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7C7B
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BU of 7c7b by Molmil
Crystal structure of human TRAP1 with SJT009
Descriptor: 2-azanyl-9-[(6-bromanyl-1,3-benzodioxol-5-yl)methyl]-6-chloranyl-purin-8-ol, Heat shock protein 75 kDa, mitochondrial
Authors:Kim, D, Yang, S, Yoon, N.G, Park, E, Kim, S.Y, Kang, B.H, Lee, C, Kang, S.
Deposit date:2020-05-24
Release date:2021-05-26
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Design and Synthesis of TRAP1 Selective Inhibitors: H-Bonding with Asn171 Residue in TRAP1 Increases Paralog Selectivity.
Acs Med.Chem.Lett., 12, 2021
7C7C
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BU of 7c7c by Molmil
Crystal structure of human TRAP1 with SJT104
Descriptor: 2-azanyl-9-[(4-bromanyl-2-fluoranyl-phenyl)methyl]-6-chloranyl-purin-8-ol, Heat shock protein 75 kDa, mitochondrial
Authors:Kim, D, Yang, S, Yoon, N.G, Park, E, Kim, S.Y, Kang, B.H, Lee, C, Kang, S.
Deposit date:2020-05-24
Release date:2021-05-26
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (3 Å)
Cite:Design and Synthesis of TRAP1 Selective Inhibitors: H-Bonding with Asn171 Residue in TRAP1 Increases Paralog Selectivity.
Acs Med.Chem.Lett., 12, 2021
1WKO
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BU of 1wko by Molmil
Terminal flower 1 (tfl1) from arabidopsis thaliana
Descriptor: TERMINAL FLOWER 1 protein
Authors:Miller, D, Banfield, M.J, Winter, V.J, Brady, R.L.
Deposit date:2004-06-01
Release date:2005-06-28
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:A divergent external loop confers antagonistic activity on floral regulators FT and TFL1.
Embo J., 25, 2006
1WKP
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BU of 1wkp by Molmil
Flowering locus t (ft) from arabidopsis thaliana
Descriptor: FLOWERING LOCUS T protein, SULFATE ION
Authors:Miller, D, Banfield, M.J, Winter, V.J, Brady, R.L.
Deposit date:2004-06-01
Release date:2005-06-28
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:A divergent external loop confers antagonistic activity on floral regulators FT and TFL1.
Embo J., 25, 2006
7BXZ
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BU of 7bxz by Molmil
Crystal structure of the aminoglycoside 6'-N-acetyltransferase from Enterococcus faecium
Descriptor: Aminoglycoside 6'-N-acetyltransferase
Authors:Kwon, S, Park, H.H.
Deposit date:2020-04-21
Release date:2020-08-12
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.502 Å)
Cite:Structural analysis of a novel substrate-free form of the aminoglycoside 6'-N-acetyltransferase from Enterococcus faecium.
Acta Crystallogr.,Sect.F, 76, 2020
4ES0
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BU of 4es0 by Molmil
X-ray structure of WDR5-SETd1b Win motif peptide binary complex
Descriptor: Histone-lysine N-methyltransferase SETD1B, WD repeat-containing protein 5
Authors:Dharmarajan, V, Lee, J.-H, Patel, A, Skalnik, D.G, Cosgrove, M.S.
Deposit date:2012-04-21
Release date:2012-05-30
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (1.817 Å)
Cite:Structural basis for WDR5 interaction (Win) motif recognition in human SET1 family histone methyltransferases.
J.Biol.Chem., 287, 2012
5XTF
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BU of 5xtf by Molmil
Crystal structure of the cis-dihydrodiol naphthalene dehydrogenase NahB from Pseudomonas sp. MC1
Descriptor: 2,3-dihydroxy-2,3-dihydrophenylpropionate dehydrogenase
Authors:Park, A.K, Kim, H.-W.
Deposit date:2017-06-19
Release date:2017-08-09
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.095 Å)
Cite:Crystal structure of cis-dihydrodiol naphthalene dehydrogenase (NahB) from Pseudomonas sp. MC1: Insights into the early binding process of the substrate
Biochem. Biophys. Res. Commun., 491, 2017
4ERZ
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BU of 4erz by Molmil
X-ray structure of WDR5-MLL4 Win motif peptide binary complex
Descriptor: Histone-lysine N-methyltransferase MLL4, WD repeat-containing protein 5
Authors:Dharmarajan, V, Lee, J.-H, Patel, A, Skalnik, D.G, Cosgrove, M.S.
Deposit date:2012-04-21
Release date:2012-05-30
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Structural basis for WDR5 interaction (Win) motif recognition in human SET1 family histone methyltransferases.
J.Biol.Chem., 287, 2012
4ERQ
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BU of 4erq by Molmil
X-ray structure of WDR5-MLL2 Win motif peptide binary complex
Descriptor: Histone-lysine N-methyltransferase MLL2, WD repeat-containing protein 5
Authors:Dharmarajan, V, Lee, J.-H, Patel, A, Skalnik, D.G, Cosgrove, M.S.
Deposit date:2012-04-20
Release date:2012-05-16
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (1.906 Å)
Cite:Structural basis for WDR5 interaction (Win) motif recognition in human SET1 family histone methyltransferases.
J.Biol.Chem., 287, 2012
5XTG
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BU of 5xtg by Molmil
Crystal structure of the cis-dihydrodiol naphthalene dehydrogenase NahB from Pseudomonas sp. MC1 in the presence of NAD+ and 2,3-dihydroxybiphenyl
Descriptor: 2,3-dihydroxy-2,3-dihydrophenylpropionate dehydrogenase, BIPHENYL-2,3-DIOL, CITRIC ACID, ...
Authors:Park, A.K, Kim, H.-W.
Deposit date:2017-06-19
Release date:2017-08-09
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.318 Å)
Cite:Crystal structure of cis-dihydrodiol naphthalene dehydrogenase (NahB) from Pseudomonas sp. MC1: Insights into the early binding process of the substrate
Biochem. Biophys. Res. Commun., 491, 2017
4B18
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BU of 4b18 by Molmil
The crystal structure of human Importin alpha 5 with TERT NLS peptide
Descriptor: IMPORTIN SUBUNIT ALPHA-1, TELOMERASE REVERSE TRANSCRIPTASE
Authors:Kim, K.L, Yoo, J.H, Cho, H.S.
Deposit date:2012-07-08
Release date:2013-09-04
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2.52 Å)
Cite:Akt-Mediated Phosphorylation Increases the Binding Affinity of Htert for Importin Alpha to Promote Nuclear Translocation.
J.Cell.Sci., 128, 2015
4ESG
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BU of 4esg by Molmil
X-ray structure of WDR5-MLL1 Win motif peptide binary complex
Descriptor: Histone-lysine N-methyltransferase MLL, WD repeat-containing protein 5
Authors:Dharmarajan, V, Lee, J.-H, Patel, A, Skalnik, D.G, Cosgrove, M.S.
Deposit date:2012-04-23
Release date:2012-05-30
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Structural basis for WDR5 interaction (Win) motif recognition in human SET1 family histone methyltransferases.
J.Biol.Chem., 287, 2012
4ERY
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BU of 4ery by Molmil
X-ray structure of WDR5-MLL3 Win motif peptide binary complex
Descriptor: Histone-lysine N-methyltransferase MLL3, WD repeat-containing protein 5
Authors:Dharmarajan, V, Lee, J.-H, Patel, A, Skalnik, D.G, Cosgrove, M.S.
Deposit date:2012-04-21
Release date:2012-05-16
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (1.3 Å)
Cite:Structural basis for WDR5 interaction (Win) motif recognition in human SET1 family histone methyltransferases.
J.Biol.Chem., 287, 2012
5ZXN
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BU of 5zxn by Molmil
Crystal structure of CurA from Vibrio vulnificus
Descriptor: 1,2-ETHANEDIOL, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, NADP-dependent oxidoreductase
Authors:Kim, M.-K, Bae, D.-W, Cha, S.-S.
Deposit date:2018-05-21
Release date:2019-04-03
Method:X-RAY DIFFRACTION (1.855 Å)
Cite:Structural and Biochemical Characterization of the Curcumin-Reducing Activity of CurA from Vibrio vulnificus.
J. Agric. Food Chem., 66, 2018
5ZXU
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BU of 5zxu by Molmil
Crystal structure of CurA in complex with NADPH from Vibrio vulnificus
Descriptor: NADP-dependent oxidoreductase, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
Authors:Kim, M.-K, Bae, D.-W, Cha, S.-S.
Deposit date:2018-05-21
Release date:2019-04-03
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structural and Biochemical Characterization of the Curcumin-Reducing Activity of CurA from Vibrio vulnificus.
J. Agric. Food Chem., 66, 2018
4EWR
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BU of 4ewr by Molmil
X-ray structure of WDR5-SETd1a Win motif peptide binary complex
Descriptor: Histone-lysine N-methyltransferase SETD1A, WD repeat-containing protein 5
Authors:Dharmarajan, V, Lee, J.-H, Patel, A, Skalnik, D.G, Cosgrove, M.S.
Deposit date:2012-04-27
Release date:2012-05-30
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (1.503 Å)
Cite:Structural basis for WDR5 interaction (Win) motif recognition in human SET1 family histone methyltransferases.
J.Biol.Chem., 287, 2012
2P7U
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BU of 2p7u by Molmil
The crystal structure of rhodesain, the major cysteine protease of T. brucei rhodesiense, bound to inhibitor K777
Descriptor: Cysteine protease, NALPHA-[(4-METHYLPIPERAZIN-1-YL)CARBONYL]-N-{(1S)-3-PHENYL-1-[2-(PHENYLSULFONYL)ETHYL]PROPYL}-L-PHENYLALANINAMIDE
Authors:Brinen, L.S, Marion, R.
Deposit date:2007-03-20
Release date:2008-03-25
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:Vinyl sulfones as antiparasitic agents and a structural basis for drug design.
J.Biol.Chem., 284, 2009
2OZ2
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BU of 2oz2 by Molmil
Crystal structure analysis of cruzain bound to vinyl sulfone derived inhibitor (K11777)
Descriptor: Cruzipain, NALPHA-[(4-METHYLPIPERAZIN-1-YL)CARBONYL]-N-{(1S)-3-PHENYL-1-[2-(PHENYLSULFONYL)ETHYL]PROPYL}-L-PHENYLALANINAMIDE, SULFATE ION
Authors:Rickert, M, Brinen, L.
Deposit date:2007-02-23
Release date:2008-02-26
Last modified:2019-09-04
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Vinyl sulfones as antiparasitic agents and a structural basis for drug design.
J.Biol.Chem., 284, 2009
7CPZ
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BU of 7cpz by Molmil
Crystal structure of Streptoavidin-C1 from Streptomyces cinamonensis
Descriptor: BIOTIN, Mature Streptoavidin-C1
Authors:Jeon, B.J, Kim, S, Lee, J.-H, Kim, M.S, Hwang, K.Y.
Deposit date:2020-08-08
Release date:2021-07-14
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Insights into the structure of mature streptavidin C1 from Streptomyces cinnamonensis reveal the self-binding of the extension C-terminal peptide to biotin-binding sites.
Iucrj, 8, 2021
7CQ0
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BU of 7cq0 by Molmil
Crystal structure of Streptoavidin-C1 from Streptomyces cinamonensis
Descriptor: Mature Streptoavidin-C1
Authors:Jeon, B.J, Kim, S, Lee, J.-H, Kim, M.S, Hwang, K.Y.
Deposit date:2020-08-08
Release date:2021-07-14
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.03 Å)
Cite:Insights into the structure of mature streptavidin C1 from Streptomyces cinnamonensis reveal the self-binding of the extension C-terminal peptide to biotin-binding sites.
Iucrj, 8, 2021
7YC5
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BU of 7yc5 by Molmil
Cryo-EM structure of SARS-CoV-2 spike in complex with K202.B bispecific antibody
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Heavy chain from K202.B, bispecific antibody, ...
Authors:Yoo, Y, Cho, H.S.
Deposit date:2022-06-30
Release date:2023-07-05
Last modified:2024-05-08
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:Novel bispecific human antibody platform specifically targeting a fully open spike conformation potently neutralizes multiple SARS-CoV-2 variants.
Antiviral Res., 212, 2023
6JKW
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BU of 6jkw by Molmil
Seleno-methionine PNGM-1 from deep-sea sediment metagenome
Descriptor: Metallo-beta-lactamases PNGM-1, ZINC ION
Authors:Hong, M.K, Park, K.S, Jeon, J.H, Lee, J.H, Park, Y.S, Lee, S.H, Kang, L.W.
Deposit date:2019-03-02
Release date:2019-04-17
Method:X-RAY DIFFRACTION (2.29 Å)
Cite:PNGM 1 a novel subclass B3 metallo beta lactamase from a deep sea sediment metagenome
Journal of Global Antimicrobial Resistance, 14, 2018
1JO7
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BU of 1jo7 by Molmil
Solution Structure of Influenza A Virus Promoter
Descriptor: Influenza A virus promoter RNA
Authors:Bae, S.-H, Cheong, H.-K, Lee, J.-H, Cheong, C, Kainosho, M, Choi, B.-S.
Deposit date:2001-07-27
Release date:2001-09-19
Last modified:2024-05-22
Method:SOLUTION NMR
Cite:Structural features of an influenza virus promoter and their implications for viral RNA synthesis.
Proc.Natl.Acad.Sci.USA, 98, 2001
4TOY
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BU of 4toy by Molmil
Structure of 35O22 Fab, a HIV-1 neutralizing antibody
Descriptor: 35O22 Fab Heavy chain, 35O22 Fab Light chain
Authors:Pancera, M, Kwong, P.D.
Deposit date:2014-06-06
Release date:2014-09-03
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.551 Å)
Cite:Broad and potent HIV-1 neutralization by a human antibody that binds the gp41-gp120 interface.
Nature, 515, 2014
4UC4
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BU of 4uc4 by Molmil
Crystal structure of hybrid tudor domain of human lysine demethylase KDM4B
Descriptor: Lysine-specific demethylase 4B
Authors:Wang, F, Su, Z, Denu, J.M, Phillips Jr, G.N.
Deposit date:2014-08-13
Release date:2016-03-16
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.5612 Å)
Cite:Reader domain specificity and lysine demethylase-4 family function.
Nat Commun, 7, 2016

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数据于2024-07-17公开中

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