1TKD
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![BU of 1tkd by Molmil](/molmil-images/mine/1tkd) | T7 DNA polymerase ternary complex with 8 oxo guanosine and dCMP at the elongation site | Descriptor: | 2',3'-DIDEOXY-THYMIDINE-5'-TRIPHOSPHATE, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, DNA (5'-D(*CP*CP*CP*AP*(8OG)P*TP*GP*GP*CP*AP*CP*TP*GP*GP*CP*CP*GP*TP*CP*GP*TP*TP*TP*TP*CP*G)-3'), ... | Authors: | Brieba, L.G, Eichman, B.F, Kokoska, R.J, Doublie, S, Kunkel, T.A, Ellenberger, T. | Deposit date: | 2004-06-08 | Release date: | 2004-08-31 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (2.49 Å) | Cite: | Structural basis for the dual coding potential of 8-oxoguanosine by a high-fidelity DNA polymerase. Embo J., 23, 2004
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1Q57
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![BU of 1q57 by Molmil](/molmil-images/mine/1q57) | The Crystal Structure of the Bifunctional Primase-Helicase of Bacteriophage T7 | Descriptor: | DNA primase/helicase | Authors: | Toth, E.A, Li, Y, Sawaya, M.R, Cheng, Y, Ellenberger, T. | Deposit date: | 2003-08-06 | Release date: | 2003-11-25 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (3.45 Å) | Cite: | The Crystal Structure of the Bifunctional Primase-Helicase of Bacteriophage T7 Mol.Cell, 12, 2003
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1TK8
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![BU of 1tk8 by Molmil](/molmil-images/mine/1tk8) | T7 DNA polymerase ternary complex with 8 oxo guanosine and dAMP at the elongation site | Descriptor: | 2',3'-DIDEOXY-THYMIDINE-5'-TRIPHOSPHATE, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, 5'-D(*CP*CP*CP*AP*(8OG)P*TP*GP*GP*CP*AP*CP*TP*GP*GP*CP*CP*GP*TP*CP*GP*TP*TP*TP*TP*CP*G)-3', ... | Authors: | Brieba, L.G, Eichman, B.F, Kokoska, R.J, Doublie, S, Kunkel, T.A, Ellenberger, T. | Deposit date: | 2004-06-08 | Release date: | 2004-08-31 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Structural basis for the dual coding potential of 8-oxoguanosine by a high-fidelity DNA polymerase. Embo J., 23, 2004
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1TK5
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![BU of 1tk5 by Molmil](/molmil-images/mine/1tk5) | T7 DNA polymerase binary complex with 8 oxo guanosine in the templating strand | Descriptor: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, 5'-D(*CP*CP*CP*(8OG)P*CP*TP*GP*GP*CP*AP*CP*TP*GP*GP*CP*CP*GP*TP*CP*GP*TP*TP*TP*TP*CP*G)-3', 5'-D(*CP*GP*AP*AP*A*GP*CP*CP*AP*GP*TP*GP*CP*CP*AP*(DDG)P*TP*GP*CP*AP*A)-3', ... | Authors: | Brieba, L.G, Eichman, B.F, Kokoska, R.J, Doublie, S, Kunkel, T.A, Ellenberger, T. | Deposit date: | 2004-06-08 | Release date: | 2004-08-31 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Structural basis for the dual coding potential of 8-oxoguanosine by a high-fidelity DNA polymerase. Embo J., 23, 2004
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1TK0
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![BU of 1tk0 by Molmil](/molmil-images/mine/1tk0) | T7 DNA polymerase ternary complex with 8 oxo guanosine and ddCTP at the insertion site | Descriptor: | 2',3'-DIDEOXYCYTIDINE 5'-TRIPHOSPHATE, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, 5'-D(*CP*CP*CP*(8OG)P*CP*TP*GP*GP*CP*AP*CP*TP*GP*GP*CP*CP*GP*TP*CP*GP*TP*TP*TP*TP*CP*G)-3', ... | Authors: | Brieba, L.G, Eichman, B.F, Kokoska, R.J, Doublie, S, Kunkel, T.A, Ellenberger, T. | Deposit date: | 2004-06-07 | Release date: | 2004-08-31 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Structural basis for the dual coding potential of 8-oxoguanosine by a high-fidelity DNA polymerase. Embo J., 23, 2004
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2Z39
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![BU of 2z39 by Molmil](/molmil-images/mine/2z39) | |
1T7P
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![BU of 1t7p by Molmil](/molmil-images/mine/1t7p) | T7 DNA POLYMERASE COMPLEXED TO DNA PRIMER/TEMPLATE,A NUCLEOSIDE TRIPHOSPHATE, AND ITS PROCESSIVITY FACTOR THIOREDOXIN | Descriptor: | 2'-3'-DIDEOXYGUANOSINE-5'-TRIPHOSPHATE, DNA (5'-D(P*CP*CP*TP*TP*GP*GP*CP*AP*CP*TP*GP*GP*C)-3'), DNA (5'-D(P*GP*CP*CP*AP*GP*TP*GP*CP*CP*AP*2DA)-3'), ... | Authors: | Doublie, S, Tabor, S, Long, A.M, Richardson, C.C, Ellenberger, T. | Deposit date: | 1997-09-24 | Release date: | 1998-02-25 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Crystal structure of a bacteriophage T7 DNA replication complex at 2.2 A resolution. Nature, 391, 1998
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4BFY
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![BU of 4bfy by Molmil](/molmil-images/mine/4bfy) | |
4BFV
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![BU of 4bfv by Molmil](/molmil-images/mine/4bfv) | Crystal structure of Mycobacterium tuberculosis PanK in complex with a triazole inhibitory compound (1d) and phosphate | Descriptor: | N-[1-(4-methyl-5-{[2-(2-methylphenoxy)ethyl]sulfanyl}-4H-1,2,4-triazol-3-yl)ethyl]-2-(trifluoromethyl)benzamide, PANTOTHENATE KINASE, PHOSPHATE ION | Authors: | Bjorkelid, C, Bergfors, T, Jones, T.A. | Deposit date: | 2013-03-22 | Release date: | 2013-05-15 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2.29 Å) | Cite: | Structural and Biochemical Characterization of Compounds Inhibiting Mycobacterium Tuberculosis Pank J.Biol.Chem., 288, 2013
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4BFZ
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![BU of 4bfz by Molmil](/molmil-images/mine/4bfz) | |
4BMF
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![BU of 4bmf by Molmil](/molmil-images/mine/4bmf) | |
1BNK
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![BU of 1bnk by Molmil](/molmil-images/mine/1bnk) | HUMAN 3-METHYLADENINE DNA GLYCOSYLASE COMPLEXED TO DNA | Descriptor: | DNA (5'-D(*GP*AP*CP*AP*TP*GP*YRRP*TP*TP*GP*CP*CP*T)-3'), DNA (5'-D(*GP*GP*CP*AP*AP*TP*CP*AP*TP*GP*TP*CP*A)-3'), PROTEIN (3-METHYLADENINE DNA GLYCOSYLASE) | Authors: | Lau, A.Y, Schaerer, O.D, Samson, L, Verdine, G.L, Ellenberger, T. | Deposit date: | 1998-07-29 | Release date: | 1998-10-21 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Crystal structure of a human alkylbase-DNA repair enzyme complexed to DNA: mechanisms for nucleotide flipping and base excision. Cell(Cambridge,Mass.), 95, 1998
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1CR4
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![BU of 1cr4 by Molmil](/molmil-images/mine/1cr4) | CRYSTAL STRUCTURE OF THE HELICASE DOMAIN OF THE GENE 4 PROTEIN OF BACTERIOPHAGE T7: COMPLEX WITH DTDP | Descriptor: | DNA PRIMASE/HELICASE, SULFATE ION, THYMIDINE-5'-DIPHOSPHATE | Authors: | Sawaya, M.R, Guo, S, Tabor, S, Richardson, C.C, Ellenberger, T. | Deposit date: | 1999-08-12 | Release date: | 1999-11-10 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Crystal structure of the helicase domain from the replicative helicase-primase of bacteriophage T7. Cell(Cambridge,Mass.), 99, 1999
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4BFS
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![BU of 4bfs by Molmil](/molmil-images/mine/4bfs) | Crystal structure of Mycobacterium tuberculosis PanK in complex with a triazole inhibitory compound (1a) | Descriptor: | N-[1-(5-{[2-(4-FLUOROPHENOXY)ETHYL]SULFANYL}-4-METHYL-4H-1,2,4-TRIAZOL-3-YL)ETHYL]-2-(TRIFLUOROMETHYL)BENZAMIDE, PANTOTHENATE KINASE | Authors: | Bjorkelid, C, Bergfors, T, Jones, T.A. | Deposit date: | 2013-03-22 | Release date: | 2013-05-15 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | Structural and Biochemical Characterization of Compounds Inhibiting Mycobacterium Tuberculosis Pank J.Biol.Chem., 288, 2013
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1CR2
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![BU of 1cr2 by Molmil](/molmil-images/mine/1cr2) | CRYSTAL STRUCTURE OF THE HELICASE DOMAIN OF THE GENE 4 PROTEIN OF BACTERIOPHAGE T7: COMPLEX WITH DATP | Descriptor: | 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, DNA PRIMASE/HELICASE, SULFATE ION | Authors: | Sawaya, M.R, Guo, S, Tabor, S, Richardson, C.C, Ellenberger, T. | Deposit date: | 1999-08-12 | Release date: | 1999-11-10 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Crystal structure of the helicase domain from the replicative helicase-primase of bacteriophage T7. Cell(Cambridge,Mass.), 99, 1999
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1HB8
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![BU of 1hb8 by Molmil](/molmil-images/mine/1hb8) | Structure of bovine Acyl-CoA binding protein in tetragonal crystal form | Descriptor: | ACYL-COA BINDING PROTEIN, SULFATE ION | Authors: | Zou, J.Y, Kleywegt, G.J, Bergfors, T, Knudsen, J, Jones, T.A. | Deposit date: | 2001-04-12 | Release date: | 2002-03-11 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Binding Site Differences Revealed by Crystal Structures of Plasmodium Falciparum and Bovine Acyl-Coa Binding Protein J.Mol.Biol., 309, 2001
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1HB6
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![BU of 1hb6 by Molmil](/molmil-images/mine/1hb6) | Structure of bovine Acyl-CoA binding protein in orthorhombic crystal form | Descriptor: | ACYL-COA BINDING PROTEIN, CADMIUM ION | Authors: | Zou, J.Y, Kleywegt, G.J, Bergfors, T, Knudsen, J, Jones, T.A. | Deposit date: | 2001-04-12 | Release date: | 2002-03-11 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Binding Site Differences Revealed by Crystal Structures of Plasmodium Falciparum and Bovine Acyl-Coa Binding Protein J.Mol.Biol., 309, 2001
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1BOD
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![BU of 1bod by Molmil](/molmil-images/mine/1bod) | THE SOLUTION STRUCTURES OF MUTANT CALBINDIN D9K'S, AS DETERMINED BY NMR, SHOW THAT THE CALCIUM BINDING SITE CAN ADOPT DIFFERENT FOLDS | Descriptor: | CALBINDIN D9K | Authors: | Johansson, C, Ullner, M, Drakenberg, T. | Deposit date: | 1993-04-23 | Release date: | 1993-10-31 | Last modified: | 2024-04-10 | Method: | SOLUTION NMR | Cite: | The solution structures of mutant calbindin D9k's, as determined by NMR, show that the calcium-binding site can adopt different folds. Biochemistry, 32, 1993
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1CR1
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![BU of 1cr1 by Molmil](/molmil-images/mine/1cr1) | CRYSTAL STRUCTURE OF THE HELICASE DOMAIN OF THE GENE 4 PROTEIN OF BACTERIOPHAGE T7: COMPLEX WITH DTTP | Descriptor: | DNA PRIMASE/HELICASE, SULFATE ION, THYMIDINE-5'-TRIPHOSPHATE | Authors: | Sawaya, M.R, Guo, S, Tabor, S, Richardson, C.C, Ellenberger, T. | Deposit date: | 1999-08-12 | Release date: | 1999-11-10 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Crystal structure of the helicase domain from the replicative helicase-primase of bacteriophage T7. Cell(Cambridge,Mass.), 99, 1999
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1E0J
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![BU of 1e0j by Molmil](/molmil-images/mine/1e0j) | gp4d helicase from phage T7 ADPNP complex | Descriptor: | DNA HELICASE, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER | Authors: | Singleton, M.R, Sawaya, M.R, Ellenberger, T, Wigley, D.B. | Deposit date: | 2000-03-30 | Release date: | 2000-06-09 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Crystal Structure of T7 Gene 4 Ring Helicase Indicates a Mechanism for Sequential Hydrolysis of Nucleotides Cell(Cambridge,Mass.), 101, 2000
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1D5Y
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![BU of 1d5y by Molmil](/molmil-images/mine/1d5y) | CRYSTAL STRUCTURE OF THE E. COLI ROB TRANSCRIPTION FACTOR IN COMPLEX WITH DNA | Descriptor: | DNA (5'-D(*AP*CP*TP*TP*TP*GP*AP*CP*AP*TP*TP*CP*AP*GP*TP*GP*CP*TP*GP*TP*C)-3'), DNA (5'-D(*TP*GP*AP*CP*AP*GP*CP*AP*CP*TP*GP*AP*AP*TP*GP*TP*CP*AP*AP*AP*G)-3'), ROB TRANSCRIPTION FACTOR | Authors: | Kwon, H.J, Bennik, M.H.J, Demple, B, Ellenberger, T. | Deposit date: | 1999-10-12 | Release date: | 2000-04-24 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Crystal structure of the Escherichia coli Rob transcription factor in complex with DNA. Nat.Struct.Biol., 7, 2000
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7A8P
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![BU of 7a8p by Molmil](/molmil-images/mine/7a8p) | Structure of human mitochondrial RNA polymerase in complex with IMT inhibitor. | Descriptor: | (3~{R})-1-[(2~{R})-2-[4-(2-chloranyl-4-fluoranyl-phenyl)-2-oxidanylidene-chromen-7-yl]oxypropanoyl]piperidine-3-carboxylic acid, DNA-directed RNA polymerase, mitochondrial | Authors: | Hillen, H.S, Bonekamp, N, Peter, B, Felser, A, Bergbrede, T, Choidas, A, Horn, M, Unger, A, di Lucrezia, R, Atanassov, I, Li, X, Koch, U, Menninger, S, Boros, J, Habenberger, P, Giavalisco, P, Cramer, P, Denzel, M, Nussbaumer, P, Klebl, B, Falkenberg, M, Gustafsson, C.M, Larsson, N.G. | Deposit date: | 2020-08-30 | Release date: | 2020-12-30 | Last modified: | 2024-05-01 | Method: | ELECTRON MICROSCOPY (3.5 Å) | Cite: | Small-molecule inhibitors of human mitochondrial DNA transcription. Nature, 588, 2020
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1CR0
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![BU of 1cr0 by Molmil](/molmil-images/mine/1cr0) | CRYSTAL STRUCTURE OF THE HELICASE DOMAIN OF THE GENE4 PROTEIN OF BACTERIOPHAGE T7 | Descriptor: | DNA PRIMASE/HELICASE, SULFATE ION | Authors: | Sawaya, M.R, Guo, S, Tabor, S, Richardson, C.C, Ellenberger, T. | Deposit date: | 1999-08-12 | Release date: | 1999-11-10 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Crystal structure of the helicase domain from the replicative helicase-primase of bacteriophage T7. Cell(Cambridge,Mass.), 99, 1999
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4BFU
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![BU of 4bfu by Molmil](/molmil-images/mine/4bfu) | Crystal structure of Mycobacterium tuberculosis PanK in complex with a triazole inhibitory compound (1c) and phosphate | Descriptor: | N-[1-(5-{[(4-fluorophenyl)methyl]sulfanyl}-4-methyl-4H-1,2,4-triazol-3-yl)ethyl]-2-(trifluoromethyl)benzamide, PANTOTHENATE KINASE, PHOSPHATE ION | Authors: | Bjorkelid, C, Bergfors, T, Jones, T.A. | Deposit date: | 2013-03-22 | Release date: | 2013-05-15 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2.28 Å) | Cite: | Structural and Biochemical Characterization of Compounds Inhibiting Mycobacterium Tuberculosis Pank J.Biol.Chem., 288, 2013
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1E0K
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![BU of 1e0k by Molmil](/molmil-images/mine/1e0k) | gp4d helicase from phage T7 | Descriptor: | DNA HELICASE | Authors: | Singleton, M.R, Sawaya, M.R, Ellenberger, T, Wigley, D.B. | Deposit date: | 2000-03-30 | Release date: | 2000-06-09 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (3.3 Å) | Cite: | Crystal Structure of T7 Gene 4 Ring Helicase Indicates a Mechanism for Sequential Hydrolysis of Nucleotides Cell(Cambridge,Mass.), 101, 2000
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