6XSW
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6xsw by Molmil](/molmil-images/mine/6xsw) | Structure of the Notch3 NRR in complex with an antibody Fab Fragment | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Anti-N3 Fab Heavy Chain, ... | Authors: | Bard, J. | Deposit date: | 2020-07-16 | Release date: | 2021-07-21 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2.98 Å) | Cite: | NOTCH3-targeted antibody drug conjugates regress tumors by inducing apoptosis in receptor cells and through transendocytosis into ligand cells. Cell Rep Med, 2, 2021
|
|
7XPZ
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7xpz by Molmil](/molmil-images/mine/7xpz) | Structure of Apo-hSLC19A1 | Descriptor: | Reduced folate transporter | Authors: | Zhang, Q.X, Zhang, X.Y, Zhu, Y.L, Sun, P.P, Gao, A, Zhang, L.G, Gao, P. | Deposit date: | 2022-05-06 | Release date: | 2022-10-05 | Last modified: | 2022-12-14 | Method: | ELECTRON MICROSCOPY (3.4 Å) | Cite: | Recognition of cyclic dinucleotides and folates by human SLC19A1. Nature, 612, 2022
|
|
7XQ2
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7xq2 by Molmil](/molmil-images/mine/7xq2) | Structure of hSLC19A1+2'3'-cGAMP | Descriptor: | Reduced folate transporter, cGAMP | Authors: | Zhang, Q.X, Zhang, X.Y, Zhu, Y.L, Sun, P.P, Gao, A, Zhang, L.G, Gao, P. | Deposit date: | 2022-05-06 | Release date: | 2022-10-05 | Last modified: | 2022-12-14 | Method: | ELECTRON MICROSCOPY (3.3 Å) | Cite: | Recognition of cyclic dinucleotides and folates by human SLC19A1. Nature, 612, 2022
|
|
7XQ0
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7xq0 by Molmil](/molmil-images/mine/7xq0) | Structure of hSLC19A1+3'3'-CDA | Descriptor: | (2R,3R,3aS,5R,7aR,9R,10R,10aS,12R,14aR)-2,9-bis(6-amino-9H-purin-9-yl)octahydro-2H,7H-difuro[3,2-d:3',2'-j][1,3,7,9,2,8 ]tetraoxadiphosphacyclododecine-3,5,10,12-tetrol 5,12-dioxide, Reduced folate transporter | Authors: | Zhang, Q.X, Zhang, X.Y, Zhu, Y.L, Sun, P.P, Gao, A, Zhang, L.G, Gao, P. | Deposit date: | 2022-05-06 | Release date: | 2022-10-05 | Last modified: | 2022-12-14 | Method: | ELECTRON MICROSCOPY (3 Å) | Cite: | Recognition of cyclic dinucleotides and folates by human SLC19A1. Nature, 612, 2022
|
|
7XQ1
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7xq1 by Molmil](/molmil-images/mine/7xq1) | Structure of hSLC19A1+2'3'-CDAS | Descriptor: | (1~{R},3~{S},6~{R},8~{R},9~{R},10~{S},12~{S},15~{R},17~{R},18~{R})-8,17-bis(6-aminopurin-9-yl)-3,12-bis(oxidanylidene)-3,12-bis(sulfanyl)-2,4,7,11,13,16-hexaoxa-3$l^{5},12$l^{5}-diphosphatricyclo[13.2.1.0^{6,10}]octadecane-9,18-diol, Reduced folate transporter | Authors: | Zhang, Q.X, Zhang, X.Y, Zhu, Y.L, Sun, P.P, Gao, A, Zhang, L.G, Gao, P. | Deposit date: | 2022-05-06 | Release date: | 2022-10-05 | Last modified: | 2022-12-14 | Method: | ELECTRON MICROSCOPY (3.4 Å) | Cite: | Recognition of cyclic dinucleotides and folates by human SLC19A1. Nature, 612, 2022
|
|
1YIC
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1yic by Molmil](/molmil-images/mine/1yic) | THE OXIDIZED SACCHAROMYCES CEREVISIAE ISO-1-CYTOCHROME C, NMR, 20 STRUCTURES | Descriptor: | CYTOCHROME C, ISO-1, HEME C | Authors: | Banci, L, Bertini, I, Bren, K.L, Gray, H.B, Sompornpisut, P, Turano, P. | Deposit date: | 1997-02-18 | Release date: | 1997-07-23 | Last modified: | 2021-11-03 | Method: | SOLUTION NMR | Cite: | Solution structure of oxidized Saccharomyces cerevisiae iso-1-cytochrome c. Biochemistry, 36, 1997
|
|
7MTQ
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7mtq by Molmil](/molmil-images/mine/7mtq) | CryoEM Structure of Full-Length mGlu2 in Inactive-State Bound to Antagonist LY341495 | Descriptor: | 2-[(1S,2S)-2-carboxycyclopropyl]-3-(9H-xanthen-9-yl)-D-alanine, 2-acetamido-2-deoxy-beta-D-glucopyranose, Metabotropic glutamate receptor 2 | Authors: | Seven, A.B, Barros-Alvarez, X, Skiniotis, G. | Deposit date: | 2021-05-13 | Release date: | 2021-07-07 | Last modified: | 2021-07-28 | Method: | ELECTRON MICROSCOPY (3.65 Å) | Cite: | G-protein activation by a metabotropic glutamate receptor. Nature, 595, 2021
|
|
7MTR
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7mtr by Molmil](/molmil-images/mine/7mtr) | CryoEM Structure of Full-Length mGlu2 Bound to Ago-PAM ADX55164 and Glutamate | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-methoxy-6-propyl-N-(2-{4-[(1H-tetrazol-5-yl)methoxy]phenyl}ethyl)thieno[2,3-d]pyrimidin-4-amine, GLUTAMIC ACID, ... | Authors: | Seven, A.B, Barros-Alvarez, X, Skiniotis, G. | Deposit date: | 2021-05-13 | Release date: | 2021-07-07 | Last modified: | 2021-09-08 | Method: | ELECTRON MICROSCOPY (3.3 Å) | Cite: | G-protein activation by a metabotropic glutamate receptor. Nature, 595, 2021
|
|
7MTS
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7mts by Molmil](/molmil-images/mine/7mts) | CryoEM Structure of mGlu2 - Gi Complex | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-methoxy-6-propyl-N-(2-{4-[(1H-tetrazol-5-yl)methoxy]phenyl}ethyl)thieno[2,3-d]pyrimidin-4-amine, GLUTAMIC ACID, ... | Authors: | Seven, A.B, Barros-Alvarez, X, Skiniotis, G. | Deposit date: | 2021-05-13 | Release date: | 2021-07-07 | Last modified: | 2021-07-28 | Method: | ELECTRON MICROSCOPY (3.2 Å) | Cite: | G-protein activation by a metabotropic glutamate receptor. Nature, 595, 2021
|
|
6IVA
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6iva by Molmil](/molmil-images/mine/6iva) | |
7YAD
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7yad by Molmil](/molmil-images/mine/7yad) | Cryo-EM structure of S309-RBD-RBD-S309 in the S309-bound Omicron spike protein (local refinement) | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, S309 neutralizing antibody heavy chain, S309 neutralizing antibody light chain, ... | Authors: | Zhao, Z.N, Xie, Y.F, Qi, J.X, Gao, F. | Deposit date: | 2022-06-27 | Release date: | 2022-08-31 | Last modified: | 2022-09-07 | Method: | ELECTRON MICROSCOPY (2.66 Å) | Cite: | Omicron SARS-CoV-2 mutations stabilize spike up-RBD conformation and lead to a non-RBM-binding monoclonal antibody escape. Nat Commun, 13, 2022
|
|
3B9C
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3b9c by Molmil](/molmil-images/mine/3b9c) | Crystal Structure of Human GRP CRD | Descriptor: | BETA-MERCAPTOETHANOL, HSPC159, SULFATE ION | Authors: | Zhou, D, Ge, H.H, Niu, L.W, Teng, M.K. | Deposit date: | 2007-11-05 | Release date: | 2008-03-18 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Crystal structure of the C-terminal conserved domain of human GRP, a galectin-related protein, reveals a function mode different from those of galectins. Proteins, 71, 2008
|
|
3B4D
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3b4d by Molmil](/molmil-images/mine/3b4d) | Crystal Structure of Human PABPN1 RRM | Descriptor: | Polyadenylate-binding protein 2 | Authors: | Ge, H, Tong, S, Teng, M, Niu, L. | Deposit date: | 2007-10-24 | Release date: | 2008-01-15 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (2.001 Å) | Cite: | Crystal structure and possible dimerization of the single RRM of human PABPN1 Proteins, 71, 2008
|
|
3BS8
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3bs8 by Molmil](/molmil-images/mine/3bs8) | Crystal structure of Glutamate 1-Semialdehyde Aminotransferase complexed with pyridoxamine-5'-phosphate From Bacillus subtilis | Descriptor: | 4'-DEOXY-4'-AMINOPYRIDOXAL-5'-PHOSPHATE, Glutamate-1-semialdehyde 2,1-aminomutase | Authors: | Ge, H, Fan, J, Teng, M, Niu, L. | Deposit date: | 2007-12-22 | Release date: | 2008-12-23 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Crystal structure of Glutamate1-semialdehyde aminotransferase from Bacillus subtilis with bound pyridoxamine-5'-phosphate Biochem.Biophys.Res.Commun., 402, 2010
|
|
3B4M
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3b4m by Molmil](/molmil-images/mine/3b4m) | Crystal Structure of Human PABPN1 RRM | Descriptor: | Polyadenylate-binding protein 2 | Authors: | Ge, H, Zhou, D, Teng, M, Niu, L. | Deposit date: | 2007-10-24 | Release date: | 2008-01-15 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (2.82 Å) | Cite: | Crystal structure and possible dimerization of the single RRM of human PABPN1 Proteins, 71, 2008
|
|
6TKB
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6tkb by Molmil](/molmil-images/mine/6tkb) | ChiLob 7/4 H2 HC-C224S F(ab')2 | Descriptor: | Chilob 7/4 H2 heavy chain C224S, Chilob 7/4 H2 kappa chain | Authors: | Orr, C.M, Fisher, H, Tews, I. | Deposit date: | 2019-11-28 | Release date: | 2021-06-09 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Hinge disulfides in human IgG2 CD40 antibodies modulate receptor signaling by regulation of conformation and flexibility. Sci Immunol, 7, 2022
|
|
6TKE
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6tke by Molmil](/molmil-images/mine/6tke) | ChiLob 7/4 H2 HC-C224S Kappa LC-C214S F(ab')2 | Descriptor: | ChiLob 7/4 H2 heavy chain C224S, ChiLob 7/4 H2 kappa chain C214S | Authors: | Orr, C.M, Fisher, H, Tews, I. | Deposit date: | 2019-11-28 | Release date: | 2021-06-09 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (2.35 Å) | Cite: | Hinge disulfides in human IgG2 CD40 antibodies modulate receptor signaling by regulation of conformation and flexibility. Sci Immunol, 7, 2022
|
|
6TKF
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6tkf by Molmil](/molmil-images/mine/6tkf) | ChiLob 7/4 H2 HC-C225S KappaLC-C214S F(ab')2 | Descriptor: | ChiLob 7/4 H2 Heavy chain C225S, ChiLob 7/4 H2 Kappa light chain C214S | Authors: | Orr, C.M, Fisher, H, Tews, I. | Deposit date: | 2019-11-28 | Release date: | 2021-06-09 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (2.18 Å) | Cite: | Hinge disulfides in human IgG2 CD40 antibodies modulate receptor signaling by regulation of conformation and flexibility. Sci Immunol, 7, 2022
|
|
6TKC
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6tkc by Molmil](/molmil-images/mine/6tkc) | ChiLob 7/4 H2 HC-C225S F(ab')2 | Descriptor: | Chilob 7/4 H2 heavy chain C225S, Chilob 7/4 H2 kappa chain | Authors: | Orr, C.M, Fisher, H, Tews, I. | Deposit date: | 2019-11-28 | Release date: | 2021-06-09 | Last modified: | 2022-12-21 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Hinge disulfides in human IgG2 CD40 antibodies modulate receptor signaling by regulation of conformation and flexibility. Sci Immunol, 7, 2022
|
|
6TKD
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6tkd by Molmil](/molmil-images/mine/6tkd) | ChiLob 7/4 H2 HC-C228S F(ab')2 | Descriptor: | Chilob 7/4 H2 heavy chain C228S, Chilob 7/4 H2 kappa chain | Authors: | Orr, C.M, Fisher, H, Tews, I. | Deposit date: | 2019-11-28 | Release date: | 2021-06-09 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Hinge disulfides in human IgG2 CD40 antibodies modulate receptor signaling by regulation of conformation and flexibility. Sci Immunol, 7, 2022
|
|
6U9H
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6u9h by Molmil](/molmil-images/mine/6u9h) | Arabidopsis thaliana acetohydroxyacid synthase complex | Descriptor: | Acetolactate synthase small subunit 2, chloroplastic, Acetolactate synthase, ... | Authors: | Guddat, L.W, Low, Y.S, Rao, Z. | Deposit date: | 2019-09-08 | Release date: | 2020-07-15 | Last modified: | 2024-03-20 | Method: | ELECTRON MICROSCOPY (3.8 Å) | Cite: | Structures of fungal and plant acetohydroxyacid synthases. Nature, 586, 2020
|
|
6U9D
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6u9d by Molmil](/molmil-images/mine/6u9d) | |
6VZ8
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6vz8 by Molmil](/molmil-images/mine/6vz8) | |
2HDZ
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2hdz by Molmil](/molmil-images/mine/2hdz) | Crystal Structure Analysis of the UBF HMG box5 | Descriptor: | Nucleolar transcription factor 1 | Authors: | Rong, H, Teng, M.K, Niu, L.W. | Deposit date: | 2006-06-21 | Release date: | 2007-06-26 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Structure of human upstream binding factor HMG box 5 and site for binding of the cell-cycle regulatory factor TAF1 Acta Crystallogr.,Sect.D, 63, 2007
|
|
4LUQ
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4luq by Molmil](/molmil-images/mine/4luq) | |