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7D4L
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BU of 7d4l by Molmil
X-ray crystal Structure of E.coli Dihydrofolate Reductase complexed with folate and NADP+ at pH7.0
Descriptor: Dihydrofolate reductase, FOLIC ACID, MANGANESE (II) ION, ...
Authors:Wan, Q, Dealwis, C.
Deposit date:2020-09-24
Release date:2021-06-09
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Capturing the Catalytic Proton of Dihydrofolate Reductase: Implications for General Acid-Base Catalysis
Acs Catalysis, 11, 2021
7D3Z
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BU of 7d3z by Molmil
X-ray crystal Structure of E.coli Dihydrofolate Reductase complexed with folate and NADP+ at pH4.5
Descriptor: Dihydrofolate reductase, FOLIC ACID, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
Authors:Wan, Q, Dealwis, C.
Deposit date:2020-09-21
Release date:2021-06-09
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:Capturing the Catalytic Proton of Dihydrofolate Reductase: Implications for General Acid-Base Catalysis
Acs Catalysis, 11, 2021
7D4X
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BU of 7d4x by Molmil
X-ray crystal Structure of E.coli Dihydrofolate Reductase complexed with folate and NADP+ at pH7.0
Descriptor: Dihydrofolate reductase, FOLIC ACID, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
Authors:Wan, Q, Dealwis, C.
Deposit date:2020-09-24
Release date:2021-06-09
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (1.599 Å)
Cite:Capturing the Catalytic Proton of Dihydrofolate Reductase: Implications for General Acid-Base Catalysis
Acs Catalysis, 11, 2021
7D6G
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BU of 7d6g by Molmil
Neutron crystal Structure of E.coli Dihydrofolate Reductase complexed with folate and NADP+ at pH4.5
Descriptor: Dihydrofolate reductase, FOLIC ACID, MANGANESE (II) ION, ...
Authors:Wan, Q, Dealwis, C.
Deposit date:2020-09-30
Release date:2021-06-09
Last modified:2024-04-03
Method:NEUTRON DIFFRACTION (1.65 Å), X-RAY DIFFRACTION
Cite:Capturing the Catalytic Proton of Dihydrofolate Reductase: Implications for General Acid-Base Catalysis
Acs Catalysis, 11, 2021
4YG4
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BU of 4yg4 by Molmil
HipB-O1-O1* complex
Descriptor: Antitoxin HipB, DNA (28-MER), DNA (5'-D(*AP*TP*AP*TP*CP*CP*CP*CP*TP*TP*AP*AP*GP*GP*GP*GP*AP*TP*AP*A)-3')
Authors:Schumacher, M.A.
Deposit date:2015-02-25
Release date:2015-07-29
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (3.5 Å)
Cite:HipBA-promoter structures reveal the basis of heritable multidrug tolerance.
Nature, 524, 2015
4YG7
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BU of 4yg7 by Molmil
Structure of FL autorepression promoter complex
Descriptor: Antitoxin HipB, DNA (50-MER), Serine/threonine-protein kinase HipA
Authors:Schumacher, M.A.
Deposit date:2015-02-25
Release date:2015-07-29
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (3.77 Å)
Cite:HipBA-promoter structures reveal the basis of heritable multidrug tolerance.
Nature, 524, 2015
2GLK
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BU of 2glk by Molmil
High-resolution study of D-Xylose isomerase, 0.94A resolution.
Descriptor: GLYCEROL, MANGANESE (II) ION, Xylose isomerase
Authors:Katz, A.K, Carrell, H.L, Hanson, B.L, Harp, J.M, Glusker, J.P, Bunick, G.J.
Deposit date:2006-04-05
Release date:2006-05-16
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (0.94 Å)
Cite:Locating active-site hydrogen atoms in D-xylose isomerase: Time-of-flight neutron diffraction.
Proc.Natl.Acad.Sci.Usa, 103, 2006
2Q98
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BU of 2q98 by Molmil
X-ray structure of a prolactin antagonist
Descriptor: Prolactin
Authors:Broutin, I.J.L, Ducruix, A, Jomain, J.B, Goffin, V.
Deposit date:2007-06-12
Release date:2007-09-11
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Structural and thermodynamic bases for the design of pure prolactin receptor antagonists: X-ray structure of Del1-9-G129R-hPRL.
J.Biol.Chem., 282, 2007
2NTC
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BU of 2ntc by Molmil
Crystal Structure of sv40 large T antigen origin binding domain with DNA
Descriptor: 21-nt PEN element of the SV40 DNA origin, large T antigen
Authors:Bohm, A, Meinke, G, Bullock, P.A.
Deposit date:2006-11-07
Release date:2007-02-13
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:The Crystal Structure of the SV40 T-Antigen Origin Binding Domain in Complex with DNA
Plos Biol., 5, 2007
2OG8
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BU of 2og8 by Molmil
crystal structure of aminoquinazoline 36 bound to Lck
Descriptor: N-{2-[(N,N-DIETHYLGLYCYL)AMINO]-5-(TRIFLUOROMETHYL)PHENYL}-4-METHYL-3-[2-(METHYLAMINO)QUINAZOLIN-6-YL]BENZAMIDE, Proto-oncogene tyrosine-protein kinase LCK
Authors:Huang, X.
Deposit date:2007-01-05
Release date:2007-02-27
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Discovery of Aminoquinazolines as Potent, Orally Bioavailable Inhibitors of Lck: Synthesis, SAR, and in Vivo Anti-Inflammatory Activity
J.Med.Chem., 49, 2006
3BKI
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BU of 3bki by Molmil
Crystal Structure of the GluR2 ligand binding core (S1S2J) in complex with FQX at 1.87 Angstroms
Descriptor: Glutamate receptor 2, [1,2,5]oxadiazolo[3,4-g]quinoxaline-6,7(5H,8H)-dione 1-oxide
Authors:Cruz, L, Estebanez-Perpina, E, Pfaff, S, Borngraeber, S, Bao, N, Fletterick, R, England, P.
Deposit date:2007-12-06
Release date:2008-09-16
Last modified:2019-09-04
Method:X-RAY DIFFRACTION (1.87 Å)
Cite:6-Azido-7-nitro-1,4-dihydroquinoxaline-2,3-dione (ANQX) forms an irreversible bond to the active site of the GluR2 AMPA receptor.
J.Med.Chem., 51, 2008
1OVD
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BU of 1ovd by Molmil
THE K136E MUTANT OF LACTOCOCCUS LACTIS DIHYDROOROTATE DEHYDROGENASE A IN COMPLEX WITH OROTATE
Descriptor: DIHYDROOROTATE DEHYDROGENASE A, FLAVIN MONONUCLEOTIDE, GLYCEROL, ...
Authors:Norager, S, Arent, S, Bjornberg, O, Ottosen, M, Lo Leggio, L, Jensen, K.F, Larsen, S.
Deposit date:2003-03-26
Release date:2003-08-19
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:Lactococcus lactis dihydroorotate dehydrogenase A mutants reveal important facets of the enzymatic function.
J.Biol.Chem., 278, 2003
2GUB
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BU of 2gub by Molmil
Crystal Structure of Metal Free D-Xylose Isomerase.
Descriptor: Xylose isomerase
Authors:Carrell, H.L, Katz, A.K, Glusker, J.P.
Deposit date:2006-04-29
Release date:2006-05-16
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Locating active-site hydrogen atoms in D-xylose isomerase: Time-of-flight neutron diffraction.
Proc.Natl.Acad.Sci.Usa, 103, 2006
7ZH7
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BU of 7zh7 by Molmil
Cryo-EM structure of ex vivo AA amyloid from renal tissue of a short hair cat deceased in a shelter
Descriptor: Serum amyloid A protein
Authors:Schulte, T, Chaves-Sanjuan, A, Ricagno, S.
Deposit date:2022-04-05
Release date:2022-11-30
Last modified:2024-07-24
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:Cryo-EM structure of ex vivo fibrils associated with extreme AA amyloidosis prevalence in a cat shelter.
Nat Commun, 13, 2022
5EBJ
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BU of 5ebj by Molmil
Joint X-ray/neutron structure of reversibly photoswitching chromogenic protein, Dathail
Descriptor: photoswitching chromogenic protein
Authors:Kovalevsky, A.Y, Langan, P.S, Bradbury, A.R.M.
Deposit date:2015-10-19
Release date:2016-04-06
Last modified:2023-11-15
Method:NEUTRON DIFFRACTION (2.5 Å), X-RAY DIFFRACTION
Cite:Evolution and characterization of a new reversibly photoswitching chromogenic protein, Dathail.
J.Mol.Biol., 428, 2016
6TH0
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BU of 6th0 by Molmil
Crystal structure of Arabidopsis thaliana NAA60 in complex with acetyl-CoA
Descriptor: ACETYL COENZYME *A, Acyl-CoA N-acyltransferases (NAT) superfamily protein
Authors:Layer, D, Kopp, J, Lapouge, K, Sinning, I.
Deposit date:2019-11-18
Release date:2020-06-24
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:The Arabidopsis N alpha -acetyltransferase NAA60 locates to the plasma membrane and is vital for the high salt stress response.
New Phytol., 228, 2020
6TI2
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BU of 6ti2 by Molmil
Structure of the Ustilago maydis chorismate mutase 1 in complex with KWL1-b from Zea mays
Descriptor: Chromosome 16, whole genome shotgun sequence, Ripening-related protein 3
Authors:Altegoer, F, Bange, G.
Deposit date:2019-11-21
Release date:2020-05-06
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (2.75 Å)
Cite:The two paralogous kiwellin proteins KWL1 and KWL1-b from maize are structurally related and have overlapping functions in plant defense.
J.Biol.Chem., 295, 2020
6TOU
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BU of 6tou by Molmil
Rabies virus glycoprotein PH domain in complex with the scFv fragment of broadly neutralizing human antibody RVC20
Descriptor: CALCIUM ION, CHLORIDE ION, Glycoprotein,Glycoprotein, ...
Authors:Hellert, J, Rey, F.A.
Deposit date:2019-12-12
Release date:2020-02-12
Last modified:2024-05-01
Method:X-RAY DIFFRACTION (2.587 Å)
Cite:Structure of the prefusion-locking broadly neutralizing antibody RVC20 bound to the rabies virus glycoprotein.
Nat Commun, 11, 2020
4Q11
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BU of 4q11 by Molmil
Crystal structure of Proteus mirabilis transcriptional regulator protein Crl at 1.95A resolution
Descriptor: 2-[N-CYCLOHEXYLAMINO]ETHANE SULFONIC ACID, Sigma factor-binding protein Crl
Authors:Norel, F, Mayer, C, Saul, F.A, Haouz, A.
Deposit date:2014-04-02
Release date:2014-08-06
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Structural and functional features of Crl proteins and identification of conserved surface residues required for interaction with the RpoS/ sigma S subunit of RNA polymerase.
Biochem.J., 463, 2014
6RX1
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BU of 6rx1 by Molmil
Crystal structure of human syncytin 1 in post-fusion conformation
Descriptor: CHLORIDE ION, GLYCEROL, Syncytin-1
Authors:Ruigrok, K, Backovic, M, Vaney, M.C, Rey, F.A.
Deposit date:2019-06-07
Release date:2019-11-20
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:X-ray Structures of the Post-fusion 6-Helix Bundle of the Human Syncytins and their Functional Implications.
J.Mol.Biol., 431, 2019
1ZY3
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BU of 1zy3 by Molmil
Structural model of complex of Bcl-w protein with Bid BH3-peptide
Descriptor: Apoptosis regulator Bcl-W, BH3-peptide from BH3 interacting domain death agonist protein
Authors:Denisov, A.Y, Gehring, K.
Deposit date:2005-06-09
Release date:2006-02-14
Last modified:2024-05-22
Method:SOLUTION NMR
Cite:Structural Model of the BCL-w-BID Peptide Complex and Its Interactions with Phospholipid Micelles.
Biochemistry, 45, 2006
6SCP
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BU of 6scp by Molmil
Cell Division Protein SepF in complex with C-terminal domain of FtsZ
Descriptor: Cell division protein SepF, ZINC ION
Authors:Sogues, A, Wehenkel, A.M, Alzari, P.M.
Deposit date:2019-07-25
Release date:2020-03-11
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Essential dynamic interdependence of FtsZ and SepF for Z-ring and septum formation in Corynebacterium glutamicum.
Nat Commun, 11, 2020
6SAT
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BU of 6sat by Molmil
Cell Division Protein SepF in complex with C-terminal domain of FtsZ
Descriptor: Cell division protein FtsZ, Cell division protein SepF
Authors:Sogues, A, Wehenkel, A.M, Alzari, P.M.
Deposit date:2019-07-17
Release date:2020-03-11
Last modified:2024-05-15
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Essential dynamic interdependence of FtsZ and SepF for Z-ring and septum formation in Corynebacterium glutamicum.
Nat Commun, 11, 2020
6SCQ
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BU of 6scq by Molmil
Cell Division Protein SepF in complex with C-terminal domain of FtsZ
Descriptor: Cell division protein SepF
Authors:Sogues, A, Wehenkel, A.M, Alzari, P.M.
Deposit date:2019-07-25
Release date:2020-03-11
Last modified:2024-05-15
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Essential dynamic interdependence of FtsZ and SepF for Z-ring and septum formation in Corynebacterium glutamicum.
Nat Commun, 11, 2020
6SCS
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BU of 6scs by Molmil
Cell Division Protein SepF in complex with C-terminal domain of FtsZ
Descriptor: Cell division protein FtsZ, Cell division protein SepF, MAGNESIUM ION
Authors:Sogues, A, Wehenkel, A.M, Alzari, P.M.
Deposit date:2019-07-25
Release date:2020-03-11
Last modified:2024-05-15
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Essential dynamic interdependence of FtsZ and SepF for Z-ring and septum formation in Corynebacterium glutamicum.
Nat Commun, 11, 2020

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数据于2024-10-16公开中

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