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8UPB
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BU of 8upb by Molmil
De novo designed IL-6 mimetic
Descriptor: De novo designed IL-6 mimetic
Authors:Borowska, M.T, Jude, K.M, Garcia, K.C.
Deposit date:2023-10-22
Release date:2024-08-28
Method:X-RAY DIFFRACTION (1.48 Å)
Cite:De novo design of miniprotein antagonists of cytokine storm inducers.
Nat Commun, 15, 2024
8HW1
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BU of 8hw1 by Molmil
Far-red light-harvesting complex of Antarctic alga Prasiola crispa
Descriptor: (1S)-4-[(1E,3Z,5E,7E,9E,11E,13E,15E,17E)-3-(hydroxymethyl)-7,12,16-trimethyl-18-[(1R,4S)-2,6,6-trimethyl-4-oxidanyl-cyclohex-2-en-1-yl]octadeca-1,3,5,7,9,11,13,15,17-nonaenyl]-3,5,5-trimethyl-cyclohex-3-en-1-ol, (3S,5R,6S,3'S,5'R,6'S)-5,6,5',6'-DIEPOXY-5,6,5',6'- TETRAHYDRO-BETA,BETA-CAROTENE-3,3'-DIOL, CHLOROPHYLL A, ...
Authors:Kosugi, M, Kawasaki, M, Shibata, Y, Moriya, T, Adachi, N, Senda, T.
Deposit date:2022-12-28
Release date:2023-01-18
Last modified:2024-07-03
Method:ELECTRON MICROSCOPY (3.13 Å)
Cite:Uphill energy transfer mechanism for photosynthesis in an Antarctic alga.
Nat Commun, 14, 2023
6O3A
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BU of 6o3a by Molmil
Crystal structure of Frizzled 7 CRD in complex with F7.B Fab
Descriptor: 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, 3-CYCLOHEXYL-1-PROPYLSULFONIC ACID, ...
Authors:Raman, S, Beilschmidt, M, Fransson, J, Julien, J.P.
Deposit date:2019-02-26
Release date:2019-04-03
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structure-guided design fine-tunes pharmacokinetics, tolerability, and antitumor profile of multispecific frizzled antibodies.
Proc. Natl. Acad. Sci. U.S.A., 116, 2019
6O3B
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BU of 6o3b by Molmil
Crystal structure of Frizzled 7 CRD in complex with F6 Fab
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Antibody Fab F6, Heavy chain, ...
Authors:Raman, S, Beilschmidt, M, Fransson, J, Julien, J.P.
Deposit date:2019-02-26
Release date:2019-04-03
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structure-guided design fine-tunes pharmacokinetics, tolerability, and antitumor profile of multispecific frizzled antibodies.
Proc. Natl. Acad. Sci. U.S.A., 116, 2019
6O39
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BU of 6o39 by Molmil
Crystal structure of Frizzled 5 CRD in complex with F2.I Fab
Descriptor: 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, ACETATE ION, ...
Authors:Raman, S, Beilschmidt, M, Fransson, J, Julien, J.P.
Deposit date:2019-02-26
Release date:2019-04-03
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structure-guided design fine-tunes pharmacokinetics, tolerability, and antitumor profile of multispecific frizzled antibodies.
Proc. Natl. Acad. Sci. U.S.A., 116, 2019
5XIW
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BU of 5xiw by Molmil
Crystal structure of T2R-TTL-Colchicine complex
Descriptor: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CALCIUM ION, GLYCEROL, ...
Authors:Wang, Y, Yang, J, Wang, T, Chen, L.
Deposit date:2017-04-27
Release date:2018-04-18
Last modified:2024-03-27
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:The compound millepachine and its derivatives inhibit tubulin polymerization by irreversibly binding to the colchicine-binding site in beta-tubulin.
J. Biol. Chem., 2018
5XP3
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BU of 5xp3 by Molmil
Crystal structure of apo T2R-TTL
Descriptor: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CALCIUM ION, GLYCEROL, ...
Authors:Wang, Y, Yang, J, Wang, T, Chen, L.
Deposit date:2017-05-31
Release date:2017-10-25
Last modified:2024-03-27
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:The compound millepachine and its derivatives inhibit tubulin polymerization by irreversibly binding to the colchicine-binding site in beta-tubulin.
J. Biol. Chem., 2018
5YL2
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BU of 5yl2 by Molmil
Crystal structure of T2R-TTL-Y28 complex
Descriptor: (E)-1-(5-methoxy-2,2-dimethyl-chromen-8-yl)-3-(4-methoxy-3-oxidanyl-phenyl)prop-2-en-1-one, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CALCIUM ION, ...
Authors:Yang, J.H, Yang, T, Wen, J.L, Chen, L.J.
Deposit date:2017-10-16
Release date:2018-04-18
Last modified:2024-03-27
Method:X-RAY DIFFRACTION (2.09 Å)
Cite:The compound millepachine and its derivatives inhibit tubulin polymerization by irreversibly binding to the colchicine-binding site in beta-tubulin.
J. Biol. Chem., 2018
6J04
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BU of 6j04 by Molmil
Crystal structure of full length human LC3B delta G120 mutant (2_125)
Descriptor: Microtubule-associated proteins 1A/1B light chain 3B, SULFATE ION
Authors:Ding, Y, Lu, B.X, Wang, Z.Y.
Deposit date:2018-12-21
Release date:2019-11-06
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (1.899 Å)
Cite:Allele-selective lowering of mutant HTT protein by HTT-LC3 linker compounds
Nature, 575, 2019
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