7OTQ
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![BU of 7otq by Molmil](/molmil-images/mine/7otq) | Cryo-EM structure of ALC1/CHD1L bound to a PARylated nucleosome | Descriptor: | Chromodomain-helicase-DNA-binding protein 1-like, DNA (149-MER) Widom 601 sequence, Histone H2A type 1, ... | Authors: | Bacic, L, Gaullier, G, Deindl, S. | Deposit date: | 2021-06-10 | Release date: | 2021-09-15 | Last modified: | 2024-07-17 | Method: | ELECTRON MICROSCOPY (4.8 Å) | Cite: | Structure and dynamics of the chromatin remodeler ALC1 bound to a PARylated nucleosome Elife, 10, 2021
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1ALC
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6BA8
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![BU of 6ba8 by Molmil](/molmil-images/mine/6ba8) | YbtT - Type II thioesterase from Yersiniabactin NRPS/PKS biosynthetic pathway | Descriptor: | Iron aquisition yersiniabactin synthesis enzyme, YbtT | Authors: | Brett, T.J, Kober, D.L, Ohlemacher, S.I, Henderson, J.P. | Deposit date: | 2017-10-12 | Release date: | 2018-10-31 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | YbtT is a low-specificity type II thioesterase that maintains production of the metallophore yersiniabactin in pathogenic enterobacteria. J. Biol. Chem., 293, 2018
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7Y6A
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![BU of 7y6a by Molmil](/molmil-images/mine/7y6a) | Crystal structure of Chicken Egg Lysozyme | Descriptor: | Lysozyme C, NITRATE ION | Authors: | DeMirci, H. | Deposit date: | 2022-06-18 | Release date: | 2023-04-19 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | Cryogenic X-ray crystallographic studies of biomacromolecules at Turkish Light Source " Turkish DeLight ". Turk J Biol, 47, 2023
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8Q6B
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![BU of 8q6b by Molmil](/molmil-images/mine/8q6b) | The RSL-D32N - sulfonato-calix[8]arene complex, I23 form, citrate pH 4.0, obtained by cross-seeding | Descriptor: | Fucose-binding lectin protein, GLYCEROL, beta-D-fructopyranose, ... | Authors: | Flood, R.J, Crowley, P.B. | Deposit date: | 2023-08-11 | Release date: | 2024-03-06 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (1.52 Å) | Cite: | Supramolecular Synthons in Protein-Ligand Frameworks. Cryst.Growth Des., 24, 2024
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7QXM
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7QHA
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![BU of 7qha by Molmil](/molmil-images/mine/7qha) | Cryo-EM structure of the Tripartite ATP-independent Periplasmic (TRAP) transporter SiaQM from Photobacterium profundum in amphipol | Descriptor: | Megabody c7HopQ, Putative TRAP-type C4-dicarboxylate transport system, large permease component, ... | Authors: | North, R.A, Davies, J.S, Morado, D, Dobson, R.C.J. | Deposit date: | 2021-12-11 | Release date: | 2022-12-21 | Last modified: | 2023-03-22 | Method: | ELECTRON MICROSCOPY (2.97 Å) | Cite: | Structure and mechanism of a tripartite ATP-independent periplasmic TRAP transporter. Nat Commun, 14, 2023
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6UZC
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7SVP
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2XA4
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![BU of 2xa4 by Molmil](/molmil-images/mine/2xa4) | Inhibitors of Jak2 Kinase domain | Descriptor: | 5-CHLORO-N2-[(1S)-1-(5-FLUOROPYRIMIDIN-2-YL)ETHYL]-N4-(5-METHYL-1H-PYRAZOL-3-YL)PYRIMIDINE-2,4-DIAMINE, TYROSINE-PROTEIN KINASE JAK2 | Authors: | Read, J, Green, I, Pollard, H, Howard, T, Mott, R. | Deposit date: | 2010-03-26 | Release date: | 2010-12-15 | Last modified: | 2019-05-08 | Method: | X-RAY DIFFRACTION (2.04 Å) | Cite: | Discovery of 5-Chloro-N2-[(1S)-1-(5-Fluoropyrimidin-2-Yl) Ethyl]-N4-(5-Methyl-1H-Pyrazol-3-Yl)Pyrimidine-2,4-Diamine (Azd1480) as a Novel Inhibitor of the Jak/Stat Pathway J.Med.Chem., 54, 2011
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4JF2
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4K6X
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![BU of 4k6x by Molmil](/molmil-images/mine/4k6x) | Crystal structure of disulfide oxidoreductase from Mycobacterium tuberculosis | Descriptor: | 1,4-DIETHYLENE DIOXIDE, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, Disulfide oxidoreductase | Authors: | Premkumar, L, Martin, J.L. | Deposit date: | 2013-04-16 | Release date: | 2013-10-02 | Last modified: | 2017-11-15 | Method: | X-RAY DIFFRACTION (1.972 Å) | Cite: | Rv2969c, essential for optimal growth in Mycobacterium tuberculosis, is a DsbA-like enzyme that interacts with VKOR-derived peptides and has atypical features of DsbA-like disulfide oxidases. Acta Crystallogr.,Sect.D, 69, 2013
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4GRB
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![BU of 4grb by Molmil](/molmil-images/mine/4grb) | Casein kinase 2 (CK2) bound to inhibitor | Descriptor: | 5-(2-{[4-(dimethylcarbamoyl)phenyl]amino}-4-methoxypyrimidin-5-yl)thiophene-3-carboxylic acid, CHLORIDE ION, Casein kinase II subunit alpha | Authors: | Larsen, N.A, Dowling, J.E, Ferguson, A.D. | Deposit date: | 2012-08-24 | Release date: | 2013-08-28 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.15 Å) | Cite: | Structure and Property Based Design of Pyrazolo[1,5-a]pyrimidine Inhibitors of CK2 Kinase with Activity in Vivo. ACS Med Chem Lett, 4, 2013
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2DWO
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![BU of 2dwo by Molmil](/molmil-images/mine/2dwo) | PFKFB3 in complex with ADP and PEP | Descriptor: | 6-O-phosphono-beta-D-fructofuranose, 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3, ADENOSINE-5'-DIPHOSPHATE, ... | Authors: | Lee, Y.H. | Deposit date: | 2006-08-16 | Release date: | 2007-07-03 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2.25 Å) | Cite: | A Direct Substrate-Substrate Interaction Found in the Kinase Domain of the Bifunctional Enzyme, 6-Phosphofructo-2-kinase/Fructose-2,6-bisphosphatase J.Mol.Biol., 370, 2007
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1AZF
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![BU of 1azf by Molmil](/molmil-images/mine/1azf) | CHICKEN EGG WHITE LYSOZYME CRYSTAL GROWN IN BROMIDE SOLUTION | Descriptor: | BROMIDE ION, LYSOZYME | Authors: | Lim, K, Nadarajah, A, Forsythe, E.L, Pusey, M.L. | Deposit date: | 1997-11-17 | Release date: | 1998-02-25 | Last modified: | 2023-08-02 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Locations of bromide ions in tetragonal lysozyme crystals. Acta Crystallogr.,Sect.D, 54, 1998
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7Y6D
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3RHB
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![BU of 3rhb by Molmil](/molmil-images/mine/3rhb) | Crystal structure of the apo form of glutaredoxin C5 from Arabidopsis thaliana | Descriptor: | GLUTATHIONE, Glutaredoxin-C5, chloroplastic, ... | Authors: | Roret, T, Couturier, J, Tsan, P, Jacquot, J.P, Rouhier, N, Didierjean, C. | Deposit date: | 2011-04-11 | Release date: | 2011-06-01 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (1.2 Å) | Cite: | Arabidopsis chloroplastic glutaredoxin c5 as a model to explore molecular determinants for iron-sulfur cluster binding into glutaredoxins. J.Biol.Chem., 286, 2011
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3RHC
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![BU of 3rhc by Molmil](/molmil-images/mine/3rhc) | Crystal structure of the holo form of glutaredoxin C5 from Arabidopsis thaliana | Descriptor: | FE2/S2 (INORGANIC) CLUSTER, GLUTATHIONE, Glutaredoxin-C5, ... | Authors: | Roret, T, Couturier, J, Tsan, P, Jacquot, J.P, Rouhier, N, Didierjean, C. | Deposit date: | 2011-04-11 | Release date: | 2011-06-01 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Arabidopsis chloroplastic glutaredoxin c5 as a model to explore molecular determinants for iron-sulfur cluster binding into glutaredoxins. J.Biol.Chem., 286, 2011
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2DWP
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![BU of 2dwp by Molmil](/molmil-images/mine/2dwp) | A pseudo substrate complex of 6-phosphofructo-2-kinase of PFKFB | Descriptor: | 6-O-phosphono-beta-D-fructofuranose, 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3, MAGNESIUM ION, ... | Authors: | Lee, Y.H. | Deposit date: | 2006-08-16 | Release date: | 2007-07-03 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | A Direct Substrate-Substrate Interaction Found in the Kinase Domain of the Bifunctional Enzyme, 6-Phosphofructo-2-kinase/Fructose-2,6-bisphosphatase J.Mol.Biol., 370, 2007
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8Q6C
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![BU of 8q6c by Molmil](/molmil-images/mine/8q6c) | The RSL-D32N - sulfonato-calix[8]arene complex, P63 form, acetate pH 4.0 | Descriptor: | Fucose-binding lectin protein, GLYCEROL, beta-D-fructopyranose, ... | Authors: | Flood, R.J, Crowley, P.B. | Deposit date: | 2023-08-11 | Release date: | 2024-03-06 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (1.38 Å) | Cite: | Supramolecular Synthons in Protein-Ligand Frameworks. Cryst.Growth Des., 24, 2024
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8Q6A
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![BU of 8q6a by Molmil](/molmil-images/mine/8q6a) | The RSL-D32N - sulfonato-calix[8]arene complex, I213 form, citrate pH 4.0 | Descriptor: | Fucose-binding lectin protein, GLYCEROL, beta-D-fructopyranose, ... | Authors: | Flood, R.J, Crowley, P.B. | Deposit date: | 2023-08-11 | Release date: | 2024-03-06 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (2.61 Å) | Cite: | Supramolecular Synthons in Protein-Ligand Frameworks. Cryst.Growth Des., 24, 2024
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1KOS
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![BU of 1kos by Molmil](/molmil-images/mine/1kos) | SOLUTION NMR STRUCTURE OF AN ANALOG OF THE YEAST TRNA PHE T STEM LOOP CONTAINING RIBOTHYMIDINE AT ITS NATURALLY OCCURRING POSITION | Descriptor: | 5'-R(*CP*UP*GP*UP*GP*(5MU)P*UP*CP*GP*AP*UP*(CH)P*CP*AP*CP*AP*G)- 3' | Authors: | Koshlap, K.M, Guenther, R, Sochacka, E, Malkiewicz, A, Agris, P.F. | Deposit date: | 1999-05-03 | Release date: | 1999-10-22 | Last modified: | 2023-12-27 | Method: | SOLUTION NMR | Cite: | A distinctive RNA fold: the solution structure of an analogue of the yeast tRNAPhe T Psi C domain. Biochemistry, 38, 1999
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1XZW
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![BU of 1xzw by Molmil](/molmil-images/mine/1xzw) | Sweet potato purple acid phosphatase/phosphate complex | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, FE (III) ION, ... | Authors: | Schenk, G, Carrington, L.E, Gahan, L.R, Hamilton, S.E, de Jersey, J, Guddat, L.W. | Deposit date: | 2004-11-12 | Release date: | 2004-12-14 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Phosphate forms an unusual tripodal complex with the Fe-Mn center of sweet potato purple acid phosphatase Proc.Natl.Acad.Sci.USA, 102, 2005
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4IWV
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![BU of 4iwv by Molmil](/molmil-images/mine/4iwv) | Crystals structure of Human Glucokinase in complex with small molecule activator | Descriptor: | (2S)-2-{[1-(2-chlorophenyl)-1H-pyrazolo[3,4-d]pyrimidin-4-yl]oxy}-N-(5-chloropyridin-2-yl)-3-(2-hydroxyethoxy)propanamide, Glucokinase isoform 3, SODIUM ION, ... | Authors: | Ogg, D.J, Hargreaves, D, Gerhardt, S, Flavell, L, McAlister, M. | Deposit date: | 2013-01-24 | Release date: | 2013-04-24 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Optimising pharmacokinetics of glucokinase activators with matched triplicate design sets the discovery of AZD3651 and AZD9485 To be Published
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8CVT
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![BU of 8cvt by Molmil](/molmil-images/mine/8cvt) | Human 19S-20S proteasome, state SD2 | Descriptor: | 26S protease regulatory subunit 10B, 26S protease regulatory subunit 8, 26S proteasome complex subunit SEM1, ... | Authors: | Zhao, J. | Deposit date: | 2022-05-18 | Release date: | 2022-11-02 | Method: | ELECTRON MICROSCOPY (3 Å) | Cite: | Structural insights into the human PA28-20S proteasome enabled by efficient tagging and purification of endogenous proteins. Proc.Natl.Acad.Sci.USA, 119, 2022
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