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5Z07
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BU of 5z07 by Molmil
Crystal structure of centromere protein Cenp-I
Descriptor: Cenp-I
Authors:Tian, W, Hu, L.Q, He, X.
Deposit date:2017-12-18
Release date:2018-10-31
Last modified:2019-05-15
Method:X-RAY DIFFRACTION (2.298 Å)
Cite:Structural analysis of fungal CENP-H/I/K homologs reveals a conserved assembly mechanism underlying proper chromosome alignment.
Nucleic Acids Res., 47, 2019
4HGO
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BU of 4hgo by Molmil
2-keto-3-deoxy-D-glycero-D-galactonononate-9-phosphate phosphohydrolase from Bacteroides thetaiotaomicron in complex with transition state mimic
Descriptor: MAGNESIUM ION, acylneuraminate cytidylyltransferase, deamino-beta-neuraminic acid, ...
Authors:Daughtry, K.D, Allen, K.N.
Deposit date:2012-10-08
Release date:2013-08-21
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structural Basis for the Divergence of Substrate Specificity and Biological Function within HAD Phosphatases in Lipopolysaccharide and Sialic Acid Biosynthesis.
Biochemistry, 52, 2013
4HGR
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BU of 4hgr by Molmil
Crystal structure of E56A/K67A mutant of 2-keto-3-deoxy-D-glycero-D-galactonononate-9-phosphate phosphohydrolase from Bacteroides thetaiotaomicron
Descriptor: Acylneuraminate cytidylyltransferase, MAGNESIUM ION
Authors:Daughtry, K.D, Allen, K.N.
Deposit date:2012-10-08
Release date:2013-08-21
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:Structural Basis for the Divergence of Substrate Specificity and Biological Function within HAD Phosphatases in Lipopolysaccharide and Sialic Acid Biosynthesis.
Biochemistry, 52, 2013
4HGN
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BU of 4hgn by Molmil
Crystal Structure of 2-keto-3-deoxyoctulosonate 8-phosphate PHOSPHOHYDROLASE from Bacteroides thetaiotaomicron
Descriptor: 2-keto-3-deoxy-D-manno-octulosonate 8-phosphate phosphohydrolase, FORMIC ACID, MAGNESIUM ION
Authors:Daughtry, K.D, Allen, K.N.
Deposit date:2012-10-08
Release date:2013-08-21
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structural Basis for the Divergence of Substrate Specificity and Biological Function within HAD Phosphatases in Lipopolysaccharide and Sialic Acid Biosynthesis.
Biochemistry, 52, 2013
5BSA
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BU of 5bsa by Molmil
Structure of histone H3/H4 in complex with Spt2
Descriptor: Histone H3.2, Histone H4, Protein SPT2 homolog
Authors:Chen, S, Patel, D.J.
Deposit date:2015-06-01
Release date:2015-07-08
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (4.611 Å)
Cite:Structure-function studies of histone H3/H4 tetramer maintenance during transcription by chaperone Spt2.
Genes Dev., 29, 2015
5BS7
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BU of 5bs7 by Molmil
Structure of histone H3/H4 in complex with Spt2
Descriptor: Histone H3.2, Histone H4, Protein SPT2 homolog, ...
Authors:Chen, S, Patel, D.J.
Deposit date:2015-06-01
Release date:2015-07-08
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (3.3 Å)
Cite:Structure-function studies of histone H3/H4 tetramer maintenance during transcription by chaperone Spt2.
Genes Dev., 29, 2015
7VJN
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BU of 7vjn by Molmil
Crystal structure of anti-CRISPR-associated protein Aca1 in Pseudomonas phage JBD30
Descriptor: anti-CRISPR-associated protein Aca1
Authors:Liu, Y.H, Zhang, L.S, Wu, B.X, Huang, H.D.
Deposit date:2021-09-28
Release date:2021-10-13
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (1.799 Å)
Cite:Structural basis for anti-CRISPR repression mediated by bacterial operon proteins Aca1 and Aca2.
J.Biol.Chem., 297, 2021
4HGP
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BU of 4hgp by Molmil
Crystal Structure of 2-keto-3-deoxyoctulosonate 8-phosphate phosphohydrolase from Haemophilus influenzae in complex with transition state mimic
Descriptor: 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase KdsC, 3-deoxy-alpha-D-manno-oct-2-ulopyranosonic acid, MAGNESIUM ION, ...
Authors:Daughtry, K.D, Allen, K.N.
Deposit date:2012-10-08
Release date:2013-08-21
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structural Basis for the Divergence of Substrate Specificity and Biological Function within HAD Phosphatases in Lipopolysaccharide and Sialic Acid Biosynthesis.
Biochemistry, 52, 2013
4HGQ
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BU of 4hgq by Molmil
Crystal structure of E56A mutant of 2-keto-3-deoxy-D-glycero-D-galactonononate-9-phosphate phosphohydrolase from Bacteroides thetaiotaomicron
Descriptor: Acylneuraminate cytidylyltransferase, MAGNESIUM ION
Authors:Daughtry, K.D, Allen, K.N.
Deposit date:2012-10-08
Release date:2013-08-21
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.28 Å)
Cite:Structural Basis for the Divergence of Substrate Specificity and Biological Function within HAD Phosphatases in Lipopolysaccharide and Sialic Acid Biosynthesis.
Biochemistry, 52, 2013
4KSJ
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BU of 4ksj by Molmil
Crystal structure of the OTU domain of Gumby/Fam105B at 1.6 angstrom
Descriptor: BETA-MERCAPTOETHANOL, GLYCEROL, Protein FAM105B
Authors:Ceccarelli, D.F, Juang, Y.-C, Sicheri, F.
Deposit date:2013-05-17
Release date:2013-06-05
Last modified:2018-04-18
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:The linear ubiquitin-specific deubiquitinase gumby regulates angiogenesis.
Nature, 498, 2013
4KSK
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BU of 4ksk by Molmil
Gumby/Fam105B in complex with ubiquitin
Descriptor: Polyubiquitin-C, Protein FAM105B, SULFATE ION
Authors:Ceccarelli, D.F, Juang, Y.-C, Sicheri, F.
Deposit date:2013-05-17
Release date:2013-06-05
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:The linear ubiquitin-specific deubiquitinase gumby regulates angiogenesis.
Nature, 498, 2013
4KSL
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BU of 4ksl by Molmil
Gumby/Fam105B in complex with linear di-ubiquitin
Descriptor: Polyubiquitin-C, Protein FAM105B
Authors:Juang, Y.-C, Ceccarelli, D.F, Sicheri, F.
Deposit date:2013-05-17
Release date:2013-06-05
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (2.83 Å)
Cite:The linear ubiquitin-specific deubiquitinase gumby regulates angiogenesis.
Nature, 498, 2013
3T7K
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BU of 3t7k by Molmil
Complex structure of Rtt107p and phosphorylated histone H2A
Descriptor: Histone H2A.1, Regulator of Ty1 transposition protein 107
Authors:Li, X, Li, F, Wu, J, Shi, Y.
Deposit date:2011-07-30
Release date:2012-02-15
Last modified:2017-11-08
Method:X-RAY DIFFRACTION (2.028 Å)
Cite:Structure of C-terminal Tandem BRCT Repeats of Rtt107 Protein Reveals Critical Role in Interaction with Phosphorylated Histone H2A during DNA Damage Repair
J.Biol.Chem., 287, 2012
3T7I
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BU of 3t7i by Molmil
Crystal structure of Se-Met Rtt107p (residues 820-1070)
Descriptor: Regulator of Ty1 transposition protein 107
Authors:Li, X, Li, F, Wu, J, Shi, Y.
Deposit date:2011-07-30
Release date:2012-02-15
Last modified:2017-11-08
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structure of C-terminal Tandem BRCT Repeats of Rtt107 Protein Reveals Critical Role in Interaction with Phosphorylated Histone H2A during DNA Damage Repair
J.Biol.Chem., 287, 2012
7DQZ
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BU of 7dqz by Molmil
Crystal structure of SARS 3C-like protease in apo form
Descriptor: 3C-like proteinase
Authors:Zhang, Y.T, Gao, H.X, Zhou, H, Zhong, F.L, Hu, X.H, Zhou, X.L, Lin, C, Wang, Q.S, Li, J, Zhang, J.
Deposit date:2020-12-24
Release date:2021-09-29
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (1.99 Å)
Cite:Structure-Based Discovery and Structural Basis of a Novel Broad-Spectrum Natural Product against the Main Protease of Coronavirus.
J.Virol., 96, 2022
7VCQ
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BU of 7vcq by Molmil
structure of viral protein BKRF4 in complex with H3.3-H4-ASF1
Descriptor: Histone H3.3, Histone H4, Histone chaperone ASF1B, ...
Authors:Liu, Y.R.
Deposit date:2021-09-03
Release date:2022-08-03
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (3 Å)
Cite:Epstein-Barr Virus Tegument Protein BKRF4 is a Histone Chaperone.
J.Mol.Biol., 434, 2022
7VCL
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BU of 7vcl by Molmil
structure of viral protein BKRF4 in complex with H2A-H2B
Descriptor: Tegument protein BKRF4, histone H2A-H2B
Authors:Liu, Y.R.
Deposit date:2021-09-03
Release date:2022-08-03
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Epstein-Barr Virus Tegument Protein BKRF4 is a Histone Chaperone.
J.Mol.Biol., 434, 2022
7EO7
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BU of 7eo7 by Molmil
Crystal structure of HCoV-NL63 3C-like protease in complex with an inhibitor Shikonin
Descriptor: 2-[(1R)-4-methyl-1-oxidanyl-pent-3-enyl]-5,8-bis(oxidanyl)naphthalene-1,4-dione, 3C-like proteinase
Authors:Gao, H.X, Zhang, Y.T, Zhou, X.L, Zhong, F.L, Li, J, Zhang, J.
Deposit date:2021-04-21
Release date:2021-10-20
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.24916625 Å)
Cite:Structure-Based Discovery and Structural Basis of a Novel Broad-Spectrum Natural Product against the Main Protease of Coronavirus.
J.Virol., 96, 2022
7EO8
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BU of 7eo8 by Molmil
Crystal structure of SARS coronavirus main protease in complex with an inhibitor Shikonin
Descriptor: 2-[(1R)-4-methyl-1-oxidanyl-pent-3-enyl]-5,8-bis(oxidanyl)naphthalene-1,4-dione, 3C-like proteinase
Authors:Zhang, Y.T, Gao, H.X, Zhou, H, Zhong, F.L, Hu, X.H, Zhou, X.L, Lin, C, Wang, Q.S, Li, J, Zhang, J.
Deposit date:2021-04-21
Release date:2021-10-20
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.2808516 Å)
Cite:Structure-Based Discovery and Structural Basis of a Novel Broad-Spectrum Natural Product against the Main Protease of Coronavirus.
J.Virol., 96, 2022
3T7J
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BU of 3t7j by Molmil
Crystal structure of Rtt107p (residues 820-1070)
Descriptor: Regulator of Ty1 transposition protein 107
Authors:Li, X, Li, F, Wu, J, Shi, Y.
Deposit date:2011-07-30
Release date:2012-02-15
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (2.042 Å)
Cite:Structure of C-terminal Tandem BRCT Repeats of Rtt107 Protein Reveals Critical Role in Interaction with Phosphorylated Histone H2A during DNA Damage Repair
J.Biol.Chem., 287, 2012
7X08
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BU of 7x08 by Molmil
S protein of SARS-CoV-2 in complex with 2G1
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, LINOLEIC ACID, ...
Authors:Guo, Y.Y, Zhang, Y.Y, Zhou, Q.
Deposit date:2022-02-21
Release date:2022-03-09
Last modified:2023-11-15
Method:ELECTRON MICROSCOPY (2.7 Å)
Cite:Broad ultra-potent neutralization of SARS-CoV-2 variants by monoclonal antibodies specific to the tip of RBD.
Cell Discov, 8, 2022
6ZYT
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BU of 6zyt by Molmil
Monomeric streptavidin with a conjugated biotinylated pyrrolidine
Descriptor: 5-((3aS,4S,6aR)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl)-N-((S)-pyrrolidin-3-yl)pentanamide, SULFATE ION, Streptavidin/Rhizavidin Hybrid
Authors:Nodling, A.R, Lipka-Lloyd, M, Tsai, Y.H, Rizkallah, P, Luk, L.Y.P, Jin, Y.
Deposit date:2020-08-03
Release date:2021-08-18
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:The role of streptavidin and its variants in catalysis by biotinylated secondary amines.
Org.Biomol.Chem., 19, 2021
8JF4
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BU of 8jf4 by Molmil
The crystal structure of human AURKA kinase domain in complex with AURKA-compound 9
Descriptor: 2-[4-[4-[bis(oxidanylidene)-$l^5-sulfanyl]oxyphenyl]carbonylpiperazin-1-yl]-6-[(5-cyclopropyl-1H-pyrazol-3-yl)amino]-N-prop-2-ynyl-pyrimidine-4-carboxamide, Aurora kinase A
Authors:Zhu, C.J.
Deposit date:2023-05-17
Release date:2024-02-14
Last modified:2024-03-27
Method:X-RAY DIFFRACTION (2.89288354 Å)
Cite:Global Reactivity Profiling of the Catalytic Lysine in Human Kinome for Covalent Inhibitor Development.
Angew.Chem.Int.Ed.Engl., 63, 2024
6A52
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BU of 6a52 by Molmil
Oxidase ChaP-H1
Descriptor: FE (II) ION, dioxidase ChaP-H1
Authors:Zhang, B, Ge, H.M.
Deposit date:2018-06-21
Release date:2018-08-29
Last modified:2024-03-27
Method:X-RAY DIFFRACTION (2 Å)
Cite:Molecular Basis for the Final Oxidative Rearrangement Steps in Chartreusin Biosynthesis.
J. Am. Chem. Soc., 140, 2018
8JG8
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BU of 8jg8 by Molmil
The crystal structure of human aurka kinase domain in the complex with aurka-compound 25
Descriptor: 4-[5-[3-[bis(oxidanylidene)-$l^5-sulfanyl]oxyphenyl]-7H-pyrrolo[2,3-d]pyrimidin-4-yl]morpholine, Aurora kinase A
Authors:Zhu, C.J, Zhang, Z.M.
Deposit date:2023-05-19
Release date:2024-04-17
Method:X-RAY DIFFRACTION (2.90002346 Å)
Cite:Global Reactivity Profiling of the Catalytic Lysine in Human Kinome for Covalent Inhibitor Development.
Angew.Chem.Int.Ed.Engl., 63, 2024

225399

数据于2024-09-25公开中

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