4HGR

Crystal structure of E56A/K67A mutant of 2-keto-3-deoxy-D-glycero-D-galactonononate-9-phosphate phosphohydrolase from Bacteroides thetaiotaomicron

Summary for 4HGR

Entry DOI	10.2210/pdb4hgr/pdb
Related	3e8m 4HGN 4HGO 4HGP 4HGQ
Descriptor	Acylneuraminate cytidylyltransferase, MAGNESIUM ION (3 entities in total)
Functional Keywords	rossmann fold, phosphohydroylase, transferase, hydrolase
Biological source	Bacteroides thetaiotaomicron (2-keto-3-deoxy-D-glycero-D-galactonononate-9-phosphate phosphohydrolase)
Total number of polymer chains	8
Total formula weight	146161.85
Authors	Daughtry, K.D.,Allen, K.N. (deposition date: 2012-10-08, release date: 2013-08-21, Last modification date: 2023-09-20)
Primary citation	Daughtry, K.D.,Huang, H.,Malashkevich, V.,Patskovsky, Y.,Liu, W.,Ramagopal, U.,Sauder, J.M.,Burley, S.K.,Almo, S.C.,Dunaway-Mariano, D.,Allen, K.N. Structural Basis for the Divergence of Substrate Specificity and Biological Function within HAD Phosphatases in Lipopolysaccharide and Sialic Acid Biosynthesis. Biochemistry, 52:5372-5386, 2013 Cited by PubMed: 23848398 DOI: 10.1021/bi400659k PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.05 Å)

Structure validation