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6RCN
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BU of 6rcn by Molmil
Crystal structure of REXO2-D199A-dAdA
Descriptor: DNA (5'-D(P*AP*A)-3'), MAGNESIUM ION, Oligoribonuclease, ...
Authors:Spahr, H, Nicholls, T.J, Larsson, N.G, Gustafsson, C.M.
Deposit date:2019-04-11
Release date:2019-10-09
Last modified:2024-05-15
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:Dinucleotide Degradation by REXO2 Maintains Promoter Specificity in Mammalian Mitochondria.
Mol.Cell, 76, 2019
8GU0
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BU of 8gu0 by Molmil
Crystal structure of a fungal halogenase RadH
Descriptor: CHLORIDE ION, FLAVIN-ADENINE DINUCLEOTIDE, Non-heme halogenase radH, ...
Authors:Jiang, S.M, Brown, C.J.
Deposit date:2022-09-09
Release date:2023-07-26
Last modified:2024-05-29
Method:X-RAY DIFFRACTION (2.42 Å)
Cite:Further Characterization of Fungal Halogenase RadH and Its Homologs.
Biomolecules, 13, 2023
6LB9
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BU of 6lb9 by Molmil
Magnesium ion-bound SspB crystal structure
Descriptor: DUF4007 domain-containing protein, MAGNESIUM ION
Authors:Liqiong, L, Yubing, Z.
Deposit date:2019-11-13
Release date:2020-03-25
Last modified:2024-03-27
Method:X-RAY DIFFRACTION (2.227 Å)
Cite:SspABCD-SspE is a phosphorothioation-sensing bacterial defence system with broad anti-phage activities.
Nat Microbiol, 5, 2020
2NAE
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BU of 2nae by Molmil
Membrane-bound mouse CD28 cytoplasmic tail
Descriptor: T-cell-specific surface glycoprotein CD28
Authors:Li, H, Xu, C, Pan, W.
Deposit date:2015-12-23
Release date:2016-12-21
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:Dynamic regulation of CD28 conformation and signaling by charged lipids and ions.
Nat.Struct.Mol.Biol., 24, 2017
1QR9
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BU of 1qr9 by Molmil
INHIBITION OF HIV-1 INFECTIVITY BY THE GP41 CORE: ROLE OF A CONSERVED HYDROPHOBIC CAVITY IN MEMBRANE FUSION
Descriptor: GP41 ENVELOPE PROTEIN
Authors:Ji, H, Shu, W, Burling, F.T, Jiang, S.B, Lu, M.
Deposit date:1999-06-18
Release date:1999-11-26
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Inhibition of human immunodeficiency virus type 1 infectivity by the gp41 core: role of a conserved hydrophobic cavity in membrane fusion.
J.Virol., 73, 1999
1QR8
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BU of 1qr8 by Molmil
INHIBITION OF HIV-1 INFECTIVITY BY THE GP41 CORE: ROLE OF A CONSERVED HYDROPHOBIC CAVITY IN MEMBRANE FUSION
Descriptor: GP41 ENVELOPE PROTEIN
Authors:Ji, H, Shu, W, Burling, F.T, Jiang, S.B, Lu, M.
Deposit date:1999-06-18
Release date:1999-11-26
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Inhibition of human immunodeficiency virus type 1 infectivity by the gp41 core: role of a conserved hydrophobic cavity in membrane fusion.
J.Virol., 73, 1999
5KLP
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BU of 5klp by Molmil
Crystal structure of HopZ1a in complex with IP6
Descriptor: CITRIC ACID, INOSITOL HEXAKISPHOSPHATE, Orf34
Authors:Zhang, Z.-M, Song, J.
Deposit date:2016-06-24
Release date:2016-08-10
Last modified:2020-10-14
Method:X-RAY DIFFRACTION (2.002 Å)
Cite:Structure of a pathogen effector reveals the enzymatic mechanism of a novel acetyltransferase family.
Nat.Struct.Mol.Biol., 23, 2016
6LXT
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BU of 6lxt by Molmil
Structure of post fusion core of 2019-nCoV S2 subunit
Descriptor: Spike protein S2, TETRAETHYLENE GLYCOL, ZINC ION
Authors:Zhu, Y, Sun, F.
Deposit date:2020-02-11
Release date:2020-02-26
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Inhibition of SARS-CoV-2 (previously 2019-nCoV) infection by a highly potent pan-coronavirus fusion inhibitor targeting its spike protein that harbors a high capacity to mediate membrane fusion.
Cell Res., 30, 2020
5HFM
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BU of 5hfm by Molmil
Gp41-targeting HIV-1 fusion inhibitors with hook-like Ile-Asp-Leu tail
Descriptor: Envelope glycoprotein gp160,gp41 CHR region, TRIS(HYDROXYETHYL)AMINOMETHANE
Authors:Zhu, Y, Ye, S, Zhang, R.
Deposit date:2016-01-07
Release date:2017-01-11
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (2.298 Å)
Cite:Rational improvement of gp41-targeting HIV-1 fusion inhibitors: an innovatively designed Ile-Asp-Leu tail with alternative conformations
Sci Rep, 6, 2016
5HFL
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BU of 5hfl by Molmil
Gp41-targeting HIV-1 fusion inhibitors with helical Ile-Asp-Leu tail
Descriptor: Envelope glycoprotein,gp41 CHR region
Authors:Zhu, Y, Ye, S, Zhang, R.
Deposit date:2016-01-07
Release date:2017-01-11
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (2.294 Å)
Cite:Rational improvement of gp41-targeting HIV-1 fusion inhibitors: an innovatively designed Ile-Asp-Leu tail with alternative conformations
Sci Rep, 6, 2016
5H0N
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BU of 5h0n by Molmil
Crystal structure of HIV-1 fusion inhibitor MT-WQ-IDL bound to gp41 NHR
Descriptor: HIV-1 fusion inhibitor MT-WQ-IDL, HIV-1 gp41 NHR
Authors:Zhu, Y, Ye, S, Zhang, R.
Deposit date:2016-10-06
Release date:2016-11-02
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Creating an Artificial Tail Anchor as a Novel Strategy To Enhance the Potency of Peptide-Based HIV Fusion Inhibitors
J. Virol., 91, 2017
6JIV
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BU of 6jiv by Molmil
SspE crystal structure
Descriptor: SspE protein
Authors:Bing, Y.Z, Yang, H.G.
Deposit date:2019-02-23
Release date:2020-03-25
Last modified:2020-07-08
Method:X-RAY DIFFRACTION (3.31 Å)
Cite:SspABCD-SspE is a phosphorothioation-sensing bacterial defence system with broad anti-phage activities.
Nat Microbiol, 5, 2020
6JUF
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BU of 6juf by Molmil
SspB crystal structure
Descriptor: SspB protein
Authors:Liqiong, L, Yubing, Z.
Deposit date:2019-04-13
Release date:2020-03-25
Last modified:2024-03-27
Method:X-RAY DIFFRACTION (1.587 Å)
Cite:SspABCD-SspE is a phosphorothioation-sensing bacterial defence system with broad anti-phage activities.
Nat Microbiol, 5, 2020
5W5J
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BU of 5w5j by Molmil
Identification of potent and selective RIPK2 inhibitors for the treatment of inflammatory diseases
Descriptor: N-(2-chlorophenyl)pyrazolo[1,5-a]pyridine-3-carboxamide, Receptor-interacting serine/threonine-protein kinase 2, SULFATE ION
Authors:Kreusch, A, Spraggon, G.
Deposit date:2017-06-15
Release date:2017-10-25
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (2.85 Å)
Cite:Identification of Potent and Selective RIPK2 Inhibitors for the Treatment of Inflammatory Diseases.
ACS Med Chem Lett, 8, 2017
2VSL
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BU of 2vsl by Molmil
Crystal Structure of XIAP BIR3 with a Bivalent Smac Mimetic
Descriptor: BACULOVIRAL IAP REPEAT-CONTAINING PROTEIN 4, PEPTIDE (MAA-LYS-PRO-PHE), POLYETHYLENE GLYCOL (N=34), ...
Authors:Meagher, J.L, Stuckey, J.A.
Deposit date:2008-04-24
Release date:2008-09-02
Last modified:2024-05-01
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Interaction of a Cyclic, Bivalent Smac Mimetic with the X-Linked Inhibitor of Apoptosis Protein.
Biochemistry, 47, 2008
5W5O
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BU of 5w5o by Molmil
Identification of potent and selective RIPK2 inhibitors for the treatment of inflammatory diseases.
Descriptor: 4-{6-(tert-butylsulfonyl)-7-[2-(4-methylpiperazin-1-yl)ethoxy]imidazo[1,2-a]pyridin-3-yl}-6-chloropyridin-2-amine, Receptor-interacting serine/threonine-protein kinase 2
Authors:Kreusch, A, Spraggon, G.
Deposit date:2017-06-15
Release date:2017-10-25
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (2.89 Å)
Cite:Identification of Potent and Selective RIPK2 Inhibitors for the Treatment of Inflammatory Diseases.
ACS Med Chem Lett, 8, 2017
5VAG
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BU of 5vag by Molmil
Crystal structure of H7-specific antibody m826 in complex with the HA1 domain of hemagglutinin from H7N9 influenza virus
Descriptor: 1,2-ETHANEDIOL, Heavy chain of antibody m826, Hemagglutinin, ...
Authors:Song, H, Ying, T, Ji, X.
Deposit date:2017-03-26
Release date:2017-12-20
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:A Potent Germline-like Human Monoclonal Antibody Targets a pH-Sensitive Epitope on H7N9 Influenza Hemagglutinin.
Cell Host Microbe, 22, 2017
5CMZ
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BU of 5cmz by Molmil
Artificial HIV fusion inhibitor AP3 fused to the C-terminus of gp41 NHR
Descriptor: 1,2-ETHANEDIOL, 1-ETHOXY-2-(2-ETHOXYETHOXY)ETHANE, Artificial HIV entry inhibitor AP3, ...
Authors:Zhu, Y, Ye, S, Zhang, R.
Deposit date:2015-07-17
Release date:2015-09-16
Method:X-RAY DIFFRACTION (2.574 Å)
Cite:Improved Pharmacological and Structural Properties of HIV Fusion Inhibitor AP3 over Enfuvirtide: Highlighting Advantages of Artificial Peptide Strategy.
Sci Rep, 5, 2015
5CN0
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BU of 5cn0 by Molmil
Artificial HIV fusion inhibitor AP2 fused to the C-terminus of gp41 NHR
Descriptor: DI(HYDROXYETHYL)ETHER, Envelope glycoprotein,AP2, MAGNESIUM ION
Authors:Zhu, Y, Ye, S, Zhang, R.
Deposit date:2015-07-17
Release date:2015-09-16
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (1.901 Å)
Cite:Improved Pharmacological and Structural Properties of HIV Fusion Inhibitor AP3 over Enfuvirtide: Highlighting Advantages of Artificial Peptide Strategy.
Sci Rep, 5, 2015
5CMU
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BU of 5cmu by Molmil
Artificial HIV fusion inhibitor AP1 fused to the C-terminus of gp41 NHR
Descriptor: Envelope glycoprotein,AP1, GLYCEROL
Authors:Zhu, Y, Ye, S, Zhang, R.
Deposit date:2015-07-17
Release date:2015-09-16
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (2.113 Å)
Cite:Improved Pharmacological and Structural Properties of HIV Fusion Inhibitor AP3 over Enfuvirtide: Highlighting Advantages of Artificial Peptide Strategy.
Sci Rep, 5, 2015
6A0A
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BU of 6a0a by Molmil
Structure of a triple-helix region of human collagen type III
Descriptor: collagen type III peptide
Authors:Yang, X, Zhu, Y, Ye, S, Zhang, R.
Deposit date:2018-06-05
Release date:2018-12-26
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (1.502 Å)
Cite:Characterization by high-resolution crystal structure analysis of a triple-helix region of human collagen type III with potent cell adhesion activity.
Biochem. Biophys. Res. Commun., 508, 2019
6L6H
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BU of 6l6h by Molmil
Crystal structure of Lpg0189
Descriptor: ACETATE ION, GLYCEROL, Uncharacterized protein Lpg0189
Authors:Ge, H, Chen, X.
Deposit date:2019-10-29
Release date:2019-11-27
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.403 Å)
Cite:Crystal structure of a hypothetical T2SS effector Lpg0189 from Legionella pneumophila reveals a novel protein fold.
Biochem.Biophys.Res.Commun., 521, 2020
6L6G
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BU of 6l6g by Molmil
Crystal structure of SeMet_Lpg0189
Descriptor: GLYCEROL, Uncharacterized protein Lpg0189
Authors:Ge, H, Chen, X.
Deposit date:2019-10-29
Release date:2019-11-27
Last modified:2020-01-15
Method:X-RAY DIFFRACTION (1.98 Å)
Cite:Crystal structure of a hypothetical T2SS effector Lpg0189 from Legionella pneumophila reveals a novel protein fold.
Biochem.Biophys.Res.Commun., 521, 2020
6A0C
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BU of 6a0c by Molmil
Structure of a triple-helix region of human collagen type III
Descriptor: 1,2-ETHANEDIOL, GLYCEROL, collagen type III peptide
Authors:Yang, X, Zhu, Y, Ye, S, Zhang, R.
Deposit date:2018-06-05
Release date:2018-12-26
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (1.501 Å)
Cite:Characterization by high-resolution crystal structure analysis of a triple-helix region of human collagen type III with potent cell adhesion activity.
Biochem. Biophys. Res. Commun., 508, 2019
6M4J
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BU of 6m4j by Molmil
SspA in complex with cysteine
Descriptor: CYSTEINE, PYRIDOXAL-5'-PHOSPHATE, SspA complex protein
Authors:Liu, L, Gao, H.
Deposit date:2020-03-07
Release date:2020-04-22
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structural Analysis of an l-Cysteine Desulfurase from an Ssp DNA Phosphorothioation System.
Mbio, 11, 2020

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数据于2024-07-10公开中

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