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2Q98

X-ray structure of a prolactin antagonist

Summary for 2Q98
Entry DOI10.2210/pdb2q98/pdb
DescriptorProlactin (2 entities in total)
Functional Keywordsantagonist receptor interaction, hormone
Biological sourceHomo sapiens (human)
Cellular locationSecreted: P01236
Total number of polymer chains1
Total formula weight22364.52
Authors
Broutin, I.J.L.,Ducruix, A.,Jomain, J.B.,Goffin, V. (deposition date: 2007-06-12, release date: 2007-09-11, Last modification date: 2023-08-30)
Primary citationJomain, J.B.,Tallet, E.,Broutin, I.,Hoos, S.,van Agthoven, J.,Ducruix, A.,Kelly, P.A.,Kragelund, B.B.,England, P.,Goffin, V.
Structural and thermodynamic bases for the design of pure prolactin receptor antagonists: X-ray structure of Del1-9-G129R-hPRL.
J.Biol.Chem., 282:33118-33131, 2007
Cited by
PubMed: 17785459
DOI: 10.1074/jbc.M704364200
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2.7 Å)
Structure validation

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