8A2R
 
 | | Cryo-EM structure of F-actin in the Mg2+-ADP-BeF3- nucleotide state. | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, Actin, alpha skeletal muscle, ... | | Authors: | Oosterheert, W, Klink, B.U, Belyy, A, Pospich, S, Raunser, S. | | Deposit date: | 2022-06-06 | | Release date: | 2022-08-10 | | Last modified: | 2022-11-23 | | Method: | ELECTRON MICROSCOPY (2.17 Å) | | Cite: | Structural basis of actin filament assembly and aging.
Nature, 611, 2022
|
|
7ZGU
 | | Human NLRP3-deltaPYD hexamer | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, NACHT, LRR and PYD domains-containing protein 3 | | Authors: | Raisch, T, Machtens, D.A, Bresch, I.B, Eberhage, J, Prumbaum, D, Reubold, T.F, Raunser, S, Eschenburg, S. | | Deposit date: | 2022-04-04 | | Release date: | 2022-05-18 | | Method: | ELECTRON MICROSCOPY (3.4 Å) | | Cite: | Cryo-EM structure of the NEK7-independent NLRP3 inflammasome
To Be Published
|
|
7NEP
 | | Homology model of the in situ actomyosin complex from the A-band of mouse psoas muscle sarcomere in the rigor state | | Descriptor: | Actin, alpha skeletal muscle, Myosin light chain 1/3, ... | | Authors: | Wang, Z, Grange, M, Wagner, T, Kho, A.L, Gautel, M, Raunser, S. | | Deposit date: | 2021-02-04 | | Release date: | 2021-04-07 | | Last modified: | 2024-05-01 | | Method: | ELECTRON MICROSCOPY (10.2 Å) | | Cite: | The molecular basis for sarcomere organization in vertebrate skeletal muscle.
Cell, 184, 2021
|
|
7ND2
 | | Cryo-EM structure of the human FERRY complex | | Descriptor: | Glutamine amidotransferase-like class 1 domain-containing protein 1, Protein phosphatase 1 regulatory subunit 21, Quinone oxidoreductase-like protein 1 | | Authors: | Quentin, D, Klink, B.U, Raunser, S. | | Deposit date: | 2021-01-29 | | Release date: | 2022-03-02 | | Last modified: | 2023-06-14 | | Method: | ELECTRON MICROSCOPY (4 Å) | | Cite: | Structural basis of mRNA binding by the human FERRY Rab5 effector complex.
Mol.Cell, 83, 2023
|
|
6FHL
 | | Cryo-EM structure of F-actin in complex with ADP-Pi | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, Actin, alpha skeletal muscle, ... | | Authors: | Merino, F, Pospich, S, Funk, J, Wagner, T, Kuellmer, F, Arndt, H.-D, Bieling, P, Raunser, S. | | Deposit date: | 2018-01-15 | | Release date: | 2018-06-13 | | Last modified: | 2018-08-29 | | Method: | ELECTRON MICROSCOPY (3.3 Å) | | Cite: | Structural transitions of F-actin upon ATP hydrolysis at near-atomic resolution revealed by cryo-EM.
Nat. Struct. Mol. Biol., 25, 2018
|
|
6H6G
 | | Crystal Structure of TcdB2-TccC3 without hypervariable C-terminal region | | Descriptor: | TcdB2,TccC3 | | Authors: | Gatsogiannis, C, Merino, F, Roderer, D, Balchin, D, Schubert, E, Kuhlee, A, Hayer-Hartl, M, Raunser, S. | | Deposit date: | 2018-07-27 | | Release date: | 2018-10-03 | | Last modified: | 2024-01-17 | | Method: | X-RAY DIFFRACTION (3.004 Å) | | Cite: | Tc toxin activation requires unfolding and refolding of a beta-propeller.
Nature, 563, 2018
|
|
6H6E
 | | PTC3 holotoxin complex from Photorhabdus luminecens in prepore state (TcdA1, TcdB2, TccC3) | | Descriptor: | TcdA1, TcdB2,TccC3 | | Authors: | Gatsogiannis, C, Merino, F, Roderer, D, Balchin, D, Schubert, E, Kuhlee, A, Hayer-Hartl, M, Raunser, S. | | Deposit date: | 2018-07-27 | | Release date: | 2018-10-03 | | Last modified: | 2024-05-15 | | Method: | ELECTRON MICROSCOPY (3.95 Å) | | Cite: | Tc toxin activation requires unfolding and refolding of a beta-propeller.
Nature, 563, 2018
|
|
6H3L
 | |
8P51
 | |
8P52
 | |
8P50
 | | Photorhabdus luminescens Makes caterpillars floppy (Mcf) toxin with the C-terminal deletion in complex with Arf3 | | Descriptor: | ADP-ribosylation factor 3, GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ... | | Authors: | Belyy, A, Heilen, P, Hofnagel, O, Raunser, S. | | Deposit date: | 2023-05-23 | | Release date: | 2023-11-01 | | Last modified: | 2023-12-27 | | Method: | ELECTRON MICROSCOPY (4.04 Å) | | Cite: | Structure and activation mechanism of the Makes caterpillars floppy 1 toxin.
Nat Commun, 14, 2023
|
|
8OI6
 | | Cryo-EM structure of the undecorated barbed end of filamentous beta/gamma actin | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, Actin, cytoplasmic 1, ... | | Authors: | Oosterheert, W, Blanc, F.E.C, Roy, A, Belyy, A, Hofnagel, O, Hummer, G, Bieling, P, Raunser, S. | | Deposit date: | 2023-03-22 | | Release date: | 2023-08-09 | | Last modified: | 2023-11-22 | | Method: | ELECTRON MICROSCOPY (3.59 Å) | | Cite: | Molecular mechanisms of inorganic-phosphate release from the core and barbed end of actin filaments.
Nat.Struct.Mol.Biol., 30, 2023
|
|
8OID
 | | Cryo-EM structure of ADP-bound, filamentous beta-actin harboring the N111S mutation | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, Actin, cytoplasmic 1, ... | | Authors: | Oosterheert, W, Blanc, F.E.C, Roy, A, Belyy, A, Hofnagel, O, Hummer, G, Bieling, P, Raunser, S. | | Deposit date: | 2023-03-22 | | Release date: | 2023-08-09 | | Last modified: | 2023-11-22 | | Method: | ELECTRON MICROSCOPY (2.3 Å) | | Cite: | Molecular mechanisms of inorganic-phosphate release from the core and barbed end of actin filaments.
Nat.Struct.Mol.Biol., 30, 2023
|
|
8OI8
 | | Cryo-EM structure of ADP-bound, filamentous beta-actin harboring the R183W mutation | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, Actin, cytoplasmic 1, ... | | Authors: | Oosterheert, W, Blanc, F.E.C, Roy, A, Belyy, A, Hofnagel, O, Hummer, G, Bieling, P, Raunser, S. | | Deposit date: | 2023-03-22 | | Release date: | 2023-08-16 | | Last modified: | 2023-11-22 | | Method: | ELECTRON MICROSCOPY (2.28 Å) | | Cite: | Molecular mechanisms of inorganic-phosphate release from the core and barbed end of actin filaments.
Nat.Struct.Mol.Biol., 30, 2023
|
|
4O9Y
 | | Crystal Structure of TcdA1 | | Descriptor: | TcdA1 | | Authors: | Meusch, D, Gatsogiannis, C, Efremov, R.G, Lang, A.E, Hofnagel, O, Vetter, I.R, Aktories, K, Raunser, S. | | Deposit date: | 2014-01-03 | | Release date: | 2014-02-26 | | Last modified: | 2024-02-28 | | Method: | X-RAY DIFFRACTION (3.502 Å) | | Cite: | Mechanism of Tc toxin action revealed in molecular detail.
Nature, 508, 2014
|
|
4O9X
 | | Crystal Structure of TcdB2-TccC3 | | Descriptor: | MERCURY (II) ION, TcdB2, TccC3 | | Authors: | Meusch, D, Gatsogiannis, C, Efremov, R.G, Lang, A.E, Hofnagel, O, Vetter, I.R, Aktories, K, Raunser, S. | | Deposit date: | 2014-01-03 | | Release date: | 2014-02-26 | | Last modified: | 2024-02-28 | | Method: | X-RAY DIFFRACTION (2.17 Å) | | Cite: | Mechanism of Tc toxin action revealed in molecular detail.
Nature, 508, 2014
|
|
7Q5P
 | | Structure of VgrG1 from Pseudomonas protegens. | | Descriptor: | Type VI secretion protein VgrG | | Authors: | Guenther, P, Quentin, D, Ahmad, S, Sachar, K, Gatsogiannis, C, Whitney, J.C, Raunser, S. | | Deposit date: | 2021-11-04 | | Release date: | 2021-12-15 | | Last modified: | 2022-02-02 | | Method: | ELECTRON MICROSCOPY (3.3 Å) | | Cite: | Structure of a bacterial Rhs effector exported by the type VI secretion system.
Plos Pathog., 18, 2022
|
|
7AHN
 | | Cryo-EM structure of F-actin stabilized by cis-optoJASP-8 | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, Actin, alpha skeletal muscle, ... | | Authors: | Pospich, S, Raunser, S. | | Deposit date: | 2020-09-24 | | Release date: | 2021-01-27 | | Last modified: | 2021-04-14 | | Method: | ELECTRON MICROSCOPY (2.9 Å) | | Cite: | Cryo-EM Resolves Molecular Recognition Of An Optojasp Photoswitch Bound To Actin Filaments In Both Switch States.
Angew.Chem.Int.Ed.Engl., 60, 2021
|
|
7AHQ
 | | Cryo-EM structure of F-actin stabilized by trans-optoJASP-8 | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, Actin, alpha skeletal muscle, ... | | Authors: | Pospich, S, Raunser, S. | | Deposit date: | 2020-09-25 | | Release date: | 2021-01-27 | | Last modified: | 2021-04-14 | | Method: | ELECTRON MICROSCOPY (3.6 Å) | | Cite: | Cryo-EM Resolves Molecular Recognition Of An Optojasp Photoswitch Bound To Actin Filaments In Both Switch States.
Angew.Chem.Int.Ed.Engl., 60, 2021
|
|
8S3E
 | | Structure of rabbit Slo1 in complex with gamma1/LRRC26 | | Descriptor: | (4S,7R)-4-HYDROXY-N,N,N-TRIMETHYL-9-OXO-7-[(PALMITOYLOXY)METHYL]-3,5,8-TRIOXA-4-PHOSPHAHEXACOSAN-1-AMINIUM 4-OXIDE, CALCIUM ION, CHOLESTEROL, ... | | Authors: | Redhardt, M, Raunser, S, Raisch, T. | | Deposit date: | 2024-02-20 | | Release date: | 2024-04-10 | | Last modified: | 2024-05-01 | | Method: | ELECTRON MICROSCOPY (2.39 Å) | | Cite: | Cryo-EM structure of the Slo1 potassium channel with the auxiliary gamma 1 subunit suggests a mechanism for depolarization-independent activation.
Febs Lett., 598, 2024
|
|
4A7F
 | | Structure of the Actin-Tropomyosin-Myosin Complex (rigor ATM 3) | | Descriptor: | ACTIN, ALPHA SKELETAL MUSCLE, ADENOSINE-5'-DIPHOSPHATE, ... | | Authors: | Behrmann, E, Mueller, M, Penczek, P.A, Mannherz, H.G, Manstein, D.J, Raunser, S. | | Deposit date: | 2011-11-14 | | Release date: | 2012-08-01 | | Last modified: | 2017-08-30 | | Method: | ELECTRON MICROSCOPY (7.7 Å) | | Cite: | Structure of the Rigor Actin-Tropomyosin-Myosin Complex.
Cell(Cambridge,Mass.), 150, 2012
|
|
4A7L
 | | Structure of the Actin-Tropomyosin-Myosin Complex (rigor ATM 1) | | Descriptor: | ACTIN, ALPHA SKELETON MUSCLE, ADENOSINE-5'-DIPHOSPHATE, ... | | Authors: | Behrmann, E, Mueller, M, Penczek, P.A, Mannherz, H.G, Manstein, D.J, Raunser, S. | | Deposit date: | 2011-11-14 | | Release date: | 2012-08-01 | | Last modified: | 2019-10-23 | | Method: | ELECTRON MICROSCOPY (8.1 Å) | | Cite: | Structure of the Rigor Actin-Tropomyosin-Myosin Complex.
Cell(Cambridge,Mass.), 150, 2012
|
|
4A7N
 | | Structure of bare F-actin filaments obtained from the same sample as the Actin-Tropomyosin-Myosin Complex | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, CALCIUM ION, F-ACTIN | | Authors: | Behrmann, E, Mueller, M, Penczek, P.A, Mannherz, H.G, Manstein, D.J, Raunser, S. | | Deposit date: | 2011-11-14 | | Release date: | 2012-08-01 | | Last modified: | 2017-08-30 | | Method: | ELECTRON MICROSCOPY (8.9 Å) | | Cite: | Structure of the Rigor Actin-Tropomyosin-Myosin Complex.
Cell(Cambridge,Mass.), 150, 2012
|
|
4A7H
 | | Structure of the Actin-Tropomyosin-Myosin Complex (rigor ATM 2) | | Descriptor: | ACTIN, ALPHA SKELETAL MUSCLE, ADENOSINE-5'-DIPHOSPHATE, ... | | Authors: | Behrmann, E, Mueller, M, Penczek, P.A, Mannherz, H.G, Manstein, D.J, Raunser, S. | | Deposit date: | 2011-11-14 | | Release date: | 2012-08-01 | | Last modified: | 2017-08-30 | | Method: | ELECTRON MICROSCOPY (7.8 Å) | | Cite: | Structure of the Rigor Actin-Tropomyosin-Myosin Complex.
Cell(Cambridge,Mass.), 150, 2012
|
|
6G1K
 | | Electron cryo-microscopy structure of the canonical TRPC4 ion channel | | Descriptor: | (2R)-3-(phosphonooxy)propane-1,2-diyl dihexanoate, CHOLESTEROL HEMISUCCINATE, Transient receptor potential cation channel subfamily c member 4a | | Authors: | Vinayagam, D, Mager, T, Apelbaum, A, Bothe, A, Merino, F, Hofnagel, O, Gatsogiannis, C, Raunser, S. | | Deposit date: | 2018-03-21 | | Release date: | 2018-05-02 | | Last modified: | 2018-08-01 | | Method: | ELECTRON MICROSCOPY (3.6 Å) | | Cite: | Electron cryo-microscopy structure of the canonical TRPC4 ion channel.
Elife, 7, 2018
|
|
