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8TXJ
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BU of 8txj by Molmil
KRAS 1-169 G12C Mutant at 277k
Descriptor: GUANOSINE-5'-DIPHOSPHATE, Isoform 2B of GTPase KRas, MAGNESIUM ION
Authors:Deck, S.L, Xu, M, Milano, S.K, Aplin, C.
Deposit date:2023-08-23
Release date:2024-08-28
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:Temperature Gradient Structures of Oncogenic KRAS G12C Mutants
To Be Published
4R14
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BU of 4r14 by Molmil
Crystal structure of human CSN6 MPN domain
Descriptor: COP9 signalosome complex subunit 6, MERCURY (II) ION
Authors:Jiang, T, Xu, M, Ma, X.L.
Deposit date:2014-08-04
Release date:2014-10-22
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (2.601 Å)
Cite:Crystal structure of the human CSN6 MPN domain
Biochem.Biophys.Res.Commun., 453, 2014
2GL2
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BU of 2gl2 by Molmil
Crystal structure of the tetra mutant (T66G,R67G,F68G,Y69G) of bacterial adhesin FadA
Descriptor: adhesion A
Authors:Nithianantham, S, Xu, M, Wu, N, Shoham, M, Han, Y.W.
Deposit date:2006-04-04
Release date:2007-04-10
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Crystallization and preliminary X-ray data of the FadA adhesin from Fusobacterium nucleatum.
Acta Crystallogr.,Sect.F, 62, 2006
6ISL
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BU of 6isl by Molmil
SnoaL-like cyclase XimE with its product xiamenmycin B
Descriptor: (2R,3S)-2-methyl-2-(4-methylpent-3-enyl)-3-oxidanyl-3,4-dihydrochromene-6-carboxylic acid, XimE, SnoaL-like domain protein
Authors:He, B, Zhou, T, Bu, X, Weng, J, Xu, J, Lin, S, Zheng, J, Zhao, Y, Xu, M.
Deposit date:2018-11-16
Release date:2019-11-20
Last modified:2024-03-27
Method:X-RAY DIFFRACTION (1.77 Å)
Cite:Enzymatic Pyran Formation Involved in Xiamenmycin Biosynthesis
Acs Catalysis, 9, 2019
6ISK
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BU of 6isk by Molmil
SnoaL-like cyclase XimE
Descriptor: 1,2-ETHANEDIOL, MALONIC ACID, XimE, ...
Authors:He, B, Zhou, T, Bu, X, Weng, J, Xu, J, Lin, S, Zheng, J, Zhao, Y, Xu, M.
Deposit date:2018-11-16
Release date:2019-11-20
Last modified:2024-03-27
Method:X-RAY DIFFRACTION (1.77 Å)
Cite:Enzymatic Pyran Formation Involved in Xiamenmycin Biosynthesis
Acs Catalysis, 9, 2019
8JC0
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BU of 8jc0 by Molmil
V gamma9 V delta2 TCR and CD3 complex in LMNG
Descriptor: CHOLESTEROL, T cell receptor delta variable 2,T cell receptor delta constant, T cell receptor gamma variable 9,T cell receptor gamma constant 1, ...
Authors:Xin, W, Huang, B, Chi, X, Xu, M, Zhang, Y, Li, X, Su, Q, Zhou, Q.
Deposit date:2023-05-10
Release date:2024-05-08
Last modified:2024-06-19
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:Structures of human gamma delta T cell receptor-CD3 complex.
Nature, 630, 2024
5IY4
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BU of 5iy4 by Molmil
Crystal structure of human PCNA in complex with the PIP box of DVC1
Descriptor: DVC1 PIP box, Proliferating cell nuclear antigen
Authors:Jiang, T, Xu, M, Wang, Y.
Deposit date:2016-03-24
Release date:2016-06-08
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.945 Å)
Cite:Crystal structure of human PCNA in complex with the PIP box of DVC1
Biochem.Biophys.Res.Commun., 474, 2016
2B7T
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BU of 2b7t by Molmil
Structure of ADAR2 dsRBM1
Descriptor: Double-stranded RNA-specific editase 1
Authors:Stefl, R, Xu, M, Skrisovska, L, Emeson, R.B, Allain, F.H.-T.
Deposit date:2005-10-05
Release date:2006-03-14
Last modified:2024-05-22
Method:SOLUTION NMR
Cite:Structure and specific RNA binding of ADAR2 double-stranded RNA binding motifs.
Structure, 14, 2006
2B7V
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BU of 2b7v by Molmil
Structure of ADAR2 dsRBM2
Descriptor: Double-stranded RNA-specific editase 1
Authors:Stefl, R, Xu, M, Skrisovska, L, Emeson, R.B, Allain, F.H.-T.
Deposit date:2005-10-05
Release date:2006-03-14
Last modified:2024-05-22
Method:SOLUTION NMR
Cite:Structure and specific RNA binding of ADAR2 double-stranded RNA binding motifs.
Structure, 14, 2006
5Y61
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BU of 5y61 by Molmil
YfiB-YfiR complexed with GMP
Descriptor: GUANOSINE-5'-MONOPHOSPHATE, YfiB, YfiR
Authors:Zhou, L, Xu, M, Jiang, T.
Deposit date:2017-08-10
Release date:2017-09-20
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.99 Å)
Cite:Structural insights into the functional role of GMP in modulating the YfiBNR system
Biochem. Biophys. Res. Commun., 493, 2017
4GDF
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BU of 4gdf by Molmil
A Crystal Structure of SV40 Large T Antigen
Descriptor: DNA (32-MER), Large T antigen, ZINC ION
Authors:Chang, Y.P, Xu, M, Chen, X.S.
Deposit date:2012-07-31
Release date:2013-04-10
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Mechanism of Origin DNA Recognition and Assembly of an Initiator-Helicase Complex by SV40 Large Tumor Antigen.
Cell Rep, 3, 2013
8HOG
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BU of 8hog by Molmil
Crystal structure of Bcl-2 in complex with sonrotoclax
Descriptor: Apoptosis regulator Bcl-2, ~{N}-[4-[(4-methyl-4-oxidanyl-cyclohexyl)methylamino]-3-nitro-phenyl]sulfonyl-4-[2-[(2~{S})-2-(2-propan-2-ylphenyl)pyrrolidin-1-yl]-7-azaspiro[3.5]nonan-7-yl]-2-(1~{H}-pyrrolo[2,3-b]pyridin-5-yloxy)benzamide
Authors:Liu, J, Xu, M, Feng, Y, Hong, Y, Liu, Y.
Deposit date:2022-12-10
Release date:2024-01-17
Last modified:2024-05-15
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Sonrotoclax overcomes BCL2 G101V mutation-induced venetoclax resistance in preclinical models of hematologic malignancy.
Blood, 143, 2024
8HOH
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BU of 8hoh by Molmil
Crystal structure of Bcl-2 G101V in complex with sonrotoclax
Descriptor: Apoptosis regulator Bcl-2, ~{N}-[4-[(4-methyl-4-oxidanyl-cyclohexyl)methylamino]-3-nitro-phenyl]sulfonyl-4-[2-[(2~{S})-2-(2-propan-2-ylphenyl)pyrrolidin-1-yl]-7-azaspiro[3.5]nonan-7-yl]-2-(1~{H}-pyrrolo[2,3-b]pyridin-5-yloxy)benzamide
Authors:Liu, J, Xu, M, Feng, Y, Hong, Y, Liu, Y.
Deposit date:2022-12-10
Release date:2024-01-17
Last modified:2024-05-15
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Sonrotoclax overcomes BCL2 G101V mutation-induced venetoclax resistance in preclinical models of hematologic malignancy.
Blood, 143, 2024
8HOI
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BU of 8hoi by Molmil
Crystal structure of Bcl-2 D103Y in complex with sonrotoclax
Descriptor: Apoptosis regulator Bcl-2, FORMIC ACID, ~{N}-[4-[(4-methyl-4-oxidanyl-cyclohexyl)methylamino]-3-nitro-phenyl]sulfonyl-4-[2-[(2~{S})-2-(2-propan-2-ylphenyl)pyrrolidin-1-yl]-7-azaspiro[3.5]nonan-7-yl]-2-(1~{H}-pyrrolo[2,3-b]pyridin-5-yloxy)benzamide
Authors:Liu, J, Xu, M, Feng, Y, Hong, Y, Liu, Y.
Deposit date:2022-12-10
Release date:2024-01-17
Last modified:2024-05-15
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:Sonrotoclax overcomes BCL2 G101V mutation-induced venetoclax resistance in preclinical models of hematologic malignancy.
Blood, 143, 2024
4NOO
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BU of 4noo by Molmil
Molecular mechanism for self-protection against type VI secretion system in Vibrio cholerae
Descriptor: Putative uncharacterized protein, VgrG protein
Authors:Yang, X, Xu, M, Jiang, T, Fan, Z.
Deposit date:2013-11-20
Release date:2014-04-09
Last modified:2014-04-16
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Molecular mechanism for self-protection against the type VI secretion system in Vibrio cholerae.
Acta Crystallogr.,Sect.D, 70, 2014
3V69
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BU of 3v69 by Molmil
Filia-N crystal structure
Descriptor: Protein Filia
Authors:Wang, J, Xu, M, Zhu, K, Li, L, Liu, X.
Deposit date:2011-12-19
Release date:2012-02-15
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:The N-terminus of FILIA Forms an Atypical KH Domain with a Unique Extension Involved in Interaction with RNA.
Plos One, 7, 2012
8WY0
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BU of 8wy0 by Molmil
T cell receptor delta 2 gamma 9 with F283A, F290A, and F291A
Descriptor: CHOLESTEROL, Signal peptide,flag tag,T cell receptor delta variable 2,T cell receptor delta constant, Signal peptide,flag tag,T cell receptor gamma variable 9,T cell receptor gamma constant 1, ...
Authors:Xin, W, Huang, B, Chi, X, Liu, Y, Xu, M, Zhang, Y, Li, X, Su, Q, Zhou, Q.
Deposit date:2023-10-30
Release date:2024-05-08
Last modified:2024-06-19
Method:ELECTRON MICROSCOPY (3.8 Å)
Cite:Structures of human gamma delta T cell receptor-CD3 complex.
Nature, 630, 2024
8WYI
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BU of 8wyi by Molmil
T cell receptor delta 2 gamma 9 with TCRD TM domain chimera of TRAC
Descriptor: Signal peptide,flag tag,T cell receptor delta variable 2,T cell receptor delta constant,T cell receptor alpha chain constant,T cell receptor delta variable 2,T cell receptor delta constant,T cell receptor alpha chain constant, Signal peptide,flag tag,T cell receptor gamma variable 9,T cell receptor gamma constant 1,T cell receptor gamma variable 9,T cell receptor gamma constant 1, T-cell surface glycoprotein CD3 delta chain, ...
Authors:Xin, W, Huang, B, Chi, X, Liu, Y, Xu, M, Zhang, Y, Li, X, Su, Q, Zhou, Q.
Deposit date:2023-10-31
Release date:2024-05-08
Last modified:2024-06-19
Method:ELECTRON MICROSCOPY (3.9 Å)
Cite:Structures of human gamma delta T cell receptor-CD3 complex.
Nature, 630, 2024
8WXE
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BU of 8wxe by Molmil
Vgamma5Vdelta1 EH TCR-CD3 complex
Descriptor: CHOLESTEROL, Signal peptide,flag tag,T cell receptor delta variable 1,T cell receptor delta constant, Signal peptide,flag tag,T cell receptor gamma variable 5,T cell receptor gamma constant 1, ...
Authors:Xin, W, Huang, B, Chi, X, Xu, M, Zhang, Y, Li, X, Su, Q, Zhou, Q.
Deposit date:2023-10-28
Release date:2024-05-08
Last modified:2024-06-19
Method:ELECTRON MICROSCOPY (4 Å)
Cite:Structures of human gamma delta T cell receptor-CD3 complex.
Nature, 630, 2024
8YC0
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BU of 8yc0 by Molmil
T cell receptor V delta2 V gamma9 in GDN
Descriptor: CHOLESTEROL, T cell receptor delta variable 2,T cell receptor delta constant, T cell receptor gamma variable 9,T cell receptor gamma constant 1, ...
Authors:Xin, W, Huang, B, Chi, X, Xu, M, Zhang, Y, Li, X, Su, Q, Zhou, Q.
Deposit date:2024-02-17
Release date:2024-05-08
Last modified:2024-06-19
Method:ELECTRON MICROSCOPY (4.12 Å)
Cite:Structures of human gamma delta T cell receptor-CD3 complex.
Nature, 630, 2024
5X3P
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BU of 5x3p by Molmil
Crystal structure of the UBX domain of human UBXD7
Descriptor: UBX domain-containing protein 7
Authors:Jiang, T, Li, Z, Wang, Y, Xu, M.
Deposit date:2017-02-06
Release date:2017-03-22
Last modified:2017-04-05
Method:X-RAY DIFFRACTION (1.999 Å)
Cite:Crystal structures of the UBX domain of human UBXD7 and its complex with p97 ATPase
Biochem. Biophys. Res. Commun., 486, 2017
5X4L
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BU of 5x4l by Molmil
Crystal structure of the UBX domain of human UBXD7 in complex with p97 N domain
Descriptor: Transitional endoplasmic reticulum ATPase, UBX domain-containing protein 7
Authors:Jiang, T, Li, Z, Wang, Y, Xu, M.
Deposit date:2017-02-13
Release date:2017-03-22
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.402 Å)
Cite:Crystal structures of the UBX domain of human UBXD7 and its complex with p97 ATPase
Biochem. Biophys. Res. Commun., 486, 2017
3OLC
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BU of 3olc by Molmil
Crystal structure of the N-terminal region of TopBP1
Descriptor: DNA topoisomerase 2-binding protein 1
Authors:Huo, Y.G, Bai, L, Xu, M, Jiang, T.
Deposit date:2010-08-25
Release date:2011-03-30
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Crystal structure of the N-terminal region of human Topoisomerase II beta binding protein 1
Biochem.Biophys.Res.Commun., 401, 2010
4TQN
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BU of 4tqn by Molmil
Crystal structure of the bromodomain of human CREBBP in complex with UL04
Descriptor: 1,2-ETHANEDIOL, 3-[(5-acetyl-2-ethoxyphenyl)carbamoyl]benzoic acid, CREB-binding protein
Authors:Dong, J, Caflisch, A.
Deposit date:2014-06-11
Release date:2015-06-24
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Discovery of CREBBP Bromodomain Inhibitors by High-Throughput Docking and Hit Optimization Guided by Molecular Dynamics.
J.Med.Chem., 59, 2016
8HEH
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BU of 8heh by Molmil
Crystal structure of GCN5-related N-acetyltransferase 05790
Descriptor: COENZYME A, GLYCEROL, GNAT family N-acetyltransferase
Authors:Xu, M.X, Ran, T.T, Wang, W.
Deposit date:2022-11-08
Release date:2022-12-21
Last modified:2024-05-29
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:Crystal structure of prodigiosin binding protein PgbP, a GNAT family protein, in Serratia marcescens FS14.
Biochem.Biophys.Res.Commun., 640, 2022

225681

数据于2024-10-02公开中

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