9F42

cryo-EM structure of LST2 TOS peptide bound to human mTOR complex 1, focused on RAPTOR

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (E)	Regulatory-associated protein of mTOR	polymer	1363	152764.7	1	UniProt (Q8N122) Pfam (PF14538) Pfam (PF02985) Pfam (PF00400)	Homo sapiens (human)	Raptor,p150 target of rapamycin (TOR)-scaffold protein
2	B (G)	Lateral signaling target protein 2 homolog	polymer	13	1660.7	1	UniProt (Q9HCC9)	Homo sapiens	hLst2,Zinc finger FYVE domain-containing protein 28

Sequence modifications

E: 1 - 1335 (UniProt: Q8N122)

PDB	External Database	Details
His -27	-	expression tag
His -26	-	expression tag
His -25	-	expression tag
His -24	-	expression tag
His -23	-	expression tag
His -22	-	expression tag
His -21	-	expression tag
His -20	-	expression tag
His -19	-	expression tag
His -18	-	expression tag
Glu -17	-	expression tag
Gln -16	-	expression tag
Lys -15	-	expression tag
Leu -14	-	expression tag
Ile -13	-	expression tag
Ser -12	-	expression tag
Glu -11	-	expression tag
Glu -10	-	expression tag
Asp -9	-	expression tag
Leu -8	-	expression tag
Asp -7	-	expression tag
Tyr -6	-	expression tag
Lys -5	-	expression tag
Asp -4	-	expression tag
Asp -3	-	expression tag
Asp -2	-	expression tag
Asp -1	-	expression tag
Lys 0	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	154425.4
All*	Total formula weight	154425.4

*Water molecules are not included.