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2QZ9
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BU of 2qz9 by Molmil
crystal structure of aspartate semialdehyde dehydrogenase II from vibrio cholerae
Descriptor: Aspartate-semialdehyde dehydrogenase
Authors:Viola, R.E, Liu, X, Ohren, J.F, Faehnle, C.R.
Deposit date:2007-08-16
Release date:2008-04-08
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:The structure of a redundant enzyme: a second isoform of aspartate beta-semialdehyde dehydrogenase in Vibrio cholerae.
Acta Crystallogr.,Sect.D, 64, 2008
2R00
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BU of 2r00 by Molmil
crystal structure of aspartate semialdehyde dehydrogenase II complexed with ASA from vibrio cholerae
Descriptor: 2,2'-oxydiacetic acid, Aspartate-semialdehyde dehydrogenase
Authors:Viola, R.E, Liu, X, Ohren, J.F, Faehnle, C.R.
Deposit date:2007-08-17
Release date:2008-04-08
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.03 Å)
Cite:The structure of a redundant enzyme: a second isoform of aspartate beta-semialdehyde dehydrogenase in Vibrio cholerae.
Acta Crystallogr.,Sect.D, 64, 2008
1TB4
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BU of 1tb4 by Molmil
Crystal Structure of Aspartate-Semialdehyde Dehydrogenase From Haemophilus influenzae with a Bound Periodate
Descriptor: Aspartate-semialdehyde dehydrogenase, PERIODATE
Authors:Viola, R.E.
Deposit date:2004-05-19
Release date:2004-12-07
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:Structural basis for discrimination between oxyanion substrates or inhibitors in aspartate-beta-semialdehyde dehydrogenase.
Acta Crystallogr.,Sect.D, 60, 2004
1TA4
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BU of 1ta4 by Molmil
Crystal Structure Of Aspartate-Semialdehyde Dehydrogenase From Haemophilus Influenzae with a Bound Arsenate
Descriptor: ARSENATE, Aspartate-semialdehyde dehydrogenase
Authors:Viola, R.E.
Deposit date:2004-05-19
Release date:2004-12-07
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.28 Å)
Cite:Structural basis for discrimination between oxyanion substrates or inhibitors in aspartate-beta-semialdehyde dehydrogenase.
Acta Crystallogr.,Sect.D, 60, 2004
3C20
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BU of 3c20 by Molmil
Crystal Structure of Threonine-sensitive Aspartokinase from Methanococcus jannaschii with L-aspartate
Descriptor: ASPARTIC ACID, FORMIC ACID, Probable aspartokinase
Authors:Liu, X, Pavlovsky, A.G, Viola, R.E.
Deposit date:2008-01-24
Release date:2008-04-29
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:The Structural Basis for Allosteric Inhibition of a Threonine-sensitive Aspartokinase.
J.Biol.Chem., 283, 2008
4MXU
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BU of 4mxu by Molmil
Human brain aspartoacylase mutant K213E complex with intermediate analog (N-phosphonomethyl-L-aspartate)
Descriptor: Aspartoacylase, N-[HYDROXY(METHYL)PHOSPHORYL]-L-ASPARTIC ACID, ZINC ION
Authors:Wijayasinghe, Y.S, Pavlovsky, A.G, Viola, R.E.
Deposit date:2013-09-26
Release date:2014-07-30
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Aspartoacylase catalytic deficiency as the cause of canavan disease: a structural perspective.
Biochemistry, 53, 2014
4MRI
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BU of 4mri by Molmil
Human brain aspartoacylase mutant F295S complex with intermediate analog (N-phosphonomethyl-L-aspartate)
Descriptor: Aspartoacylase, N-[HYDROXY(METHYL)PHOSPHORYL]-L-ASPARTIC ACID, ZINC ION
Authors:Wijayasinghe, Y.S, Pavlovsky, A.G, Viola, R.E.
Deposit date:2013-09-17
Release date:2014-07-30
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Aspartoacylase catalytic deficiency as the cause of canavan disease: a structural perspective.
Biochemistry, 53, 2014
5JW6
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BU of 5jw6 by Molmil
Cystal structure of aspartate semialdehyde dehydrogenase from Aspergillus fumigatus
Descriptor: Aspartate-semialdehyde dehydrogenase, SULFATE ION
Authors:Dahal, G.P, Viola, R.E.
Deposit date:2016-05-11
Release date:2017-01-11
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.39 Å)
Cite:Structure of a fungal form of aspartate-semialdehyde dehydrogenase from Aspergillus fumigatus.
Acta Crystallogr F Struct Biol Commun, 73, 2017
3HSK
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BU of 3hsk by Molmil
Crystal Structure of Aspartate Semialdehyde Dehydrogenase with NADP from Candida albicans
Descriptor: Aspartate-semialdehyde dehydrogenase, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
Authors:Arachea, B.T, Pavlovsky, A, Liu, X, Viola, R.E.
Deposit date:2009-06-10
Release date:2010-02-02
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Expansion of the aspartate beta-semialdehyde dehydrogenase family: the first structure of a fungal ortholog.
Acta Crystallogr.,Sect.D, 66, 2010
4LE5
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BU of 4le5 by Molmil
Structure of an Unusual S-adenosylmethionine synthetase from Campylobacter jejuni
Descriptor: S-adenosylmethionine synthetase
Authors:Zano, S.P, Pavlovsky, A.G, Viola, R.E.
Deposit date:2013-06-25
Release date:2014-02-12
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Structure of an unusual S-adenosylmethionine synthetase from Campylobacter jejuni.
Acta Crystallogr.,Sect.D, 70, 2014
2YXP
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BU of 2yxp by Molmil
The Effect of Deuteration on Protein Structure A High Resolution Comparison of Hydrogenous and Perdeuterated Haloalkane Dehalogenase
Descriptor: Haloalkane dehalogenase
Authors:Liu, X, Hanson, L, Langan, P, Viola, R.E.
Deposit date:2007-04-27
Release date:2007-09-04
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (1.53 Å)
Cite:The effect of deuteration on protein structure: a high-resolution comparison of hydrogenous and perdeuterated haloalkane dehalogenase.
Acta Crystallogr.,Sect.D, 63, 2007
4R5M
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BU of 4r5m by Molmil
Crystal structure of Vc-Aspartate beta-semialdehyde-dehydrogenase with NADP and 4-Nitro-2-Phosphono-Benzoic acid
Descriptor: 4-nitro-2-phosphonobenzoic acid, Aspartate-semialdehyde dehydrogenase 1, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ...
Authors:Pavlovsky, A.G, Thangavelu, B, Bhansali, P, Viola, R.E.
Deposit date:2014-08-21
Release date:2014-12-10
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.89 Å)
Cite:A cautionary tale of structure-guided inhibitor development against an essential enzyme in the aspartate-biosynthetic pathway.
Acta Crystallogr.,Sect.D, 70, 2014
4R54
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BU of 4r54 by Molmil
Complex crystal structure of sp-Aspartate-Semialdehyde-Dehydrogenase with 3-carboxy-ethyl-phthalic acid
Descriptor: 3-(2-carboxyethyl)benzene-1,2-dicarboxylic acid, ACETATE ION, Aspartate-semialdehyde dehydrogenase, ...
Authors:Pavlovsky, A.G, Viola, R.E.
Deposit date:2014-08-20
Release date:2014-12-10
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.81 Å)
Cite:A cautionary tale of structure-guided inhibitor development against an essential enzyme in the aspartate-biosynthetic pathway.
Acta Crystallogr.,Sect.D, 70, 2014
4TNU
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BU of 4tnu by Molmil
Human brain aspartoacylase mutant Y231C complex with intermediate analog (N-phosphonomethyl-L-aspartate)
Descriptor: Aspartoacylase, N-[HYDROXY(METHYL)PHOSPHORYL]-L-ASPARTIC ACID, ZINC ION
Authors:Wijayasinghe, Y.S, Pavlovsky, A.G, Viola, R.E.
Deposit date:2014-06-05
Release date:2014-07-30
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Aspartoacylase catalytic deficiency as the cause of canavan disease: a structural perspective.
Biochemistry, 53, 2014
3C1N
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BU of 3c1n by Molmil
Crystal Structure of Allosteric Inhibition Threonine-sensitive Aspartokinase from Methanococcus jannaschii with L-threonine
Descriptor: Probable aspartokinase, THREONINE
Authors:Liu, X, Pavlovshy, A.G, Viola, R.E.
Deposit date:2008-01-23
Release date:2008-03-25
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.72 Å)
Cite:The Structural Basis for Allosteric Inhibition of a Threonine-sensitive Aspartokinase.
J.Biol.Chem., 283, 2008
3FMX
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BU of 3fmx by Molmil
Crystal structure of Tartrate dehydrogenase from Pseudomonas putida complexed with NADH
Descriptor: 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, AMMONIUM ION, Tartrate dehydrogenase/decarboxylase
Authors:Malik, R, Viola, R.E.
Deposit date:2008-12-22
Release date:2010-01-12
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.95 Å)
Cite:Structural Characterization of Tartrate Dehydrogenase: a versatile enzyme catalyzing multiple reactions
To be Published
3FLK
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BU of 3flk by Molmil
Crystal Structure of Tartrate Dehydrogenase from Pseudomonas putida in complex with NADH, oxalate and metal ion
Descriptor: 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, 2,3-DIHYDROXY-1,4-DITHIOBUTANE, AMMONIUM ION, ...
Authors:Malik, R, Viola, R.E.
Deposit date:2008-12-18
Release date:2009-12-22
Last modified:2024-10-30
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural characterization of tartrate dehydrogenase: a versatile enzyme catalyzing multiple reactions.
Acta Crystallogr.,Sect.D, 66, 2010
6C07
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BU of 6c07 by Molmil
Crystal Structure of S-Adenosylmethionine synthetase (MetK/Mat) from Cryptosporidium parvum
Descriptor: CHLORIDE ION, MAGNESIUM ION, POTASSIUM ION, ...
Authors:Ohren, J.F, Viola, R.E.
Deposit date:2017-12-28
Release date:2019-01-16
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Structure of a critical metabolic enzyme: S-adenosylmethionine synthetase from Cryptosporidium parvum.
Acta Crystallogr F Struct Biol Commun, 75, 2019
6C8W
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BU of 6c8w by Molmil
Crystal structure of Aspartate Semialdehyde Dehydrogenase with NADP from Blastomyces dermatitidis
Descriptor: Aspartate-semialdehyde dehydrogenase, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
Authors:Dahal, G.P, Viola, R.E.
Deposit date:2018-01-25
Release date:2019-01-30
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structural insights into inhibitor binding to a fungal ortholog of aspartate semialdehyde dehydrogenase.
Biochem.Biophys.Res.Commun., 503, 2018
6C85
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Crystal structure of aspartate semialdehyde dehydrogenase from Blastomyces dermatitidis with p-benzoquinone
Descriptor: 1,4-benzoquinone, Aspartate-semialdehyde dehydrogenase
Authors:Dahal, G.P, Viola, R.E.
Deposit date:2018-01-24
Release date:2019-01-30
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structural insights into inhibitor binding to a fungal ortholog of aspartate semialdehyde dehydrogenase.
Biochem.Biophys.Res.Commun., 503, 2018
5CEF
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BU of 5cef by Molmil
Cystal structure of aspartate semialdehyde dehydrogenase from Cryptococcus neoformans
Descriptor: 1,2-ETHANEDIOL, Aspartate-semialdehyde dehydrogenase
Authors:Dahal, G.P, Viola, R.E.
Deposit date:2015-07-06
Release date:2015-11-18
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structure of a fungal form of aspartate semialdehyde dehydrogenase from Cryptococcus neoformans.
Acta Crystallogr.,Sect.F, 71, 2015
3PWK
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BU of 3pwk by Molmil
Crystal Structure of Aspartate beta-Semialdehide Dehydrogenase from Streptococcus pneumoniae with 2',5'-Adenosine diphosphate and D-2-aminoadipate
Descriptor: 1,2-ETHANEDIOL, 5'-O-MONOPHOSPHORYLADENYLYL(2'->5')ADENYLYL(2'->5')ADENOSINE, Aspartate-semialdehyde dehydrogenase, ...
Authors:Pavlovsky, A.G, Viola, R.E.
Deposit date:2010-12-08
Release date:2012-01-04
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Structural Characterization of Inhibitors with Selectivity against Members of a Homologous Enzyme Family.
Chem.Biol.Drug Des., 79, 2012
3PZR
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BU of 3pzr by Molmil
Crystals structure of aspartate beta-Semialdehyde dehydrogenase from Vibrio Cholerae with NADP and product of S-carbamoyl-L-cysteine
Descriptor: Aspartate-semialdehyde dehydrogenase, CYSTEINE, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ...
Authors:Pavlovsky, A.G, Potente, N, Viola, R.E.
Deposit date:2010-12-14
Release date:2012-01-04
Last modified:2024-10-16
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Structural Characterization of Inhibitors with Selectivity against Members of a Homologous Enzyme Family.
Chem.Biol.Drug Des., 79, 2012
3Q11
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BU of 3q11 by Molmil
Crystals Structure of Aspartate beta-Semialdehyde Dehydrogenase from Streptococcus pneumoniae with NADP and aspartyl beta-difluorophosphonate
Descriptor: 1,2-ETHANEDIOL, 5,5-difluoro-4-oxo-5-phosphono-D-norvaline, Aspartate-semialdehyde dehydrogenase, ...
Authors:Pavlovsky, A.G, Viola, R.E, Faehnle, C.R.
Deposit date:2010-12-16
Release date:2012-01-04
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structural Characterization of Inhibitors with Selectivity against Members of a Homologous Enzyme Family.
Chem.Biol.Drug Des., 79, 2012
3PYL
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BU of 3pyl by Molmil
Crystal structure of aspartate beta-semialdehide dehydrogenase from Streptococcus pneumoniae with D-2,3-diaminopropionate
Descriptor: 3-amino-D-alanine, Aspartate-semialdehyde dehydrogenase
Authors:Pavlovsky, A.G, Liu, X, Faehnle, C.R, Potente, N, Viola, R.E.
Deposit date:2010-12-13
Release date:2012-01-04
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structural Characterization of Inhibitors with Selectivity against Members of a Homologous Enzyme Family.
Chem.Biol.Drug Des., 79, 2012

 

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