6MPG
 
 | | Cryo-EM structure at 3.2 A resolution of HIV-1 fusion peptide-directed antibody, A12V163-b.01, elicited by vaccination of Rhesus macaques, in complex with stabilized HIV-1 Env BG505 DS-SOSIP, which was also bound to antibodies VRC03 and PGT122 | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, A12V163-b.01 Heavy Chain, ... | | Authors: | Acharya, P, Kwong, P.D. | | Deposit date: | 2018-10-06 | | Release date: | 2019-07-24 | | Last modified: | 2020-07-29 | | Method: | ELECTRON MICROSCOPY (3.2 Å) | | Cite: | Antibody Lineages with Vaccine-Induced Antigen-Binding Hotspots Develop Broad HIV Neutralization.
Cell, 178, 2019
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6MQE
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6MQS
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6NF2
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8CX9
 | | Structure of the SARS-COV2 PLpro (C111S) in complex with a dimeric Ubv that inhibits activity by an unusual allosteric mechanism | | Descriptor: | BROMIDE ION, CHLORIDE ION, Papain-like protease nsp3, ... | | Authors: | Singer, A.U, Slater, C.L, Patel, A, Russel, R, Mark, B.L, Sidhu, S.S. | | Deposit date: | 2022-05-20 | | Release date: | 2023-01-25 | | Last modified: | 2023-10-25 | | Method: | X-RAY DIFFRACTION (3.5 Å) | | Cite: | Ubiquitin variants potently inhibit SARS-CoV-2 PLpro and viral replication via a novel site distal to the protease active site.
Plos Pathog., 18, 2022
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4KSY
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4N2S
 | | Crystal Structure of THA8 in complex with Zm1a-6 RNA | | Descriptor: | THA8 RNA binding protein, Zm1a-6 RNA | | Authors: | Ke, J, Chen, R.Z, Ban, T, Zhou, X.E, Gu, X, Brunzelle, J.S, Zhu, J.K, Melcher, K, Xu, H.E. | | Deposit date: | 2013-10-06 | | Release date: | 2013-10-30 | | Last modified: | 2024-04-03 | | Method: | X-RAY DIFFRACTION (3 Å) | | Cite: | Structural basis for RNA recognition by a dimeric PPR-protein complex.
Nat.Struct.Mol.Biol., 20, 2013
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4N2Q
 | | Crystal structure of THA8 in complex with Zm4 RNA | | Descriptor: | RNA (5'-R(*AP*AP*GP*AP*AP*GP*AP*AP*AP*UP*UP*GP*G)-3'), THA8 RNA binding protein | | Authors: | Ke, J, Chen, R.Z, Ban, T, Zhou, X.E, Gu, X, Brunzelle, J.S, Zhu, J.K, Melcher, K, Xu, H.E. | | Deposit date: | 2013-10-06 | | Release date: | 2013-10-30 | | Last modified: | 2024-04-03 | | Method: | X-RAY DIFFRACTION (2.8 Å) | | Cite: | Structural basis for RNA recognition by a dimeric PPR-protein complex.
Nat.Struct.Mol.Biol., 20, 2013
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5A2T
 | | The Molecular Basis for Flexibility in the Flexible Filamentous Plant Viruses | | Descriptor: | BAMBOO MOSAIC VIRUS, COAT PROTEIN | | Authors: | DiMaio, F, Chen, C.C, Yu, X, Frenz, B, Hsu, Y.H, Lin, N.S, Egelman, E.H. | | Deposit date: | 2015-05-23 | | Release date: | 2015-07-22 | | Last modified: | 2024-05-08 | | Method: | ELECTRON MICROSCOPY (5.6 Å) | | Cite: | The Molecular Basis for Flexibility in the Flexible Filamentous Plant Viruses.
Nat.Struct.Mol.Biol., 22, 2015
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8GAS
 | | vFP48.02 Fab in complex with BG505 DS-SOSIP Env trimer | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Envelope glycoprotein gp120, ... | | Authors: | Gorman, J, Kwong, P.D. | | Deposit date: | 2023-02-23 | | Release date: | 2023-04-19 | | Last modified: | 2023-06-14 | | Method: | ELECTRON MICROSCOPY (4.04 Å) | | Cite: | Diverse Murine Vaccinations Reveal Distinct Antibody Classes to Target Fusion Peptide and Variation in Peptide Length to Improve HIV Neutralization.
J.Virol., 97, 2023
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8G85
 | | vFP52.02 Fab in complex with BG505 DS-SOSIP Env trimer | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Envelope glycoprotein gp120, ... | | Authors: | Gorman, J, Kwong, P.D. | | Deposit date: | 2023-02-17 | | Release date: | 2023-04-19 | | Last modified: | 2023-06-14 | | Method: | ELECTRON MICROSCOPY (3.99 Å) | | Cite: | Diverse Murine Vaccinations Reveal Distinct Antibody Classes to Target Fusion Peptide and Variation in Peptide Length to Improve HIV Neutralization.
J.Virol., 97, 2023
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8G9W
 | | Cryo-EM structure of vFP49.02 Fab in complex with HIV-1 Env BG505 DS-SOSIP.664 (conformation 1) | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Envelope glycoprotein gp120, ... | | Authors: | Changela, A, Gorman, J, Kwong, P.D. | | Deposit date: | 2023-02-22 | | Release date: | 2023-04-19 | | Last modified: | 2023-06-14 | | Method: | ELECTRON MICROSCOPY (4.66 Å) | | Cite: | Diverse Murine Vaccinations Reveal Distinct Antibody Classes to Target Fusion Peptide and Variation in Peptide Length to Improve HIV Neutralization.
J.Virol., 97, 2023
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8G9Y
 | | Cryo-EM structure of vFP49.02 Fab in complex with HIV-1 Env BG505 DS-SOSIP.664 (conformation 3) | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Envelope glycoprotein gp120, ... | | Authors: | Changela, A, Gorman, J, Kwong, P.D. | | Deposit date: | 2023-02-22 | | Release date: | 2023-04-19 | | Last modified: | 2023-06-14 | | Method: | ELECTRON MICROSCOPY (4.28 Å) | | Cite: | Diverse Murine Vaccinations Reveal Distinct Antibody Classes to Target Fusion Peptide and Variation in Peptide Length to Improve HIV Neutralization.
J.Virol., 97, 2023
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8G9X
 | | Cryo-EM structure of vFP49.02 Fab in complex with HIV-1 Env BG505 DS-SOSIP.664 (conformation 2) | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Envelope glycoprotein gp120, ... | | Authors: | Changela, A, Gorman, J, Kwong, P.D. | | Deposit date: | 2023-02-22 | | Release date: | 2023-04-19 | | Last modified: | 2023-06-14 | | Method: | ELECTRON MICROSCOPY (4.46 Å) | | Cite: | Diverse Murine Vaccinations Reveal Distinct Antibody Classes to Target Fusion Peptide and Variation in Peptide Length to Improve HIV Neutralization.
J.Virol., 97, 2023
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3BY7
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8CQI
 | | Human heparanase in complex with inhibitor R3794 | | Descriptor: | (3~{S},4~{S})-4,5,5-tris(oxidanyl)piperidine-3-carboxylic acid, 1,2-ETHANEDIOL, 1,5-anhydro-D-arabinitol, ... | | Authors: | Moran, E.M, Davies, G.J, Chen, C, Nieuwendijk, E.V, Wu, L, Skoulikopoulou, F, Riet, V.V, Overkleeft, H.S, Armstrong, Z. | | Deposit date: | 2023-03-06 | | Release date: | 2024-01-10 | | Last modified: | 2024-01-24 | | Method: | X-RAY DIFFRACTION (2.1 Å) | | Cite: | Molecular Basis for Inhibition of Heparanases and beta-Glucuronidases by Siastatin B.
J.Am.Chem.Soc., 146, 2024
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8FSL
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8FAQ
 | | Structure of Hemagglutinin from Influenza A/Victoria/22/2020 | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin | | Authors: | Hernandez Garcia, A, Lei, R. | | Deposit date: | 2022-11-28 | | Release date: | 2024-06-19 | | Last modified: | 2024-07-24 | | Method: | X-RAY DIFFRACTION (2.035 Å) | | Cite: | Epistasis mediates the evolution of the receptor binding mode in recent human H3N2 hemagglutinin.
Nat Commun, 15, 2024
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8FAW
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2DUA
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6EET
 | | Crystal structure of mouse Protocadherin-15 EC9-MAD12 | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, CALCIUM ION, ... | | Authors: | Narui, Y, Sotomayor, M. | | Deposit date: | 2018-08-15 | | Release date: | 2019-08-21 | | Last modified: | 2023-10-11 | | Method: | X-RAY DIFFRACTION (3.23 Å) | | Cite: | Structural determinants of protocadherin-15 mechanics and function in hearing and balance perception.
Proc.Natl.Acad.Sci.USA, 2020
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6E8F
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6EB5
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8YZ7
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3DEE
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