5X93
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![BU of 5x93 by Molmil](/molmil-images/mine/5x93) | Human endothelin receptor type-B in complex with antagonist K-8794 | Descriptor: | (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, 3-[6-[(4-tert-butylphenyl)sulfonylamino]-5-(2-methoxyphenoxy)-2-pyrimidin-2-yl-pyrimidin-4-yl]oxy-N-(2,6-dimethylphenyl)propanamide, CHOLESTEROL, ... | Authors: | Shihoya, W, Nishizawa, T, Yamashita, K, Hirata, K, Okuta, A, Tani, K, Fujiyoshi, Y, Doi, T, Nureki, O. | Deposit date: | 2017-03-05 | Release date: | 2017-08-16 | Last modified: | 2017-11-15 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | X-ray structures of endothelin ETB receptor bound to clinical antagonist bosentan and its analog Nat. Struct. Mol. Biol., 24, 2017
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6K7H
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![BU of 6k7h by Molmil](/molmil-images/mine/6k7h) | Cryo-EM structure of the human P4-type flippase ATP8A1-CDC50 (E1 state class2) | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CHOLESTEROL HEMISUCCINATE, Cell cycle control protein 50A, ... | Authors: | Hiraizumi, M, Yamashita, K, Nishizawa, T, Nureki, O. | Deposit date: | 2019-06-07 | Release date: | 2019-08-28 | Last modified: | 2021-02-10 | Method: | ELECTRON MICROSCOPY (3.22 Å) | Cite: | Cryo-EM structures capture the transport cycle of the P4-ATPase flippase. Science, 365, 2019
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6K7I
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![BU of 6k7i by Molmil](/molmil-images/mine/6k7i) | Cryo-EM structure of the human P4-type flippase ATP8A1-CDC50 (E1-ATP state class2) | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CHOLESTEROL HEMISUCCINATE, Cell cycle control protein 50A, ... | Authors: | Hiraizumi, M, Yamashita, K, Nishizawa, T, Nureki, O. | Deposit date: | 2019-06-07 | Release date: | 2019-08-28 | Last modified: | 2021-02-10 | Method: | ELECTRON MICROSCOPY (3.22 Å) | Cite: | Cryo-EM structures capture the transport cycle of the P4-ATPase flippase. Science, 365, 2019
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6K7N
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![BU of 6k7n by Molmil](/molmil-images/mine/6k7n) | Cryo-EM structure of the human P4-type flippase ATP8A1-CDC50 (E1P state) | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CHOLESTEROL HEMISUCCINATE, Cell cycle control protein 50A, ... | Authors: | Hiraizumi, M, Yamashita, K, Nishizawa, T, Nureki, O. | Deposit date: | 2019-06-07 | Release date: | 2019-08-28 | Last modified: | 2021-02-10 | Method: | ELECTRON MICROSCOPY (2.84 Å) | Cite: | Cryo-EM structures capture the transport cycle of the P4-ATPase flippase. Science, 365, 2019
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6K7J
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![BU of 6k7j by Molmil](/molmil-images/mine/6k7j) | Cryo-EM structure of the human P4-type flippase ATP8A1-CDC50 (E1-ATP state class1) | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CHOLESTEROL HEMISUCCINATE, Cell cycle control protein 50A, ... | Authors: | Hiraizumi, M, Yamashita, K, Nishizawa, T, Nureki, O. | Deposit date: | 2019-06-07 | Release date: | 2019-08-28 | Last modified: | 2021-02-10 | Method: | ELECTRON MICROSCOPY (3.08 Å) | Cite: | Cryo-EM structures capture the transport cycle of the P4-ATPase flippase. Science, 365, 2019
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7DEH
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![BU of 7deh by Molmil](/molmil-images/mine/7deh) | |
6K7K
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![BU of 6k7k by Molmil](/molmil-images/mine/6k7k) | Cryo-EM structure of the human P4-type flippase ATP8A1-CDC50 (E1-ADP-Pi state) | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, ADENOSINE-5'-DIPHOSPHATE, CHOLESTEROL HEMISUCCINATE, ... | Authors: | Hiraizumi, M, Yamashita, K, Nishizawa, T, Nureki, O. | Deposit date: | 2019-06-07 | Release date: | 2019-08-28 | Last modified: | 2021-02-10 | Method: | ELECTRON MICROSCOPY (3.04 Å) | Cite: | Cryo-EM structures capture the transport cycle of the P4-ATPase flippase. Science, 365, 2019
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7DB6
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![BU of 7db6 by Molmil](/molmil-images/mine/7db6) | human melatonin receptor MT1 - Gi1 complex | Descriptor: | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(i) subunit alpha-1, ... | Authors: | Okamoto, H.H, Kusakizako, T, Shihioya, W, Yamashita, K, Nishizawa, T, Nureki, O. | Deposit date: | 2020-10-19 | Release date: | 2021-08-18 | Last modified: | 2022-02-16 | Method: | ELECTRON MICROSCOPY (3.3 Å) | Cite: | Cryo-EM structure of the human MT 1 -G i signaling complex. Nat.Struct.Mol.Biol., 28, 2021
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2YS4
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![BU of 2ys4 by Molmil](/molmil-images/mine/2ys4) | Solution structure of the N-terminal PapD-like domain of HYDIN protein from human | Descriptor: | Hydrocephalus-inducing protein homolog | Authors: | Li, H, Tomizawa, T, Koshiba, S, Watanabe, S, Harada, T, Kigawa, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | Deposit date: | 2007-04-03 | Release date: | 2008-04-08 | Last modified: | 2024-05-29 | Method: | SOLUTION NMR | Cite: | Solution structure of the N-terminal PapD-like domain of HYDIN protein from human To be Published
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2YS9
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![BU of 2ys9 by Molmil](/molmil-images/mine/2ys9) | structure of the third Homeodomain from the human homeobox and leucine zipper protein, Homez | Descriptor: | Homeobox and leucine zipper protein Homez | Authors: | Ohnishi, S, Tomizawa, T, Koshiba, S, Harada, T, Watanabe, S, Kigawa, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | Deposit date: | 2007-04-03 | Release date: | 2007-10-09 | Last modified: | 2024-05-29 | Method: | SOLUTION NMR | Cite: | structure of the third Homeodomain from the human homeobox and leucine zipper protein, Homez To be Published
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2YTV
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![BU of 2ytv by Molmil](/molmil-images/mine/2ytv) | Solution structure of the fifth cold-shock domain of the human KIAA0885 protein (unr protein) | Descriptor: | Cold shock domain-containing protein E1 | Authors: | Goroncy, A.K, Tochio, N, Tomizawa, T, Koshiba, S, Watanabe, S, Harada, T, Kigawa, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | Deposit date: | 2007-04-05 | Release date: | 2008-04-08 | Last modified: | 2024-05-01 | Method: | SOLUTION NMR | Cite: | The NMR solution structures of the five constituent cold-shock domains (CSD) of the human UNR (upstream of N-ras) protein. J.Struct.Funct.Genom., 11, 2010
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7C7L
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![BU of 7c7l by Molmil](/molmil-images/mine/7c7l) | Cryo-EM structure of the Cas12f1-sgRNA-target DNA complex | Descriptor: | CRISPR-associated protein Cas14a.1, DNA (40-mer), ZINC ION, ... | Authors: | Takeda, N.S, Nakagawa, R, Okazaki, S, Hirano, H, Kobayashi, K, Kusakizako, T, Nishizawa, T, Yamashita, K, Nishimasu, H, Nureki, O. | Deposit date: | 2020-05-26 | Release date: | 2020-12-23 | Last modified: | 2024-03-27 | Method: | ELECTRON MICROSCOPY (3.3 Å) | Cite: | Structure of the miniature type V-F CRISPR-Cas effector enzyme. Mol.Cell, 81, 2021
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2ZAJ
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![BU of 2zaj by Molmil](/molmil-images/mine/2zaj) | Solution structure of the short-isoform of the second WW domain from the human membrane-associated guanylate kinase, WW and PDZ domain-containing protein 1 (MAGI-1) | Descriptor: | Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 1 | Authors: | Ohnishi, S, Tochio, N, Tomizawa, T, Koshiba, S, Harada, T, Watanabe, S, Kigawa, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | Deposit date: | 2007-10-05 | Release date: | 2008-04-15 | Last modified: | 2024-05-29 | Method: | SOLUTION NMR | Cite: | Solution structure of the short-isoform of the second WW domain from the human membrane-associated guanylate kinase, WW and PDZ domain-containing protein 1 (MAGI-1) To be Published
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7E8D
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![BU of 7e8d by Molmil](/molmil-images/mine/7e8d) | NSD2 E1099K mutant bound to nucleosome | Descriptor: | DNA (185-MER), Histone H2A type 1, Histone H2B type 1-J, ... | Authors: | Sengoku, T, Sato, K, Nishizawa, T, Nureki, O, Ogata, K. | Deposit date: | 2021-03-01 | Release date: | 2021-11-10 | Last modified: | 2024-06-05 | Method: | ELECTRON MICROSCOPY (2.8 Å) | Cite: | Structural basis of the regulation of the normal and oncogenic methylation of nucleosomal histone H3 Lys36 by NSD2. Nat Commun, 12, 2021
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2YUR
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![BU of 2yur by Molmil](/molmil-images/mine/2yur) | Solution structure of the Ring finger of human Retinoblastoma-binding protein 6 | Descriptor: | Retinoblastoma-binding protein 6, ZINC ION | Authors: | Abe, H, Miyamoto, K, Tochio, N, Tomizawa, T, Koshiba, S, Harada, T, Watanabe, S, Kigawa, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | Deposit date: | 2007-04-06 | Release date: | 2008-04-08 | Last modified: | 2024-05-29 | Method: | SOLUTION NMR | Cite: | Solution structure of the Ring finger of human Retinoblastoma-binding protein 6 To be Published
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1IRR
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![BU of 1irr by Molmil](/molmil-images/mine/1irr) | Solution structure of paralytic peptide of the silkworm, Bombyx mori | Descriptor: | paralytic peptide | Authors: | Miura, K, Kamimura, M, Aizawa, T, Kiuchi, M, Hayakawa, Y, Mizuguchi, M, Kawano, K. | Deposit date: | 2001-10-23 | Release date: | 2003-02-11 | Last modified: | 2023-12-27 | Method: | SOLUTION NMR | Cite: | Solution structure of paralytic peptide of silkworm, Bombyx mori peptides, 23, 2002
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1IP0
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![BU of 1ip0 by Molmil](/molmil-images/mine/1ip0) | NMR STRUCTURE OF HUMAN BETACELLULIN-2 | Descriptor: | BETACELLULIN | Authors: | Miura, K, Doura, H, Aizawa, T, Tada, H, Seno, M, Yamada, H, Kawano, K. | Deposit date: | 2001-04-19 | Release date: | 2002-07-31 | Last modified: | 2023-12-27 | Method: | SOLUTION NMR | Cite: | Solution structure of betacellulin, a new member of EGF-family ligands. Biochem.Biophys.Res.Commun., 294, 2002
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1IOX
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![BU of 1iox by Molmil](/molmil-images/mine/1iox) | NMR Structure of human Betacellulin-2 | Descriptor: | Betacellulin | Authors: | Miura, K, Doura, H, Aizawa, T, Tada, H, Seno, M, Yamada, H, Kawano, K. | Deposit date: | 2001-04-18 | Release date: | 2002-07-24 | Last modified: | 2023-12-27 | Method: | SOLUTION NMR | Cite: | Solution structure of betacellulin, a new member of EGF-family ligands. Biochem.Biophys.Res.Commun., 294, 2002
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2YTX
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![BU of 2ytx by Molmil](/molmil-images/mine/2ytx) | Solution structure of the second cold-shock domain of the human KIAA0885 protein (UNR protein) | Descriptor: | Cold shock domain-containing protein E1 | Authors: | Goroncy, A.K, Tomizawa, T, Koshiba, S, Inoue, M, Kigawa, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | Deposit date: | 2007-04-05 | Release date: | 2008-04-08 | Last modified: | 2024-05-01 | Method: | SOLUTION NMR | Cite: | The NMR solution structures of the five constituent cold-shock domains (CSD) of the human UNR (upstream of N-ras) protein. J.Struct.Funct.Genom., 11, 2010
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2YTO
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![BU of 2yto by Molmil](/molmil-images/mine/2yto) | Solution structure of the C2H2 type zinc finger (region 659-691) of human Zinc finger protein 484 | Descriptor: | ZINC ION, Zinc finger protein 484 | Authors: | Tochio, N, Tomizawa, T, Abe, H, Saito, K, Li, H, Sato, M, Koshiba, S, Kobayashi, N, Kigawa, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | Deposit date: | 2007-04-05 | Release date: | 2007-10-09 | Last modified: | 2024-05-29 | Method: | SOLUTION NMR | Cite: | Solution structure of the C2H2 type zinc finger (region 659-691) of human Zinc finger protein 484 To be Published
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2YTP
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![BU of 2ytp by Molmil](/molmil-images/mine/2ytp) | Solution structure of the C2H2 type zinc finger (region 687-719) of human Zinc finger protein 484 | Descriptor: | ZINC ION, Zinc finger protein 484 | Authors: | Tochio, N, Tomizawa, T, Abe, H, Saito, K, Li, H, Sato, M, Koshiba, S, Kobayashi, N, Kigawa, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | Deposit date: | 2007-04-05 | Release date: | 2007-10-09 | Last modified: | 2024-05-29 | Method: | SOLUTION NMR | Cite: | Solution structure of the C2H2 type zinc finger (region 687-719) of human Zinc finger protein 484 To be Published
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2YTM
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![BU of 2ytm by Molmil](/molmil-images/mine/2ytm) | Solution structure of the C2H2 type zinc finger (region 696-728) of human Zinc finger protein 28 homolog | Descriptor: | ZINC ION, Zinc finger protein 28 homolog | Authors: | Tochio, N, Tomizawa, T, Abe, H, Saito, K, Li, H, Sato, M, Koshiba, S, Kobayashi, N, Kigawa, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | Deposit date: | 2007-04-05 | Release date: | 2007-10-09 | Last modified: | 2024-05-29 | Method: | SOLUTION NMR | Cite: | Solution structure of the C2H2 type zinc finger (region 696-728) of human Zinc finger protein 28 homolog To be Published
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2YS2
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![BU of 2ys2 by Molmil](/molmil-images/mine/2ys2) | Solution structure of the BTK motif of human Cytoplasmic tyrosine-protein kinase BMX | Descriptor: | Cytoplasmic tyrosine-protein kinase BMX, ZINC ION | Authors: | Abe, H, Tochio, N, Tomizawa, T, Koshiba, S, Yoneyama, M, Inoue, M, Kigawa, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | Deposit date: | 2007-04-03 | Release date: | 2007-10-09 | Last modified: | 2024-05-29 | Method: | SOLUTION NMR | Cite: | Solution structure of the BTK motif of human Cytoplasmic tyrosine-protein kinase BMX To be Published
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2YTN
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![BU of 2ytn by Molmil](/molmil-images/mine/2ytn) | Solution structure of the C2H2 type zinc finger (region 732-764) of human Zinc finger protein 347 | Descriptor: | ZINC ION, Zinc finger protein 347 | Authors: | Tochio, N, Tomizawa, T, Abe, H, Saito, K, Li, H, Sato, M, Koshiba, S, Kobayashi, N, Kigawa, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | Deposit date: | 2007-04-05 | Release date: | 2007-10-09 | Last modified: | 2024-05-29 | Method: | SOLUTION NMR | Cite: | Solution structure of the C2H2 type zinc finger (region 732-764) of human Zinc finger protein 347 To be Published
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2YUJ
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![BU of 2yuj by Molmil](/molmil-images/mine/2yuj) | |