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6OT1
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BU of 6ot1 by Molmil
Cryo-EM structure of vaccine-elicited antibody 0PV-b.01 in complex with HIV-1 Env BG505 DS-SOSIP and antibodies VRC03 and PGT122
Descriptor: 0PV-b.01 heavy, 0PV-b.01 light, 2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Gorman, J, Kwong, P.D.
Deposit date:2019-05-02
Release date:2019-08-07
Last modified:2020-07-29
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:Antibody Lineages with Vaccine-Induced Antigen-Binding Hotspots Develop Broad HIV Neutralization.
Cell, 178, 2019
6OSY
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BU of 6osy by Molmil
Cryo-EM structure of vaccine-elicited antibody 0PV-a.01 in complex with HIV-1 Env BG505 DS-SOSIP and antibodies VRC03 and PGT122
Descriptor: 0PV-a.01 Heavy, 0PV-a.01 Light, 2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Gorman, J, Kwong, P.D.
Deposit date:2019-05-02
Release date:2019-07-24
Last modified:2020-07-29
Method:ELECTRON MICROSCOPY (4.3 Å)
Cite:Antibody Lineages with Vaccine-Induced Antigen-Binding Hotspots Develop Broad HIV Neutralization.
Cell, 178, 2019
4MMR
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BU of 4mmr by Molmil
Crystal Structure of Prefusion-stabilized RSV F Variant Cav1 at pH 9.5
Descriptor: Fusion glycoprotein F1 fused with Fibritin trimerization domain, Fusion glycoprotein F2
Authors:Stewart-Jones, G.B.E, McLellan, J.S, Joyce, M.G, Sastry, M, Yang, Y, Graham, B.S, Kwong, P.D.
Deposit date:2013-09-09
Release date:2013-11-20
Last modified:2021-06-02
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Structure-based design of a fusion glycoprotein vaccine for respiratory syncytial virus.
Science, 342, 2013
4MMS
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BU of 4mms by Molmil
Crystal Structure of Prefusion-stabilized RSV F Variant Cav1 at pH 5.5
Descriptor: Fusion glycoprotein F1 fused with Fibritin trimerization domain, Fusion glycoprotein F2, SULFATE ION
Authors:Mclellan, J.S, Joyce, M.G, Stewart-Jones, G.B.E, Sastry, M, Yang, Y, Graham, B.S, Kwong, P.D.
Deposit date:2013-09-09
Release date:2013-11-20
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.397 Å)
Cite:Structure-based design of a fusion glycoprotein vaccine for respiratory syncytial virus.
Science, 342, 2013
4MMV
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BU of 4mmv by Molmil
Crystal Structure of Prefusion-stabilized RSV F Variant DS-Cav1-TriC at pH 9.5
Descriptor: Fusion glycoprotein F1 fused with Fibritin trimerization domain, Fusion glycoprotein F2
Authors:Stewart-Jones, G.B.E, McLellan, J.S, Joyce, M.G, Sastry, M, Yang, Y, Graham, B.S, Kwong, P.D.
Deposit date:2013-09-09
Release date:2013-11-20
Last modified:2021-06-02
Method:X-RAY DIFFRACTION (2.81 Å)
Cite:Structure-based design of a fusion glycoprotein vaccine for respiratory syncytial virus.
Science, 342, 2013
4MMU
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BU of 4mmu by Molmil
Crystal Structure of Prefusion-stabilized RSV F Variant DS-Cav1 at pH 5.5
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Fusion glycoprotein F1 fused with Fibritin trimerization domain, Fusion glycoprotein F2, ...
Authors:Joyce, M.G, Mclellan, J.S, Stewart-Jones, G.B.E, Sastry, M, Yang, Y, Graham, B.S, Kwong, P.D.
Deposit date:2013-09-09
Release date:2013-11-20
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (3 Å)
Cite:Structure-based design of a fusion glycoprotein vaccine for respiratory syncytial virus.
Science, 342, 2013
4MMT
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BU of 4mmt by Molmil
Crystal Structure of Prefusion-stabilized RSV F Variant DS-Cav1 at pH 9.5
Descriptor: Fusion glycoprotein F1 fused with Fibritin trimerization domain, Fusion glycoprotein F2
Authors:Joyce, M.G, Mclellan, J.S, Stewart-Jones, G.B.E, Sastry, M, Yang, Y, Graham, B.S, Kwong, P.D.
Deposit date:2013-09-09
Release date:2013-11-20
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (3.05 Å)
Cite:Structure-based design of a fusion glycoprotein vaccine for respiratory syncytial virus.
Science, 342, 2013
4MMQ
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BU of 4mmq by Molmil
Crystal Structure of Prefusion-stabilized RSV F Variant DS
Descriptor: Fusion glycoprotein F1 fused with Fibritin trimerization domain, Fusion glycoprotein F2, SULFATE ION
Authors:Mclellan, J.S, Joyce, M.G, Stewart-Jones, G.B.E, Sastry, M, Yang, Y, Graham, B.S, Kwong, P.D.
Deposit date:2013-09-09
Release date:2013-11-20
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (3.253 Å)
Cite:Structure-based design of a fusion glycoprotein vaccine for respiratory syncytial virus.
Science, 342, 2013
7SG4
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BU of 7sg4 by Molmil
Structure of SARS-CoV S protein in complex with Receptor Binding Domain antibody DH1047
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, DH1047 Heavy chain, DH1047 light chain, ...
Authors:Gobeil, S, Acharya, P.
Deposit date:2021-10-04
Release date:2021-11-10
Last modified:2022-02-09
Method:ELECTRON MICROSCOPY (3.43 Å)
Cite:A broadly cross-reactive antibody neutralizes and protects against sarbecovirus challenge in mice.
Sci Transl Med, 14, 2022
6UCE
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BU of 6uce by Molmil
N123-VRC34_pI3 HIV neutralizing antibody in complex with HIV fusion peptide residue 512-519
Descriptor: HIV fusion peptide, N123-VRC34_pI3 heavy chain, N123-VRC34_pI3 light chain
Authors:Xu, K, Kwong, P.D.
Deposit date:2019-09-16
Release date:2020-03-18
Last modified:2020-04-22
Method:X-RAY DIFFRACTION (1.382 Å)
Cite:VRC34-Antibody Lineage Development Reveals How a Required Rare Mutation Shapes the Maturation of a Broad HIV-Neutralizing Lineage.
Cell Host Microbe, 27, 2020
6UCF
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BU of 6ucf by Molmil
N123-VRC34_pI4 HIV neutralizing antibody in complex with HIV fusion peptide residue 512-519
Descriptor: HIV fusion peptide, N123-VRC34_pI4 heavy chain, N123-VRC34_pI4 light chain
Authors:Xu, K, Kwong, P.D.
Deposit date:2019-09-16
Release date:2020-03-18
Last modified:2020-04-22
Method:X-RAY DIFFRACTION (1.29 Å)
Cite:VRC34-Antibody Lineage Development Reveals How a Required Rare Mutation Shapes the Maturation of a Broad HIV-Neutralizing Lineage.
Cell Host Microbe, 27, 2020
6WIX
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BU of 6wix by Molmil
Crystal Structure of HIV-1 MI369 RnS-DS.SOSIP Prefusion Env Trimer in Complex with Human Antibodies 3H109L and 35O22 at 3.5 Angstrom
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Lai, Y.-T, Olia, A, Kwong, P.D.
Deposit date:2020-04-10
Release date:2020-11-25
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.67 Å)
Cite:Automated Design by Structure-Based Stabilization and Consensus Repair to Achieve Prefusion-Closed Envelope Trimers in a Wide Variety of HIV Strains.
Cell Rep, 33, 2020
7JZI
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BU of 7jzi by Molmil
Crystal structure of LAIR1 ectodomain (from MGD21) in complex with Plasmodium RIFIN (PF3D7_1040300) V2 domain
Descriptor: LAIR1 ectodomain from antibody MGD21, PLATINUM (II) ION, Rifin
Authors:Xu, K, Kwong, P.D.
Deposit date:2020-09-02
Release date:2021-05-26
Last modified:2021-09-22
Method:X-RAY DIFFRACTION (2.707 Å)
Cite:Structural basis of LAIR1 targeting by polymorphic Plasmodium RIFINs.
Nat Commun, 12, 2021
7JZK
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BU of 7jzk by Molmil
Crystal structure of LAIR1 ectodomain (from MGD21) in complex with Plasmodium RIFIN (PF3D7_0401300) V2 domain
Descriptor: LAIR1 ecotodomain from MGD21 antibody, Rifin, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose
Authors:Xu, K, Kwong, P.D.
Deposit date:2020-09-02
Release date:2021-05-26
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.457 Å)
Cite:Structural basis of LAIR1 targeting by polymorphic Plasmodium RIFINs.
Nat Commun, 12, 2021
7JZ4
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BU of 7jz4 by Molmil
Crystal structure of broadly Plasmodium RIFIN reactive LAIR1-inserted antibody MGD21
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, MGD21 heavy chain, MGD21 light chain, ...
Authors:Xu, K, Kwong, P.D.
Deposit date:2020-09-01
Release date:2021-05-26
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.747 Å)
Cite:Structural basis of LAIR1 targeting by polymorphic Plasmodium RIFINs.
Nat Commun, 12, 2021
7JZ1
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BU of 7jz1 by Molmil
Crystal structure of broadly Plasmodium RIFIN reactive LAIR1-inserted antibody MGC34
Descriptor: MGC34 heavy chain, MGC34 light chain
Authors:Xu, K, Kwong, P.D.
Deposit date:2020-09-01
Release date:2021-05-26
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (3.37 Å)
Cite:Structural basis of LAIR1 targeting by polymorphic Plasmodium RIFINs.
Nat Commun, 12, 2021
6WWC
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BU of 6wwc by Molmil
Vaccine-elicited mouse FP-targeting neutralizing antibody vFP16.02 with S48K mutation in light chain in complex with HIV fusion peptide (residue 512-519)
Descriptor: fusion peptide, vFP16.02 antibody heavy chain, vFP16.02 antibody light chain
Authors:Xu, K, Wang, Y, Kwong, P.D.
Deposit date:2020-05-09
Release date:2021-02-24
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.563 Å)
Cite:Mutational fitness landscapes reveal genetic and structural improvement pathways for a vaccine-elicited HIV-1 broadly neutralizing antibody.
Proc.Natl.Acad.Sci.USA, 118, 2021
8F7T
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BU of 8f7t by Molmil
Glycan-Base ConC Env Trimer
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-6)-2-acetamido-2-deoxy-beta-D-glucopyranose, HIV-1 Env gp120, ...
Authors:Olia, A.S, Kwong, P.D.
Deposit date:2022-11-20
Release date:2023-09-27
Method:ELECTRON MICROSCOPY (4.1 Å)
Cite:Soluble prefusion-closed HIV-envelope trimers with glycan-covered bases.
Iscience, 26, 2023
8FR6
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BU of 8fr6 by Molmil
Antibody vFP53.02 in complex with HIV-1 envelope trimer BG505 DS-SOSIP
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Envelope glycoprotein gp120, ...
Authors:Wang, S, Kwong, P.D.
Deposit date:2023-01-06
Release date:2023-04-19
Last modified:2023-06-07
Method:ELECTRON MICROSCOPY (2.5 Å)
Cite:Diverse Murine Vaccinations Reveal Distinct Antibody Classes to Target Fusion Peptide and Variation in Peptide Length to Improve HIV Neutralization.
J.Virol., 97, 2023
8G9W
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BU of 8g9w by Molmil
Cryo-EM structure of vFP49.02 Fab in complex with HIV-1 Env BG505 DS-SOSIP.664 (conformation 1)
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Envelope glycoprotein gp120, ...
Authors:Changela, A, Gorman, J, Kwong, P.D.
Deposit date:2023-02-22
Release date:2023-04-19
Last modified:2023-06-14
Method:ELECTRON MICROSCOPY (4.66 Å)
Cite:Diverse Murine Vaccinations Reveal Distinct Antibody Classes to Target Fusion Peptide and Variation in Peptide Length to Improve HIV Neutralization.
J.Virol., 97, 2023
8G9Y
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BU of 8g9y by Molmil
Cryo-EM structure of vFP49.02 Fab in complex with HIV-1 Env BG505 DS-SOSIP.664 (conformation 3)
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Envelope glycoprotein gp120, ...
Authors:Changela, A, Gorman, J, Kwong, P.D.
Deposit date:2023-02-22
Release date:2023-04-19
Last modified:2023-06-14
Method:ELECTRON MICROSCOPY (4.28 Å)
Cite:Diverse Murine Vaccinations Reveal Distinct Antibody Classes to Target Fusion Peptide and Variation in Peptide Length to Improve HIV Neutralization.
J.Virol., 97, 2023
8G85
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BU of 8g85 by Molmil
vFP52.02 Fab in complex with BG505 DS-SOSIP Env trimer
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Envelope glycoprotein gp120, ...
Authors:Gorman, J, Kwong, P.D.
Deposit date:2023-02-17
Release date:2023-04-19
Last modified:2023-06-14
Method:ELECTRON MICROSCOPY (3.99 Å)
Cite:Diverse Murine Vaccinations Reveal Distinct Antibody Classes to Target Fusion Peptide and Variation in Peptide Length to Improve HIV Neutralization.
J.Virol., 97, 2023
8GAS
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BU of 8gas by Molmil
vFP48.02 Fab in complex with BG505 DS-SOSIP Env trimer
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Envelope glycoprotein gp120, ...
Authors:Gorman, J, Kwong, P.D.
Deposit date:2023-02-23
Release date:2023-04-19
Last modified:2023-06-14
Method:ELECTRON MICROSCOPY (4.04 Å)
Cite:Diverse Murine Vaccinations Reveal Distinct Antibody Classes to Target Fusion Peptide and Variation in Peptide Length to Improve HIV Neutralization.
J.Virol., 97, 2023
8G9X
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BU of 8g9x by Molmil
Cryo-EM structure of vFP49.02 Fab in complex with HIV-1 Env BG505 DS-SOSIP.664 (conformation 2)
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Envelope glycoprotein gp120, ...
Authors:Changela, A, Gorman, J, Kwong, P.D.
Deposit date:2023-02-22
Release date:2023-04-19
Last modified:2023-06-14
Method:ELECTRON MICROSCOPY (4.46 Å)
Cite:Diverse Murine Vaccinations Reveal Distinct Antibody Classes to Target Fusion Peptide and Variation in Peptide Length to Improve HIV Neutralization.
J.Virol., 97, 2023
7UTF
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BU of 7utf by Molmil
Structure-Function characterization of an aldo-keto reductase involved in detoxification of the mycotoxin, deoxynivalenol
Descriptor: CITRATE ANION, Putative oxidoreductase, aryl-alcohol dehydrogenase like protein, ...
Authors:Abraham, N, Schroeter, K.L, Kimber, M.S, Seah, S.Y.K.
Deposit date:2022-04-26
Release date:2022-09-07
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structure-function characterization of an aldo-keto reductase involved in detoxification of the mycotoxin, deoxynivalenol.
Sci Rep, 12, 2022

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数据于2024-06-12公开中

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