4HGO

2-keto-3-deoxy-D-glycero-D-galactonononate-9-phosphate phosphohydrolase from Bacteroides thetaiotaomicron in complex with transition state mimic

Summary for 4HGO

Entry DOI	10.2210/pdb4hgo/pdb
Related	3e8m 4HGN 4HGP 4HGQ 4HGR
Descriptor	acylneuraminate cytidylyltransferase, MAGNESIUM ION, oxido(dioxo)vanadium, ... (5 entities in total)
Functional Keywords	rossmann fold, phosphohydroylase, transferase, hydrolase
Biological source	Bacteroides thetaiotaomicron
Total number of polymer chains	4
Total formula weight	74477.67
Authors	Daughtry, K.D.,Allen, K.N. (deposition date: 2012-10-08, release date: 2013-08-21, Last modification date: 2023-09-20)
Primary citation	Daughtry, K.D.,Huang, H.,Malashkevich, V.,Patskovsky, Y.,Liu, W.,Ramagopal, U.,Sauder, J.M.,Burley, S.K.,Almo, S.C.,Dunaway-Mariano, D.,Allen, K.N. Structural Basis for the Divergence of Substrate Specificity and Biological Function within HAD Phosphatases in Lipopolysaccharide and Sialic Acid Biosynthesis. Biochemistry, 52:5372-5386, 2013 Cited by PubMed: 23848398 DOI: 10.1021/bi400659k PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.1 Å)

Structure validation