5WFW
| Crystal structure of the influenza virus PA endonuclease (E119D mutant) in complex with inhibitor 10j (SRI-30026) | Descriptor: | 2-[(2S)-1-{[(2-chlorophenyl)sulfanyl]acetyl}pyrrolidin-2-yl]-N-(5,6-dimethoxy-2,3-dihydro-1H-inden-2-yl)-5-hydroxy-6-ox o-1,6-dihydropyrimidine-4-carboxamide, MANGANESE (II) ION, Polymerase acidic protein, ... | Authors: | Kumar, G, White, S.W. | Deposit date: | 2017-07-12 | Release date: | 2018-01-03 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (2.292 Å) | Cite: | Protein-Structure Assisted Optimization of 4,5-Dihydroxypyrimidine-6-Carboxamide Inhibitors of Influenza Virus Endonuclease. Sci Rep, 7, 2017
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5W3I
| Crystal structure of the influenza virus PA endonuclease in complex with inhibitor 6e (SRI-29685) | Descriptor: | 5-hydroxy-N-(2-methoxyethyl)-6-oxo-2-[(2S)-1-(phenoxyacetyl)pyrrolidin-2-yl]-1,6-dihydropyrimidine-4-carboxamide, GLYCEROL, MANGANESE (II) ION, ... | Authors: | Kumar, G, White, S.W. | Deposit date: | 2017-06-07 | Release date: | 2017-12-27 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (1.95 Å) | Cite: | Protein-Structure Assisted Optimization of 4,5-Dihydroxypyrimidine-6-Carboxamide Inhibitors of Influenza Virus Endonuclease. Sci Rep, 7, 2017
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5W44
| Crystal structure of the influenza virus PA endonuclease in complex with inhibitor 7a (SRI-29770) | Descriptor: | 2-[(2S)-1-(2,6-dichlorobenzene-1-carbonyl)pyrrolidin-2-yl]-5-hydroxy-6-oxo-N-(2-phenylethyl)-1,6-dihydropyrimidine-4-carboxamide, MAGNESIUM ION, MANGANESE (II) ION, ... | Authors: | Kumar, G, White, S.W. | Deposit date: | 2017-06-09 | Release date: | 2018-01-10 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Protein-Structure Assisted Optimization of 4,5-Dihydroxypyrimidine-6-Carboxamide Inhibitors of Influenza Virus Endonuclease. Sci Rep, 7, 2017
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5WDW
| Crystal structure of the influenza virus PA endonuclease in complex with inhibitor 10k (SRI-30027) | Descriptor: | 2-[(2S)-1-{[(2-chlorophenyl)sulfanyl]acetyl}pyrrolidin-2-yl]-N-{[(2S)-2,3-dihydro-1-benzofuran-2-yl]methyl}-5-hydroxy-6-oxo-1,6-dihydropyrimidine-4-carboxamide, MANGANESE (II) ION, Polymerase acidic protein | Authors: | Kumar, G, White, S.W. | Deposit date: | 2017-07-06 | Release date: | 2018-01-03 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Protein-Structure Assisted Optimization of 4,5-Dihydroxypyrimidine-6-Carboxamide Inhibitors of Influenza Virus Endonuclease. Sci Rep, 7, 2017
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5WA6
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5WG9
| Crystal structure of the influenza virus PA endonuclease (E119D mutant) in complex with inhibitor 9b (SRI-30101) | Descriptor: | 2-{(2S)-1-[3-(2-chlorophenyl)propanoyl]pyrrolidin-2-yl}-5-hydroxy-6-oxo-N-(2-phenoxyethyl)-1,6-dihydropyrimidine-4-carboxamide, MANGANESE (II) ION, Polymerase acidic protein, ... | Authors: | Kumar, G, White, S.W. | Deposit date: | 2017-07-13 | Release date: | 2018-01-03 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Protein-Structure Assisted Optimization of 4,5-Dihydroxypyrimidine-6-Carboxamide Inhibitors of Influenza Virus Endonuclease. Sci Rep, 7, 2017
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5WAP
| Crystal structure of the influenza virus PA endonuclease in complex with inhibitor 10i (SRI-30025) | Descriptor: | 2-[(2S)-1-{[(2-chlorophenyl)sulfanyl]acetyl}pyrrolidin-2-yl]-N-(2,3-dihydro-1H-inden-2-yl)-5-hydroxy-6-oxo-1,6-dihydropyrimidine-4-carboxamide, MANGANESE (II) ION, Polymerase acidic protein, ... | Authors: | Kumar, G, White, S.W. | Deposit date: | 2017-06-26 | Release date: | 2018-01-03 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (2.201 Å) | Cite: | Protein-Structure Assisted Optimization of 4,5-Dihydroxypyrimidine-6-Carboxamide Inhibitors of Influenza Virus Endonuclease. Sci Rep, 7, 2017
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5WDN
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5WCT
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1TX0
| Dihydropteroate Synthetase, With Bound Product Analogue Pteroic Acid, From Bacillus anthracis | Descriptor: | DHPS, Dihydropteroate synthase, PTEROIC ACID, ... | Authors: | Babaoglu, K, Qi, J, Lee, R.E, White, S.W. | Deposit date: | 2004-07-01 | Release date: | 2004-09-14 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (2.15 Å) | Cite: | Crystal Structure of 7,8-Dihydropteroate Synthase from Bacillus anthracis; Mechanism and Novel Inhibitor Design. STRUCTURE, 12, 2004
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1TWZ
| Dihydropteroate Synthetase, With Bound Substrate Analogue PtP, From Bacillus anthracis | Descriptor: | DHPS, Dihydropteroate synthase, PTERIN-6-YL-METHYL-MONOPHOSPHATE, ... | Authors: | Babaoglu, K, Qi, J, Lee, R.L, White, S.W. | Deposit date: | 2004-07-01 | Release date: | 2004-09-14 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (2.75 Å) | Cite: | Crystal Structure of 7,8-Dihydropteroate Synthase from Bacillus anthracis; Mechanism and Novel Inhibitor Design. STRUCTURE, 12, 2004
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1TWS
| Dihydropteroate Synthetase From Bacillus anthracis | Descriptor: | DHPS, Dihydropteroate synthase, SULFATE ION | Authors: | Babaoglu, K, Qi, J, Lee, R.E, White, S.W. | Deposit date: | 2004-07-01 | Release date: | 2004-09-14 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Crystal Structure of 7,8-Dihydropteroate Synthase from Bacillus anthracis; Mechanism and Novel Inhibitor Design. STRUCTURE, 12, 2004
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1TX2
| Dihydropteroate Synthetase, With Bound Inhibitor MANIC, From Bacillus anthracis | Descriptor: | 6-METHYLAMINO-5-NITROISOCYTOSINE, DHPS, Dihydropteroate synthase, ... | Authors: | Babaoglu, K, Qi, J, Lee, R.E, White, S.W. | Deposit date: | 2004-07-01 | Release date: | 2004-09-14 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (1.83 Å) | Cite: | Crystal Structure of 7,8-Dihydropteroate Synthase from Bacillus anthracis; Mechanism and Novel Inhibitor Design. STRUCTURE, 12, 2004
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1RIP
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1RIF
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1SEI
| STRUCTURE OF 30S RIBOSOMAL PROTEIN S8 | Descriptor: | RIBOSOMAL PROTEIN S8 | Authors: | Davies, C, Ramakrishnan, V, White, S.W. | Deposit date: | 1996-08-14 | Release date: | 1997-03-12 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Structural evidence for specific S8-RNA and S8-protein interactions within the 30S ribosomal subunit: ribosomal protein S8 from Bacillus stearothermophilus at 1.9 A resolution. Structure, 4, 1996
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1TWW
| Dihydropteroate Synthetase, With Bound Substrate Analogue PtPP, From Bacillus anthracis | Descriptor: | 6-HYDROXYMETHYLPTERIN-DIPHOSPHATE, DHPS, Dihydropteroate synthase, ... | Authors: | Babaoglu, K, Qi, J, Lee, R.E, White, S.W. | Deposit date: | 2004-07-01 | Release date: | 2004-09-14 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Crystal Structure of 7,8-Dihydropteroate Synthase from Bacillus anthracis; Mechanism and Novel Inhibitor Design. STRUCTURE, 12, 2004
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1DIV
| RIBOSOMAL PROTEIN L9 | Descriptor: | RIBOSOMAL PROTEIN L9 | Authors: | Hoffman, D.W, Cameron, C, Davies, C, Gerchman, S.E, Kycia, J.H, Porter, S, Ramakrishnan, V, White, S.W. | Deposit date: | 1996-07-02 | Release date: | 1997-01-11 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Crystal structure of prokaryotic ribosomal protein L9: a bi-lobed RNA-binding protein. EMBO J., 13, 1994
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4Q9N
| Crystal structure of Chlamydia trachomatis enoyl-ACP reductase (FabI) in complex with NADH and AFN-1252 | Descriptor: | 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, Enoyl-[acyl-carrier-protein] reductase [NADH], N-methyl-N-[(3-methyl-1-benzofuran-2-yl)methyl]-3-(7-oxo-5,6,7,8-tetrahydro-1,8-naphthyridin-3-yl)propanamide | Authors: | Yao, J, Abdelrahman, Y, Robertson, R.M, Cox, J.V, Belland, R.J, White, S.W, Rock, C.O. | Deposit date: | 2014-05-01 | Release date: | 2014-06-25 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (1.795 Å) | Cite: | Type II Fatty Acid Synthesis Is Essential for the Replication of Chlamydia trachomatis. J.Biol.Chem., 289, 2014
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4NIR
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4NHV
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4NIL
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3S13
| Crystal structure of H5N1 influenza virus hemagglutinin, strain YU562 crystal form 2 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin HA1 chain, Hemagglutinin HA2 chain, ... | Authors: | DuBois, R.M, Zaraket, H, Reddivari, M, Heath, R.J, White, S.W, Russell, C.J. | Deposit date: | 2011-05-14 | Release date: | 2011-12-14 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (2.96 Å) | Cite: | Acid stability of the hemagglutinin protein regulates H5N1 influenza virus pathogenicity. Plos Pathog., 7, 2011
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3S11
| Crystal structure of H5N1 influenza virus hemagglutinin, strain 437-10 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, GLYCEROL, ... | Authors: | DuBois, R.M, Zaraket, H, Reddivari, M, Heath, R.J, White, S.W, Russell, C.J. | Deposit date: | 2011-05-14 | Release date: | 2011-12-14 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Acid stability of the hemagglutinin protein regulates H5N1 influenza virus pathogenicity. Plos Pathog., 7, 2011
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3S12
| Crystal structure of H5N1 influenza virus hemagglutinin, strain YU562 crystal form 1 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin HA1 chain, ... | Authors: | DuBois, R.M, Zaraket, H, Reddivari, M, Heath, R.J, White, S.W, Russell, C.J. | Deposit date: | 2011-05-14 | Release date: | 2011-12-14 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (3.1 Å) | Cite: | Acid stability of the hemagglutinin protein regulates H5N1 influenza virus pathogenicity. Plos Pathog., 7, 2011
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