3AU5
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3WA0
| Crystal structure of merlin complexed with DCAF1/VprBP | Descriptor: | Merlin, Protein VPRBP | Authors: | Mori, T, Gotoh, S, Shirakawa, M, Hakoshima, T. | Deposit date: | 2013-04-20 | Release date: | 2014-05-28 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.31 Å) | Cite: | Structural basis of DDB1-and-Cullin 4-associated Factor 1 (DCAF1) recognition by merlin/NF2 and its implication in tumorigenesis by CD44-mediated inhibition of merlin suppression of DCAF1 function. Genes Cells, 19, 2014
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2ZPY
| Crystal structure of the mouse radxin FERM domain complexed with the mouse CD44 cytoplasmic peptide | Descriptor: | CD44 antigen, Radixin | Authors: | Mori, T, Kitano, K, Terawaki, S, Maesaki, R, Fukami, Y, Hakoshima, T. | Deposit date: | 2008-07-31 | Release date: | 2008-08-26 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Structural basis for CD44 recognition by ERM proteins J.Biol.Chem., 283, 2008
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3AU4
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3X23
| Radixin complex | Descriptor: | Peptide from Matrix metalloproteinase-14, Radixin | Authors: | Terawaki, S, Kitano, K, Aoyama, M, Mori, T, Hakoshima, T. | Deposit date: | 2014-12-09 | Release date: | 2015-10-21 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.396 Å) | Cite: | MT1-MMP recognition by ERM proteins and its implication in CD44 shedding Genes Cells, 20, 2015
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2E4H
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2E3I
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2E3H
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2ZSH
| Structural basis of gibberellin(GA3)-induced DELLA recognition by the gibberellin receptor | Descriptor: | DELLA protein GAI, GIBBERELLIN A3, Probable gibberellin receptor GID1L1 | Authors: | Murase, K, Hirano, Y, Sun, T.P, Hakoshima, T. | Deposit date: | 2008-09-10 | Release date: | 2008-11-25 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Gibberellin-induced DELLA recognition by the gibberellin receptor GID1 Nature, 456, 2008
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3AAF
| Structure of WRN RQC domain bound to double-stranded DNA | Descriptor: | ACETATE ION, DNA (5'-D(*AP*CP*CP*CP*TP*AP*AP*TP*TP*AP*GP*GP*GP*T)-3'), Werner syndrome ATP-dependent helicase | Authors: | Kitano, K, Hakoshima, T. | Deposit date: | 2009-11-16 | Release date: | 2010-02-16 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Structural basis for DNA strand separation by the unconventional winged-helix domain of RecQ helicase WRN Structure, 18, 2010
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336D
| INTERACTION BETWEEN LEFT-HANDED Z-DNA AND POLYAMINE-3 THE CRYSTAL STRUCTURE OF THE D(CG)3 AND THERMOSPERMINE COMPLEX | Descriptor: | DNA (5'-D(*CP*GP*CP*GP*CP*G)-3'), MAGNESIUM ION, N-(3-AMINO-PROPYL)-N-(5-AMINOPROPYL)-1,4-DIAMINOBUTANE | Authors: | Ohishi, H, Terasoma, N, Nakanishi, I, Van Der Marel, G, Van Boom, J.H, Rich, A, Wang, A.H.-J, Hakoshima, T, Tomita, K.-I. | Deposit date: | 1997-06-24 | Release date: | 1998-04-10 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (1 Å) | Cite: | Interaction between left-handed Z-DNA and polyamine - 3. The crystal structure of the d(CG)3 and thermospermine complex. FEBS Lett., 398, 1996
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2ZSI
| Structural basis of gibberellin(GA4)-induced DELLA recognition by the gibberellin receptor | Descriptor: | DELLA protein GAI, GIBBERELLIN A4, Probable gibberellin receptor GID1L1 | Authors: | Murase, K, Hirano, Y, Sun, T.P, Hakoshima, T. | Deposit date: | 2008-09-10 | Release date: | 2008-11-25 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Gibberellin-induced DELLA recognition by the gibberellin receptor GID1 Nature, 456, 2008
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3AH8
| Structure of heterotrimeric G protein Galpha-q beta gamma in complex with an inhibitor YM-254890 | Descriptor: | GUANOSINE-5'-DIPHOSPHATE, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... | Authors: | Nishimura, A, Kitano, K, Takasaki, J, Taniguchi, M, Mizuno, N, Tago, K, Hakoshima, T, Itoh, H. | Deposit date: | 2010-04-20 | Release date: | 2010-07-21 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | Structural basis for the specific inhibition of heterotrimeric Gq protein by a small molecule. Proc.Natl.Acad.Sci.USA, 107, 2010
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2D2Q
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2DPX
| Crystal Structure of human Rad GTPase | Descriptor: | GTP-binding protein RAD, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION | Authors: | Yanuar, A, Sakurai, S, Kitano, K, Hakoshima, T. | Deposit date: | 2006-05-18 | Release date: | 2006-08-08 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Crystal structure of human Rad GTPase of the RGK-family Genes Cells, 11, 2006
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2E1F
| Crystal structure of the HRDC Domain of Human Werner Syndrome Protein, WRN | Descriptor: | CHLORIDE ION, Werner syndrome ATP-dependent helicase | Authors: | Kitano, K, Yoshihara, N, Hakoshima, T. | Deposit date: | 2006-10-25 | Release date: | 2006-12-12 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Crystal structure of the HRDC domain of human Werner syndrome protein, WRN J.Biol.Chem., 282, 2007
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3W9R
| Crystal structure of the high-affinity abscisic acid receptor PYL9/RCAR9 bound to ABA | Descriptor: | (2Z,4E)-5-[(1S)-1-hydroxy-2,6,6-trimethyl-4-oxocyclohex-2-en-1-yl]-3-methylpenta-2,4-dienoic acid, Abscisic acid receptor PYL9, HEXAETHYLENE GLYCOL | Authors: | Nakagawa, M, Hirano, Y, Kagiyama, M, Shibata, N, Hakoshima, T. | Deposit date: | 2013-04-13 | Release date: | 2014-04-09 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Mechanism of high-affinity abscisic acid binding to PYL9/RCAR1. Genes Cells, 19, 2014
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3WE2
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3WE3
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2E1E
| Crystal structure of the HRDC Domain of Human Werner Syndrome Protein, WRN | Descriptor: | CHLORIDE ION, Werner syndrome ATP-dependent helicase | Authors: | Kitano, K, Yoshihara, N, Hakoshima, T. | Deposit date: | 2006-10-25 | Release date: | 2006-12-12 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Crystal structure of the HRDC domain of human Werner syndrome protein, WRN J.Biol.Chem., 282, 2007
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2F2U
| crystal structure of the Rho-kinase kinase domain | Descriptor: | 5-(1,4-DIAZEPAN-1-SULFONYL)ISOQUINOLINE, Rho-associated protein kinase 2 | Authors: | Yamaguchi, H, Hakoshima, T. | Deposit date: | 2005-11-18 | Release date: | 2006-04-25 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Molecular mechanism for the regulation of rho-kinase by dimerization and its inhibition by fasudil Structure, 14, 2006
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4TZC
| Crystal Structure of Murine Cereblon in Complex with Thalidomide | Descriptor: | Protein cereblon, S-Thalidomide, SULFATE ION, ... | Authors: | Chamberlain, P.P, Pagarigan, B, Delker, S, Leon, B. | Deposit date: | 2014-07-10 | Release date: | 2014-08-06 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (1.88 Å) | Cite: | Structural Basis for Responsiveness to Thalidomide-Analog Drugs Defined by the Crystal Structure of the Human Cereblon:DDB1:Lenalidomide Complex to be published
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4TZ4
| Crystal Structure of Human Cereblon in Complex with DDB1 and Lenalidomide | Descriptor: | DNA damage-binding protein 1, Protein cereblon, S-Lenalidomide, ... | Authors: | Chamberlain, P.P, Pagarigan, B, Delker, S, Leon, B, Riley, M. | Deposit date: | 2014-07-09 | Release date: | 2014-08-06 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (3.01 Å) | Cite: | Structural Basis for Responsiveness to Thalidomide-Analog Drugs Defined by the Crystal Structure of the Human Cereblon:DDB1:Lenalidomide Complex To Be Published
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4TZU
| Crystal Structure of Murine Cereblon in Complex with Pomalidomide | Descriptor: | Protein cereblon, S-Pomalidomide, SULFATE ION, ... | Authors: | Chamberlain, P.P, Pagarigan, B, Delker, S, Leon, B. | Deposit date: | 2014-07-10 | Release date: | 2014-08-06 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Structural Basis for Responsiveness to Thalidomide-Analog Drugs Defined by the Crystal Structure of the Human Cereblon:DDB1:Lenalidomide Complex to be published
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6LEO
| Crystal structure of thiosulfate transporter YeeE from Spirochaeta thermophila | Descriptor: | (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, Sulf_transp domain-containing protein, THIOSULFATE | Authors: | Tanaka, Y, Tsukazaki, T, Yoshikaie, K, Takeuchi, A, Uchino, S, Sugano, Y. | Deposit date: | 2019-11-26 | Release date: | 2020-09-02 | Last modified: | 2020-09-30 | Method: | X-RAY DIFFRACTION (2.52 Å) | Cite: | Crystal structure of a YeeE/YedE family protein engaged in thiosulfate uptake. Sci Adv, 6, 2020
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