GP*CP*AP*CP*TP*CP*TP*AP*CP*TP*AP*T)-3'), DNA (5'-D(*TP*AP*TP*AP*GP*TP*AP*GP*AP*GP*TP*GP*CP*TP*TP*CP*TP*AP*TP*CP*AP*T)-3'), PROTEIN (GENE-REGULATING PROTEIN ARC)
Authors:Schilbach, J.F, Karzai, A.W, Raumann, B.E, Sauer, R.T.
Deposit date:1998-05-11
Release date:1999-02-16
Last modified:2023-08-02
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Origins of DNA-binding specificity: role of protein contacts with the DNA backbone.
Proc.Natl.Acad.Sci.USA, 96, 1999
1Q5Y
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BU of 1q5y by Molmil
Nickel-Bound C-terminal Regulatory Domain of NikR
Descriptor: 1,2-ETHANEDIOL, NICKEL (II) ION, Nickel responsive regulator
Authors:Schreiter, E.R, Sintchak, M.D, Guo, Y, Chivers, P.T, Sauer, R.T, Drennan, C.L.
Deposit date:2003-08-11
Release date:2003-09-30
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:Crystal Structure of the Nickel-Responsive Transcription Factor NikR
Nat.Struct.Biol., 10, 2003
1Q5V
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BU of 1q5v by Molmil
Apo-NikR
Descriptor: Nickel responsive regulator
Authors:Schreiter, E.R, Sintchak, M.D, Guo, Y, Chivers, P.T, Sauer, R.T, Drennan, C.L.
Deposit date:2003-08-11
Release date:2003-09-30
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Crystal Structure of the Nickel-Responsive Transcription Factor NikR
Nat.Struct.Biol., 10, 2003
1QTG
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BU of 1qtg by Molmil
AVERAGED NMR MODEL OF SWITCH ARC, A DOUBLE MUTANT OF ARC REPRESSOR
Descriptor: Transcriptional repressor arc
Authors:Cordes, M.H.J, Walsh, N.P, McKnight, C.J, Sauer, R.T.
Deposit date:1999-06-27
Release date:1999-07-12
Last modified:2024-05-22
Method:SOLUTION NMR
Cite:Evolution of a protein fold in vitro.
Science, 284, 1999
1PAR
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BU of 1par by Molmil
DNA RECOGNITION BY BETA-SHEETS IN THE ARC REPRESSOR-OPERATOR CRYSTAL STRUCTURE
Descriptor: DNA (5'-D(*AP*AP*TP*GP*AP*TP*AP*GP*AP*AP*GP*CP*AP*CP*TP*CP*T P*AP*CP*TP*AP*T)- 3'), DNA (5'-D(*TP*AP*TP*AP*GP*TP*AP*GP*AP*GP*TP*GP*CP*TP*TP*CP*T P*AP*TP*CP*AP*T)- 3'), PROTEIN (ARC REPRESSOR)
Authors:Raumann, B.E, Rould, M.A, Pabo, C.O, Sauer, R.T.
Deposit date:1994-03-22
Release date:1994-07-31
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:DNA recognition by beta-sheets in the Arc repressor-operator crystal structure.
Nature, 367, 1994
1MNT
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BU of 1mnt by Molmil
SOLUTION STRUCTURE OF DIMERIC MNT REPRESSOR (1-76)
Descriptor: MNT REPRESSOR
Authors:Burgering, M.J.M, Boelens, R, Gilbert, D.E, Breg, J.N, Knight, K.L, Sauer, R.T, Kaptein, R.
Deposit date:1994-06-28
Release date:1994-09-30
Last modified:2024-05-22
Method:SOLUTION NMR
Cite:Solution structure of dimeric Mnt repressor (1-76).
Biochemistry, 33, 1994
1MYL
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BU of 1myl by Molmil
SUBSTITUTING HYDROPHOBIC RESIDUES FOR A BURIED SALT BRIDGE ENHANCES PROTEIN STABILITY BUT DOES NOT REDUCE CONFORMATIONAL SPECIFICITY
Descriptor: ARC REPRESSOR
Authors:Schildbach, J.F, Waldburger, C.D, Sauer, R.T.
Deposit date:1994-10-06
Release date:1995-01-26
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Are buried salt bridges important for protein stability and conformational specificity?
Nat.Struct.Biol., 2, 1995
1LLI
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BU of 1lli by Molmil
THE CRYSTAL STRUCTURE OF A MUTANT PROTEIN WITH ALTERED BUT IMPROVED HYDROPHOBIC CORE PACKING
Descriptor: DNA (5'-D(*AP*AP*TP*AP*CP*CP*AP*CP*TP*GP*GP*CP*GP*GP*TP*GP*A P*TP*AP*T)-3'), DNA (5'-D(*TP*AP*TP*AP*TP*CP*AP*CP*CP*GP*CP*CP*AP*GP*TP*GP*G P*TP*AP*T)-3'), PROTEIN (LAMBDA REPRESSOR)
Authors:Lim, W.A, Hodel, A, Sauer, R.T, Richards, F.M.
Deposit date:1994-03-25
Release date:1994-08-31
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:The crystal structure of a mutant protein with altered but improved hydrophobic core packing.
Proc.Natl.Acad.Sci.USA, 91, 1994
1NLA
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BU of 1nla by Molmil
Solution Structure of Switch Arc, a Mutant with 3(10) Helices Replacing a Wild-Type Beta-Ribbon
Descriptor: Transcriptional repressor arc
Authors:Cordes, M.H, Walsh, N.P, McKnight, C.J, Sauer, R.T.
Deposit date:2003-01-06
Release date:2003-03-18
Last modified:2024-05-22
Method:SOLUTION NMR
Cite:Solution structure of Switch Arc, a mutant with 3(10) helices replacing a wild-type beta-ribbon
J.Mol.Biol., 326, 2003
2TBV
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BU of 2tbv by Molmil
STRUCTURE OF TOMATO BUSHY STUNT VIRUS. V. COAT PROTEIN SEQUENCE DETERMINATION AND ITS STRUCTURAL IMPLICATIONS
Descriptor: CALCIUM ION, TOMATO BUSHY STUNT VIRUS
Authors:Harrison, S.C.
Deposit date:1984-06-22
Release date:1984-07-20
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Structure of tomato bushy stunt virus. V. Coat protein sequence determination and its structural implications
J.Mol.Biol., 177, 1984
1SOT
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BU of 1sot by Molmil
Crystal Structure of the DegS stress sensor
Descriptor: Protease degS
Authors:Wilken, C, Kitzing, K, Kurzbauer, R, Ehrmann, M, Clausen, T.
Deposit date:2004-03-15
Release date:2004-06-08
Last modified:2024-10-16
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Crystal structure of the DegS stress sensor: How a PDZ domain recognizes misfolded protein and activates a protease
Cell(Cambridge,Mass.), 117, 2004
3ORC
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BU of 3orc by Molmil
CRYSTAL STRUCTURE OF AN ENGINEERED CRO MONOMER BOUND NONSPECIFICALLY TO DNA
Descriptor: DNA (5'-D(*TP*AP*TP*CP*GP*AP*TP*A)-3'), PROTEIN (CRO REPRESSOR)
Authors:Albright, R.A, Mossing, M.C, Matthews, B.W.
Deposit date:1998-04-23
Release date:1998-12-02
Last modified:2023-08-02
Method:X-RAY DIFFRACTION (3 Å)
Cite:Crystal structure of an engineered Cro monomer bound nonspecifically to DNA: possible implications for nonspecific binding by the wild-type protein.
Protein Sci., 7, 1998
1DU0
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BU of 1du0 by Molmil
ENGRAILED HOMEODOMAIN Q50A VARIANT DNA COMPLEX
Descriptor: DNA (5'-D(*AP*TP*TP*AP*GP*GP*TP*AP*AP*TP*TP*AP*CP*AP*TP*GP*GP*CP*AP*AP*A)-3'), DNA (5'-D(*TP*TP*TP*TP*GP*CP*CP*AP*TP*GP*TP*AP*AP*TP*TP*AP*CP*CP*TP*AP*A)-3'), ENGRAILED HOMEODOMAIN
Authors:Grant, R.A, Rould, M.A, Klemm, J.D, Pabo, C.O.
Deposit date:2000-01-13
Release date:2000-07-31
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2 Å)
Cite:Exploring the role of glutamine 50 in the homeodomain-DNA interface: crystal structure of engrailed (Gln50 --> ala) complex at 2.0 A.
Biochemistry, 39, 2000
1SOZ
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BU of 1soz by Molmil
Crystal Structure of DegS protease in complex with an activating peptide
Descriptor: Protease degS, activating peptide
Authors:Wilken, C, Kitzing, K, Kurzbauer, R, Ehrmann, M, Clausen, T.
Deposit date:2004-03-16
Release date:2004-06-08
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Crystal structure of the DegS stress sensor: How a PDZ domain recognizes misfolded protein and activates a protease
Cell(Cambridge,Mass.), 117, 2004
3KZ0
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BU of 3kz0 by Molmil
MCL-1 complex with MCL-1-specific selected peptide
Descriptor: Induced myeloid leukemia cell differentiation protein Mcl-1, Mcl-1 specific peptide MB7, SULFATE ION, ...
Authors:Dutta, S, Fire, E, Grant, R.A, Sauer, R.T, Keating, A.E.
Deposit date:2009-12-07
Release date:2010-05-05
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.349 Å)
Cite:Determinants of BH3 binding specificity for Mcl-1 versus Bcl-xL.
J.Mol.Biol., 398, 2010
1VCW
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BU of 1vcw by Molmil
Crystal structure of DegS after backsoaking the activating peptide
Descriptor: Protease degS
Authors:Wilken, C, Kitzing, K, Kurzbauer, R, Ehrmann, M, Clausen, T.
Deposit date:2004-03-16
Release date:2004-06-08
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (3.05 Å)
Cite:Crystal structure of the DegS stress sensor: How a PDZ domain recognizes misfolded protein and activates a protease.
Cell(Cambridge,Mass.), 117, 2004
2ORC
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BU of 2orc by Molmil
CRO REPRESSOR INSERTION MUTANT K56-[DGEVK], NMR, 32 STRUCTURES
Descriptor: CRO REPRESSOR
Authors:Mossing, M.C.
Deposit date:1998-01-20
Release date:1998-05-27
Last modified:2024-05-22
Method:SOLUTION NMR
Cite:Solution structure and dynamics of a designed monomeric variant of the lambda Cro repressor.
Protein Sci., 7, 1998
1ORC
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BU of 1orc by Molmil
CRO REPRESSOR INSERTION MUTANT K56-[DGEVK]
Descriptor: CRO REPRESSOR INSERTION MUTANT K56-[DGEVK]
Authors:Albright, R.A, Mossing, M.C, Matthews, B.W.
Deposit date:1995-10-30
Release date:1996-12-23
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (1.54 Å)
Cite:High-resolution structure of an engineered Cro monomer shows changes in conformation relative to the native dimer.
Biochemistry, 35, 1996
1LRP
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BU of 1lrp by Molmil
COMPARISON OF THE STRUCTURES OF CRO AND LAMBDA REPRESSOR PROTEINS FROM BACTERIOPHAGE LAMBDA
Descriptor: LAMBDA REPRESSOR
Authors:Pabo, C, Lewis, M.
Deposit date:1987-12-04
Release date:1989-01-09
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Comparison of the structures of cro and lambda repressor proteins from bacteriophage lambda.
J.Mol.Biol., 169, 1983
1LMB
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BU of 1lmb by Molmil
REFINED 1.8 ANGSTROM CRYSTAL STRUCTURE OF THE LAMBDA REPRESSOR-OPERATOR COMPLEX
Descriptor: DNA (5'-D(*AP*AP*TP*AP*CP*CP*AP*CP*TP*GP*GP*CP*GP*GP*TP*GP*A P*TP*AP*T)-3'), DNA (5'-D(*TP*AP*TP*AP*TP*CP*AP*CP*CP*GP*CP*CP*AP*GP*TP*GP*G P*TP*AP*T)-3'), PROTEIN (LAMBDA REPRESSOR)
Authors:Beamer, L.J, Pabo, C.O.
Deposit date:1991-11-05
Release date:1991-11-05
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Refined 1.8 A crystal structure of the lambda repressor-operator complex.
J.Mol.Biol., 227, 1992

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