3PS5
 
 | | Crystal structure of the full-length Human Protein Tyrosine Phosphatase SHP-1 | | Descriptor: | SULFATE ION, Tyrosine-protein phosphatase non-receptor type 6 | | Authors: | Wang, W, Liu, L, Song, X, Mo, Y, Komma, C, Bellamy, H.D, Zhao, Z.J, Zhou, G.W. | | Deposit date: | 2010-11-30 | | Release date: | 2011-04-20 | | Last modified: | 2023-09-06 | | Method: | X-RAY DIFFRACTION (3.1 Å) | | Cite: | Crystal structure of human protein tyrosine phosphatase SHP-1 in the open conformation.
J.Cell.Biochem., 112, 2011
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8IYA
 | | Complex of SETDB1-derived peptide bound to UBE2E1 | | Descriptor: | Histone-lysine N-methyltransferase SETDB1, SULFATE ION, Ubiquitin-conjugating enzyme E2 E1 | | Authors: | Du, Y.X, Liu, L. | | Deposit date: | 2023-04-04 | | Release date: | 2024-01-03 | | Method: | X-RAY DIFFRACTION (2.43 Å) | | Cite: | Complex of SETDB1-derived peptide bound to UBE2E1
To Be Published
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8J1P
 | | Cryo-EM structure of Ufd4 in complex with K29/48 triUb | | Descriptor: | Ubiquitin, Ubiquitin fusion degradation protein 4 | | Authors: | Ai, H.S, Mao, J.X, Wu, X.W, Pan, M, Liu, L. | | Deposit date: | 2023-04-13 | | Release date: | 2024-04-17 | | Method: | ELECTRON MICROSCOPY (3.31 Å) | | Cite: | Structural Insights into the Molecular Mechanism of Ufd4-catalyzed Elongation of K48-linked Ubiquitin Chain through Lys29 Linkage
To Be Published
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8J1R
 | | cryo-EM structures of Ufd4 in complex with Ubc4-Ub | | Descriptor: | Ubiquitin fusion degradation protein 4, Ubiquitin-conjugating enzyme E2 4 | | Authors: | Ai, H.S, Mao, J.X, Wu, X.W, Cai, H.Y, Pan, M, Liu, L. | | Deposit date: | 2023-04-13 | | Release date: | 2024-04-17 | | Method: | ELECTRON MICROSCOPY (3.52 Å) | | Cite: | Structural Visualization of HECT-E3 Ufd4 accepting and transferring Ubiquitin to Form K29/K48-branched Polyubiquitination on N-degron. bioRxiv,doi: ttps://doi.org/10.1101/2023.05.23.542033
To Be Published
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5YKJ
 | | Structural basis of the thiol resolving mechanism in yeast mitochondrial 1-Cys peroxiredoxin via glutathione/thioredoxin systems | | Descriptor: | GLYCEROL, Peroxiredoxin PRX1, mitochondrial, ... | | Authors: | Li, C.C, Yang, J, Yang, M.J, Liu, L, Peng, C.T, Li, T, He, L.H, Song, Y.J, Zhu, Y.B, Zhao, N.L, Zhao, C, Bao, R. | | Deposit date: | 2017-10-14 | | Release date: | 2018-10-24 | | Last modified: | 2019-11-06 | | Method: | X-RAY DIFFRACTION (1.53 Å) | | Cite: | Structural basis of the thiol resolving mechanism in yeast mitochondrial 1-Cys peroxiredoxin via glutathione/thioredoxin systems
To be published
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5YKW
 | | Structural basis of the thiol resolving mechanism in yeast mitochondrial 1-Cys peroxiredoxin via glutathione/thioredoxin systems | | Descriptor: | Thioredoxin-3, mitochondrial, peptide THR-PRO-VAL-CYS-THR-THR-GLU-VAL | | Authors: | Li, C.C, Yang, J, Yang, M.J, Liu, L, Peng, C.T, Li, T, He, L.H, Song, Y.J, Zhu, Y.B, Zhao, N.L, Zhao, C, Bao, R. | | Deposit date: | 2017-10-16 | | Release date: | 2018-10-24 | | Last modified: | 2019-11-06 | | Method: | X-RAY DIFFRACTION (2.08 Å) | | Cite: | Structural basis of the thiol resolving mechanism in yeast mitochondrial 1-Cys peroxiredoxin via glutathione/thioredoxin systems
to be published
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5ZTE
 | | Crystal structure of PrxA C119S mutant from Arabidopsis thaliana | | Descriptor: | 2-Cys peroxiredoxin BAS1, chloroplastic | | Authors: | Yang, Y, Cai, W, Wang, J, Pan, W, Liu, L, Wang, M, Zhang, M. | | Deposit date: | 2018-05-03 | | Release date: | 2018-10-10 | | Last modified: | 2023-11-22 | | Method: | X-RAY DIFFRACTION (2.6 Å) | | Cite: | Crystal structure of Arabidopsis thaliana peroxiredoxin A C119S mutant.
Acta Crystallogr F Struct Biol Commun, 74, 2018
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7CRD
 | | Structure of Pseudomonas aeruginosa OdaA | | Descriptor: | Probable enoyl-CoA hydratase/isomerase | | Authors: | Zhao, N, Zhao, C, Liu, L, Li, T, Li, C, He, L, Zhu, Y, Song, Y, Bao, R. | | Deposit date: | 2020-08-13 | | Release date: | 2020-09-16 | | Last modified: | 2023-11-29 | | Method: | X-RAY DIFFRACTION (1.901 Å) | | Cite: | Structural and molecular dynamic studies of Pseudomonas aeruginosa OdaA reveal the regulation role of a C-terminal hinge element.
Biochim Biophys Acta Gen Subj, 1865, 2020
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4QDJ
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4QDK
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4QS9
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4QS8
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4QS7
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4RIY
 | | Crystal structure of an EGFR/HER3 kinase domain heterodimer containing the cancer-associated HER3-E909G mutation | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, Epidermal growth factor receptor, MAGNESIUM ION, ... | | Authors: | Littlefield, P, Liu, L, Jura, N. | | Deposit date: | 2014-10-07 | | Release date: | 2014-12-10 | | Last modified: | 2023-09-20 | | Method: | X-RAY DIFFRACTION (2.981 Å) | | Cite: | Structural analysis of the EGFR/HER3 heterodimer reveals the molecular basis for activating HER3 mutations.
Sci.Signal., 7, 2014
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4RIX
 | | Crystal structure of an EGFR/HER3 kinase domain heterodimer containing the cancer-associated HER3-Q790R mutation | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, Epidermal growth factor receptor, MAGNESIUM ION, ... | | Authors: | Littlefield, P, Liu, L, Jura, N. | | Deposit date: | 2014-10-07 | | Release date: | 2014-12-10 | | Last modified: | 2023-09-20 | | Method: | X-RAY DIFFRACTION (3.1 Å) | | Cite: | Structural analysis of the EGFR/HER3 heterodimer reveals the molecular basis for activating HER3 mutations.
Sci.Signal., 7, 2014
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8IRK
 | | Carbon Sulfoxide lyase | | Descriptor: | PYRIDOXAL-5'-PHOSPHATE, PYRUVIC ACID, Probable hercynylcysteine sulfoxide lyase | | Authors: | Gong, W.M, Wei, L.L, Liu, L. | | Deposit date: | 2023-03-18 | | Release date: | 2024-03-06 | | Method: | X-RAY DIFFRACTION (2.35 Å) | | Cite: | Structure of Mycobacterial ergothioneine-biosynthesis C-S lyase EgtE
To Be Published
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8J5Y
 | | Structural and mechanistic insight into ribosomal ITS2 RNA processing by nuclease-kinase machinery | | Descriptor: | LAS1 isoform 1, Polynucleotide 5'-hydroxyl-kinase GRC3 | | Authors: | Chen, J, Chen, H, Li, S, Lin, X, Hu, R, Zhang, K, Liu, L. | | Deposit date: | 2023-04-24 | | Release date: | 2024-01-17 | | Method: | ELECTRON MICROSCOPY (3.07 Å) | | Cite: | Structural and mechanistic insights into ribosomal ITS2 RNA processing by nuclease-kinase machinery.
Elife, 12, 2024
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8J60
 | | Structural and mechanistic insight into ribosomal ITS2 RNA processing by nuclease-kinase machinery | | Descriptor: | LAS1 protein, Polynucleotide 5'-hydroxyl-kinase GRC3 | | Authors: | Chen, J, Chen, H, Li, S, Lin, X, Hu, R, Zhang, K, Liu, L. | | Deposit date: | 2023-04-24 | | Release date: | 2024-01-17 | | Method: | ELECTRON MICROSCOPY (3.39 Å) | | Cite: | Structural and mechanistic insights into ribosomal ITS2 RNA processing by nuclease-kinase machinery.
Elife, 12, 2024
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7CU9
 | | Crystal structure of the soluble domain of TiME protein from Mycobacterium smegmatis | | Descriptor: | GLYCEROL, MAGNESIUM ION, Tube-forming protein in Mycobacterial Envelpe, ... | | Authors: | Gong, W, Cai, X, Liu, L, Wen, C. | | Deposit date: | 2020-08-21 | | Release date: | 2021-08-25 | | Last modified: | 2022-03-16 | | Method: | X-RAY DIFFRACTION (1.55 Å) | | Cite: | Identification and architecture of a putative secretion tube across mycobacterial outer envelope.
Sci Adv, 7, 2021
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7CU8
 | | Crystal structure of the soluble domain of TiME protein from Mycobacterium tuberculosis | | Descriptor: | SULFATE ION, Tube-forming protein in Mycobacterial Envelope (TiME) | | Authors: | Gong, W, Cai, X, Liu, L, Wen, C. | | Deposit date: | 2020-08-21 | | Release date: | 2021-08-25 | | Last modified: | 2023-11-29 | | Method: | X-RAY DIFFRACTION (3.3 Å) | | Cite: | Identification and architecture of a putative secretion tube across mycobacterial outer envelope.
Sci Adv, 7, 2021
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7DP3
 | | Human MCM8 N-terminal domain | | Descriptor: | DNA helicase MCM8, ZINC ION | | Authors: | Li, J, Liu, L, Liu, Y. | | Deposit date: | 2020-12-17 | | Release date: | 2021-05-19 | | Last modified: | 2023-11-29 | | Method: | X-RAY DIFFRACTION (2.55 Å) | | Cite: | Structural study of the N-terminal domain of human MCM8/9 complex.
Structure, 29, 2021
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7DPD
 | | Human MCM9 N-terminal domain | | Descriptor: | DNA helicase MCM9, SODIUM ION, ZINC ION | | Authors: | Li, J, Liu, L, Liu, Y. | | Deposit date: | 2020-12-18 | | Release date: | 2021-05-19 | | Last modified: | 2024-04-03 | | Method: | X-RAY DIFFRACTION (2.55 Å) | | Cite: | Structural study of the N-terminal domain of human MCM8/9 complex.
Structure, 29, 2021
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6IYA
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7XD7
 | | The pre-Tet-C state of wild-type Tetrahymena group I intron with 30nt 3'/5'-exon | | Descriptor: | MAGNESIUM ION, SPERMIDINE, The pre-Tet-C state molecule of co-transcriptional folded wild-type Tetrahymena group I intron with 30nt 3'/5'-exon | | Authors: | Luo, B, Zhang, C, Ling, X, Mukherjee, S, Jia, G, Xie, J, Jia, X, Liu, L, Baulin, E.F, Luo, Y, Jiang, L, Dong, H, Wei, X, Bujnicki, J.M, Su, Z. | | Deposit date: | 2022-03-26 | | Release date: | 2023-03-29 | | Method: | ELECTRON MICROSCOPY (3.02 Å) | | Cite: | Cryo-EM reveals dynamics of Tetrahymena group I intron self-splicing
Nat Catal, 2023
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7XD4
 | | The intermediate pre-Tet-S1 state of wild-type Tetrahymena group I intron with 6nt 3'/5'-exon | | Descriptor: | Co-transcriptional folded wild-type Tetrahymena group I intron with 6nt 3'/5'-exon, MAGNESIUM ION | | Authors: | Luo, B, Zhang, C, Ling, X, Mukherjee, S, Jia, G, Xie, J, Jia, X, Liu, L, Baulin, E.F, Luo, Y, Jiang, L, Dong, H, Wei, X, Bujnicki, J.M, Su, Z. | | Deposit date: | 2022-03-26 | | Release date: | 2023-03-29 | | Method: | ELECTRON MICROSCOPY (3.89 Å) | | Cite: | Cryo-EM reveals dynamics of Tetrahymena group I intron self-splicing
Nat Catal, 2023
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