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4YOZ
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BU of 4yoz by Molmil
p107 pocket domain in complex with HPV E7 peptide
Descriptor: HPV E7 peptide, Retinoblastoma-like protein 1,Retinoblastoma-like protein 1, SULFATE ION
Authors:Liban, T.J, Guiley, K.Z, Felthousen, J.G, Ramanan, P, Litovchick, L, Rubin, S.M.
Deposit date:2015-03-12
Release date:2015-06-24
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.245 Å)
Cite:Structural mechanisms of DREAM complex assembly and regulation.
Genes Dev., 29, 2015
4YOS
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BU of 4yos by Molmil
p107 pocket domain complexed with LIN52 peptide
Descriptor: 1,2-ETHANEDIOL, Protein lin-52 homolog, Retinoblastoma-like protein 1,Retinoblastoma-like protein 1, ...
Authors:Guiley, K.Z, Liban, T.J, Felthousen, J.G, Ramanan, P, Tripathi, S, Litovchick, L, Rubin, S.M.
Deposit date:2015-03-12
Release date:2015-05-27
Last modified:2019-12-04
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structural mechanisms of DREAM complex assembly and regulation.
Genes Dev., 29, 2015
5FD3
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BU of 5fd3 by Molmil
Structure of Lin54 tesmin domain bound to DNA
Descriptor: DNA (5'-D(*CP*AP*GP*TP*TP*TP*CP*AP*AP*AP*CP*TP*C)-3'), DNA (5'-D(*GP*AP*GP*TP*TP*TP*GP*AP*AP*AP*CP*T)-3'), Protein lin-54 homolog, ...
Authors:Marceau, A.H, Felthousen, J.G, Goetsch, P.D, Lee, H, Tripathi, S.M, Strome, S, Litovchick, L, Rubin, S.M.
Deposit date:2015-12-15
Release date:2016-08-03
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.42 Å)
Cite:Structural basis for LIN54 recognition of CHR elements in cell cycle-regulated promoters.
Nat Commun, 7, 2016
6H1Y
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BU of 6h1y by Molmil
CRYSTAL STRUCTURE OF A CHIMERIC VARIANT OF THIOREDOXIN FROM ESCHERICHIA COLI
Descriptor: Thioredoxin 1,Thioredoxin (TrxA-1),Thioredoxin 1
Authors:Ruggiero, A, Smaldone, G, Esposito, L, Balasco, N, Vitagliano, L.
Deposit date:2018-07-12
Release date:2019-02-06
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2.99 Å)
Cite:Loop size optimization induces a strong thermal stabilization of the thioredoxin fold.
Febs J., 286, 2019
3CTK
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BU of 3ctk by Molmil
Crystal structure of the type 1 RIP bouganin
Descriptor: rRNA N-glycosidase
Authors:Fermani, S, Tosi, G, Falini, G, Ripamonti, A, Farini, V, Bolognesi, A, Polito, L.
Deposit date:2008-04-14
Release date:2008-05-27
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structure/function studies on two type 1 ribosome inactivating proteins: Bouganin and lychnin.
J.Struct.Biol., 168, 2009
8SWK
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BU of 8swk by Molmil
Cryo-EM structure of NLRP3 closed hexamer
Descriptor: 1-[4-(2-oxidanylpropan-2-yl)furan-2-yl]sulfonyl-3-(1,2,3,5-tetrahydro-s-indacen-4-yl)urea, ADENOSINE-5'-TRIPHOSPHATE, NACHT, ...
Authors:Yu, X, Matico, R.E, Miller, R, Schoubroeck, B.V, Grauwen, K, Suarez, J, Pietrak, B, Haloi, N, Yin, Y, Tresadern, G.J, Perez-Benito, L, Lindahl, E, Bottelbergs, A, Oehlrich, D, Opdenbosch, N.V, Sharma, S.
Deposit date:2023-05-18
Release date:2024-02-14
Method:ELECTRON MICROSCOPY (4.32 Å)
Cite:Cryo-EM structures of NLRP3 reveal its self-activation mechanism
Nat Commun, 2024
8SXN
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BU of 8sxn by Molmil
Structure of NLRP3 and NEK7 complex
Descriptor: 1-[4-(2-oxidanylpropan-2-yl)furan-2-yl]sulfonyl-3-(1,2,3,5-tetrahydro-s-indacen-4-yl)urea, ADENOSINE-5'-TRIPHOSPHATE, NACHT, ...
Authors:Yu, X, Matico, R.E, Miller, R, Schoubroeck, B.V, Grauwen, K, Suarez, J, Pietrak, B, Haloi, N, Yin, Y, Tresadern, G.J, Perez-Benito, L, Lindahl, E, Bottelbergs, A, Oehlrich, D, Opdenbosch, N.V, Sharma, S.
Deposit date:2023-05-22
Release date:2024-02-14
Method:ELECTRON MICROSCOPY (4.04 Å)
Cite:Cryo-EM structures of NLRP3 reveal its self-activation mechanism
Nat Commun, 2024
8SWF
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BU of 8swf by Molmil
Cryo-EM structure of NLRP3 open octamer
Descriptor: NACHT, LRR and PYD domains-containing protein 3
Authors:Yu, X, Matico, R.E, Miller, R, Schoubroeck, B.V, Grauwen, K, Suarez, J, Pietrak, B, Haloi, N, Yin, Y, Tresadern, G.J, Perez-Benito, L, Lindahl, E, Bottelbergs, A, Oehlrich, D, Opdenbosch, N.V, Sharma, S.
Deposit date:2023-05-18
Release date:2024-02-14
Method:ELECTRON MICROSCOPY (3.39 Å)
Cite:Cryo-EM structures of NLRP3 reveal its self-activation mechanism
Nat Commun, 2024
4X1T
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BU of 4x1t by Molmil
The crystal structure of Arabidopsis thaliana galactolipid synthase MGD1 in complex with UDP
Descriptor: 1,2-ETHANEDIOL, Monogalactosyldiacylglycerol synthase 1, chloroplastic, ...
Authors:Rocha, J, Breton, C.
Deposit date:2014-11-25
Release date:2016-02-10
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:Structural insights and membrane binding properties of MGD1, the major galactolipid synthase in plants.
Plant J., 85, 2016
4WYI
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BU of 4wyi by Molmil
The crystal structure of Arabidopsis thaliana galactolipid synthase, MGD1 (apo-form)
Descriptor: Monogalactosyldiacylglycerol synthase 1, chloroplastic
Authors:Rocha, J, Breton, C.
Deposit date:2014-11-17
Release date:2016-02-17
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structural insights and membrane binding properties of MGD1, the major galactolipid synthase in plants.
Plant J., 85, 2016
2MYM
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BU of 2mym by Molmil
Cullin3 - BTB interface: a novel target for stapled peptides
Descriptor: Cullin-3
Authors:Russo, L, Palmieri, M, Malgieri, G.
Deposit date:2015-01-27
Release date:2015-04-22
Last modified:2023-11-15
Method:SOLUTION NMR
Cite:Cullin3 - BTB Interface: A Novel Target for Stapled Peptides.
Plos One, 10, 2015
2MYL
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BU of 2myl by Molmil
Cullin3 - BTB interface: a novel target for stapled peptides
Descriptor: Cullin-3
Authors:Russo, L, Palmieri, M, Malgieri, G.
Deposit date:2015-01-27
Release date:2015-04-22
Last modified:2023-11-15
Method:SOLUTION NMR
Cite:Cullin3 - BTB Interface: A Novel Target for Stapled Peptides.
Plos One, 10, 2015
8CHW
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BU of 8chw by Molmil
Crystal structure of human PURA (fragment Pro216-Lys280, PUR repeat III)
Descriptor: 1,2-ETHANEDIOL, CHLORIDE ION, Transcriptional activator protein Pur-alpha
Authors:Janowski, R, Niessing, D.
Deposit date:2023-02-08
Release date:2024-02-21
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:PURA syndrome-causing mutations impair PUR-domain integrity and affect P-body association.
Elife, 13, 2024
8CHT
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BU of 8cht by Molmil
Crystal structure of human PURA (fragment Glu57-Glu212, PUR repeat I and II)
Descriptor: 1,2-ETHANEDIOL, ACETATE ION, Transcriptional activator protein Pur-alpha
Authors:Janowski, R, Niessing, D.
Deposit date:2023-02-08
Release date:2024-02-21
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:PURA syndrome-causing mutations impair PUR-domain integrity and affect P-body association.
Elife, 13, 2024
8CHV
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BU of 8chv by Molmil
Crystal structure of human PURA (fragment Glu57-Glu212, PUR repeat I and II) R140P mutant
Descriptor: Transcriptional activator protein Pur-alpha
Authors:Janowski, R, Niessing, D.
Deposit date:2023-02-08
Release date:2024-02-21
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:PURA syndrome-causing mutations impair PUR-domain integrity and affect P-body association.
Elife, 13, 2024
8CHU
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BU of 8chu by Molmil
Crystal structure of human PURA repeat I-II K97E mutant
Descriptor: 1,2-ETHANEDIOL, MAGNESIUM ION, Transcriptional activator protein Pur-alpha
Authors:Janowski, R, Niessing, D.
Deposit date:2023-02-08
Release date:2024-02-21
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (2.45 Å)
Cite:PURA syndrome-causing mutations impair PUR-domain integrity and affect P-body association.
Elife, 13, 2024
4GS9
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BU of 4gs9 by Molmil
Crystal structure of the high affinity heterodimer of HIF2 alpha and ARNT C-terminal PAS domains in complex with an inactive benzoxadiazole antagonist
Descriptor: 3,6,9,12,15,18,21-HEPTAOXATRICOSANE-1,23-DIOL, Aryl hydrocarbon receptor nuclear translocator, Endothelial PAS domain-containing protein 1, ...
Authors:Scheuermann, T.H, Gardner, K.H.
Deposit date:2012-08-27
Release date:2013-04-03
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (1.72 Å)
Cite:Development of Inhibitors of the PAS-B Domain of the HIF-2 alpha Transcription Factor
J.Med.Chem., 56, 2013
1HWO
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BU of 1hwo by Molmil
EBULIN COMPLEXED WITH LACTOSE, TRIGONAL CRYSTAL FORM
Descriptor: EBULIN, beta-D-galactopyranose-(1-4)-alpha-D-glucopyranose, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose
Authors:Pascal, J.M, Day, P.J, Monzingo, A.F, Ernst, S.R, Robertus, J.D.
Deposit date:2001-01-09
Release date:2001-01-24
Last modified:2023-08-09
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:2.8-A crystal structure of a nontoxic type-II ribosome-inactivating protein, ebulin l.
Proteins, 43, 2001
1HWM
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BU of 1hwm by Molmil
EBULIN,ORTHORHOMBIC CRYSTAL FORM MODEL
Descriptor: EBULIN, alpha-D-mannopyranose-(1-3)-[beta-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, beta-D-galactopyranose
Authors:Pascal, J.M, Day, P.J, Monzingo, A.F, Ernst, S.R, Robertus, J.D.
Deposit date:2001-01-09
Release date:2001-01-24
Last modified:2023-08-09
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:2.8-A crystal structure of a nontoxic type-II ribosome-inactivating protein, ebulin l.
Proteins, 43, 2001
1HWN
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BU of 1hwn by Molmil
EBULIN COMPLEXED WITH GALACTOSE, TRIGONAL CRYSTAL FORM
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, EBULIN, beta-D-galactopyranose
Authors:Pascal, J.M, Day, P.J, Monzingo, A.F, Ernst, S.R, Robertus, J.D.
Deposit date:2001-01-09
Release date:2001-01-24
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:2.8-A crystal structure of a nontoxic type-II ribosome-inactivating protein, ebulin l.
Proteins, 43, 2001
1HWP
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BU of 1hwp by Molmil
EBULIN COMPLEXED WITH PTEROIC ACID, TRIGONAL CRYSTAL FORM
Descriptor: EBULIN, PTEROIC ACID, beta-D-galactopyranose-(1-4)-beta-D-glucopyranose, ...
Authors:Pascal, J.M, Day, P.J, Monzingo, A.F, Ernst, S.R, Robertus, J.D.
Deposit date:2001-01-09
Release date:2001-01-24
Last modified:2023-08-09
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:2.8-A crystal structure of a nontoxic type-II ribosome-inactivating protein, ebulin l.
Proteins, 43, 2001
6C48
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BU of 6c48 by Molmil
Crystal structure of B-Myb-LIN9-LIN52 complex
Descriptor: Myb-related protein B, Protein lin-52 homolog, Protein lin-9 homolog, ...
Authors:Guiley, K.Z, Tripathi, S.M, Rubin, S.M.
Deposit date:2018-01-11
Release date:2018-09-19
Last modified:2019-12-04
Method:X-RAY DIFFRACTION (2.32 Å)
Cite:Structural mechanism of Myb-MuvB assembly.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
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