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8G6V
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BU of 8g6v by Molmil
Hepatitis B virus capsid bound to importin alpha1/beta heterodimer
Descriptor: Core protein Cp183
Authors:Yang, R, Cingolani, G.
Deposit date:2023-02-16
Release date:2024-01-24
Last modified:2024-08-21
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:Structural basis for nuclear import of hepatitis B virus (HBV) nucleocapsid core.
Sci Adv, 10, 2024
8G8Y
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BU of 8g8y by Molmil
Hepatitis B virus capsid bound to importin alpha1
Descriptor: Core protein Cp183
Authors:Yang, R, Cingolani, G.
Deposit date:2023-02-20
Release date:2024-01-31
Last modified:2024-08-21
Method:ELECTRON MICROSCOPY (3.8 Å)
Cite:Structural basis for nuclear import of hepatitis B virus (HBV) nucleocapsid core.
Sci Adv, 10, 2024
8GCN
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BU of 8gcn by Molmil
CRYO-EM STRUCTURE OF IMPORTIN ALPHA1/BETA HETERODIMER
Descriptor: Importin subunit alpha-1, Importin subunit beta-1
Authors:Ko, Y, Cingolani, G.
Deposit date:2023-03-02
Release date:2024-03-06
Method:ELECTRON MICROSCOPY (3.95 Å)
Cite:CRYO-EM STRUCTURE OF IMPORTIN ALPHA1/BETA HETERODIMER
To Be Published
4UAF
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BU of 4uaf by Molmil
Importin alpha 1 delta IBB in complex with Influenza PB2 nuclear localization domain
Descriptor: Importin subunit alpha-1, PHOSPHATE ION, Polymerase basic protein 2
Authors:Pumroy, R.A, Cingolani, G.
Deposit date:2014-08-08
Release date:2015-02-04
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (1.698 Å)
Cite:Molecular Determinants for Nuclear Import of Influenza A PB2 by Importin alpha Isoforms 3 and 7.
Structure, 23, 2015
4UAM
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BU of 4uam by Molmil
1.8 Angstrom crystal structure of IMP-1 metallo-beta-lactamase with a mixed iron-zinc center in the active site
Descriptor: CITRATE ANION, FE (III) ION, IMP-1 metallo-beta-lactamase, ...
Authors:Carruthers, T.J, Carr, P.D, Jackson, C.J, Otting, G.
Deposit date:2014-08-11
Release date:2014-09-17
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Iron(III) Located in the Dinuclear Metallo-beta-Lactamase IMP-1 by Pseudocontact Shifts.
Angew.Chem.Int.Ed.Engl., 53, 2014
4UAD
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BU of 4uad by Molmil
Importin alpha 7 delta IBB in complex with Influenza PB2 Nuclear Localization Domain
Descriptor: Importin subunit alpha-7, Polymerase basic protein 2
Authors:Pumroy, R.A, Cingolani, G.
Deposit date:2014-08-08
Release date:2015-02-04
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (2.42 Å)
Cite:Molecular Determinants for Nuclear Import of Influenza A PB2 by Importin alpha Isoforms 3 and 7.
Structure, 23, 2015
4UAE
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BU of 4uae by Molmil
Importin alpha 3 delta IBB in complex with Influenza PB2 Nuclear Localization Domain
Descriptor: Importin subunit alpha-3, Polymerase basic protein 2, SULFATE ION
Authors:Pumroy, R.A, Cingolani, G.
Deposit date:2014-08-08
Release date:2015-02-04
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Molecular Determinants for Nuclear Import of Influenza A PB2 by Importin alpha Isoforms 3 and 7.
Structure, 23, 2015
5HIE
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BU of 5hie by Molmil
BRAF Kinase domain b3aC loop deletion mutant in complex with dabrafenib
Descriptor: Dabrafenib, Serine/threonine-protein kinase B-raf
Authors:Whalen, D.M, Foster, S.A, Ozen, A, Wongchenko, M, Yin, J, Schaefer, G, Mayfield, J, Chmielecki, J, Stephens, P, Albacker, L, Yan, Y, Song, K, Hatzivassiliou, G, Eigenbrot, C, Yu, C, Shaw, A.S, Manning, G, Skelton, N.J, Hymowitz, S.G, Malek, S.
Deposit date:2016-01-11
Release date:2016-04-06
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (3 Å)
Cite:Activation Mechanism of Oncogenic Deletion Mutations in BRAF, EGFR, and HER2.
Cancer Cell, 29, 2016
4XZR
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BU of 4xzr by Molmil
Structure of yeast importin a bound to the membrane protein Nuclear Localization Signal sequence of INM protein Heh1
Descriptor: Importin subunit alpha, Inner nuclear membrane protein SRC1
Authors:Lokareddy, R.K, Cingolani, G.
Deposit date:2015-02-04
Release date:2015-06-17
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:Distinctive Properties of the Nuclear Localization Signals of Inner Nuclear Membrane Proteins Heh1 and Heh2.
Structure, 23, 2015
4YI0
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BU of 4yi0 by Molmil
Structure of mouse importin a1 bound to Pom121NLS
Descriptor: Importin subunit alpha-1, Nuclear envelope pore membrane protein POM 121
Authors:Lokareddy, R.K, Cingolani, G.
Deposit date:2015-02-27
Release date:2016-01-13
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.806 Å)
Cite:Mammalian Pom121 and yeast Heh2 share IBB-like NLSs that support targeting to the inner nuclear membrane
To Be Published
4ZKU
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BU of 4zku by Molmil
P22 Tail Needle Gp26 crystallized at pH 10.0
Descriptor: CALCIUM ION, CHLORIDE ION, Tail needle protein gp26
Authors:Sankhala, R.S, Cingolani, G.
Deposit date:2015-04-30
Release date:2015-06-10
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structural Plasticity of the Protein Plug That Traps Newly Packaged Genomes in Podoviridae Virions.
J.Biol.Chem., 291, 2016
6O6I
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BU of 6o6i by Molmil
Endoplasmic reticulum protein 29 (ERp29) C-terminal domain: Structure Determination from Backbone Amide Pseudocontact Shifts Generated by Double-histidine Cobalt Tags
Descriptor: Endoplasmic reticulum resident protein 29
Authors:Bahramzadeh, A, Huber, T, Otting, G.
Deposit date:2019-03-06
Release date:2019-07-24
Last modified:2024-05-01
Method:SOLUTION NMR
Cite:Three-Dimensional Protein Structure Determination Using Pseudocontact Shifts of Backbone Amide Protons Generated by Double-Histidine Co2+-Binding Motifs at Multiple Sites.
Biochemistry, 58, 2019
8G83
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BU of 8g83 by Molmil
Structure of NAD+ consuming protein Acinetobacter baumannii TIR domain
Descriptor: NAD(+) hydrolase AbTIR
Authors:Klontz, E.H, Wang, Y, Glendening, G, Carr, J, Tsibouris, T, Buddula, S, Nallar, S, Soares, A, Snyder, G.A.
Deposit date:2023-02-17
Release date:2023-10-11
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (3.03 Å)
Cite:The structure of NAD + consuming protein Acinetobacter baumannii TIR domain shows unique kinetics and conformations.
J.Biol.Chem., 299, 2023
5HUY
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BU of 5huy by Molmil
Structure of HCMV Small Terminase NLS bound to importin alpha
Descriptor: HCMV small terminase, Importin subunit alpha-1
Authors:Sankhala, R.S, Lokareddy, R.K, Cingolani, G.
Deposit date:2016-01-28
Release date:2016-03-16
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.979 Å)
Cite:Divergent Evolution of Nuclear Localization Signal Sequences in Herpesvirus Terminase Subunits.
J.Biol.Chem., 291, 2016
5HUW
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BU of 5huw by Molmil
Structure of HSV-1 Large Terminase NLS bound to importin alpha
Descriptor: HSV1 large terminase NLS, Importin subunit alpha-1
Authors:Sankhala, R.S, Lokareddy, R.K, Cingolani, G.
Deposit date:2016-01-27
Release date:2016-03-09
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Divergent Evolution of Nuclear Localization Signal Sequences in Herpesvirus Terminase Subunits.
J.Biol.Chem., 291, 2016
8EON
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BU of 8eon by Molmil
Pseudomonas phage E217 baseplate complex
Descriptor: Baseplate component gp33, Baseplate component gp34, Baseplate component gp36, ...
Authors:Li, F, Cingolani, G, Hou, C.
Deposit date:2022-10-03
Release date:2023-07-26
Last modified:2024-06-19
Method:ELECTRON MICROSCOPY (3.6 Å)
Cite:High-resolution cryo-EM structure of the Pseudomonas bacteriophage E217.
Nat Commun, 14, 2023
8ENV
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BU of 8env by Molmil
In situ cryo-EM structure of Pseudomonas phage E217 tail baseplate in C6 map
Descriptor: Baseplate_J domain-containing protein gp44, Ripcord gp36, Sheath initiator gp34, ...
Authors:Li, F, Cingolani, G, Hou, C.
Deposit date:2022-09-30
Release date:2023-07-26
Last modified:2024-06-19
Method:ELECTRON MICROSCOPY (3.42 Å)
Cite:High-resolution cryo-EM structure of the Pseudomonas bacteriophage E217.
Nat Commun, 14, 2023
5MW2
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BU of 5mw2 by Molmil
CRYSTAL STRUCTURE OF BCL-6 BTB-domain with BI-3802
Descriptor: 2-[6-[[5-chloranyl-2-[(3~{S},5~{R})-3,5-dimethylpiperidin-1-yl]pyrimidin-4-yl]amino]-1-methyl-2-oxidanylidene-quinolin-3-yl]oxy-~{N}-methyl-ethanamide, B-cell lymphoma 6 protein
Authors:Bader, G, Flotzinger, G, Weiss-Puxbaum, A, Zoephel, A.
Deposit date:2017-01-18
Release date:2017-10-04
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (2.35 Å)
Cite:Chemically Induced Degradation of the Oncogenic Transcription Factor BCL6.
Cell Rep, 20, 2017
8FUV
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BU of 8fuv by Molmil
Pseudomonas phage E217 extended sheath and tail tube
Descriptor: Sheath protein gp31, Tail fiber protein gp32
Authors:Li, F, Cingolani, G, Hou, C.
Deposit date:2023-01-18
Release date:2023-07-26
Last modified:2024-06-19
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:High-resolution cryo-EM structure of the Pseudomonas bacteriophage E217.
Nat Commun, 14, 2023
8FVG
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BU of 8fvg by Molmil
Pseudomonas phage E217 contracted sheath
Descriptor: Sheath protein gp31
Authors:Li, F, Cingolani, G, Hou, C.
Deposit date:2023-01-18
Release date:2023-07-26
Last modified:2024-06-19
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:High-resolution cryo-EM structure of the Pseudomonas bacteriophage E217.
Nat Commun, 14, 2023
8FRS
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BU of 8frs by Molmil
Pseudomonas phage E217 5-fold vertex (capsid and decorating proteins)
Descriptor: Major structural protein, Structural protein gp24
Authors:Li, F, Cingolani, G, Hou, C.
Deposit date:2023-01-08
Release date:2023-07-26
Last modified:2024-06-19
Method:ELECTRON MICROSCOPY (3.96 Å)
Cite:High-resolution cryo-EM structure of the Pseudomonas bacteriophage E217.
Nat Commun, 14, 2023
8FVH
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BU of 8fvh by Molmil
Pseudomonas phage E217 neck (portal, head-to-tail connector, collar and gateway proteins)
Descriptor: E217 collar protein gp28, E217 gateway protein gp29, E217 head-to-tail connector protein gp27, ...
Authors:Li, F, Cingolani, G, Hou, C.
Deposit date:2023-01-18
Release date:2023-07-26
Last modified:2024-06-19
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:High-resolution cryo-EM structure of the Pseudomonas bacteriophage E217.
Nat Commun, 14, 2023
1AHD
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BU of 1ahd by Molmil
DETERMINATION OF THE NMR SOLUTION STRUCTURE OF AN ANTENNAPEDIA HOMEODOMAIN-DNA COMPLEX
Descriptor: DNA (5'-D(*CP*TP*CP*TP*AP*AP*TP*GP*GP*CP*TP*TP*TP*C)-3'), DNA (5'-D(*GP*AP*AP*AP*GP*CP*CP*AP*TP*TP*AP*GP*AP*G)-3'), Homeotic protein antennapedia
Authors:Billeter, M, Qian, Y.Q, Otting, G, Muller, M, Gehring, W.J, Wuthrich, K.
Deposit date:1993-04-02
Release date:1993-10-31
Last modified:2024-04-10
Method:SOLUTION NMR
Cite:Determination of the nuclear magnetic resonance solution structure of an Antennapedia homeodomain-DNA complex.
J.Mol.Biol., 234, 1993
5MWD
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BU of 5mwd by Molmil
Crystal structure of the BCL6 BTB-domain with compound 2
Descriptor: 5-[[5-chloranyl-2-(3,5-dimethylpyrazol-1-yl)pyrimidin-4-yl]amino]-1,3-dihydroindol-2-one, B-cell lymphoma 6 protein
Authors:Bader, G, Flotzinger, G, Weiss-Puxbaum, A, Zoephel, A.
Deposit date:2017-01-18
Release date:2017-10-04
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Chemically Induced Degradation of the Oncogenic Transcription Factor BCL6.
Cell Rep, 20, 2017
5JJ1
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BU of 5jj1 by Molmil
Structure of the Immature Procapsid Conformation of P22 Portal Protein
Descriptor: Portal protein
Authors:Lokareddy, R.K, Cingolani, G.
Deposit date:2016-04-22
Release date:2017-02-08
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (3.3 Å)
Cite:Portal protein functions akin to a DNA-sensor that couples genome-packaging to icosahedral capsid maturation.
Nat Commun, 8, 2017

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数据于2024-09-04公开中

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