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5G5T
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BU of 5g5t by Molmil
Structure of the Argonaute protein from Methanocaldcoccus janaschii in complex with guide DNA
Descriptor: ARGONAUTE, GUIDE DNA, MAGNESIUM ION, ...
Authors:Schneider, S, Oellig, C.A, Keegan, R, Grohmann, D, Zander, A, Willkomm, S.
Deposit date:2016-06-03
Release date:2017-02-08
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.85 Å)
Cite:Structural and mechanistic insights into an archaeal DNA-guided Argonaute protein.
Nat Microbiol, 2, 2017
5G5S
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BU of 5g5s by Molmil
Structure of the Argonaute protein from Methanocaldcoccus janaschii
Descriptor: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, ARGONAUTE, MAGNESIUM ION
Authors:Schneider, S, Oellig, C.A, Keegan, R, Grohmann, D, Zander, A, Willkomm, S.
Deposit date:2016-06-03
Release date:2017-02-08
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (2.29 Å)
Cite:Structural and mechanistic insights into an archaeal DNA-guided Argonaute protein.
Nat Microbiol, 2, 2017
3KR4
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BU of 3kr4 by Molmil
Structure of a protease 3
Descriptor: 2-(3-AMINO-2-HYDROXY-4-PHENYL-BUTYRYLAMINO)-4-METHYL-PENTANOIC ACID, CARBONATE ION, M17 leucyl aminopeptidase, ...
Authors:McGowan, S, Whisstock, J.C.
Deposit date:2009-11-17
Release date:2010-02-02
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structure of the Plasmodium falciparum M17 aminopeptidase and significance for the design of drugs targeting the neutral exopeptidases
Proc.Natl.Acad.Sci.USA, 107, 2010
3KR5
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BU of 3kr5 by Molmil
Structure of a protease 4
Descriptor: (2S)-3-[(R)-[(1S)-1-amino-3-phenylpropyl](hydroxy)phosphoryl]-2-benzylpropanoic acid, CARBONATE ION, M17 leucyl aminopeptidase, ...
Authors:McGowan, S, Whisstock, J.C.
Deposit date:2009-11-17
Release date:2010-02-02
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.56 Å)
Cite:Structure of the Plasmodium falciparum M17 aminopeptidase and significance for the design of drugs targeting the neutral exopeptidases
Proc.Natl.Acad.Sci.USA, 107, 2010
4WVM
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BU of 4wvm by Molmil
Stonustoxin structure
Descriptor: Stonustoxin subunit alpha, Stonustoxin subunit beta
Authors:Ellisdon, A.M, Panjikar, S, Whisstock, J.C, McGowan, S.
Deposit date:2014-11-06
Release date:2015-12-02
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Stonefish toxin defines an ancient branch of the perforin-like superfamily.
Proc.Natl.Acad.Sci.USA, 112, 2015
4EME
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BU of 4eme by Molmil
X-ray crystal structure and specificity of the Plasmodium falciparum malaria aminopeptidase
Descriptor: M18 aspartyl aminopeptidase, ZINC ION
Authors:McGowan, S.
Deposit date:2012-04-11
Release date:2012-06-27
Last modified:2013-01-02
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:X-ray crystal structure and specificity of the Plasmodium falciparum malaria aminopeptidase PfM18AAP.
J.Mol.Biol., 422, 2012
3KQZ
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BU of 3kqz by Molmil
Structure of a protease 2
Descriptor: CARBONATE ION, M17 leucyl aminopeptidase, NONAETHYLENE GLYCOL, ...
Authors:McGowan, S, Whisstock, J.C.
Deposit date:2009-11-17
Release date:2010-02-02
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.39 Å)
Cite:Structure of the Plasmodium falciparum M17 aminopeptidase and significance for the design of drugs targeting the neutral exopeptidases
Proc.Natl.Acad.Sci.USA, 107, 2010
3KQX
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BU of 3kqx by Molmil
Structure of a protease 1
Descriptor: CARBONATE ION, M17 leucyl aminopeptidase, NONAETHYLENE GLYCOL, ...
Authors:McGowan, S, Whisstock, J.C.
Deposit date:2009-11-17
Release date:2010-02-02
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.01 Å)
Cite:Structure of the Plasmodium falciparum M17 aminopeptidase and significance for the design of drugs targeting the neutral exopeptidases
Proc.Natl.Acad.Sci.USA, 107, 2010
3Q44
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BU of 3q44 by Molmil
X-ray crystal structure of PfA-M1 bound to Bestatin derivative 16
Descriptor: GLYCEROL, M1 family aminopeptidase, MAGNESIUM ION, ...
Authors:McGowan, S, Greenbaum, D.C.
Deposit date:2010-12-22
Release date:2011-03-16
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Synthesis of new (-)-bestatin-based inhibitor libraries reveals a novel binding mode in the s1 pocket of the essential malaria m1 metalloaminopeptidase.
J.Med.Chem., 54, 2011
3Q43
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BU of 3q43 by Molmil
X-ray crystal structure of PfA-M1 bound to bestatin derivative 15
Descriptor: GLYCEROL, M1 family aminopeptidase, MAGNESIUM ION, ...
Authors:McGowan, S, Greenbaum, D.C.
Deposit date:2010-12-22
Release date:2011-03-16
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Synthesis of new (-)-bestatin-based inhibitor libraries reveals a novel binding mode in the s1 pocket of the essential malaria m1 metalloaminopeptidase.
J.Med.Chem., 54, 2011
4K5P
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BU of 4k5p by Molmil
Phosphonic Arginine Mimetics as Inhibitors of the M1 Aminopeptidases from Plasmodium falciparum
Descriptor: GLYCEROL, M1 family aminopeptidase, MAGNESIUM ION, ...
Authors:McGowan, S.
Deposit date:2013-04-15
Release date:2013-06-12
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Synthesis and Structure-Activity Relationships of Phosphonic Arginine Mimetics as Inhibitors of the M1 and M17 Aminopeptidases from Plasmodium falciparum.
J.Med.Chem., 56, 2013
4K5N
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BU of 4k5n by Molmil
Phosphonic Arginine Mimetics as Inhibitors of the M1 Aminopeptidases from Plasmodium falciparum
Descriptor: GLYCEROL, M1 family aminopeptidase, MAGNESIUM ION, ...
Authors:McGowan, S.
Deposit date:2013-04-15
Release date:2013-06-12
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.91 Å)
Cite:Synthesis and Structure-Activity Relationships of Phosphonic Arginine Mimetics as Inhibitors of the M1 and M17 Aminopeptidases from Plasmodium falciparum.
J.Med.Chem., 56, 2013
4K5M
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BU of 4k5m by Molmil
Phosphonic Arginine Mimetics as Inhibitors of the M1 Aminopeptidases from Plasmodium falciparum
Descriptor: GLYCEROL, M1 family aminopeptidase, MAGNESIUM ION, ...
Authors:McGowan, S.
Deposit date:2013-04-14
Release date:2013-06-12
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Synthesis and Structure-Activity Relationships of Phosphonic Arginine Mimetics as Inhibitors of the M1 and M17 Aminopeptidases from Plasmodium falciparum.
J.Med.Chem., 56, 2013
4K5L
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BU of 4k5l by Molmil
Phosphonic Arginine Mimetics as Inhibitors of the M1 Aminopeptidases from Plasmodium falciparum
Descriptor: M1 family aminopeptidase, MAGNESIUM ION, ZINC ION, ...
Authors:McGowan, S.
Deposit date:2013-04-14
Release date:2013-06-12
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.91 Å)
Cite:Synthesis and Structure-Activity Relationships of Phosphonic Arginine Mimetics as Inhibitors of the M1 and M17 Aminopeptidases from Plasmodium falciparum.
J.Med.Chem., 56, 2013
4K5O
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BU of 4k5o by Molmil
Phosphonic Arginine Mimetics as Inhibitors of the M1 Aminopeptidases from Plasmodium falciparum
Descriptor: GLYCEROL, M1 family aminopeptidase, MAGNESIUM ION, ...
Authors:McGowan, S.
Deposit date:2013-04-15
Release date:2013-06-12
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Synthesis and Structure-Activity Relationships of Phosphonic Arginine Mimetics as Inhibitors of the M1 and M17 Aminopeptidases from Plasmodium falciparum.
J.Med.Chem., 56, 2013
4K3N
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BU of 4k3n by Molmil
Phosphonic Arginine Mimetics as Inhibitors of the M17 Aminopeptidases from Plasmodium falciparum
Descriptor: CARBONATE ION, M17 leucyl aminopeptidase, NONAETHYLENE GLYCOL, ...
Authors:McGowan, S.
Deposit date:2013-04-11
Release date:2013-06-12
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2 Å)
Cite:Synthesis and Structure-Activity Relationships of Phosphonic Arginine Mimetics as Inhibitors of the M1 and M17 Aminopeptidases from Plasmodium falciparum.
J.Med.Chem., 56, 2013

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