2WXC
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![BU of 2wxc by Molmil](/molmil-images/mine/2wxc) | The folding mechanism of BBL: Plasticity of transition-state structure observed within an ultrafast folding protein family. | Descriptor: | DIHYDROLIPOYLTRANSSUCCINASE | Authors: | Neuweiler, H, Sharpe, T.D, Rutherford, T.J, Johnson, C.M, Allen, M.D, Ferguson, N, Fersht, A.R. | Deposit date: | 2009-11-06 | Release date: | 2009-11-17 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | The Folding Mechanism of Bbl: Plasticity of Transition-State Structure Observed within an Ultrafast Folding Protein Family. J.Mol.Biol., 390, 2009
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1W4H
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![BU of 1w4h by Molmil](/molmil-images/mine/1w4h) | Peripheral-subunit from mesophilic, thermophilic and hyperthermophilic bacteria fold by ultrafast, apparently two-state transitions | Descriptor: | DIHYDROLIPOYLLYSINE-RESIDUE ACETYLTRANSFERASE | Authors: | Ferguson, N, Sharpe, T.D, Schartau, P.J, Allen, M.D, Johnson, C.M, Fersht, A.R. | Deposit date: | 2004-07-23 | Release date: | 2005-07-20 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | Ultra-Fast Barrier-Limited Folding in the Peripheral Subunit-Binding Domain Family. J.Mol.Biol., 353, 2005
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1W4E
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![BU of 1w4e by Molmil](/molmil-images/mine/1w4e) | Peripheral-subunit binding domains from mesophilic, thermophilic, and hyperthermophilic bacteria fold by ultrafast, apparently two-state transitions | Descriptor: | DIHYDROLIPOYLLYSINE-RESIDUE ACETYLTRANSFERASE | Authors: | Ferguson, N, Sharpe, T.D, Schartau, P.J, Allen, M.D, Johnson, C.M, Sato, S, Fersht, A.R. | Deposit date: | 2004-07-23 | Release date: | 2005-07-20 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | Ultra-Fast Barrier-Limited Folding in the Peripheral Subunit-Binding Domain Family. J.Mol.Biol., 353, 2005
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1W4K
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![BU of 1w4k by Molmil](/molmil-images/mine/1w4k) | Peripheral-subunit binding domains from mesophilic, thermophilic, and hyperthermophilic bacteria fold by ultrafast, apparently two-state transitions | Descriptor: | PYRUVATE DEHYDROGENASE E2 | Authors: | Ferguson, N, Sharpe, T.D, Schartau, P.J, Allen, M.D, Johnson, C.M, Sato, S, Fersht, A.R. | Deposit date: | 2004-07-23 | Release date: | 2005-07-20 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | Ultra-Fast Barrier-Limited Folding in the Peripheral Subunit-Binding Domain Family. J.Mol.Biol., 353, 2005
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1W4I
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![BU of 1w4i by Molmil](/molmil-images/mine/1w4i) | Peripheral-subunit binding domains from mesophilic, thermophilic, and hyperthermophilic bacteria fold by ultrafast, apparently two-state transitions | Descriptor: | PYRUVATE DEHYDROGENASE E2 | Authors: | Ferguson, N, Sharpe, T.D, Schartau, P.J, Allen, M.D, Johnson, C.M, Sato, S, Fersht, A.R. | Deposit date: | 2004-07-23 | Release date: | 2005-07-20 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | Ultra-Fast Barrier-Limited Folding in the Peripheral Subunit-Binding Domain Family. J.Mol.Biol., 353, 2005
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2J2S
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![BU of 2j2s by Molmil](/molmil-images/mine/2j2s) | Solution structure of the nonmethyl-CpG-binding CXXC domain of the leukaemia-associated MLL histone methyltransferase | Descriptor: | ZINC FINGER PROTEIN HRX, ZINC ION | Authors: | Allen, M.D, Grummitt, C.G, Hilcenko, C, Young-Min, S, Tonkin, L.M, Johnson, C.M, Bycroft, M, Warren, A.J. | Deposit date: | 2006-08-17 | Release date: | 2006-08-21 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | Solution Structure of the Nonmethyl-Cpg-Binding Cxxc Domain of the Leukaemia-Associated Mll Histone Methyltransferase Embo J., 25, 2006
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6QJY
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![BU of 6qjy by Molmil](/molmil-images/mine/6qjy) | |
2Y3W
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![BU of 2y3w by Molmil](/molmil-images/mine/2y3w) | |
5IHB
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![BU of 5ihb by Molmil](/molmil-images/mine/5ihb) | Structure of the immune receptor CD33 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Myeloid cell surface antigen CD33 | Authors: | Dodd, R.B. | Deposit date: | 2016-02-29 | Release date: | 2017-03-29 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (2.24 Å) | Cite: | Structure of ligand bound CD33 receptor associated with Alzheimer's disease To Be Published
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5J0B
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![BU of 5j0b by Molmil](/molmil-images/mine/5j0b) | Structure of the immune receptor CD33 in complex with 6'-sialyllactose | Descriptor: | 2-(2-METHOXYETHOXY)ETHANOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, Myeloid cell surface antigen CD33, ... | Authors: | Dodd, R.B. | Deposit date: | 2016-03-28 | Release date: | 2017-04-05 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (2.48 Å) | Cite: | STRUCTURE OF LIGAND BOUND CD33 RECEPTOR ASSOCIATED WITH ALZHEIMER'S DISEASE To Be Published
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5J06
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![BU of 5j06 by Molmil](/molmil-images/mine/5j06) | Structure of the immune receptor CD33 in complex with 3'-sialyllactose | Descriptor: | 2-(2-METHOXYETHOXY)ETHANOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, Myeloid cell surface antigen CD33, ... | Authors: | Dodd, R.B. | Deposit date: | 2016-03-27 | Release date: | 2017-04-05 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (2.66 Å) | Cite: | STRUCTURE OF LIGAND BOUND CD33 RECEPTOR ASSOCIATED WITH ALZHEIMER'S DISEASE To Be Published
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5KC2
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![BU of 5kc2 by Molmil](/molmil-images/mine/5kc2) | Negative stain structure of Vps15/Vps34 complex | Descriptor: | Phosphatidylinositol 3-kinase VPS34, Serine/threonine-protein kinase VPS15 | Authors: | Kirsten, M.L, Zhang, L, Ohashi, Y, Perisic, O, Williams, R.L, Sachse, C. | Deposit date: | 2016-06-04 | Release date: | 2016-10-05 | Last modified: | 2024-05-15 | Method: | ELECTRON MICROSCOPY (28 Å) | Cite: | Characterization of Atg38 and NRBF2, a fifth subunit of the autophagic Vps34/PIK3C3 complex. Autophagy, 12, 2016
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6HXY
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![BU of 6hxy by Molmil](/molmil-images/mine/6hxy) | |
6HXV
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![BU of 6hxv by Molmil](/molmil-images/mine/6hxv) | |
6HXT
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![BU of 6hxt by Molmil](/molmil-images/mine/6hxt) | |
4WIP
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![BU of 4wip by Molmil](/molmil-images/mine/4wip) | DIX domain of human Dvl2 | Descriptor: | PENTAETHYLENE GLYCOL, Segment polarity protein dishevelled homolog DVL-2 | Authors: | Fiedler, M, Bienz, M, Madrzak, J, Chin, J.W. | Deposit date: | 2014-09-26 | Release date: | 2015-05-13 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (2.691 Å) | Cite: | Ubiquitination of the Dishevelled DIX domain blocks its head-to-tail polymerization. Nat Commun, 6, 2015
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4WZP
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![BU of 4wzp by Molmil](/molmil-images/mine/4wzp) | Ser65 phosphorylated ubiquitin, major conformation | Descriptor: | SULFATE ION, ubiquitin | Authors: | Wauer, T, Wagstaff, J, Freund, S.M.V, Komander, D. | Deposit date: | 2014-11-20 | Release date: | 2015-01-14 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Ubiquitin Ser65 phosphorylation affects ubiquitin structure, chain assembly and hydrolysis. Embo J., 34, 2015
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5LNP
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![BU of 5lnp by Molmil](/molmil-images/mine/5lnp) | |
5LPH
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![BU of 5lph by Molmil](/molmil-images/mine/5lph) | Structure of the TOG domain of human Cep104 | Descriptor: | Centrosomal protein of 104 kDa | Authors: | van Breugel, M. | Deposit date: | 2016-08-13 | Release date: | 2017-01-11 | Last modified: | 2017-09-13 | Method: | X-RAY DIFFRACTION (2.25 Å) | Cite: | The Ciliopathy-Associated Cep104 Protein Interacts with Tubulin and Nek1 Kinase. Structure, 25, 2017
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5LPI
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![BU of 5lpi by Molmil](/molmil-images/mine/5lpi) | |
6S6A
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![BU of 6s6a by Molmil](/molmil-images/mine/6s6a) | Crystal structure of RagA-Q66L/RagC-T90N GTPase heterodimer complex | Descriptor: | GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ... | Authors: | Anandapadamanaban, M, Masson, G.R, Perisic, O, Kaufman, J, Williams, R.L. | Deposit date: | 2019-07-02 | Release date: | 2019-10-16 | Last modified: | 2024-05-15 | Method: | X-RAY DIFFRACTION (2.63 Å) | Cite: | Architecture of human Rag GTPase heterodimers and their complex with mTORC1. Science, 366, 2019
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6SB2
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![BU of 6sb2 by Molmil](/molmil-images/mine/6sb2) | cryo-EM structure of mTORC1 bound to active RagA/C GTPases | Descriptor: | GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, Ras-related GTP-binding protein A, ... | Authors: | Anandapadamanaban, M, Berndt, A, Masson, G.R, Perisic, O, Williams, R.L. | Deposit date: | 2019-07-18 | Release date: | 2019-10-16 | Last modified: | 2024-05-22 | Method: | ELECTRON MICROSCOPY (6.2 Å) | Cite: | Architecture of human Rag GTPase heterodimers and their complex with mTORC1. Science, 366, 2019
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6SB0
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![BU of 6sb0 by Molmil](/molmil-images/mine/6sb0) | cryo-EM structure of mTORC1 bound to PRAS40-fused active RagA/C GTPases | Descriptor: | GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, Proline-rich AKT1 substrate 1, ... | Authors: | Anandapadamanaban, M, Berndt, A, Masson, G.R, Perisic, O, Williams, R.L. | Deposit date: | 2019-07-18 | Release date: | 2019-10-16 | Last modified: | 2024-05-22 | Method: | ELECTRON MICROSCOPY (5.5 Å) | Cite: | Architecture of human Rag GTPase heterodimers and their complex with mTORC1. Science, 366, 2019
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6S6D
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![BU of 6s6d by Molmil](/molmil-images/mine/6s6d) | Crystal structure of RagA-Q66L-GTP/RagC-S75N-GDP GTPase heterodimer complex | Descriptor: | GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ... | Authors: | Anandapadamanaban, M, Masson, G.R, Perisic, O, Kaufman, J, Williams, R.L. | Deposit date: | 2019-07-02 | Release date: | 2019-10-16 | Last modified: | 2024-05-15 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Architecture of human Rag GTPase heterodimers and their complex with mTORC1. Science, 366, 2019
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4BXP
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![BU of 4bxp by Molmil](/molmil-images/mine/4bxp) | |