6L0A
| Crystal structure of dihydroorotase in complex with malate at pH7 from Saccharomyces cerevisiae | Descriptor: | (2S)-2-hydroxybutanedioic acid, Dihydroorotase, ZINC ION | Authors: | Guan, H.H, Huang, Y.H, Huang, C.Y, Chen, C.J. | Deposit date: | 2019-09-26 | Release date: | 2020-12-02 | Last modified: | 2021-12-15 | Method: | X-RAY DIFFRACTION (1.79 Å) | Cite: | Structural Analysis of Saccharomyces cerevisiae Dihydroorotase Reveals Molecular Insights into the Tetramerization Mechanism Molecules, 2021
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6L0G
| Crystal structure of dihydroorotase in complex with malate at pH6 from Saccharomyces cerevisiae | Descriptor: | (2S)-2-hydroxybutanedioic acid, Dihydroorotase, ZINC ION | Authors: | Guan, H.H, Huang, Y.H, Huang, C.Y, Chen, C.J. | Deposit date: | 2019-09-26 | Release date: | 2020-12-02 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.053 Å) | Cite: | Structural basis for the interaction modes of dihydroorotase with the anticancer drugs 5-fluorouracil and 5-aminouracil. Biochem.Biophys.Res.Commun., 551, 2021
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7CA0
| Crystal structure of dihydroorotase in complex with 5-fluoroorotic acid from Saccharomyces cerevisiae | Descriptor: | 5-FLUORO-2,6-DIOXO-1,2,3,6-TETRAHYDROPYRIMIDINE-4-CARBOXYLIC ACID, Dihydroorotase, ZINC ION | Authors: | Guan, H.H, Huang, Y.H, Huang, C.Y, Chen, C.J. | Deposit date: | 2020-06-08 | Release date: | 2021-06-09 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Complexed Crystal Structure of Saccharomyces cerevisiae Dihydroorotase with Inhibitor 5-Fluoroorotate Reveals a New Binding Mode. Bioinorg Chem Appl, 2021, 2021
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7CA1
| Crystal structure of dihydroorotase in complex with plumbagin from Saccharomyces cerevisiae | Descriptor: | (2S)-2-hydroxybutanedioic acid, 5-hydroxy-2-methylnaphthalene-1,4-dione, Dihydroorotase, ... | Authors: | Guan, H.H, Huang, Y.H, Huang, C.Y, Chen, C.J. | Deposit date: | 2020-06-08 | Release date: | 2021-06-09 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (3.6 Å) | Cite: | Plumbagin, a Natural Product with Potent Anticancer Activities, Binds to and Inhibits Dihydroorotase, a Key Enzyme in Pyrimidine Biosynthesis. Int J Mol Sci, 22, 2021
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7F2N
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7F25
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7FBP
| FXIIa-cMCoFx1 complex | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-3)-alpha-D-mannopyranose-(1-3)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Coagulation factor XIIa light chain, cMCoFx1 | Authors: | Sengoku, T, Liu, W, de Veer, S.J, Huang, Y.H, Okada, C, Zdenek, C.N, Fry, B.G, Swedberg, J.E, Passioura, T, Craik, D.J, Suga, H, Ogata, K. | Deposit date: | 2021-07-12 | Release date: | 2021-11-10 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.99 Å) | Cite: | An Ultrapotent and Selective Cyclic Peptide Inhibitor of Human beta-Factor XIIa in a Cyclotide Scaffold. J.Am.Chem.Soc., 143, 2021
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8HFD
| Crystal structure of allantoinase from E. coli BL21 | Descriptor: | Allantoinase, DI(HYDROXYETHYL)ETHER, ZINC ION | Authors: | Lin, E.S, Huang, H.Y, Yang, P.C, Liu, H.W, Huang, C.Y. | Deposit date: | 2022-11-10 | Release date: | 2023-10-18 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (2.07 Å) | Cite: | Crystal Structure of Allantoinase from Escherichia coli BL21: A Molecular Insight into a Role of the Active Site Loops in Catalysis. Molecules, 28, 2023
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2MT8
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4N74
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5YUN
| Crystal structure of SSB complexed with myc | Descriptor: | 3,5,7-TRIHYDROXY-2-(3,4,5-TRIHYDROXYPHENYL)-4H-CHROMEN-4-ONE, Single-stranded DNA-binding protein | Authors: | Huang, Y.H, Huang, C.Y. | Deposit date: | 2017-11-22 | Release date: | 2018-10-10 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.67 Å) | Cite: | Crystal structure of SSB complexed with inhibitor myricetin. Biochem. Biophys. Res. Commun., 504, 2018
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5MS0
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6ZCA
| Structure of the B. subtilis RNA POLYMERASE in complex with HelD (monomer) | Descriptor: | DNA helicase, DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ... | Authors: | Pei, H.-P, Hilal, T, Huang, Y.-H, Said, N, Loll, B, Wahl, M.C. | Deposit date: | 2020-06-10 | Release date: | 2020-10-14 | Last modified: | 2024-05-15 | Method: | ELECTRON MICROSCOPY (4.2 Å) | Cite: | The delta subunit and NTPase HelD institute a two-pronged mechanism for RNA polymerase recycling. Nat Commun, 11, 2020
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6ZFB
| Structure of the B. subtilis RNA POLYMERASE in complex with HelD (dimer) | Descriptor: | DNA helicase, DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ... | Authors: | Pei, H.-P, Hilal, T, Huang, Y.-H, Said, N, Loll, B, Wahl, M.C. | Deposit date: | 2020-06-17 | Release date: | 2020-10-14 | Last modified: | 2024-05-15 | Method: | ELECTRON MICROSCOPY (3.9 Å) | Cite: | The delta subunit and NTPase HelD institute a two-pronged mechanism for RNA polymerase recycling. Nat Commun, 11, 2020
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4APV
| The Klebsiella pneumoniae primosomal PriB protein: identification, crystal structure, and ssDNA binding mode | Descriptor: | PRIMOSOMAL REPLICATION PROTEIN N | Authors: | Lo, Y.H, Huang, Y.H, Hsiao, C.D, Huang, C.Y. | Deposit date: | 2012-04-06 | Release date: | 2012-04-25 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2.095 Å) | Cite: | Crystal Structure and DNA-Binding Mode of Klebsiella Pneumoniae Primosomal Prib Protein. Genes Cells, 17, 2012
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6GOV
| Structure of THE RNA POLYMERASE LAMBDA-BASED ANTITERMINATION COMPLEX | Descriptor: | 30S ribosomal protein S10, Antitermination protein N, DNA (I), ... | Authors: | Loll, B, Krupp, F, Said, N, Huang, Y, Buerger, J, Mielke, T, Spahn, C.M.T, Wahl, M.C. | Deposit date: | 2018-06-04 | Release date: | 2019-02-13 | Last modified: | 2019-12-18 | Method: | ELECTRON MICROSCOPY (3.7 Å) | Cite: | Structural Basis for the Action of an All-Purpose Transcription Anti-termination Factor. Mol.Cell, 74, 2019
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6PI2
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6PIN
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6PI3
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6PIO
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6PIP
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8CUN
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8CWA
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8CTO
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5LM7
| Crystal structure of the lambda N-Nus factor complex | Descriptor: | 30S ribosomal protein S10, Antitermination protein N, N utilization substance protein B homolog, ... | Authors: | Said, N, Santos, K, Weber, G, Wahl, M.C. | Deposit date: | 2016-07-29 | Release date: | 2017-04-05 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (3.35 Å) | Cite: | Structural basis for lambda N-dependent processive transcription antitermination. Nat Microbiol, 2, 2017
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