3LEO
 
 | | Structure of human Leukotriene C4 synthase mutant R31Q in complex with glutathione | | Descriptor: | DODECYL-BETA-D-MALTOSIDE, GLUTATHIONE, GLYCEROL, ... | | Authors: | Niegowski, D, Martinez-Molina, D, Rinaldo-Matthis, A, Nordlund, P, Haeggstrom, J. | | Deposit date: | 2010-01-15 | | Release date: | 2010-10-27 | | Last modified: | 2023-09-06 | | Method: | X-RAY DIFFRACTION (2.1 Å) | | Cite: | Arginine 104 is a key catalytic residue in leukotriene C4 synthase.
J.Biol.Chem., 285, 2010
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2LEZ
 | | Solution NMR structure of N-terminal domain of Salmonella effector protein PipB2. Northeast structural genomics consortium (NESG) target stt318a | | Descriptor: | Secreted effector protein pipB2 | | Authors: | Lemak, A, Yee, A, Houliston, S, Garcia, M, Daniels, C, Savchenko, A, Arrowsmith, C, Montelione, G.T, Northeast Structural Genomics Consortium (NESG) | | Deposit date: | 2011-06-27 | | Release date: | 2011-07-27 | | Last modified: | 2024-05-01 | | Method: | SOLUTION NMR | | Cite: | NMR solution structure of N-terminal domain of Salmonella effector protein PipB2
To be Published
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3LR8
 | | Self-assembly of spider silk proteins is controlled by a pH-sensitive relay | | Descriptor: | 1,2-ETHANEDIOL, DI(HYDROXYETHYL)ETHER, Major ampullate spidroin 1, ... | | Authors: | Askarieh, G, Hedhammar, H, Nordling, K, Rising, A, Johansson, J, Knight, S.D. | | Deposit date: | 2010-02-10 | | Release date: | 2010-05-12 | | Last modified: | 2024-04-03 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | Self-assembly of spider silk proteins is controlled by a pH-sensitive relay.
Nature, 465, 2010
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2P06
 | | Crystal structure of a predicted coding region AF_0060 from Archaeoglobus fulgidus DSM 4304 | | Descriptor: | GLYCEROL, Hypothetical protein AF_0060, MAGNESIUM ION | | Authors: | Nocek, B, Xu, X, Koniyenko, Y, Yakounine, A, Savchenko, A, Edwards, A, Joachimiak, A, Midwest Center for Structural Genomics (MCSG) | | Deposit date: | 2007-02-28 | | Release date: | 2007-03-27 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (2.1 Å) | | Cite: | Crystal structure of a predicted coding region AF_0060 from Archaeoglobus fulgidus DSM 4304
To be Published
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2CSD
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2LBU
 | | HADDOCK calculated model of Congo red bound to the HET-s amyloid | | Descriptor: | Small s protein, sodium 3,3'-(1E,1'E)-biphenyl-4,4'-diylbis(diazene-2,1-diyl)bis(4-aminonaphthalene-1-sulfonate) | | Authors: | Schutz, A.K, Soragni, A, Hornemann, S, Aguzzi, A, Ernst, M, Bockmann, A, Meier, B.H. | | Deposit date: | 2011-04-07 | | Release date: | 2011-06-01 | | Last modified: | 2024-05-01 | | Method: | SOLID-STATE NMR | | Cite: | The Amyloid-Congo Red Interface at Atomic Resolution.
Angew.Chem.Int.Ed.Engl., 2011
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3S9X
 | | High resolution crystal structure of ASCH domain from Lactobacillus crispatus JV V101 | | Descriptor: | ASCH domain, CHLORIDE ION | | Authors: | Nocek, B, Xu, X, Cui, H, Jedrzejczak, R, Edwards, A, Savchenko, A, Mabbutt, B.C, Joachimiak, A, Midwest Center for Structural Genomics (MCSG) | | Deposit date: | 2011-06-02 | | Release date: | 2011-07-27 | | Method: | X-RAY DIFFRACTION (1.35 Å) | | Cite: | High resolution crystal structure of ASCH domain from Lactobacillus crispatus JV V101
TO BE PUBLISHED
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2P5X
 | | Crystal structure of Maf domain of human N-acetylserotonin O-methyltransferase-like protein | | Descriptor: | N-acetylserotonin O-methyltransferase-like protein, PHOSPHATE ION | | Authors: | Min, J, Wu, H, Dombrovski, L, Loppnau, P, Weigelt, J, Sundstrom, M, Arrowsmith, C.H, Edwards, A.M, Bochkarev, A, Plotnikov, A.N, Structural Genomics Consortium (SGC) | | Deposit date: | 2007-03-16 | | Release date: | 2007-03-27 | | Last modified: | 2023-08-30 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Biochemical and structural studies of conserved maf proteins revealed nucleotide pyrophosphatases with a preference for modified nucleotides.
Chem.Biol., 20, 2013
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3DCA
 | | Crystal structure of the RPA0582- protein of unknown function from Rhodopseudomonas palustris- a structural genomics target | | Descriptor: | RPA0582, SULFATE ION | | Authors: | Sledz, P, Wang, S, Chruszcz, M, Yim, V, Kudritska, M, Evdokimova, E, Turk, D, Savchenko, A, Edwards, A, Joachimiak, A, Minor, W, Midwest Center for Structural Genomics (MCSG) | | Deposit date: | 2008-06-03 | | Release date: | 2008-08-05 | | Last modified: | 2022-04-13 | | Method: | X-RAY DIFFRACTION (3.35 Å) | | Cite: | Crystal structure of the RPA0582- protein of unknown function from Rhodopseudomonas palustris- a structural genomics target
To be Published
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1BGK
 | | SEA ANEMONE TOXIN (BGK) WITH HIGH AFFINITY FOR VOLTAGE DEPENDENT POTASSIUM CHANNEL, NMR, 15 STRUCTURES | | Descriptor: | BGK | | Authors: | Dauplais, M, Lecoq, A, Song, J, Cotton, J, Jamin, N, Gilquin, B, Roumestand, C, Vita, C, Harvey, A, Menez, A. | | Deposit date: | 1996-05-08 | | Release date: | 1997-01-27 | | Last modified: | 2022-02-16 | | Method: | SOLUTION NMR | | Cite: | On the convergent evolution of animal toxins. Conservation of a diad of functional residues in potassium channel-blocking toxins with unrelated structures.
J.Biol.Chem., 272, 1997
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3B1K
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2CSB
 | | Crystal structure of Topoisomerase V from Methanopyrus kandleri (61 kDa fragment) | | Descriptor: | MAGNESIUM ION, Topoisomerase V | | Authors: | Taneja, B, Patel, A, Slesarev, A, Mondragon, A. | | Deposit date: | 2005-05-21 | | Release date: | 2006-01-31 | | Last modified: | 2023-12-06 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | Structure of the N-terminal fragment of topoisomerase V reveals a new family of topoisomerases
Embo J., 25, 2006
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1QO4
 | | ARABIDOPSIS THALIANA PEROXIDASE A2 AT ROOM TEMPERATURE | | Descriptor: | CALCIUM ION, PEROXIDASE, PROTOPORPHYRIN IX CONTAINING FE | | Authors: | Henriksen, A, Gajhede, M. | | Deposit date: | 1999-11-02 | | Release date: | 2000-11-02 | | Last modified: | 2023-12-13 | | Method: | X-RAY DIFFRACTION (3 Å) | | Cite: | Differential Activity and Structure of Highly Similar Peroxidases. Spectroscopic, Crystallographic, and Enzymatic Analyses of Lignifying Arabidopsis Thaliana Peroxidase A2 and Horseradish Peroxidase A2
Biochemistry, 40, 2001
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3DB3
 | | Crystal structure of the tandem tudor domains of the E3 ubiquitin-protein ligase UHRF1 in complex with trimethylated histone H3-K9 peptide | | Descriptor: | E3 ubiquitin-protein ligase UHRF1, Trimethylated histone H3-K9 peptide | | Authors: | Walker, J.R, Avvakumov, G.V, Xue, S, Dong, A, Li, Y, Bountra, C, Weigelt, J, Arrowsmith, C.H, Edwards, A.M, Bochkarev, A, Dhe-Paganon, S, Structural Genomics Consortium (SGC) | | Deposit date: | 2008-05-30 | | Release date: | 2008-09-16 | | Last modified: | 2012-04-18 | | Method: | X-RAY DIFFRACTION (2.4 Å) | | Cite: | Recognition of multivalent histone states associated with heterochromatin by UHRF1 protein.
J.Biol.Chem., 286, 2011
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1E3F
 | | Structure of human transthyretin complexed with bromophenols: a new mode of binding | | Descriptor: | TRANSTHYRETIN | | Authors: | Ghosh, M, Meerts, I.A.T.M, Cook, A, Bergman, A, Brouwer, A, Johnson, L.N. | | Deposit date: | 2000-06-14 | | Release date: | 2000-08-29 | | Last modified: | 2023-12-13 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | Structure of Human Transthyretin Complexed with Bromophenols : A New Mode of Binding
Acta Crystallogr.,Sect.D, 56, 2000
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2LGJ
 | | Solution structure of MsPTH | | Descriptor: | Peptidyl-tRNA hydrolase | | Authors: | Yadav, R, Pathak, P, Pulavarti, S, Jain, A, Kumar, A, Shukla, V, Arora, A. | | Deposit date: | 2011-07-27 | | Release date: | 2012-08-01 | | Last modified: | 2024-05-01 | | Method: | SOLUTION NMR | | Cite: | Solution structure and backbone dynamics of Peptidyl t-RNA hydrolase from Mycobacterium smegmatis
To be Published
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4CFN
 | | Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors. | | Descriptor: | 2,3-DIHYDROXY-1,4-DITHIOBUTANE, 6-(cyclohexylmethoxy)-8-(trifluoromethyl)-9H-purin-2-amine, CYCLIN-A2, ... | | Authors: | Carbain, B, Paterson, D.J, Anscombe, E, Campbell, A, Cano, C, Echalier, A, Endicott, J, Golding, B.T, Haggerty, K, Hardcastle, I.R, Jewsbury, P, Newell, D.R, Noble, M.E.M, Roche, C, Wang, L.Z, Griffin, R. | | Deposit date: | 2013-11-19 | | Release date: | 2013-12-18 | | Last modified: | 2023-12-20 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | 8-Substituted O6-Cyclohexylmethylguanine Cdk2 Inhibitors; Using Structure-Based Inhibitor Design to Optimise an Alternative Binding Mode.
J.Med.Chem., 57, 2014
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2GUH
 | | Crystal Structure of the Putative TetR-family Transcriptional Regulator from Rhodococcus sp. RHA1 | | Descriptor: | 1,2-ETHANEDIOL, MAGNESIUM ION, Putative TetR-family transcriptional regulator | | Authors: | Kim, Y, Joachimiak, A, Skarina, T, Zheng, H, Edwards, A, Savchenko, A, Midwest Center for Structural Genomics (MCSG) | | Deposit date: | 2006-04-30 | | Release date: | 2006-05-30 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (1.52 Å) | | Cite: | Crystal Structure of the Putative TetR-family Transcriptional Regulator from Rhodococcus sp. RHA1
To be Published
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2GNQ
 | | Structure of wdr5 | | Descriptor: | CHLORIDE ION, WD-repeat protein 5 | | Authors: | Min, J, Schuetz, A, Allali-Hassani, A, Loppnau, P, Vedadi, M, Weigelt, J, Sundstrom, M, Edwards, A.M, Arrowsmith, C.H, Bochkarev, A, Plotnikov, A.N, Structural Genomics Consortium (SGC) | | Deposit date: | 2006-04-10 | | Release date: | 2006-06-06 | | Last modified: | 2023-08-30 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | Structural basis for molecular recognition and presentation of histone H3 By WDR5.
Embo J., 25, 2006
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2H0U
 | | Crystal structure of NAD(P)H-flavin oxidoreductase from Helicobacter pylori | | Descriptor: | FLAVIN MONONUCLEOTIDE, NADPH-flavin oxidoreductase | | Authors: | Chang, C, Xu, X, Zheng, H, Savchenko, A, Edwards, A, Joachimiak, A, Midwest Center for Structural Genomics (MCSG) | | Deposit date: | 2006-05-15 | | Release date: | 2006-06-13 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | Crystal structure of NAD(P)H-flavin oxidoreductase from Helicobacter pylori
To be Published
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2H9N
 | | WDR5 in complex with monomethylated H3K4 peptide | | Descriptor: | H3 histone, WD-repeat protein 5 | | Authors: | Min, J.R, Schuetz, A, Allali-Hassani, A, Martin, F, Loppnau, P, Vedadi, M, Weigelt, J, Sundstrom, M, Edwards, A.M, Arrowsmith, C.H, Bochkarev, A, Plotnikov, A.N, Structural Genomics Consortium (SGC) | | Deposit date: | 2006-06-10 | | Release date: | 2006-08-01 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Structural basis for molecular recognition and presentation of histone H3 By WDR5.
Embo J., 25, 2006
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2H9M
 | | WDR5 in complex with unmodified H3K4 peptide | | Descriptor: | H3 histone, WD-repeat protein 5 | | Authors: | Min, J.R, Schuetz, A, Allali-Hassani, A, Martin, F, Loppnau, P, Vedadi, M, Weigelt, J, Sundstrom, M, Edwards, A.M, Arrowsmith, C.H, Bochkarev, A, Plotnikov, A.N, Structural Genomics Consortium (SGC) | | Deposit date: | 2006-06-10 | | Release date: | 2006-08-01 | | Last modified: | 2024-02-14 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | Structural basis for molecular recognition and presentation of histone H3 By WDR5.
Embo J., 25, 2006
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4HYS
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2HEO
 | | General Structure-Based Approach to the Design of Protein Ligands: Application to the Design of Kv1.2 Potassium Channel Blockers. | | Descriptor: | 5'-D(*TP*CP*GP*CP*GP*CP*G)-3', Z-DNA binding protein 1 | | Authors: | Magis, C, Gasparini, S, Charbonnier, J.B, Stura, E, Le Du, M.H, Menez, A, Cuniasse, P. | | Deposit date: | 2006-06-21 | | Release date: | 2006-11-21 | | Last modified: | 2023-08-30 | | Method: | X-RAY DIFFRACTION (1.7 Å) | | Cite: | Structure-based secondary structure-independent approach to design protein ligands: Application to the design of Kv1.2 potassium channel blockers.
J.Am.Chem.Soc., 128, 2006
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2H8O
 | | The 1.6A crystal structure of the geranyltransferase from Agrobacterium tumefaciens | | Descriptor: | Geranyltranstransferase | | Authors: | Zhang, R, Xu, X, Gu, J, Savchenko, A, Edwards, A, Joachimiak, A, Midwest Center for Structural Genomics (MCSG) | | Deposit date: | 2006-06-07 | | Release date: | 2006-07-04 | | Last modified: | 2024-02-14 | | Method: | X-RAY DIFFRACTION (1.6 Å) | | Cite: | The 1.6A crystal structure of the geranyltransferase from Agrobacterium tumefaciens
To be Published
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