6K7I
Cryo-EM structure of the human P4-type flippase ATP8A1-CDC50 (E1-ATP state class2)
Summary for 6K7I
Entry DOI | 10.2210/pdb6k7i/pdb |
EMDB information | 9934 |
Descriptor | Phospholipid-transporting ATPase, Cell cycle control protein 50A, alpha-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (6 entities in total) |
Functional Keywords | flippase, membrane protein |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 2 |
Total formula weight | 173286.27 |
Authors | Hiraizumi, M.,Yamashita, K.,Nishizawa, T.,Nureki, O. (deposition date: 2019-06-07, release date: 2019-08-28, Last modification date: 2021-02-10) |
Primary citation | Hiraizumi, M.,Yamashita, K.,Nishizawa, T.,Nureki, O. Cryo-EM structures capture the transport cycle of the P4-ATPase flippase. Science, 365:1149-1155, 2019 Cited by PubMed: 31416931DOI: 10.1126/science.aay3353 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (3.22 Å) |
Structure validation
Download full validation report