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7CK1
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BU of 7ck1 by Molmil
Crystal structure of arabidopsis CESA3 catalytic domain
Descriptor: Cellulose synthase A catalytic subunit 3 [UDP-forming],Cellulose synthase A catalytic subunit 3 [UDP-forming], MANGANESE (II) ION
Authors:Qiao, Z, Gao, Y.G.
Deposit date:2020-07-15
Release date:2021-03-17
Last modified:2021-03-31
Method:X-RAY DIFFRACTION (2.35 Å)
Cite:Structure of Arabidopsis CESA3 catalytic domain with its substrate UDP-glucose provides insight into the mechanism of cellulose synthesis.
Proc.Natl.Acad.Sci.USA, 118, 2021
7CK3
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BU of 7ck3 by Molmil
Crystal structure of Arabidopsis CESA3 catalytic domain
Descriptor: Cellulose synthase A catalytic subunit 3 [UDP-forming],Cellulose synthase A catalytic subunit 3 [UDP-forming]
Authors:Qiao, Z, Gao, Y.G.
Deposit date:2020-07-15
Release date:2021-03-17
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Structure of Arabidopsis CESA3 catalytic domain with its substrate UDP-glucose provides insight into the mechanism of cellulose synthesis.
Proc.Natl.Acad.Sci.USA, 118, 2021
7CK2
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BU of 7ck2 by Molmil
Crystal structure of Arabidopsis CESA3 catalytic domain with UDP-Glucose
Descriptor: Cellulose synthase A catalytic subunit 3 [UDP-forming],Cellulose synthase A catalytic subunit 3 [UDP-forming], MANGANESE (II) ION, URIDINE-5'-DIPHOSPHATE-GLUCOSE
Authors:Qiao, Z, Gao, Y.G.
Deposit date:2020-07-15
Release date:2021-03-17
Last modified:2021-03-31
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:Structure of Arabidopsis CESA3 catalytic domain with its substrate UDP-glucose provides insight into the mechanism of cellulose synthesis.
Proc.Natl.Acad.Sci.USA, 118, 2021
4PPB
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BU of 4ppb by Molmil
ITK kinase domain with compound 28 (N-{1-[(1S)-3-(DIMETHYLAMINO)-1-PHENYLPROPYL]-1H-PYRAZOL-4-YL}-6-(1H-PYRAZOL-4-YL)-1H-INDAZOLE-3-CARBOXAMIDE)
Descriptor: N-{1-[(1S)-3-(dimethylamino)-1-phenylpropyl]-1H-pyrazol-4-yl}-6-(1H-pyrazol-4-yl)-1H-indazole-3-carboxamide, Tyrosine-protein kinase ITK/TSK
Authors:Eigenbrot, C, Shia, S.
Deposit date:2014-02-26
Release date:2014-06-04
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.82 Å)
Cite:Discovery and optimization of indazoles as potent and selective interleukin-2 inducible T cell kinase (ITK) inhibitors.
Bioorg.Med.Chem.Lett., 24, 2014
4PPA
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BU of 4ppa by Molmil
ITK kinase domain with compound 11 (N-[1-(3-CYANOBENZYL)-1H-PYRAZOL-4-YL]-6-(1H-PYRAZOL-4-YL)-1H-INDAZOLE-3-CARBOXAMIDE)
Descriptor: N-[1-(3-cyanobenzyl)-1H-pyrazol-4-yl]-6-(1H-pyrazol-4-yl)-1H-indazole-3-carboxamide, Tyrosine-protein kinase ITK/TSK
Authors:Eigenbrot, C, Shia, S.
Deposit date:2014-02-26
Release date:2014-06-04
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.67 Å)
Cite:Discovery and optimization of indazoles as potent and selective interleukin-2 inducible T cell kinase (ITK) inhibitors.
Bioorg.Med.Chem.Lett., 24, 2014
2RDO
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BU of 2rdo by Molmil
50S subunit with EF-G(GDPNP) and RRF bound
Descriptor: 23S RIBOSOMAL RNA, 50S ribosomal protein L1, 50S ribosomal protein L11, ...
Authors:Gao, N, Zavialov, A.V, Ehrenberg, M, Frank, J.
Deposit date:2007-09-24
Release date:2008-03-04
Last modified:2024-02-21
Method:ELECTRON MICROSCOPY (9.1 Å)
Cite:Specific interaction between EF-G and RRF and its implication for GTP-dependent ribosome splitting into subunits.
J.Mol.Biol., 374, 2007
4PPC
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BU of 4ppc by Molmil
ITK kinase domain with compound 27 (N-{1-[(1R)-3-(DIMETHYLAMINO)-1-PHENYLPROPYL]-1H-PYRAZOL-4-YL}-6-(1H-PYRAZOL-4-YL)-1H-INDAZOLE-3-CARBOXAMIDE)
Descriptor: N-{1-[(1R)-3-(dimethylamino)-1-phenylpropyl]-1H-pyrazol-4-yl}-6-(1H-pyrazol-4-yl)-1H-indazole-3-carboxamide, Tyrosine-protein kinase ITK/TSK
Authors:Eigenbrot, C, Shia, S.
Deposit date:2014-02-26
Release date:2014-06-04
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.95 Å)
Cite:Discovery and optimization of indazoles as potent and selective interleukin-2 inducible T cell kinase (ITK) inhibitors.
Bioorg.Med.Chem.Lett., 24, 2014
4BQH
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BU of 4bqh by Molmil
Crystal structure of the uridine diphosphate N-acetylglucosamine pyrophosphorylase from Trypanosoma brucei in complex with inhibitor
Descriptor: (3S)-3-[2-(1,3-benzodioxol-5-yl)-2-oxidanylidene-ethyl]-4-bromanyl-5-methyl-3-oxidanyl-1H-indol-2-one, SULFATE ION, UDP-N-ACETYLGLUCOSAMINE PYROPHOSPHORYLASE
Authors:Fang, W, Raimi, O.G, vanAalten, D.M.F.
Deposit date:2013-05-30
Release date:2013-07-17
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:A Novel Allosteric Inhibitor of the Uridine Diphosphate N-Acetylglucosamine Pyrophosphorylase from Trypanosoma Brucei.
Acs Chem.Biol., 8, 2013
3S28
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BU of 3s28 by Molmil
The crystal structure of sucrose synthase-1 in complex with a breakdown product of the UDP-glucose
Descriptor: 1,5-anhydro-D-arabino-hex-1-enitol, 1,5-anhydro-D-fructose, MALONIC ACID, ...
Authors:Zheng, Y, Garavito, R.M.
Deposit date:2011-05-16
Release date:2011-08-24
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:The Structure of Sucrose Synthase-1 from Arabidopsis thaliana and Its Functional Implications.
J.Biol.Chem., 286, 2011
3S27
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BU of 3s27 by Molmil
The crystal structure of sucrose synthase-1 from Arabidopsis thaliana and its functional implications.
Descriptor: MALONIC ACID, POTASSIUM ION, SULFATE ION, ...
Authors:Zheng, Y, Garavito, R.M.
Deposit date:2011-05-16
Release date:2011-08-24
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (2.91 Å)
Cite:The Structure of Sucrose Synthase-1 from Arabidopsis thaliana and Its Functional Implications.
J.Biol.Chem., 286, 2011
6S2I
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BU of 6s2i by Molmil
Anti-tumor antibody 14F7-derived scFv in complex with NeuGc Gm3
Descriptor: N-glycolyl-alpha-neuraminic acid-(2-3)-beta-D-galactopyranose-(1-4)-beta-D-glucopyranose, scFv C1
Authors:Bjerregaard-Andersen, K, Heggelund, J.E, Krengel, U.
Deposit date:2019-06-20
Release date:2020-07-15
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (2.285 Å)
Cite:Key role of a structural water molecule for the specificity of 14F7-An antitumor antibody targeting the NeuGc GM3 ganglioside.
Glycobiology, 31, 2021
3CQU
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BU of 3cqu by Molmil
Crystal Structure of Akt-1 complexed with substrate peptide and inhibitor
Descriptor: Glycogen synthase kinase-3 beta, N-[2-(5-methyl-4H-1,2,4-triazol-3-yl)phenyl]-7H-pyrrolo[2,3-d]pyrimidin-4-amine, RAC-alpha serine/threonine-protein kinase
Authors:Pandit, J.
Deposit date:2008-04-03
Release date:2008-05-27
Last modified:2021-10-20
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Synthesis and structure based optimization of novel Akt inhibitors
Bioorg.Med.Chem.Lett., 18, 2008
6SID
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BU of 6sid by Molmil
Crystal structure of the C-lobe of drosophila Arc 1 at atomic resolution
Descriptor: Activity-regulated cytoskeleton associated protein 1
Authors:Hallin, E.I, Kursula, P.
Deposit date:2019-08-09
Release date:2019-08-28
Last modified:2024-06-19
Method:X-RAY DIFFRACTION (1.05 Å)
Cite:Crystal and solution structures reveal oligomerization of individual capsid homology domains of Drosophila Arc.
Plos One, 16, 2021
6SIB
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BU of 6sib by Molmil
Crystal structure of the domain-swapped N-lobe dimer of drosophila Arc 2
Descriptor: Activity-regulated cytoskeleton associated protein 2
Authors:Hallin, E.I, Kursula, P.
Deposit date:2019-08-09
Release date:2019-08-28
Last modified:2024-06-19
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Crystal and solution structures reveal oligomerization of individual capsid homology domains of Drosophila Arc.
Plos One, 16, 2021
6SVH
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BU of 6svh by Molmil
Protein allostery of the WW domain at atomic resolution: FFpSPR bound structure
Descriptor: Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1
Authors:Strotz, D, Orts, J, Friedmann, M, Guntert, P, Vogeli, B, Riek, R.
Deposit date:2019-09-18
Release date:2020-09-30
Last modified:2024-06-19
Method:SOLUTION NMR
Cite:Protein Allostery at Atomic Resolution.
Angew.Chem.Int.Ed.Engl., 59, 2020
6SVE
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BU of 6sve by Molmil
Protein allostery of the WW domain at atomic resolution: pCdc25C bound structure
Descriptor: Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1
Authors:Strotz, D, Orts, J, Friedmann, M, Guntert, P, Vogeli, B, Riek, R.
Deposit date:2019-09-18
Release date:2020-10-07
Last modified:2024-06-19
Method:SOLUTION NMR
Cite:Protein Allostery at Atomic Resolution.
Angew.Chem.Int.Ed.Engl., 59, 2020
6SVC
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BU of 6svc by Molmil
Protein allostery of the WW domain at atomic resolution: apo structure
Descriptor: Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1
Authors:Strotz, D, Orts, J, Friedmann, M, Guntert, P, Vogeli, B, Riek, R.
Deposit date:2019-09-18
Release date:2020-09-30
Last modified:2024-06-19
Method:SOLUTION NMR
Cite:Protein Allostery at Atomic Resolution.
Angew.Chem.Int.Ed.Engl., 59, 2020
3CQW
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BU of 3cqw by Molmil
Crystal Structure of Akt-1 complexed with substrate peptide and inhibitor
Descriptor: 5-(5-chloro-7H-pyrrolo[2,3-d]pyrimidin-4-yl)-4,5,6,7-tetrahydro-1H-imidazo[4,5-c]pyridine, Glycogen synthase kinase-3 beta, MANGANESE (II) ION, ...
Authors:Pandit, J.
Deposit date:2008-04-03
Release date:2008-05-27
Last modified:2021-10-20
Method:X-RAY DIFFRACTION (2 Å)
Cite:Synthesis and structure based optimization of novel Akt inhibitors
Bioorg.Med.Chem.Lett., 18, 2008
6SIE
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BU of 6sie by Molmil
Crystal structure of the C-lobe of drosophila Arc 2
Descriptor: Activity-regulated cytoskeleton associated protein 2, SULFATE ION
Authors:Hallin, E.I, Kursula, P.
Deposit date:2019-08-09
Release date:2019-08-28
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Crystal and solution structures reveal oligomerization of individual capsid homology domains of Drosophila Arc.
Plos One, 16, 2021
3BYZ
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BU of 3byz by Molmil
2-Amino-1,3-thiazol-4(5H)-ones as Potent and Selective 11-Hydroxysteroid Dehydrogenase Type 1 Inhibitors
Descriptor: (5S)-2-(cyclooctylamino)-5-methyl-5-propyl-1,3-thiazol-4(5H)-one, Corticosteroid 11-beta-dehydrogenase isozyme 1, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
Authors:Zhang, J, Jordan, S.R, Li, V.
Deposit date:2008-01-16
Release date:2008-02-12
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.69 Å)
Cite:2-amino-1,3-thiazol-4(5H)-ones as potent and selective 11beta-hydroxysteroid dehydrogenase type 1 inhibitors: enzyme-ligand co-crystal structure and demonstration of pharmacodynamic effects in C57Bl/6 mice.
J.Med.Chem., 51, 2008
1ZTX
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BU of 1ztx by Molmil
West Nile Virus Envelope Protein DIII in complex with neutralizing E16 antibody Fab
Descriptor: Envelope protein, Heavy Chain of E16 Antibody, Light Chain of E16 Antibody
Authors:Nybakken, G.E, Oliphant, T, Diamond, M.S, Fremont, D.H.
Deposit date:2005-05-27
Release date:2005-10-04
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structural basis of West Nile virus neutralization by a therapeutic antibody.
Nature, 437, 2005
3VPB
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BU of 3vpb by Molmil
ArgX from Sulfolobus tokodaii complexed with LysW/Glu/ADP/Mg/Zn/Sulfate
Descriptor: ADENOSINE-5'-DIPHOSPHATE, Alpha-aminoadipate carrier protein lysW, GLUTAMIC ACID, ...
Authors:Tomita, T, Ouchi, T, Kuzuyama, T, Nishiyama, M.
Deposit date:2012-02-29
Release date:2013-02-27
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Lysine and arginine biosyntheses mediated by a common carrier protein in Sulfolobus
Nat.Chem.Biol., 9, 2013
3VPD
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BU of 3vpd by Molmil
LysX from Thermus thermophilus complexed with AMP-PNP
Descriptor: CITRIC ACID, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, Ribosomal protein S6 modification protein, ...
Authors:Tomita, T, Ouchi, T, Kuzuyama, T, Nishiyama, M.
Deposit date:2012-02-29
Release date:2013-02-27
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Lysine and arginine biosyntheses mediated by a common carrier protein in Sulfolobus.
Nat.Chem.Biol., 9, 2013
1UOH
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BU of 1uoh by Molmil
HUMAN GANKYRIN
Descriptor: 26S PROTEASOME NON-ATPASE REGULATORY SUBUNIT 10
Authors:Krzywda, S, Brzozowski, A.M, Wilkinson, A.J.
Deposit date:2003-09-17
Release date:2003-10-30
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:The Crystal Structure of Gankyrin, an Oncoprotein Found in Complexes with Cyclin-Dependent Kinase 4, a 19 S Proteasomal ATPase Regulator, and the Tumor Suppressors Rb and P53
J.Biol.Chem., 279, 2004
3VPC
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BU of 3vpc by Molmil
ArgX from Sulfolobus tokodaii complexed with ADP
Descriptor: ADENOSINE-5'-DIPHOSPHATE, Putative acetylornithine deacetylase
Authors:Tomita, T, Horie, A, Kuzuyama, T, Nishiyama, M.
Deposit date:2012-02-29
Release date:2013-02-27
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (1.87 Å)
Cite:Lysine and arginine biosyntheses mediated by a common carrier protein in Sulfolobus.
Nat.Chem.Biol., 9, 2013

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数据于2024-08-28公开中

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