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9F42

cryo-EM structure of LST2 TOS peptide bound to human mTOR complex 1, focused on RAPTOR

Summary for 9F42
Entry DOI10.2210/pdb9f42/pdb
EMDB information50181
DescriptorRegulatory-associated protein of mTOR, Lateral signaling target protein 2 homolog (2 entities in total)
Functional Keywordsmtor, mtorc1, lst2, zfyve28, egfr, tos, signaling protein
Biological sourceHomo sapiens (human)
More
Total number of polymer chains2
Total formula weight154425.39
Authors
Craigie, L.M.,Maier, T. (deposition date: 2024-04-26, release date: 2024-08-14)
Primary citationBattaglioni, S.,Craigie, L.M.,Filippini, S.,Maier, T.,Hall, M.N.
mTORC1 phosphorylates and stabilizes LST2 to negatively regulate EGFR
Proc.Natl.Acad.Sci.USA, 2024
Experimental method
Structure validation
No wwPDB Validation report is currently available for this entry.

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PDB entries from 2024-08-14

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