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8CG6
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BU of 8cg6 by Molmil
The ACP crosslinked to the SAT of the cercosporin fungal non-reducing polyketide synthase (NR-PKS) CTB1 (ACP:SAT-KS-MAT)
Descriptor: Acyl carrier protein (ACP) of Non-reducing polyketide synthase CTB1, Non-reducing polyketide synthase CTB1, N~3~-[(2R)-2-hydroxy-3,3-dimethyl-4-(phosphonooxy)butanoyl]-N-[2-(propanoylamino)ethyl]-beta-alaninamide
Authors:Munoz-Hernandez, H, Tittes, Y.U, Maier, T.
Deposit date:2023-02-03
Release date:2024-02-21
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:CryoEM structure of ACP crosslinked to SAT of the cercosporin fungal non-reducing polyketide synthase (NR-PKS) CTB1 (ACP:SAT-KS-MAT) at 3.4 Angstroms resolution
To Be Published
8CPQ
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BU of 8cpq by Molmil
Crystal structure of human protein disulfide isomerase PDIA6 domain b
Descriptor: Protein disulfide-isomerase A6
Authors:Jakob, R.P, Leder, A.L, Hiller, S, Maier, T.
Deposit date:2023-03-03
Release date:2024-03-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Crystal structure of human protein disulfide isomerase PDIA6 domain b
To Be Published
6YL3
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BU of 6yl3 by Molmil
High resolution cryo-EM structure of urease from the pathogen Yersinia enterocolitica
Descriptor: NICKEL (II) ION, Urease subunit alpha, Urease subunit beta, ...
Authors:Righetto, R.D, Anton, L, Adaixo, R, Jakob, R, Zivanov, J, Mahi, M.A, Ringler, P, Schwede, T, Maier, T, Stahlberg, H.
Deposit date:2020-04-06
Release date:2020-05-06
Last modified:2020-10-21
Method:ELECTRON MICROSCOPY (1.98 Å)
Cite:High-resolution cryo-EM structure of urease from the pathogen Yersinia enterocolitica.
Nat Commun, 11, 2020
3MF2
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BU of 3mf2 by Molmil
Crystal structure of class II aaRS homologue (Bll0957) complexed with AMP
Descriptor: ADENOSINE MONOPHOSPHATE, Bll0957 protein, GLYCEROL, ...
Authors:Weygand-Durasevic, I, Mocibob, M, Ivic, N, Bilokapic, S, Maier, T, Luic, M, Ban, N.
Deposit date:2010-04-01
Release date:2010-07-28
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:Homologs of aminoacyl-tRNA synthetases acylate carrier proteins and provide a link between ribosomal and nonribosomal peptide synthesis
Proc.Natl.Acad.Sci.USA, 107, 2010
3MEY
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BU of 3mey by Molmil
Crystal structure of class II aaRS homologue (Bll0957) complexed with ATP
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, Bll0957 protein, MAGNESIUM ION, ...
Authors:Weygand-Durasevic, I, Mocibob, M, Ivic, N, Bilokapic, S, Maier, T, Luic, M, Ban, N.
Deposit date:2010-04-01
Release date:2010-07-28
Last modified:2017-11-08
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Homologs of aminoacyl-tRNA synthetases acylate carrier proteins and provide a link between ribosomal and nonribosomal peptide synthesis
Proc.Natl.Acad.Sci.USA, 107, 2010
3MF1
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BU of 3mf1 by Molmil
Crystal structure of class II aaRS homologue (Bll0957) complexed with an analogue of glycyl adenylate
Descriptor: 5'-O-(glycylsulfamoyl)adenosine, Bll0957 protein, ZINC ION
Authors:Weygand-Durasevic, I, Mocibob, M, Ivic, N, Bilokapic, S, Maier, T, Luic, M, Ban, N.
Deposit date:2010-04-01
Release date:2010-07-28
Last modified:2017-11-08
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Homologs of aminoacyl-tRNA synthetases acylate carrier proteins and provide a link between ribosomal and nonribosomal peptide synthesis
Proc.Natl.Acad.Sci.USA, 107, 2010
4XOD
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BU of 4xod by Molmil
Crystal structure of a FimH*DsG complex from E.coli F18
Descriptor: FimG protein, FimH protein
Authors:Jakob, R.P, Sauer, M.M, Glockshuber, R, Maier, T.
Deposit date:2015-01-16
Release date:2016-01-27
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (1.14 Å)
Cite:Catch-bond mechanism of the bacterial adhesin FimH.
Nat Commun, 7, 2016
4XOC
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BU of 4xoc by Molmil
Crystal structure of the FimH lectin domain from E.coli F18 in complex with heptyl alpha-D-mannopyrannoside
Descriptor: FimH protein, heptyl alpha-D-mannopyranoside
Authors:Jakob, R.P, Sauer, M.M, Navarra, G, Ernst, B, Glockshuber, R, Maier, T.
Deposit date:2015-01-16
Release date:2016-01-27
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (1.42 Å)
Cite:Catch-bond mechanism of the bacterial adhesin FimH.
Nat Commun, 7, 2016
4XOB
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BU of 4xob by Molmil
Crystal structure of a FimH*DsF complex from E.coli K12 with bound heptyl alpha-D-mannopyrannoside
Descriptor: FimF, Protein FimH, SULFATE ION, ...
Authors:Jakob, R.P, Eras, J, Navarra, G, Ernst, B, Glockshuber, R, Maier, T.
Deposit date:2015-01-16
Release date:2016-01-27
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (3.003 Å)
Cite:Catch-bond mechanism of the bacterial adhesin FimH.
Nat Commun, 7, 2016
4XOA
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BU of 4xoa by Molmil
Crystal structure of a FimH*DsG complex from E.coli K12 in space group P1
Descriptor: FimG, Protein FimH
Authors:Jakob, R.P, Eras, J, Glockshuber, R, Maier, T.
Deposit date:2015-01-16
Release date:2016-01-27
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.541 Å)
Cite:Catch-bond mechanism of the bacterial adhesin FimH.
Nat Commun, 7, 2016
4XOE
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BU of 4xoe by Molmil
Crystal structure of a FimH*DsG complex from E.coli F18 with bound heptyl alpha-D-mannopyrannoside
Descriptor: CACODYLATE ION, FimG protein, FimH protein, ...
Authors:Jakob, R.P, Sauer, M.M, Navarra, G, Ernst, B, Glockshuber, R, Maier, T.
Deposit date:2015-01-16
Release date:2016-01-27
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Catch-bond mechanism of the bacterial adhesin FimH.
Nat Commun, 7, 2016
6SWR
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BU of 6swr by Molmil
Crystal structure of the lysosomal potassium channel MtTMEM175 T38A mutant soaked with zinc
Descriptor: DODECYL-BETA-D-MALTOSIDE, Nanobody, Maltose/maltodextrin-binding periplasmic protein,Maltodextrin-binding protein,Maltose/maltodextrin-binding periplasmic protein, ...
Authors:Brunner, J.D, Jakob, R.P, Schulze, T, Neldner, Y, Moroni, A, Thiel, G, Maier, T, Schenck, S.
Deposit date:2019-09-23
Release date:2020-04-15
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Structural basis for ion selectivity in TMEM175 K + channels.
Elife, 9, 2020
1W2B
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BU of 1w2b by Molmil
Trigger Factor ribosome binding domain in complex with 50S
Descriptor: 23S RRNA, 50S RIBOSOMAL PROTEIN L10E, 50S RIBOSOMAL PROTEIN L13P, ...
Authors:Ferbitz, L, Maier, T, Patzelt, H, Bukau, B, Deuerling, E, Ban, N.
Deposit date:2004-07-01
Release date:2004-09-02
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (3.5 Å)
Cite:Trigger Factor in Complex with the Ribosome Forms a Molecular Cradle for Nascent Proteins
Nature, 431, 2004
7R03
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BU of 7r03 by Molmil
Neurofibromin occluded conformation
Descriptor: Isoform I of Neurofibromin
Authors:Chaker-Margot, M, Scheffzek, K, Maier, T.
Deposit date:2022-02-01
Release date:2022-03-30
Last modified:2024-07-17
Method:ELECTRON MICROSCOPY (3.6 Å)
Cite:Structural basis of activation of the tumor suppressor protein neurofibromin.
Mol.Cell, 82, 2022
7R04
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BU of 7r04 by Molmil
Neurofibromin in open conformation
Descriptor: 5'-GUANOSINE-DIPHOSPHATE-MONOTHIOPHOSPHATE, Isoform I of Neurofibromin
Authors:Chaker-Margot, M, Scheffzek, K, Maier, T.
Deposit date:2022-02-01
Release date:2022-03-30
Last modified:2024-07-17
Method:ELECTRON MICROSCOPY (3.7 Å)
Cite:Structural basis of activation of the tumor suppressor protein neurofibromin.
Mol.Cell, 82, 2022
5MUC
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BU of 5muc by Molmil
Crystal structure of the FimH lectin domain in complex with 1,5-Anhydromannitol
Descriptor: 1-deoxy-alpha-D-mannopyranose, Protein FimH
Authors:Jakob, R.P, Rabbani, S, Ernst, B, Maier, T.
Deposit date:2017-01-13
Release date:2018-02-14
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:KinITC-One Method Supports both Thermodynamic and Kinetic SARs as Exemplified on FimH Antagonists.
Chemistry, 24, 2018
8RQH
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BU of 8rqh by Molmil
Crystal Structure of the flavoprotein monooxygenase TrlE from Streptomyces cyaneofuscatus Soc7
Descriptor: CHLORIDE ION, FLAVIN-ADENINE DINUCLEOTIDE, SULFATE ION, ...
Authors:Sowa, S.T, Hoeing, L.S, Jakob, R.P, Maier, T, Teufel, R.
Deposit date:2024-01-18
Release date:2024-05-15
Last modified:2024-06-05
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Biosynthesis of the bacterial antibiotic 3,7-dihydroxytropolone through enzymatic salvaging of catabolic shunt products.
Chem Sci, 15, 2024
7R1V
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BU of 7r1v by Molmil
Crystal structure of E.coli BamA beta-barrel in complex with dynobactin A
Descriptor: Dynobactin A, Outer membrane protein assembly factor BamA
Authors:Jakob, R.P, Hiller, S, Maier, T.
Deposit date:2022-02-03
Release date:2022-09-28
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Computational identification of a systemic antibiotic for gram-negative bacteria.
Nat Microbiol, 7, 2022
7R1W
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BU of 7r1w by Molmil
E. coli BAM complex (BamABCDE) bound to dynobactin A
Descriptor: Dynobactin A, Outer membrane protein assembly factor BamA, Outer membrane protein assembly factor BamB, ...
Authors:Jakob, R.P, Hiller, S, Maier, T.
Deposit date:2022-02-03
Release date:2022-09-28
Last modified:2024-04-03
Method:ELECTRON MICROSCOPY (3.6 Å)
Cite:Computational identification of a systemic antibiotic for gram-negative bacteria.
Nat Microbiol, 7, 2022
6QGY
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BU of 6qgy by Molmil
Crystal structure of E.coli BamA beta-barrel in complex with nanobody B12
Descriptor: (HYDROXYETHYLOXY)TRI(ETHYLOXY)OCTANE, NanoB12, Outer membrane protein assembly factor BamA
Authors:Hartmann, J.-B, Kaur, H, Jakob, R.P, Zahn, M, Zimmermann, I, Seeger, M, Maier, T, Hiller, S.
Deposit date:2019-01-14
Release date:2019-06-26
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (2.509 Å)
Cite:Identification of conformation-selective nanobodies against the membrane protein insertase BamA by an integrated structural biology approach.
J.Biomol.Nmr, 73, 2019
6QGW
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BU of 6qgw by Molmil
Crystal structure of E.coli BamA beta-barrel in complex with nanobody E6
Descriptor: (HYDROXYETHYLOXY)TRI(ETHYLOXY)OCTANE, NanoE6, Outer membrane protein assembly factor BamA
Authors:Hartmann, J.-B, Kaur, H, Jakob, R.P, Zahn, M, Zimmermann, I, Seeger, M, Maier, T, Hiller, S.
Deposit date:2019-01-14
Release date:2019-06-26
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (1.938 Å)
Cite:Identification of conformation-selective nanobodies against the membrane protein insertase BamA by an integrated structural biology approach.
J.Biomol.Nmr, 73, 2019
6QGX
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BU of 6qgx by Molmil
Crystal structure of E.coli BamA beta-barrel in complex with nanobody F7
Descriptor: (HYDROXYETHYLOXY)TRI(ETHYLOXY)OCTANE, NanoF7, Outer membrane protein assembly factor BamA
Authors:Hartmann, J.-B, Kaur, H, Jakob, R.P, Zahn, M, Zimmermann, I, Seeger, M, Maier, T, Hiller, S.
Deposit date:2019-01-14
Release date:2019-06-26
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Identification of conformation-selective nanobodies against the membrane protein insertase BamA by an integrated structural biology approach.
J.Biomol.Nmr, 73, 2019
1W26
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BU of 1w26 by Molmil
Trigger Factor in Complex with the Ribosome forms a Molecular Cradle for Nascent Proteins
Descriptor: TRIGGER FACTOR
Authors:Ferbitz, L, Maier, T, Patzelt, H, Bukau, B, Deuerling, E, Ban, N.
Deposit date:2004-06-28
Release date:2004-09-02
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Trigger Factor in Complex with the Ribosome Forms a Molecular Cradle for Nascent Proteins
Nature, 431, 2004
9F42
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BU of 9f42 by Molmil
cryo-EM structure of LST2 TOS peptide bound to human mTOR complex 1, focused on RAPTOR
Descriptor: Lateral signaling target protein 2 homolog, Regulatory-associated protein of mTOR
Authors:Craigie, L.M, Maier, T.
Deposit date:2024-04-26
Release date:2024-08-14
Last modified:2024-08-28
Method:ELECTRON MICROSCOPY (3.27 Å)
Cite:mTORC1 phosphorylates and stabilizes LST2 to negatively regulate EGFR.
Proc.Natl.Acad.Sci.USA, 121, 2024
9F43
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BU of 9f43 by Molmil
cryo-EM structure of human LST2 bound to human mTOR complex 1, focused on RAPTOR
Descriptor: Lateral signaling target protein 2 homolog, Regulatory-associated protein of mTOR
Authors:Craigie, L.M, Maier, T.
Deposit date:2024-04-26
Release date:2024-08-14
Last modified:2024-08-28
Method:ELECTRON MICROSCOPY (3.49 Å)
Cite:mTORC1 phosphorylates and stabilizes LST2 to negatively regulate EGFR.
Proc.Natl.Acad.Sci.USA, 121, 2024

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数据于2024-09-18公开中

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