9F42
cryo-EM structure of LST2 TOS peptide bound to human mTOR complex 1, focused on RAPTOR
Summary for 9F42
Entry DOI | 10.2210/pdb9f42/pdb |
EMDB information | 50181 |
Descriptor | Regulatory-associated protein of mTOR, Lateral signaling target protein 2 homolog (2 entities in total) |
Functional Keywords | mtor, mtorc1, lst2, zfyve28, egfr, tos, signaling protein |
Biological source | Homo sapiens (human) More |
Total number of polymer chains | 2 |
Total formula weight | 154425.39 |
Authors | |
Primary citation | Battaglioni, S.,Craigie, L.M.,Filippini, S.,Maier, T.,Hall, M.N. mTORC1 phosphorylates and stabilizes LST2 to negatively regulate EGFR Proc.Natl.Acad.Sci.USA, 2024 |
Experimental method |
Structure validation
No wwPDB Validation report is currently available for this entry.